|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 135 for Dot1l

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.042s

Categories

Category: Publication
Type Details Score
Publication
First Author: Liao J
Year: 2020
Journal: Sci Rep
Title: Maternal DOT1L is dispensable for mouse development.
Volume: 10
Issue: 1
Pages: 20636
Publication
First Author: Nguyen AT
Year: 2011
Journal: Genes Dev
Title: DOT1L regulates dystrophin expression and is critical for cardiac function.
Volume: 25
Issue: 3
Pages: 263-74
Publication
First Author: Jones B
Year: 2008
Journal: PLoS Genet
Title: The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Volume: 4
Issue: 9
Pages: e1000190
Publication  
First Author: Monteagudo S
Year: 2017
Journal: Nat Commun
Title: DOT1L safeguards cartilage homeostasis and protects against osteoarthritis.
Volume: 8
Pages: 15889
Publication
First Author: Zhu B
Year: 2018
Journal: Nat Commun
Title: The protective role of DOT1L in UV-induced melanomagenesis.
Volume: 9
Issue: 1
Pages: 259
Publication
First Author: Kealy L
Year: 2020
Journal: Cell Rep
Title: The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses.
Volume: 33
Issue: 11
Pages: 108504
Publication
First Author: Feng Y
Year: 2010
Journal: Blood
Title: Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Volume: 116
Issue: 22
Pages: 4483-91
Publication
First Author: Aslam MA
Year: 2021
Journal: EMBO Rep
Title: Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Volume: 22
Issue: 2
Pages: e51184
Publication
First Author: Cheffer A
Year: 2023
Journal: Cereb Cortex
Title: DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.
Volume: 33
Issue: 19
Pages: 10272-10285
Publication  
First Author: Sutter PA
Year: 2021
Journal: Bone
Title: Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice.
Volume: 142
Pages: 115677
Publication
First Author: Jo SY
Year: 2011
Journal: Blood
Title: Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Volume: 117
Issue: 18
Pages: 4759-68
Publication    
First Author: Yi D
Year: 2020
Journal: Elife
Title: Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes.
Volume: 9
Publication  
First Author: Malla AB
Year: 2023
Journal: Development
Title: DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement.
Volume: 150
Issue: 9
Publication
First Author: Rau RE
Year: 2016
Journal: Blood
Title: DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Volume: 128
Issue: 7
Pages: 971-81
Publication
First Author: Kwesi-Maliepaard EM
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells.
Volume: 117
Issue: 34
Pages: 20706-20716
Publication
First Author: Yoo H
Year: 2020
Journal: Cell Death Dis
Title: Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function.
Volume: 11
Issue: 1
Pages: 14
Publication
First Author: Riedel SS
Year: 2016
Journal: J Clin Invest
Title: MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Volume: 126
Issue: 4
Pages: 1438-50
Publication
First Author: Willemsen L
Year: 2022
Journal: Cell Rep
Title: DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.
Volume: 41
Issue: 8
Pages: 111703
Publication  
First Author: Malcom CA
Year: 2021
Journal: Front Cell Dev Biol
Title: Primitive Erythropoiesis in the Mouse is Independent of DOT1L Methyltransferase Activity.
Volume: 9
Pages: 813503
Publication  
First Author: Feng Y
Year: 2022
Journal: Int J Mol Sci
Title: DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin.
Volume: 23
Issue: 9
Publication
First Author: Ooga M
Year: 2013
Journal: Biol Reprod
Title: Involvement of DOT1L in the remodeling of heterochromatin configuration during early preimplantation development in mice.
Volume: 89
Issue: 6
Pages: 145
Publication
First Author: Wang J
Year: 2021
Journal: J Am Heart Assoc
Title: Histone Methyltransferase Dot1L Contributes to RIPK1 Kinase-Dependent Apoptosis in Cerebral Ischemia/Reperfusion.
Volume: 10
Issue: 23
Pages: e022791
Publication
First Author: Yang D
Year: 2022
Journal: Cell Death Dis
Title: The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis.
Volume: 13
Issue: 1
Pages: 60
Publication
First Author: Appiah B
Year: 2023
Journal: EMBO Rep
Title: DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression.
Volume: 24
Issue: 8
Pages: e56233
Publication
First Author: Scheer S
Year: 2020
Journal: Cell Rep
Title: The Methyltransferase DOT1L Controls Activation and Lineage Integrity in CD4+ T Cells during Infection and Inflammation.
Volume: 33
Issue: 11
Pages: 108505
Publication
First Author: Jo SY
Year: 2020
Journal: JBMR Plus
Title: The Role of Dot1l in Prenatal and Postnatal Murine Chondrocytes and Trabecular Bone.
Volume: 4
Issue: 2
Pages: e10254
Publication
First Author: Bovio PP
Year: 2019
Journal: Mol Neurobiol
Title: Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
Volume: 56
Issue: 6
Pages: 4273-4287
Publication
First Author: Chen CW
Year: 2015
Journal: Nat Med
Title: DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Volume: 21
Issue: 4
Pages: 335-43
Publication
First Author: Xiao Z
Year: 2016
Journal: Exp Cell Res
Title: Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice.
Volume: 344
Issue: 2
Pages: 167-75
Publication
First Author: Li S
Year: 2023
Journal: Stem Cell Reports
Title: DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury.
Volume: 18
Issue: 9
Pages: 1841-1853
Publication
First Author: Ontoso D
Year: 2014
Journal: Chromosoma
Title: Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.
Volume: 123
Issue: 1-2
Pages: 147-64
Publication
First Author: Cattaneo P
Year: 2022
Journal: Nat Commun
Title: DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.
Volume: 13
Issue: 1
Pages: 7444
Publication  
First Author: Van Heesbeen HJ
Year: 2023
Journal: Int J Mol Sci
Title: Neuronal Dot1l Activity Acts as a Mitochondrial Gene-Repressor Associated with Human Brain Aging via H3K79 Hypermethylation.
Volume: 24
Issue: 2
Publication
First Author: Gray de Cristoforis A
Year: 2020
Journal: Mol Brain
Title: Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.
Volume: 13
Issue: 1
Pages: 85
Publication
First Author: Franz H
Year: 2019
Journal: Nucleic Acids Res
Title: DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.
Volume: 47
Issue: 1
Pages: 168-183
Publication
First Author: Wang F
Year: 2021
Journal: Epigenetics
Title: Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.
Volume: 16
Issue: 11
Pages: 1235-1250
Publication
First Author: FitzGerald J
Year: 2011
Journal: PLoS One
Title: Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
Volume: 6
Issue: 2
Pages: e14714
Publication
First Author: Nguyen AT
Year: 2011
Journal: Blood
Title: DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Volume: 117
Issue: 25
Pages: 6912-22
Publication
First Author: Deshpande AJ
Year: 2014
Journal: Cancer Cell
Title: AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Volume: 26
Issue: 6
Pages: 896-908
Publication  
First Author: Lin H
Year: 2023
Journal: Development
Title: The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.
Volume: 150
Issue: 9
Publication
First Author: Vlaming H
Year: 2019
Journal: EMBO J
Title: Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
Volume: 38
Issue: 14
Pages: e101564
Publication
First Author: Chen L
Year: 2013
Journal: Leukemia
Title: Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
Volume: 27
Issue: 4
Pages: 813-22
Publication
First Author: Steger DJ
Year: 2008
Journal: Mol Cell Biol
Title: DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
Volume: 28
Issue: 8
Pages: 2825-39
Publication
First Author: Bernt KM
Year: 2011
Journal: Cancer Cell
Title: MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Volume: 20
Issue: 1
Pages: 66-78
Publication
First Author: Cornelis FMF
Year: 2019
Journal: Osteoarthritis Cartilage
Title: Increased susceptibility to develop spontaneous and post-traumatic osteoarthritis in Dot1l-deficient mice.
Volume: 27
Issue: 3
Pages: 513-525
Publication
First Author: Chang MJ
Year: 2010
Journal: Cancer Res
Title: Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Volume: 70
Issue: 24
Pages: 10234-42
Publication
First Author: Wu H
Year: 2013
Journal: J Am Soc Nephrol
Title: Aqp2-expressing cells give rise to renal intercalated cells.
Volume: 24
Issue: 2
Pages: 243-52
Publication
First Author: Ho LL
Year: 2013
Journal: Mol Cell Biol
Title: DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
Volume: 33
Issue: 9
Pages: 1735-45
Publication
First Author: Deshpande AJ
Year: 2013
Journal: Blood
Title: Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Volume: 121
Issue: 13
Pages: 2533-41
Publication
First Author: Wu H
Year: 2013
Journal: PLoS One
Title: Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2.
Volume: 8
Issue: 1
Pages: e53342
Publication
First Author: Zhang W
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene.
Volume: 304
Issue: 4
Pages: F367-75
Publication
First Author: Mahmoudi T
Year: 2010
Journal: PLoS Biol
Title: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.
Volume: 8
Issue: 11
Pages: e1000539
Publication
First Author: Okada Y
Year: 2005
Journal: Cell
Title: hDOT1L links histone methylation to leukemogenesis.
Volume: 121
Issue: 2
Pages: 167-78
Publication
First Author: Zhang W
Year: 2004
Journal: Biochem J
Title: Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase.
Volume: 377
Issue: Pt 3
Pages: 641-51
Publication  
First Author: Gobé C
Year: 2023
Journal: Genes (Basel)
Title: Generation and Characterization of a Transgenic Mouse That Specifically Expresses the Cre Recombinase in Spermatids.
Volume: 14
Issue: 5
Publication  
First Author: Jo SY
Year: 2023
Journal: Bone
Title: In vivo intra-articular contrast enhanced μCT imaging of mouse knee cartilage.
Volume: 167
Pages: 116632
Publication
First Author: Bian Y
Year: 2020
Journal: Nature
Title: Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Volume: 585
Issue: 7824
Pages: 277-282
Publication
First Author: Mueller D
Year: 2009
Journal: PLoS Biol
Title: Misguided transcriptional elongation causes mixed lineage leukemia.
Volume: 7
Issue: 11
Pages: e1000249
Publication
First Author: Alpatov R
Year: 2014
Journal: Cell
Title: A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Volume: 157
Issue: 4
Pages: 869-81
Publication
First Author: Zhou Q
Year: 2012
Journal: PLoS One
Title: Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats.
Volume: 7
Issue: 10
Pages: e47360
Publication
First Author: Zhang D
Year: 2009
Journal: J Biol Chem
Title: Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct.
Volume: 284
Issue: 31
Pages: 20917-26
Publication
First Author: Zhang X
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Mineralocorticoid receptor antagonizes Dot1a-Af9 complex to increase αENaC transcription.
Volume: 305
Issue: 10
Pages: F1436-44
Publication
First Author: Reisenauer MR
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels.
Volume: 299
Issue: 1
Pages: F63-76
Publication    
First Author: Pereira M
Year: 2020
Journal: Elife
Title: A trans-eQTL network regulates osteoclast multinucleation and bone mass.
Volume: 9
Publication
First Author: Fisher CL
Year: 2017
Journal: Nucleic Acids Res
Title: An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.
Volume: 45
Issue: 21
Pages: e174
Publication
First Author: Ko HR
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control.
Volume: 116
Issue: 49
Pages: 24852-24860
Publication
First Author: Wajapeyee N
Year: 2013
Journal: Genes Dev
Title: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Volume: 27
Issue: 20
Pages: 2221-6
Publication  
First Author: Zhang F
Year: 2021
Journal: Front Cell Dev Biol
Title: Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.
Volume: 9
Pages: 642931
Publication
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform