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Search results 1 to 100 out of 403 for Mycn

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Category: Publication
Type Details Score
Publication
First Author: Swartling FJ
Year: 2010
Journal: Genes Dev
Title: Pleiotropic role for MYCN in medulloblastoma.
Volume: 24
Issue: 10
Pages: 1059-72
Publication
First Author: Chanthery YH
Year: 2012
Journal: Sci Transl Med
Title: Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma.
Volume: 4
Issue: 115
Pages: 115ra3
Publication
First Author: Olsen RR
Year: 2017
Journal: Oncogene
Title: MYCN induces neuroblastoma in primary neural crest cells.
Volume: 36
Issue: 35
Pages: 5075-5082
Publication
First Author: Harmelink C
Year: 2013
Journal: Dev Biol
Title: Myocardial Mycn is essential for mouse ventricular wall morphogenesis.
Volume: 373
Issue: 1
Pages: 53-63
Publication
First Author: Berry T
Year: 2012
Journal: Cancer Cell
Title: The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma.
Volume: 22
Issue: 1
Pages: 117-30
Publication
First Author: Chesler L
Year: 2006
Journal: Cancer Res
Title: Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.
Volume: 66
Issue: 16
Pages: 8139-46
Publication
First Author: Mirzamohammadi F
Year: 2018
Journal: Nat Commun
Title: Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models.
Volume: 9
Issue: 1
Pages: 1352
Publication
First Author: DeWitt J
Year: 2014
Journal: Dev Neurosci
Title: Ciliary neurotrophic factor reduces the proliferation and promotes the differentiation of TH- MYCN transformed sympathoadrenal progenitors.
Volume: 36
Issue: 5
Pages: 422-31
Publication
First Author: Alvarez-Rodríguez R
Year: 2009
Journal: J Cell Sci
Title: Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity.
Volume: 122
Issue: Pt 5
Pages: 595-9
Publication
First Author: Yang R
Year: 2022
Journal: Hum Mol Genet
Title: Mycn deficiency underlies the development of orofacial clefts in mice and humans.
Volume: 31
Issue: 5
Pages: 803-815
Publication
First Author: Holdhof D
Year: 2021
Journal: Cerebellum
Title: Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration.
Volume: 20
Issue: 3
Pages: 410-419
Publication
First Author: Grunblatt E
Year: 2020
Journal: Genes Dev
Title: MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Volume: 34
Issue: 17-18
Pages: 1210-1226
Publication      
First Author: Kato K
Year: 2018
Journal: J Med Genet
Title: MYCN de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome.
Publication
First Author: Ahmad Z
Year: 2015
Journal: PLoS One
Title: Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastoma.
Volume: 10
Issue: 3
Pages: e0119834
Publication
First Author: Swartling FJ
Year: 2012
Journal: Cancer Cell
Title: Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
Volume: 21
Issue: 5
Pages: 601-13
Publication
First Author: Hogarty MD
Year: 2012
Journal: Cancer Cell
Title: PI3King on MYCN to improve neuroblastoma therapeutics.
Volume: 21
Issue: 2
Pages: 145-7
Publication
First Author: Wu N
Year: 2017
Journal: J Clin Invest
Title: A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence.
Volume: 127
Issue: 3
Pages: 888-898
Publication
First Author: Bell E
Year: 2010
Journal: Cancer Lett
Title: MYCN oncoprotein targets and their therapeutic potential.
Volume: 293
Issue: 2
Pages: 144-57
Publication
First Author: Yang CL
Year: 2020
Journal: Oncotarget
Title: Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity.
Volume: 11
Issue: 24
Pages: 2357-2371
Publication
First Author: Westermark UK
Year: 2011
Journal: Semin Cancer Biol
Title: The MYCN oncogene and differentiation in neuroblastoma.
Volume: 21
Issue: 4
Pages: 256-66
Publication  
First Author: Sendra M
Year: 2023
Journal: Development
Title: Cre recombinase microinjection for single-cell tracing and localised gene targeting.
Volume: 150
Issue: 3
Publication  
First Author: Jiao X
Year: 2021
Journal: Int J Mol Sci
Title: Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice.
Volume: 22
Issue: 6
Publication
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
Publication
First Author: King B
Year: 2016
Journal: Nat Immunol
Title: The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.
Volume: 17
Issue: 11
Pages: 1312-1321
Publication
First Author: Ueda T
Year: 2016
Journal: Oncogene
Title: ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.
Volume: 35
Issue: 34
Pages: 4447-58
Publication
First Author: Nakaguro M
Year: 2015
Journal: Cancer Sci
Title: Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.
Volume: 106
Issue: 3
Pages: 237-43
Publication
First Author: Valli E
Year: 2012
Journal: Biochim Biophys Acta
Title: CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.
Volume: 1819
Issue: 11-12
Pages: 1173-85
Publication
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
Publication
First Author: Tavana O
Year: 2016
Journal: Nat Med
Title: HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.
Volume: 22
Issue: 10
Pages: 1180-1186
Publication
First Author: Varlakhanova NV
Year: 2010
Journal: Differentiation
Title: myc maintains embryonic stem cell pluripotency and self-renewal.
Volume: 80
Issue: 1
Pages: 9-19
Publication  
First Author: Klett C
Year: 1991
Journal: Mouse Genome
Title: Mapping of Nmyc-1 to mouse Chromosome 12, band A3/B.
Volume: 89
Pages: 275
Publication
First Author: Terrile M
Year: 2011
Journal: PLoS One
Title: miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs.
Volume: 6
Issue: 12
Pages: e28356
Publication
First Author: Seya D
Year: 2021
Journal: Dev Growth Differ
Title: A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis.
Volume: 63
Issue: 1
Pages: 82-92
Publication
First Author: Calao M
Year: 2013
Journal: Oncogene
Title: Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.
Volume: 32
Issue: 31
Pages: 3616-26
Publication  
First Author: Muñoz-Martín N
Year: 2019
Journal: Development
Title: Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.
Volume: 146
Issue: 3
Publication  
First Author: Mastromina I
Year: 2018
Journal: Development
Title: Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Volume: 145
Issue: 14
Publication
First Author: Li J
Year: 2021
Journal: J Am Soc Nephrol
Title: Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.
Volume: 32
Issue: 11
Pages: 2815-2833
Publication
First Author: Sun Q
Year: 2019
Journal: Dev Biol
Title: SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.
Volume: 452
Issue: 1
Pages: 1-7
Publication
First Author: Puissant A
Year: 2013
Journal: Cancer Discov
Title: Targeting MYCN in neuroblastoma by BET bromodomain inhibition.
Volume: 3
Issue: 3
Pages: 308-23
Publication
First Author: Blank MC
Year: 2011
Journal: Development
Title: Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.
Volume: 138
Issue: 6
Pages: 1207-16
Publication
First Author: Gustafson WC
Year: 2014
Journal: Cancer Cell
Title: Drugging MYCN through an allosteric transition in Aurora kinase A.
Volume: 26
Issue: 3
Pages: 414-427
Publication
First Author: DePinho RA
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Structure and expression of the murine N-myc gene.
Volume: 83
Issue: 6
Pages: 1827-31
Publication
First Author: Taya Y
Year: 1986
Journal: EMBO J
Title: Nucleotide sequence of the coding region of the mouse N-myc gene.
Volume: 5
Issue: 6
Pages: 1215-9
Publication
First Author: Katoh K
Year: 1988
Journal: Nucleic Acids Res
Title: Complete nucleotide sequence and exon-intron boundaries of the 5' non-coding region of the mouse N-myc gene.
Volume: 16
Issue: 8
Pages: 3589
Publication
First Author: Hackett CS
Year: 2014
Journal: Cell Rep
Title: Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.
Volume: 9
Issue: 3
Pages: 1034-46
Publication
First Author: Kawakubo N
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Natural antibody against neuroblastoma of TH-MYCN transgenic mice does not correlate with spontaneous regression.
Volume: 503
Issue: 3
Pages: 1666-1673
Publication
First Author: Sun R
Year: 2012
Journal: Nucleic Acids Res
Title: Inducible and reversible regulation of endogenous gene in mouse.
Volume: 40
Issue: 21
Pages: e166
Publication
First Author: Nagy A
Year: 1998
Journal: Curr Biol
Title: Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.
Volume: 8
Issue: 11
Pages: 661-4
Publication
First Author: Heine VM
Year: 2010
Journal: Cancer Res
Title: Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.
Volume: 70
Issue: 13
Pages: 5220-5
Publication
First Author: Moens CB
Year: 1992
Journal: Genes Dev
Title: A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung.
Volume: 6
Issue: 5
Pages: 691-704
Publication
First Author: Bates CM
Year: 2000
Journal: Dev Biol
Title: Role of N-myc in the developing mouse kidney.
Volume: 222
Issue: 2
Pages: 317-25
Publication
First Author: Ma M
Year: 2014
Journal: Dev Growth Differ
Title: Dynamic expression of N-myc in mouse embryonic development using an enhanced green fluorescent protein reporter gene in the N-myc locus.
Volume: 56
Issue: 2
Pages: 152-60
Publication
First Author: Stanton BR
Year: 1990
Journal: Mol Cell Biol
Title: Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells.
Volume: 10
Issue: 12
Pages: 6755-8
Publication
First Author: Sawai S
Year: 1991
Journal: New Biol
Title: Embryonic lethality resulting from disruption of both N-myc alleles in mouse zygotes.
Volume: 3
Issue: 9
Pages: 861-9
Publication
First Author: Sawai S
Year: 1993
Journal: Development
Title: Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse.
Volume: 117
Issue: 4
Pages: 1445-55
Publication
First Author: Charron J
Year: 1992
Journal: Genes Dev
Title: Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.
Volume: 6
Issue: 12A
Pages: 2248-57
Publication
First Author: Mugrauer G
Year: 1988
Journal: J Cell Biol
Title: N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization.
Volume: 107
Issue: 4
Pages: 1325-35
Publication
First Author: Charron J
Year: 2002
Journal: Pediatr Res
Title: Identification of N-myc regulatory regions involved in embryonic expression.
Volume: 51
Issue: 1
Pages: 48-56
Publication
First Author: Samant SA
Year: 1999
Journal: Leuk Res
Title: Mutational analysis of transgenic mouse B cell lymphomas: indication of a Trp53-independent pathway in tumor progression.
Volume: 23
Issue: 10
Pages: 939-46
Publication
First Author: Yancopoulos GD
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: N-myc can cooperate with ras to transform normal cells in culture.
Volume: 82
Issue: 16
Pages: 5455-9
Publication
First Author: van Lohuizen M
Year: 1989
Journal: EMBO J
Title: N-myc is frequently activated by proviral insertion in MuLV-induced T cell lymphomas.
Volume: 8
Issue: 1
Pages: 133-6
Publication
First Author: Romand R
Year: 1994
Journal: Hear Res
Title: N-myc expression in the embryonic cochlea of the mouse.
Volume: 72
Issue: 1-2
Pages: 53-8
Publication
First Author: Sheppard RD
Year: 1998
Journal: Oncogene
Title: Transgenic N-myc mouse model for indolent B cell lymphoma: tumor characterization and analysis of genetic alterations in spontaneous and retrovirally accelerated tumors.
Volume: 17
Issue: 16
Pages: 2073-85
Publication
First Author: Dildrop R
Year: 1989
Journal: EMBO J
Title: IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression.
Volume: 8
Issue: 4
Pages: 1121-8
Publication
First Author: Shimono A
Year: 1996
Journal: Dev Growth Differ
Title: Requirement of N-myc protein down-regulation for neuronal differentiation in the spinal cord.
Volume: 38
Issue: 6
Pages: 707-716
Publication
First Author: Recio JA
Year: 1999
Journal: Mol Carcinog
Title: cDNA isolation, expression, and chromosomal localization of the mouse pcph proto-oncogene.
Volume: 26
Issue: 2
Pages: 130-6
Publication
First Author: Cox DR
Year: 1988
Journal: Cytogenet Cell Genet
Title: A functional mouse ornithine decarboxylase gene (Odc) maps to chromosome 12: further evidence of homoeology between mouse chromosome 12 and the short arm of human chromosome 2.
Volume: 48
Issue: 2
Pages: 92-4
Publication
First Author: Weiss WA
Year: 1997
Journal: EMBO J
Title: Targeted expression of MYCN causes neuroblastoma in transgenic mice.
Volume: 16
Issue: 11
Pages: 2985-95
Publication
First Author: Molenaar JJ
Year: 2012
Journal: Nat Genet
Title: LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Volume: 44
Issue: 11
Pages: 1199-206
Publication
First Author: Slack A
Year: 2005
Journal: Cancer Lett
Title: MDM2 as MYCN transcriptional target: implications for neuroblastoma pathogenesis.
Volume: 228
Issue: 1-2
Pages: 21-7
Publication
First Author: Zhao X
Year: 2008
Journal: Nat Cell Biol
Title: The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein.
Volume: 10
Issue: 6
Pages: 643-53
Publication
First Author: Shimono A
Year: 1999
Journal: Mech Dev
Title: N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant.
Volume: 83
Issue: 1-2
Pages: 39-52
Publication  
First Author: Kopecky BJ
Year: 2012
Journal: Brain Res
Title: N-Myc and L-Myc are essential for hair cell formation but not maintenance.
Volume: 1484
Pages: 1-14
Publication
First Author: Kessler JD
Year: 2009
Journal: Genes Dev
Title: N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.
Volume: 23
Issue: 2
Pages: 157-70
Publication
First Author: Thomas WD
Year: 2009
Journal: Oncogene
Title: Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
Volume: 28
Issue: 13
Pages: 1605-15
Publication
First Author: Zhang SL
Year: 2007
Journal: Pediatr Nephrol
Title: Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop.
Volume: 22
Issue: 6
Pages: 813-24
Publication
First Author: Ellmeier W
Year: 1995
Journal: Dev Dyn
Title: Expression of the helix-loop-helix gene Id3 during murine embryonic development.
Volume: 203
Issue: 2
Pages: 163-73
Publication
First Author: Dorstyn L
Year: 2019
Journal: Cell Death Dis
Title: Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling.
Volume: 10
Issue: 2
Pages: 56
Publication
First Author: Knoepfler PS
Year: 2006
Journal: EMBO J
Title: Myc influences global chromatin structure.
Volume: 25
Issue: 12
Pages: 2723-34
Publication
First Author: Pshenichnaya I
Year: 2012
Journal: Pigment Cell Melanoma Res
Title: Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc.
Volume: 25
Issue: 3
Pages: 312-25
Publication
First Author: Stanton BR
Year: 1992
Journal: Genes Dev
Title: Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.
Volume: 6
Issue: 12A
Pages: 2235-47
Publication
First Author: Smith KN
Year: 2010
Journal: Cell Stem Cell
Title: Myc represses primitive endoderm differentiation in pluripotent stem cells.
Volume: 7
Issue: 3
Pages: 343-54
Publication
First Author: Laurenti E
Year: 2008
Journal: Cell Stem Cell
Title: Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.
Volume: 3
Issue: 6
Pages: 611-24
Publication
First Author: Martínez-Cerdeño V
Year: 2012
Journal: PLoS One
Title: N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.
Volume: 7
Issue: 6
Pages: e39456
Publication
First Author: Downs KM
Year: 1989
Journal: Genes Dev
Title: Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo.
Volume: 3
Issue: 6
Pages: 860-9
Publication
First Author: Jakobovits A
Year: 1985
Journal: Nature
Title: Expression of N-myc in teratocarcinoma stem cells and mouse embryos.
Volume: 318
Issue: 6042
Pages: 188-91
Publication
First Author: Möröy T
Year: 1990
Journal: EMBO J
Title: IgH enhancer deregulated expression of L-myc: abnormal T lymphocyte development and T cell lymphomagenesis.
Volume: 9
Issue: 11
Pages: 3659-66
Publication
First Author: Hirning U
Year: 1991
Journal: Mech Dev
Title: A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis.
Volume: 33
Issue: 2
Pages: 119-25
Publication
First Author: Mukherjee B
Year: 1992
Journal: Genes Dev
Title: Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.
Volume: 6
Issue: 8
Pages: 1480-92
Publication
First Author: Ingvarsson S
Year: 1988
Journal: Oncogene
Title: Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells.
Volume: 3
Issue: 6
Pages: 679-85
Publication
First Author: Axelson H
Year: 1994
Journal: Genes Chromosomes Cancer
Title: Juxtaposition of N-myc and Ig kappa through a reciprocal t(6;12) translocation in a mouse plasmacytoma.
Volume: 11
Issue: 2
Pages: 85-90
Publication
First Author: Goji J
Year: 1995
Journal: Am J Pathol
Title: Expression of c-ErbB2 in human neuroblastoma tissues, adrenal medulla adjacent to tumor, and developing mouse neural crest cells.
Volume: 146
Issue: 3
Pages: 660-72
Publication
First Author: Broad TE
Year: 1995
Journal: Anim Genet
Title: Six loci mapped on to human chromosome 2p are assigned to sheep chromosome 3p.
Volume: 26
Issue: 2
Pages: 85-90
Publication
First Author: Neri F
Year: 2012
Journal: Mol Cell Biol
Title: Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells.
Volume: 32
Issue: 4
Pages: 840-51
Publication
First Author: Kanatsu-Shinohara M
Year: 2016
Journal: Genes Dev
Title: Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal.
Volume: 30
Issue: 23
Pages: 2637-2648
Publication
First Author: Kato K
Year: 1991
Journal: Dev Growth Differ
Title: Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo.
Volume: 33
Issue: 1
Pages: 29-36
Publication
First Author: Cerretti DP
Year: 1999
Journal: Cytokine
Title: Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Volume: 11
Issue: 8
Pages: 541-51
Publication
First Author: Hurlin PJ
Year: 1997
Journal: Genes Dev
Title: Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.
Volume: 11
Issue: 1
Pages: 44-58
Publication
First Author: Okuda T
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc.
Volume: 266
Issue: 1
Pages: 208-15
Publication
First Author: ten Berge D
Year: 2008
Journal: Development
Title: Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development.
Volume: 135
Issue: 19
Pages: 3247-57