Type |
Details |
Score |
Publication |
First Author: |
Leo D |
Year: |
2013 |
Journal: |
Cell Tissue Res |
Title: |
Transgenic mouse models for ADHD. |
Volume: |
354 |
Issue: |
1 |
Pages: |
259-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heng JI |
Year: |
2008 |
Journal: |
Nature |
Title: |
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. |
Volume: |
455 |
Issue: |
7209 |
Pages: |
114-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Futatsugi A |
Year: |
2012 |
Journal: |
Cell Cycle |
Title: |
Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons. |
Volume: |
11 |
Issue: |
8 |
Pages: |
1603-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rakić S |
Year: |
2009 |
Journal: |
Cereb Cortex |
Title: |
Cortical interneurons require p35/Cdk5 for their migration and laminar organization. |
Volume: |
19 |
Issue: |
8 |
Pages: |
1857-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong JL |
Year: |
2003 |
Journal: |
Dev Dyn |
Title: |
Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent. |
Volume: |
228 |
Issue: |
1 |
Pages: |
121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. |
Volume: |
30 |
Issue: |
15 |
Pages: |
5219-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikeda Y |
Year: |
2011 |
Journal: |
Gene Expr Patterns |
Title: |
Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain. |
Volume: |
11 |
Issue: |
1-2 |
Pages: |
64-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bayam E |
Year: |
2015 |
Journal: |
BMC Genomics |
Title: |
Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation. |
Volume: |
16 |
|
Pages: |
681 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramirez M |
Year: |
2023 |
Journal: |
BMC Genomics |
Title: |
Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis. |
Volume: |
24 |
Issue: |
1 |
Pages: |
351 |
|
•
•
•
•
•
|
Publication |
First Author: |
Odajima J |
Year: |
2011 |
Journal: |
Dev Cell |
Title: |
Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. |
Volume: |
21 |
Issue: |
4 |
Pages: |
655-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ke Y |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. |
Volume: |
27 |
Issue: |
19 |
Pages: |
6706-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang Y |
Year: |
2006 |
Journal: |
Genes Dev |
Title: |
Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. |
Volume: |
20 |
Issue: |
7 |
Pages: |
836-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasamoto K |
Year: |
2017 |
Journal: |
Dev Neurobiol |
Title: |
Cdk5 is required for the positioning and survival of GABAergic neurons in developing mouse striatum. |
Volume: |
77 |
Issue: |
4 |
Pages: |
483-492 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoerder-Suabedissen A |
Year: |
2009 |
Journal: |
Cereb Cortex |
Title: |
Novel markers reveal subpopulations of subplate neurons in the murine cerebral cortex. |
Volume: |
19 |
Issue: |
8 |
Pages: |
1738-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohshima T |
Year: |
2002 |
Journal: |
J Neurosci |
Title: |
Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. |
Volume: |
22 |
Issue: |
10 |
Pages: |
4036-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eguchi T |
Year: |
2024 |
Journal: |
iScience |
Title: |
Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice. |
Volume: |
27 |
Issue: |
2 |
Pages: |
108997 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugitani Y |
Year: |
2002 |
Journal: |
Genes Dev |
Title: |
Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. |
Volume: |
16 |
Issue: |
14 |
Pages: |
1760-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
McEvilly RJ |
Year: |
2002 |
Journal: |
Science |
Title: |
Transcriptional regulation of cortical neuron migration by POU domain factors. |
Volume: |
295 |
Issue: |
5559 |
Pages: |
1528-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. |
Volume: |
105 |
Issue: |
27 |
Pages: |
9397-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
DÃaz-Ruiz C |
Year: |
2008 |
Journal: |
Mol Cell Neurosci |
Title: |
Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants. |
Volume: |
39 |
Issue: |
4 |
Pages: |
519-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rakić S |
Year: |
2015 |
Journal: |
Cereb Cortex |
Title: |
Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons. |
Volume: |
25 |
Issue: |
4 |
Pages: |
991-1003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liebl J |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. |
Volume: |
6 |
|
Pages: |
7274 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hevner RF |
Year: |
2001 |
Journal: |
Neuron |
Title: |
Tbr1 regulates differentiation of the preplate and layer 6. |
Volume: |
29 |
Issue: |
2 |
Pages: |
353-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arnold SJ |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. |
Volume: |
22 |
Issue: |
18 |
Pages: |
2479-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh S |
Year: |
2016 |
Journal: |
Elife |
Title: |
Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX Interspecific Backcross BSS and BSB Public Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brady KP |
Year: |
1997 |
Journal: |
Genome Res |
Title: |
Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. |
Volume: |
7 |
Issue: |
11 |
Pages: |
1085-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshaw S |
Year: |
2004 |
Journal: |
PLoS Biol |
Title: |
Genomic analysis of mouse retinal development. |
Volume: |
2 |
Issue: |
9 |
Pages: |
E247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
cyclin dependent kinase 5, regulatory subunit 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Ashok B Kulkarni |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka T |
Year: |
2001 |
Journal: |
J Neurosci |
Title: |
Neuronal cyclin-dependent kinase 5 activity is critical for survival. |
Volume: |
21 |
Issue: |
2 |
Pages: |
550-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
80
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
112
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
145
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
124
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
140
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
487
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2007 |
Journal: |
Cancer Cell |
Title: |
LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB. |
Volume: |
12 |
Issue: |
3 |
Pages: |
239-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen J |
Year: |
2002 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart. |
Volume: |
294 |
Issue: |
1 |
Pages: |
161-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang H |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. |
Volume: |
280 |
Issue: |
21 |
Pages: |
20651-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang H |
Year: |
2009 |
Journal: |
Cell Res |
Title: |
Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation. |
Volume: |
19 |
Issue: |
4 |
Pages: |
458-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie YH |
Year: |
2003 |
Journal: |
Cell Res |
Title: |
Cloning and characterization of human IC53-2, a novel CDK5 activator binding protein. |
Volume: |
13 |
Issue: |
2 |
Pages: |
83-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wamsley JJ |
Year: |
2017 |
Journal: |
Cell Cycle |
Title: |
LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro. |
Volume: |
16 |
Issue: |
2 |
Pages: |
213-223 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
CDK5RAP3 (also known as C53 or LZAP) serves as a probable tumour suppressor initially identified as a CDK5R1 interactor controllingcell proliferation [, ]. It negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation [, ]. It also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint [, ]. It has been shown to bind Wip1 and stimulates its phosphatase activity []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu J |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling. |
Volume: |
285 |
Issue: |
20 |
Pages: |
15126-36 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|