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Search results 201 to 300 out of 2736 for Psen1

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Type Details Score
Publication
28511979 | J:249623
 
First Author: Davis KE
Year: 2017
Journal: Behav Brain Res
Title: Water and T-maze protocols are equally efficient methods to assess spatial memory in 3xTg Alzheimer's disease mice.
Volume: 331
Pages: 54-66
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31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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25857617 | J:230543
First Author: Mota SI
Year: 2015
Journal: Biochim Biophys Acta
Title: Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.
Volume: 1852
Issue: 7
Pages: 1428-41
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Publication
28688899 | J:249714
 
First Author: Velazquez R
Year: 2017
Journal: Neurobiol Aging
Title: Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.
Volume: 58
Pages: 1-13
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Publication
26939023 | J:249723
First Author: Makani V
Year: 2016
Journal: PLoS One
Title: BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR.
Volume: 11
Issue: 3
Pages: e0149715
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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Publication
36915108 | J:334972
First Author: Wang RP
Year: 2023
Journal: J Neuroinflammation
Title: IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer's disease.
Volume: 20
Issue: 1
Pages: 71
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Publication
34896306 | J:319782
 
First Author: Nazari HK
Year: 2022
Journal: Exp Eye Res
Title: Age dependence of retinal vascular plexus attenuation in the triple transgenic mouse model of Alzheimer's disease.
Volume: 214
Pages: 108879
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Publication
36902113 | J:348454
 
First Author: Webberley TS
Year: 2023
Journal: Int J Mol Sci
Title: Assessment of Lab4P Probiotic Effects on Cognition in 3xTg-AD Alzheimer's Disease Model Mice and the SH-SY5Y Neuronal Cell Line.
Volume: 24
Issue: 5
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Publication
31150495 | J:276449
First Author: Esquerda-Canals G
Year: 2019
Journal: PLoS One
Title: Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragment.
Volume: 14
Issue: 5
Pages: e0217793
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Publication
28865961 | J:307498
First Author: Sah SK
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease.
Volume: 493
Issue: 1
Pages: 731-736
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Publication
26385257 | J:244334
 
First Author: Clark JK
Year: 2015
Journal: Neurobiol Learn Mem
Title: Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice.
Volume: 125
Pages: 152-162
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Publication
35373908 | J:327512
First Author: Ring J
Year: 2022
Journal: EMBO Mol Med
Title: The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity.
Volume: 14
Issue: 5
Pages: e13952
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Publication
32114116 | J:289388
 
First Author: Acero G
Year: 2020
Journal: Neurosci Lett
Title: Novel monoclonal antibody 3B8 specifically recognizes pyroglutamate-modified amyloid β 3-42 peptide in brain of AD patients and 3xTg-AD transgenic mice.
Volume: 724
Pages: 134876
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Publication
32082134 | J:288901
 
First Author: Yao X
Year: 2019
Journal: Front Aging Neurosci
Title: Loss of miR-369 Promotes Tau Phosphorylation by Targeting the Fyn and Serine/Threonine-Protein Kinase 2 Signaling Pathways in Alzheimer's Disease Mice.
Volume: 11
Pages: 365
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33841077 | J:348494
 
First Author: Cochard LM
Year: 2021
Journal: Front Neurosci
Title: Manipulation of EGFR-Induced Signaling for the Recruitment of Quiescent Neural Stem Cells in the Adult Mouse Forebrain.
Volume: 15
Pages: 621076
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24990149 | J:215460
First Author: Guedes JR
Year: 2014
Journal: Hum Mol Genet
Title: Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.
Volume: 23
Issue: 23
Pages: 6286-301
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29577984 | J:260969
 
First Author: Duan J
Year: 2018
Journal: Mol Cell Neurosci
Title: Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons.
Volume: 89
Pages: 1-8
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22688056 | J:186995
First Author: Medeiros R
Year: 2012
Journal: Am J Pathol
Title: Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice.
Volume: 181
Issue: 2
Pages: 616-25
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30031227 | J:348501
First Author: Tramutola A
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.
Volume: 1864
Issue: 10
Pages: 3309-3321
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Publication
37221202 | J:348485
First Author: Walek KW
Year: 2023
Journal: Nat Commun
Title: Near-lifespan longitudinal tracking of brain microvascular morphology, topology, and flow in male mice.
Volume: 14
Issue: 1
Pages: 2982
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Publication
36241022 | J:348507
 
First Author: Valle ML
Year: 2022
Journal: Mol Cell Neurosci
Title: Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology.
Volume: 123
Pages: 103785
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Publication
35140584 | J:348535
 
First Author: Javonillo DI
Year: 2021
Journal: Front Neurosci
Title: Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 15
Pages: 785276
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22995307 | J:190096
First Author: Chakravarthy B
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Reduction of the immunostainable length of the hippocampal dentate granule cells' primary cilia in 3xAD-transgenic mice producing human Aβ(1-42) and tau.
Volume: 427
Issue: 1
Pages: 218-22
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Publication
31987831 | J:292729
 
First Author: Chen C
Year: 2020
Journal: Exp Neurol
Title: Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.
Volume: 327
Pages: 113210
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Publication
36577656 | J:348513
First Author: Hakim MA
Year: 2023
Journal: Microcirculation
Title: K(IR) channel regulation of electrical conduction along cerebrovascular endothelium: Enhanced modulation during Alzheimer's disease.
Volume: 30
Issue: 1
Pages: e12797
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Publication
30967770 | J:277729
 
First Author: Manno FAM
Year: 2019
Journal: Front Aging Neurosci
Title: Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 39
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Publication
24842003 | J:215510
 
First Author: Coronas-Sámano G
Year: 2014
Journal: Brain Res
Title: Deficits in odor-guided behaviors in the transgenic 3xTg-AD female mouse model of Alzheimer׳s disease.
Volume: 1572
Pages: 18-25
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Publication
31827783 | J:285624
 
First Author: Lauritzen I
Year: 2019
Journal: Transl Neurodegener
Title: Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models.
Volume: 8
Pages: 35
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Publication
20092557 | J:158364
First Author: Härtig W
Year: 2010
Journal: Eur J Neurosci
Title: In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
Volume: 31
Issue: 1
Pages: 99-109
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Publication
38670478 | J:348554
 
First Author: Xie Y
Year: 2024
Journal: Brain Res
Title: The synergistic effect of curcumin and mitoquinol mesylate on cognitive impairment and the neuropathology of Alzheimer's disease.
Volume: 1837
Pages: 148959
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Publication
35799540 | J:348307
First Author: Yan F
Year: 2023
Journal: Neural Regen Res
Title: Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.
Volume: 18
Issue: 1
Pages: 183-188
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Publication
19641109 | J:151323
First Author: Chakroborty S
Year: 2009
Journal: J Neurosci
Title: Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice.
Volume: 29
Issue: 30
Pages: 9458-70
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22442077 | J:260030
First Author: Cotella D
Year: 2012
Journal: J Neurosci
Title: Toxic role of K+ channel oxidation in mammalian brain.
Volume: 32
Issue: 12
Pages: 4133-44
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Publication
30411846 | J:273257
First Author: Kim HJ
Year: 2019
Journal: Aging Cell
Title: Carbon monoxide attenuates amyloidogenesis via down-regulation of NF-κB-mediated BACE1 gene expression.
Volume: 18
Issue: 1
Pages: e12864
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Publication
23595620 | J:284815
First Author: Hokama M
Year: 2014
Journal: Cereb Cortex
Title: Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study.
Volume: 24
Issue: 9
Pages: 2476-88
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Publication
32222473 | J:299295
 
First Author: Tripathy D
Year: 2020
Journal: Neurobiol Dis
Title: Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aβ1-42-mediated toxicity.
Volume: 140
Pages: 104849
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Publication
22961199 | J:212512
First Author: Yamamoto S
Year: 2013
Journal: Transgenic Res
Title: Generation of gene-targeted mice using embryonic stem cells derived from a transgenic mouse model of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 537-47
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Publication
38301041 | J:347915
First Author: Park HH
Year: 2024
Journal: Aging (Albany NY)
Title: GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects.
Volume: 16
Issue: 3
Pages: 1983-2004
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Publication
36889377 | J:335713
 
First Author: Wei R
Year: 2023
Journal: Neurosci Lett
Title: Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease.
Volume: 802
Pages: 137166
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Publication
36303870 | J:331557
 
First Author: Farkas S
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Ovariectomy-induced hormone deprivation aggravates Aβ(1-42) deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer's disease.
Volume: 13
Pages: 985424
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Publication
29925037 | J:266088
 
First Author: Christensen A
Year: 2018
Journal: Neurosci Lett
Title: TSPO ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice.
Volume: 683
Pages: 7-12
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Publication
31842924 | J:292127
First Author: Sekhar GN
Year: 2019
Journal: Fluids Barriers CNS
Title: Region-specific blood-brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 38
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Publication
38565895 | J:347933
First Author: Hamilton LK
Year: 2024
Journal: Sci Rep
Title: Central inhibition of stearoyl-CoA desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer's disease mouse model.
Volume: 14
Issue: 1
Pages: 7742
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Publication
21855175 | J:188192
First Author: Rothman SM
Year: 2012
Journal: Neurobiol Aging
Title: 3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress.
Volume: 33
Issue: 4
Pages: 830.e1-12
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Publication
30412792 | J:276886
First Author: Pinho TS
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
Volume: 1865
Issue: 8
Pages: 2048-2059
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Publication
25140151 | J:289577
 
First Author: Cantanelli P
Year: 2014
Journal: Front Aging Neurosci
Title: Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice.
Volume: 6
Pages: 200
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Publication
26635562 | J:289580
 
First Author: Huang HJ
Year: 2015
Journal: Front Behav Neurosci
Title: Administration of NaHS Attenuates Footshock-Induced Pathologies and Emotional and Cognitive Dysfunction in Triple Transgenic Alzheimer's Mice.
Volume: 9
Pages: 312
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Publication
27255814 | J:234996
 
First Author: Vandal M
Year: 2016
Journal: Neurobiol Aging
Title: Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease.
Volume: 43
Pages: 47-57
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Publication
33994914 | J:311285
 
First Author: Bello-Medina PC
Year: 2021
Journal: Front Neurosci
Title: Spatial Memory and Gut Microbiota Alterations Are Already Present in Early Adulthood in a Pre-clinical Transgenic Model of Alzheimer's Disease.
Volume: 15
Pages: 595583
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21294162 | J:168831
First Author: Desai MK
Year: 2011
Journal: Glia
Title: An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction.
Volume: 59
Issue: 4
Pages: 627-40
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Publication
18603329 | J:159591
First Author: Nakashima AS
Year: 2010
Journal: Neurobiol Aging
Title: Experience-dependent regulation of vesicular zinc in male and female 3xTg-AD mice.
Volume: 31
Issue: 4
Pages: 605-13
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Publication
28575011 | J:247319
First Author: Christensen A
Year: 2017
Journal: PLoS One
Title: Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice.
Volume: 12
Issue: 6
Pages: e0178490
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Publication
33634105 | J:314045
 
First Author: Chen C
Year: 2020
Journal: Front Cell Dev Biol
Title: Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease.
Volume: 8
Pages: 624339
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Publication
26362250 | J:226489
First Author: Smith PY
Year: 2015
Journal: Hum Mol Genet
Title: miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Volume: 24
Issue: 23
Pages: 6721-35
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Publication
33335468 | J:311316
 
First Author: Rocha NKR
Year: 2020
Journal: Front Neurosci
Title: Neuronal-Glial Interaction in a Triple-Transgenic Mouse Model of Alzheimer's Disease: Gene Ontology and Lithium Pathways.
Volume: 14
Pages: 579984
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Publication
25446741 | J:223868
 
First Author: Cañete T
Year: 2015
Journal: Behav Brain Res
Title: Cognitive and emotional alterations in young Alzheimer's disease (3xTgAD) mice: effects of neonatal handling stimulation and sexual dimorphism.
Volume: 281
Pages: 156-71
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Publication
31276749 | J:291314
 
First Author: Gali CC
Year: 2019
Journal: Mol Cell Neurosci
Title: Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Volume: 99
Pages: 103390
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Publication
31521745 | J:291312
 
First Author: Young ML
Year: 2019
Journal: Mol Cell Neurosci
Title: The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice.
Volume: 101
Pages: 103409
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Publication
29331876 | J:262423
 
First Author: Bignante EA
Year: 2018
Journal: Neurobiol Aging
Title: APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models.
Volume: 64
Pages: 44-57
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Publication
34731612 | J:334268
First Author: Salvan P
Year: 2021
Journal: Cell Rep
Title: Frequency modulation of entorhinal cortex neuronal activity drives distinct frequency-dependent states of brain-wide dynamics.
Volume: 37
Issue: 5
Pages: 109954
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Publication
16192374 | J:101347
First Author: Kitazawa M
Year: 2005
Journal: J Neurosci
Title: Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.
Volume: 25
Issue: 39
Pages: 8843-53
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Publication
21918687 | J:176128
First Author: Chen S
Year: 2011
Journal: PLoS One
Title: Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
Volume: 6
Issue: 8
Pages: e24293
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Publication
23500896 | J:197528
 
First Author: Davis KE
Year: 2013
Journal: Behav Brain Res
Title: Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice.
Volume: 254
Pages: 73-82
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Publication
32816243 | J:311336
First Author: Ochi S
Year: 2020
Journal: Mol Neurobiol
Title: Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice.
Volume: 57
Issue: 12
Pages: 4941-4951
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Publication
33621639 | J:311340
 
First Author: Santos-Gil DF
Year: 2021
Journal: Neurosci Lett
Title: Retinoid X receptor activation promotes re-myelination in a very old triple transgenic mouse model of Alzheimer's disease.
Volume: 750
Pages: 135764
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Publication
19605645 | J:151572
First Author: Ma QL
Year: 2009
Journal: J Neurosci
Title: Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.
Volume: 29
Issue: 28
Pages: 9078-89
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Publication
31596896 | J:280799
First Author: Muñoz-Cabrera JM
Year: 2019
Journal: PLoS One
Title: Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease.
Volume: 14
Issue: 10
Pages: e0223578
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Publication
20798886 | J:284909
   
First Author: Oh KJ
Year: 2010
Journal: Int J Alzheimers Dis
Title: Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.
Volume: 2010
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Publication
34483889 | J:311359
 
First Author: Winslow W
Year: 2021
Journal: Front Aging Neurosci
Title: IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer's Disease Associated With Brain Weight.
Volume: 13
Pages: 720214
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Publication
28261055 | J:311363
 
First Author: Gardenal E
Year: 2017
Journal: Front Neurosci
Title: Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 81
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Publication
27634771 | J:238217
 
First Author: Härtig W
Year: 2016
Journal: Neuroscience
Title: Abolished perineuronal nets and altered parvalbumin-immunoreactivity in the nucleus reticularis thalami of wildtype and 3xTg mice after experimental stroke.
Volume: 337
Pages: 66-87
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23486975 | J:196598
First Author: Ghosh S
Year: 2013
Journal: J Neurosci
Title: Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
Volume: 33
Issue: 11
Pages: 5053-64
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Publication
35053244 | J:324105
 
First Author: Meinicke A
Year: 2022
Journal: Biomolecules
Title: Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content.
Volume: 12
Issue: 1
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Publication
24726470 | J:214857
First Author: Han P
Year: 2014
Journal: Neurobiol Aging
Title: Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity.
Volume: 35
Issue: 9
Pages: 2064-71
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Publication
23827221 | J:201677
 
First Author: Rodríguez JJ
Year: 2013
Journal: Neurosci Lett
Title: Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease.
Volume: 552
Pages: 129-34
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Publication
30718609 | J:275242
First Author: Stimmell AC
Year: 2019
Journal: Sci Rep
Title: Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 9
Issue: 1
Pages: 1311
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Publication
33753066 | J:306942
 
First Author: Pairojana T
Year: 2021
Journal: Brain Res
Title: Age and gender differences for the behavioral phenotypes of 3xTg alzheimer's disease mice.
Volume: 1762
Pages: 147437
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21383850 | J:171054
First Author: Arsenault D
Year: 2011
Journal: PLoS One
Title: DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice.
Volume: 6
Issue: 2
Pages: e17397
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Publication
34276338 | J:308266
 
First Author: Ryou MG
Year: 2021
Journal: Front Aging Neurosci
Title: Intermittent Hypoxia Training Prevents Deficient Learning-Memory Behavior in Mice Modeling Alzheimer's Disease: A Pilot Study.
Volume: 13
Pages: 674688
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Publication
29213096 | J:287381
First Author: Rajamohamedsait H
Year: 2017
Journal: Sci Rep
Title: Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.
Volume: 7
Issue: 1
Pages: 17034
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Publication
30478329 | J:269715
First Author: Baek H
Year: 2018
Journal: Sci Rep
Title: Bee venom phospholipase A2 ameliorates Alzheimer's disease pathology in Aβ vaccination treatment without inducing neuro-inflammation in a 3xTg-AD mouse model.
Volume: 8
Issue: 1
Pages: 17369
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Publication
16687509 | J:108684
First Author: Stutzmann GE
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