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Search results 201 to 300 out of 1527 for Mecp2

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Type Details Score
Publication
29438740 | J:272679
 
First Author: Gulmez Karaca K
Year: 2018
Journal: Neurobiol Learn Mem
Title: Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation.
Volume: 149
Pages: 84-97
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23558747 | J:200652
First Author: Stuss DP
Year: 2013
Journal: Nucleic Acids Res
Title: Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain.
Volume: 41
Issue: 9
Pages: 4888-900
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Publication
25878291 | J:221674
First Author: Su SH
Year: 2015
Journal: J Neurosci
Title: MeCP2 in the rostral striatum maintains local dopamine content critical for psychomotor control.
Volume: 35
Issue: 15
Pages: 6209-20
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Publication
17050729 | J:113437
First Author: Wang H
Year: 2006
Journal: J Neurosci
Title: Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice.
Volume: 26
Issue: 42
Pages: 10911-5
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Publication
17532643 | J:134828
First Author: Smrt RD
Year: 2007
Journal: Neurobiol Dis
Title: Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons.
Volume: 27
Issue: 1
Pages: 77-89
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Publication
21307327 | J:323732
First Author: Calfa G
Year: 2011
Journal: J Neurophysiol
Title: Network hyperexcitability in hippocampal slices from Mecp2 mutant mice revealed by voltage-sensitive dye imaging.
Volume: 105
Issue: 4
Pages: 1768-84
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Publication
25662825 | J:241047
First Author: Sceniak MP
Year: 2016
Journal: Cereb Cortex
Title: Mechanisms of Functional Hypoconnectivity in the Medial Prefrontal Cortex of Mecp2 Null Mice.
Volume: 26
Issue: 5
Pages: 1938-1956
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Publication
32469049 | J:296009
First Author: Merritt JK
Year: 2020
Journal: Hum Mol Genet
Title: Pharmacological read-through of R294X Mecp2 in a novel mouse model of Rett syndrome.
Volume: 29
Issue: 15
Pages: 2461-2470
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Publication
19225110 | J:147157
First Author: Tao J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.
Volume: 106
Issue: 12
Pages: 4882-7
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Publication
29698767 | J:323619
 
First Author: Zhong X
Year: 2019
Journal: Neurobiol Learn Mem
Title: Regulation of neural differentiation, synaptic scaling and animal behavior by MeCP2 phophorylation.
Volume: 165
Pages: 106859
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Publication
20172507 | J:283223
First Author: Lonetti G
Year: 2010
Journal: Biol Psychiatry
Title: Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.
Volume: 67
Issue: 7
Pages: 657-65
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Publication
24352790 | J:209069
First Author: Yasui DH
Year: 2014
Journal: Hum Mol Genet
Title: Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome.
Volume: 23
Issue: 9
Pages: 2447-58
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Publication
30137367 | J:266982
First Author: Vogel Ciernia A
Year: 2018
Journal: Hum Mol Genet
Title: MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome.
Volume: 27
Issue: 23
Pages: 4077-4093
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Publication
34040112 | J:318054
First Author: Zalosnik MI
Year: 2021
Journal: Sci Rep
Title: MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge.
Volume: 11
Issue: 1
Pages: 10997
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Publication
26066729 | J:321100
 
First Author: Pearson BL
Year: 2015
Journal: Physiol Behav
Title: Applying the ethoexperimental approach to neurodevelopmental syndrome research reveals exaggerated defensive behavior in Mecp2 mutant mice.
Volume: 146
Pages: 98-104
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Publication
37890975 | J:343257
First Author: Zhou J
Year: 2023
Journal: Genes Dev
Title: A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels.
Volume: 37
Issue: 19-20
Pages: 883-900
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11809720 | J:74625
First Author: Shahbazian MD
Year: 2002
Journal: Hum Mol Genet
Title: Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation.
Volume: 11
Issue: 2
Pages: 115-24
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Publication
23684790 | J:198917
First Author: Bodda C
Year: 2013
Journal: Am J Pathol
Title: Mild overexpression of Mecp2 in mice causes a higher susceptibility toward seizures.
Volume: 183
Issue: 1
Pages: 195-210
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Publication
22923521 | J:199746
First Author: Casas-Delucchi CS
Year: 2012
Journal: Nucleic Acids Res
Title: Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization.
Volume: 40
Issue: 22
Pages: e176
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Publication
32015323 | J:302400
First Author: Lu Z
Year: 2020
Journal: Cell Death Dis
Title: Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice.
Volume: 11
Issue: 2
Pages: 85
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Publication
30105297 | J:266700
 
First Author: Ash RT
Year: 2018
Journal: eNeuro
Title: Increased Axonal Bouton Stability during Learning in the Mouse Model of MECP2 Duplication Syndrome.
Volume: 5
Issue: 3
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Publication
28173151 | J:238655
First Author: Ross PD
Year: 2016
Journal: Hum Mol Genet
Title: Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes.
Volume: 25
Issue: 20
Pages: 4389-4404
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Publication
29074463 | J:256748
First Author: Xu M
Year: 2018
Journal: Biochim Biophys Acta
Title: Disruption of AT-hook 1 domain in MeCP2 protein caused behavioral abnormality in mice.
Volume: 1864
Issue: 2
Pages: 347-358
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19628041 | J:154226
First Author: Degano AL
Year: 2009
Journal: Mol Cell Neurosci
Title: MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function.
Volume: 42
Issue: 3
Pages: 243-54
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26590342 | J:228740
First Author: Ito-Ishida A
Year: 2015
Journal: Neuron
Title: Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes.
Volume: 88
Issue: 4
Pages: 651-8
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Publication
28143937 | J:240927
First Author: Sripathy S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.
Volume: 114
Issue: 7
Pages: 1619-1624
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Publication
35154497 | J:323675
First Author: Lee S
Year: 2022
Journal: Theranostics
Title: Dysfunction of striatal MeCP2 is associated with cognitive decline in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 3
Pages: 1404-1418
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Publication
23948639 | J:201760
 
First Author: Zhao YT
Year: 2013
Journal: Neurobiol Dis
Title: Loss of MeCP2 function is associated with distinct gene expression changes in the striatum.
Volume: 59
Pages: 257-66
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25209930 | J:318287
First Author: Calfa G
Year: 2015
Journal: Hippocampus
Title: Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice.
Volume: 25
Issue: 2
Pages: 159-68
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Publication
24523563 | J:206934
First Author: Zhang W
Year: 2014
Journal: J Neurosci
Title: Loss of MeCP2 from forebrain excitatory neurons leads to cortical hyperexcitation and seizures.
Volume: 34
Issue: 7
Pages: 2754-63
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Publication
26195221 | J:248974
First Author: Mayer SC
Year: 2015
Journal: Circ Res
Title: Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure.
Volume: 117
Issue: 7
Pages: 622-33
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Publication
28093257 | J:249236
First Author: Zhou H
Year: 2017
Journal: Behav Brain Res
Title: Selective preservation of cholinergic MeCP2 rescues specific Rett-syndrome-like phenotypes in MeCP2stop mice.
Volume: 322
Issue: Pt A
Pages: 51-59
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Publication
31974426 | J:291619
First Author: Hsu WL
Year: 2020
Journal: Sci Rep
Title: Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome.
Volume: 10
Issue: 1
Pages: 1074
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16446138 | J:106973
First Author: Chang Q
Year: 2006
Journal: Neuron
Title: The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression.
Volume: 49
Issue: 3
Pages: 341-8
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Publication
27668390 | J:238210
First Author: Mahgoub M
Year: 2016
Journal: Nat Neurosci
Title: MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors.
Volume: 19
Issue: 11
Pages: 1506-1512
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Publication
25297674 | J:225339
 
First Author: He LJ
Year: 2014
Journal: Nat Commun
Title: Conditional deletion of Mecp2 in parvalbumin-expressing GABAergic cells results in the absence of critical period plasticity.
Volume: 5
Pages: 5036
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22119903 | J:181311
First Author: Goffin D
Year: 2011
Journal: Nat Neurosci
Title: Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses.
Volume: 15
Issue: 2
Pages: 274-83
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27103432 | J:278033
First Author: Zhang Y
Year: 2016
Journal: Cell Res
Title: Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus.
Volume: 26
Issue: 6
Pages: 728-42
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Publication
24958888 | J:212167
First Author: Li C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation.
Volume: 111
Issue: 27
Pages: E2807-16
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Publication
25885346 | J:319106
 
First Author: Zhang R
Year: 2015
Journal: Mol Pain
Title: MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway.
Volume: 11
Pages: 19
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Publication
35148843 | J:326514
First Author: Mira-Bontenbal H
Year: 2022
Journal: Stem Cell Reports
Title: Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells.
Volume: 17
Issue: 3
Pages: 693-706
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Publication
24009314 | J:204519
First Author: Lang M
Year: 2014
Journal: Hum Mol Genet
Title: Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation.
Volume: 23
Issue: 2
Pages: 303-18
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Publication
25392929 | J:225153
First Author: Gadalla KK
Year: 2014
Journal: PLoS One
Title: Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits.
Volume: 9
Issue: 11
Pages: e112889
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Publication
15780747 | J:97538
First Author: Pelka GJ
Year: 2005
Journal: Genomics
Title: Distinct expression profiles of Mecp2 transcripts with different lengths of 3'UTR in the brain and visceral organs during mouse development.
Volume: 85
Issue: 4
Pages: 441-52
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Publication
29562294 | J:323668
First Author: Zhang W
Year: 2018
Journal: J Mol Cell Biol
Title: MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation.
Volume: 10
Issue: 6
Pages: 515-526
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Publication
16682435 | J:112064
First Author: Peddada S
Year: 2006
Journal: Hum Mol Genet
Title: Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome.
Volume: 15
Issue: 12
Pages: 2003-14
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Publication
34010654 | J:306623
First Author: Nakashima H
Year: 2021
Journal: Cell Rep
Title: MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling.
Volume: 35
Issue: 7
Pages: 109124
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Publication
24619648 | J:259192
First Author: Jiang S
Year: 2014
Journal: Sci Signal
Title: MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5.
Volume: 7
Issue: 316
Pages: ra25
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Publication
22919518 | J:315805
 
First Author: Chapleau CA
Year: 2012
Journal: Neural Plast
Title: Hippocampal CA1 pyramidal neurons of Mecp2 mutant mice show a dendritic spine phenotype only in the presymptomatic stage.
Volume: 2012
Pages: 976164
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26908602 | J:233024
First Author: Du F
Year: 2016
Journal: Hum Mol Genet
Title: Acute and crucial requirement for MeCP2 function upon transition from early to late adult stages of brain maturation.
Volume: 25
Issue: 9
Pages: 1690-702
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Publication
24639629 | J:323687
 
First Author: Xu X
Year: 2014
Journal: Front Cell Neurosci
Title: A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome.
Volume: 8
Pages: 68
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28139724 | J:275159
 
First Author: Chen Z
Year: 2017
Journal: Sci Rep
Title: Accumulated quiescent neural stem cells in adult hippocampus of the mouse model for the MECP2 duplication syndrome.
Volume: 7
Pages: 41701
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24990380 | J:323661
First Author: Kernohan KD
Year: 2014
Journal: Nucleic Acids Res
Title: Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping.
Volume: 42
Issue: 13
Pages: 8356-68
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16467389 | J:137513
First Author: Pelka GJ
Year: 2006
Journal: Brain
Title: Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice.
Volume: 129
Issue: Pt 4
Pages: 887-98
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19167498 | J:147302
First Author: Belichenko NP
Year: 2009
Journal: Neurobiol Dis
Title: Evidence for both neuronal cell autonomous and nonautonomous effects of methyl-CpG-binding protein 2 in the cerebral cortex of female mice with Mecp2 mutation.
Volume: 34
Issue: 1
Pages: 71-7
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26261347 | J:226639
First Author: Krishnan K
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex.
Volume: 112
Issue: 34
Pages: E4782-91
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20025874 | J:158027
First Author: Kishi N
Year: 2010
Journal: Exp Neurol
Title: MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons.
Volume: 222
Issue: 1
Pages: 51-8
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25941473 | J:242667
 
First Author: Rietveld L
Year: 2015
Journal: Front Cell Neurosci
Title: Genotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice.
Volume: 9
Pages: 145
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20163734 | J:171410
 
First Author: Jentarra GM
Year: 2010
Journal: BMC Neurosci
Title: Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation.
Volume: 11
Pages: 19
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29636529 | J:263039
First Author: Philippe TJ
Year: 2018
Journal: Sci Rep
Title: Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes.
Volume: 8
Issue: 1
Pages: 5788
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28367114 | J:284907
 
First Author: Maphis NM
Year: 2017
Journal: Front Mol Neurosci
Title: Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.
Volume: 10
Pages: 69
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27328321 | J:234272
   
First Author: Ure K
Year: 2016
Journal: Elife
Title: Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome.
Volume: 5
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20159591 | J:158584
First Author: Kernohan KD
Year: 2010
Journal: Dev Cell
Title: ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain.
Volume: 18
Issue: 2
Pages: 191-202
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- | J:185639
     
First Author: International Rett Syndrome Foundation
Year: 2012
Journal: MGI Direct Data Submission
Title: A targeted allele of Mecp2
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37940561 | J:344381
 
First Author: Bogatova D
Year: 2024
Journal: eNeuro
Title: Tug-of-Peace: Visual Rivalry and Atypical Visual Motion Processing in MECP2 Duplication Syndrome of Autism.
Volume: 11
Issue: 1
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23750231 | J:204260
First Author: Larimore J
Year: 2013
Journal: PLoS One
Title: MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.
Volume: 8
Issue: 6
Pages: e65069
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33551790 | J:323671
 
First Author: Li P
Year: 2020
Journal: Front Aging Neurosci
Title: AD7c-NTP Impairs Adult Striatal Neurogenesis by Affecting the Biological Function of MeCP2 in APP/PSl Transgenic Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 616614
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23077217 | J:191128
First Author: Lang M
Year: 2013
Journal: Hum Mol Genet
Title: Selective preservation of MeCP2 in catecholaminergic cells is sufficient to improve the behavioral phenotype of male and female Mecp2-deficient mice.
Volume: 22
Issue: 2
Pages: 358-71
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15519245 | J:94370
First Author: Kishi N
Year: 2004
Journal: Mol Cell Neurosci
Title: MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions.
Volume: 27
Issue: 3
Pages: 306-21
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19602036 | J:306579
First Author: Hwang CK
Year: 2009
Journal: J Cell Mol Med
Title: Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor.
Volume: 13
Issue: 9B
Pages: 3591-615
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27499081 | J:253353
First Author: Lu H
Year: 2016
Journal: Neuron
Title: Loss and Gain of MeCP2 Cause Similar Hippocampal Circuit Dysfunction that Is Rescued by Deep Brain Stimulation in a Rett Syndrome Mouse Model.
Volume: 91
Issue: 4
Pages: 739-747
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22815516 | J:186548
First Author: Nguyen MV
Year: 2012
Journal: J Neurosci
Title: MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain.
Volume: 32
Issue: 29
Pages: 10021-34
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31299345 | J:282985
 
First Author: Asgarihafshejani A
Year: 2019
Journal: Neuroscience
Title: Cell-Genotype Specific Effects of Mecp2 Mutation on Spontaneous and Nicotinic Acetylcholine Receptor-Evoked Currents in Medial Prefrontal Cortical Pyramidal Neurons in Female Rett Model Mice.
Volume: 414
Pages: 141-153
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22412847 | J:186936
First Author: Stuss DP
Year: 2012
Journal: PLoS One
Title: MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice.
Volume: 7
Issue: 3
Pages: e31896
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18334558 | J:138474
First Author: Kumar A
Year: 2008
Journal: J Cell Sci
Title: Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo.
Volume: 121
Issue: Pt 7
Pages: 1128-37
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15917271 | J:99792
First Author: Mari F
Year: 2005
Journal: Hum Mol Genet
Title: CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome.
Volume: 14
Issue: 14
Pages: 1935-46
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30619462 | J:310911
 
First Author: Olson CO
Year: 2018
Journal: Front Genet
Title: MECP2 Mutation Interrupts Nucleolin-mTOR-P70S6K Signaling in Rett Syndrome Patients.
Volume: 9
Pages: 635
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32207685 | J:291063
   
First Author: Luoni M
Year: 2020
Journal: Elife
Title: Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome.
Volume: 9
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31366578 | J:279768
 
First Author: Tang X
Year: 2019
Journal: Sci Transl Med
Title: Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice.
Volume: 11
Issue: 503
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32393583 | J:289443
 
First Author: Ribeiro MC
Year: 2020
Journal: eNeuro
Title: Vitamin D Supplementation Rescues Aberrant NF-κB Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in Mecp2 Mutant Mice.
Volume: 7
Issue: 3
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23035095 | J:190929
First Author: Kron M
Year: 2012
Journal: J Neurosci
Title: Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.
Volume: 32
Issue: 40
Pages: 13860-72
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35242007 | J:323677
 
First Author: Albizzati E
Year: 2022
Journal: Front Neurosci
Title: Identification of Region-Specific Cytoskeletal and Molecular Alterations in Astrocytes of Mecp2 Deficient Animals.
Volume: 16
Pages: 823060
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33658357 | J:304422
 
First Author: Shao Y
Year: 2021
Journal: Sci Transl Med
Title: Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome.
Volume: 13
Issue: 583
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Publication
30012595 | J:267746
First Author: Przanowski P
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice.
Volume: 115
Issue: 31
Pages: 7991-7996
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GXD Expression
GXD Expression
   
Probe: MGI:7449282
Assay Type: RT-PCR
Annotation Date: 2023-04-04
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7450708
Age: postnatal adult
Image: 5
Specimen Label: Mecp2 -/y
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7449281
Assay Type: RT-PCR
Annotation Date: 2023-04-04
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7450709
Age: postnatal adult
Image: 5
Specimen Label: Mecp2 -/y
Detected: true
Specimen Num: 2
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Protein Domain
IPR017353 | Me_CpG-bd_MeCP2
Type: Family
Description: Methyl-CpG-binding protein 2 (Mecp2) binds specifically to methylated DNA and represses transcription through the recruitment of chromatin remodeling complexes containing histone deacetylase activities [, ]. It is a multi-functional protein whose function depends on its protein partners and post-translational modifications []. Mecp2 is required for proper mitotic spindle organisation []and affects proliferation and apoptosis []. Mutations in MeCP2 gene cause an X-linked neurodevelopmental disease known as Rett syndrome [].
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Publication
31562178 | J:288426
 
First Author: Ballinger EC
Year: 2019
Journal: eNeuro
Title: Mecp2 Deletion from Cholinergic Neurons Selectively Impairs Recognition Memory and Disrupts Cholinergic Modulation of the Perirhinal Cortex.
Volume: 6
Issue: 6
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Publication
33494858 | J:300830
   
First Author: Achilly NP
Year: 2021
Journal: Elife
Title: Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice.
Volume: 10
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Publication
30255129 | J:266776
 
First Author: Morello N
Year: 2018
Journal: eNeuro
Title: Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.
Volume: 5
Issue: 5
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Protein
Q9Z2D6
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
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Publication
9620779 | -
First Author: Jones PL
Year: 1998
Journal: Nat Genet
Title: Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription.
Volume: 19
Issue: 2
Pages: 187-91
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Publication
9774669 | J:50520
First Author: Hendrich B
Year: 1998
Journal: Mol Cell Biol
Title: Identification and characterization of a family of mammalian methyl-CpG binding proteins.
Volume: 18
Issue: 11
Pages: 6538-47
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Publication
22186023 | J:181897
First Author: Braun S
Year: 2012
Journal: Hum Mol Genet
Title: Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome.
Volume: 21
Issue: 8
Pages: 1673-80
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Regulatory Region
MGI:7356632 | Rr296
Type: silencer
Organism: mouse, laboratory
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Publication
20138994 | J:159917
First Author: Wood L
Year: 2010
Journal: Neurobiol Dis
Title: Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in a mutant mouse model of Rett syndrome.
Volume: 38
Issue: 2
Pages: 281-7
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Publication
20045053 | J:159940
First Author: D'Cruz JA
Year: 2010
Journal: Neurobiol Dis
Title: Alterations of cortical and hippocampal EEG activity in MeCP2-deficient mice.
Volume: 38
Issue: 1
Pages: 8-16
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Publication
20634955 | J:163111
First Author: Kerr B
Year: 2010
Journal: PLoS One
Title: Unconventional transcriptional response to environmental enrichment in a mouse model of Rett syndrome.
Volume: 5
Issue: 7
Pages: e11534
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Publication
16439027 | J:106418
First Author: Jugloff DG
Year: 2006
Journal: J Neurosci Methods
Title: Breeding and maintenance of an Mecp2-deficient mouse model of Rett syndrome.
Volume: 154
Issue: 1-2
Pages: 89-95
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Publication
21482354 | J:174711
First Author: Noutel J
Year: 2011
Journal: Neuron
Title: Experience-dependent retinogeniculate synapse remodeling is abnormal in MeCP2-deficient mice.
Volume: 70
Issue: 1
Pages: 35-42
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