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Search results 1 to 100 out of 142 for Fen1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chung L
Year: 2015
Journal: Oncogene
Title: The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.
Volume: 34
Issue: 7
Pages: 902-11
Publication
First Author: Zheng L
Year: 2007
Journal: Nat Med
Title: Fen1 mutations result in autoimmunity, chronic inflammation and cancers.
Volume: 13
Issue: 7
Pages: 812-9
GXD Expression    
Probe: MGI:3621638
Assay Type: RNA in situ
Annotation Date: 2006-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3621797
Age: embryonic day 12.5
Specimen Label: 5A Fen1 E12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3621638
Assay Type: RNA in situ
Annotation Date: 2006-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3621797
Age: embryonic day 14.5
Note: Expression in this specimen was lower than the E12.5 specimen.
Specimen Label: 5A Fen1 E14
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3621638
Assay Type: RNA in situ
Annotation Date: 2006-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3621797
Age: embryonic day 16.5
Note: Expression in this specimen was lower than the E12.5 specimen.
Specimen Label: 5A Fen1 E16
Detected: true
Specimen Num: 3
Publication
First Author: Kucherlapati M
Year: 2007
Journal: Oncogene
Title: Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.
Volume: 26
Issue: 43
Pages: 6297-306
Publication
First Author: Kleppa L
Year: 2012
Journal: Nucleic Acids Res
Title: Kinetics of endogenous mouse FEN1 in base excision repair.
Volume: 40
Issue: 18
Pages: 9044-59
Publication
First Author: Larsen E
Year: 2008
Journal: Cancer Res
Title: Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants.
Volume: 68
Issue: 12
Pages: 4571-9
Publication
First Author: Wu Z
Year: 2012
Journal: Mutat Res
Title: High risk of benzo[α]pyrene-induced lung cancer in E160D FEN1 mutant mice.
Volume: 731
Issue: 1-2
Pages: 85-91
Publication
First Author: Zheng L
Year: 2011
Journal: Cell Res
Title: Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.
Volume: 21
Issue: 7
Pages: 1052-67
Publication
First Author: Larsen E
Year: 2003
Journal: Mol Cell Biol
Title: Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage.
Volume: 23
Issue: 15
Pages: 5346-53
Publication
First Author: Christmann M
Year: 2005
Journal: Oncogene
Title: Fen1 is induced p53 dependently and involved in the recovery from UV-light-induced replication inhibition.
Volume: 24
Issue: 56
Pages: 8304-13
Publication
First Author: van den Broek WJ
Year: 2006
Journal: FEBS Lett
Title: Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1.
Volume: 580
Issue: 22
Pages: 5208-14
Publication
First Author: Zhou L
Year: 2017
Journal: FASEB J
Title: Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
Volume: 31
Issue: 1
Pages: 132-147
Publication
First Author: Cheng IC
Year: 2016
Journal: PLoS Biol
Title: Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1.
Volume: 14
Issue: 1
Pages: e1002349
Publication
First Author: Liu S
Year: 2015
Journal: EMBO J
Title: Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex.
Volume: 34
Issue: 13
Pages: 1829-43
Publication
First Author: Hiraoka LR
Year: 1995
Journal: Genomics
Title: Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human.
Volume: 25
Issue: 1
Pages: 220-5
Publication
First Author: Nardi I
Year: 2018
Journal: Int J Cancer
Title: Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3.
Volume: 143
Issue: 10
Pages: 2470-2478
Publication
First Author: Kucherlapati M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.
Volume: 99
Issue: 15
Pages: 9924-9
Publication
First Author: Emoto M
Year: 2005
Journal: Gene
Title: Structure and transcription promoter activity of mouse flap endonuclease 1 gene: alternative splicing and bidirectional promoter.
Volume: 357
Issue: 1
Pages: 47-54
Publication
First Author: Zheng L
Year: 2007
Journal: Mol Cell Biol
Title: Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice.
Volume: 27
Issue: 8
Pages: 3176-86
Publication
First Author: Xu M
Year: 2013
Journal: Nucleic Acids Res
Title: Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1.
Volume: 41
Issue: 3
Pages: 1684-97
Publication
First Author: Goula AV
Year: 2009
Journal: PLoS Genet
Title: Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
Volume: 5
Issue: 12
Pages: e1000749
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Harrington JJ
Year: 1994
Journal: Genes Dev
Title: Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
Volume: 8
Issue: 11
Pages: 1344-55
Publication
First Author: Møllersen L
Year: 2010
Journal: PLoS Genet
Title: Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice.
Volume: 6
Issue: 12
Pages: e1001242
Publication
First Author: Sun H
Year: 2021
Journal: Science
Title: Error-prone, stress-induced 3' flap-based Okazaki fragment maturation supports cell survival.
Volume: 374
Issue: 6572
Pages: 1252-1258
Publication  
First Author: Zheng L
Year: 2017
Journal: Mol Cell Biol
Title: Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-κB Survival Pathways in Cancer Cells.
Volume: 37
Issue: 15
Publication
First Author: Zheng L
Year: 2002
Journal: Biochemistry
Title: Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities.
Volume: 41
Issue: 32
Pages: 10323-31
Publication
First Author: Harrington JJ
Year: 1994
Journal: EMBO J
Title: The characterization of a mammalian DNA structure-specific endonuclease.
Volume: 13
Issue: 5
Pages: 1235-46
Publication
First Author: Spiro C
Year: 2003
Journal: Mol Cell Biol
Title: Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability.
Volume: 23
Issue: 17
Pages: 6063-74
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3604546
Age: embryonic day 7.0
Specimen Label: 7 day
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3604546
Age: embryonic day 11.0
Specimen Label: 11 day
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3604546
Age: embryonic day 15.0
Specimen Label: 15 day
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3604546
Age: embryonic day 17.0
Specimen Label: 17 day
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3604532
Assay Type: RT-PCR
Annotation Date: 2005-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3604546
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1060932
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516884
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Szczesny B
Year: 2014
Journal: Nucleic Acids Res
Title: Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Volume: 42
Issue: 21
Pages: 13161-73
Publication  
First Author: Kafer GR
Year: 2020
Journal: Front Cell Dev Biol
Title: A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis.
Volume: 8
Pages: 416
Publication
First Author: Katyal S
Year: 2014
Journal: Nat Neurosci
Title: Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Volume: 17
Issue: 6
Pages: 813-21
Publication
First Author: Moon S
Year: 2018
Journal: Cell Death Dis
Title: Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Volume: 9
Issue: 11
Pages: 1118
Publication
First Author: Ajioka I
Year: 2006
Journal: Eur J Neurosci
Title: Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.
Volume: 23
Issue: 2
Pages: 296-308
Publication        
First Author: UniProt curators
Year: 2014
Title: Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees