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Search results 1101 to 1154 out of 1154 for Tbx5

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0.022s

Type

Details

Score

Allele

Rr108735<em1Axvi> | MGI:7489687

Name:	regulatory region 108735; endonuclease-mediated mutation 1, Axel Visel
Allele Type:	Endonuclease-mediated
Attribute String:	Modified regulatory region

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Allele

Del(5Rr426-Rr108735)1Axvi | MGI:7489863

Name:	deletion, Chr 5, Axel Visel 1
Allele Type:	Endonuclease-mediated
Attribute String:	Modified regulatory region

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HT Experiment

GSE237090 | Bulk RNA seq of P0 aCMs and P28 aCMs


Experiment Type:	RNA-Seq
Study Type:	Baseline
Source:	GEO

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Publication

17196583 | J:119193

First Author:	Wakahara T
Year:	2007
Journal:	Dev Biol
Title:	Fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish.
Volume:	303
Issue:	2
Pages:	527-35

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Allele

Rr51<em1Axvi> | MGI:7489587

Name:	regulatory region 51; endonuclease-mediated mutation 1, Axel Visel
Allele Type:	Endonuclease-mediated
Attribute String:	Modified regulatory region

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Allele

Rr55<em1Axvi> | MGI:7489591

Name:	regulatory region 55; endonuclease-mediated mutation 1, Axel Visel
Allele Type:	Endonuclease-mediated
Attribute String:	Modified regulatory region

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Strain

MGI:7489916 | FVB-Rr426<em1Axvi>

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7489918 | FVB-Del(5Rr426-Rr108735)1Axvi

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Genotype

Symbol:	Rr426/Rr426
Background:	FVB-Rr426
Zygosity:	hm
Has Mutant Allele:	true

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Genotype

Symbol:	Del(5Rr426-Rr108735)1Axvi/Del(5Rr426-Rr108735)1Axvi
Background:	FVB-Del(5Rr426-Rr108735)1Axvi
Zygosity:	hm
Has Mutant Allele:	true

•

Strain

MGI:7489908 | FVB-Rr51<em1Axvi>

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:6348306 | FVB/NCrl-Rr51<em1Axvi>/Mmucd

Attribute String:

mutant strain, coisogenic, endonuclease-mediated mutation

•

Strain

MGI:7489914 | FVB-Rr55<em1Axvi>

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:6348310 | FVB/NCrl-Rr55<em1Axvi>/Mmucd

Attribute String:

mutant strain, coisogenic, endonuclease-mediated mutation

•

Allele

Tg(CAG-cat,-Tbx5)1Nemr | MGI:4361178

Name:	transgene insertion 1, Mona Nemer
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

•

Genotype

Symbol:	Rr51/Rr51
Background:	FVB-Rr51
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Rr55/Rr55
Background:	FVB-Rr55
Zygosity:	hm
Has Mutant Allele:	true

•

Protein

Q9CQS3

Organism:	Mus musculus/domesticus
Length:	217
Fragment?:	false

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Publication

21615908 | J:174073

First Author:	Lakner J
Year:	2011
Journal:	BMC Biochem
Title:	Characterization of the expression, promoter activity and molecular architecture of fibin.
Volume:	12

Pages:	26

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Protein Domain

IPR026772 | Fibin

Type:

Family

Description:

Fin bud initiation factor (Fibin) forms disulfide-linked homodimers. It seems to also exist as monomers []. It localises in endoplasmic reticulum and golgi apparatus [, ]. In zebrafish, Fibin is essential for the initiation of pectoral fin bud formation. It potentially acts downstream of retinoic acid and Wnt signaling and is required for tbx5 expression in the lateral plate mesoderm of presumptive pectoral fin bud regions []. In mammals is expressed in cerebellum, skeletal muscle and other embryonic and adult tissues, suggesting a relevant role during embryogenesis and adult life [].

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HT Experiment

E-GEOD-77576 | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse

Series Id:	GSE77576
Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	ArrayExpress

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HT Experiment

GSE63796 | Single cell expression profiles of the earliest cardiac precursor cells


Experiment Type:	RNA-Seq
Study Type:	Baseline
Source:	GEO

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Publication

9309177 | J:42452

First Author:	Smith J
Year:	1997
Journal:	Curr Opin Genet Dev
Title:	Brachyury and the T-box genes.
Volume:	7
Issue:	4
Pages:	474-80

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HT Experiment

E-GEOD-26191 | Chromatin Remodeling Complex Dosage Modulates Transcription Factor Function in Heart Development

Series Id:	GSE26191
Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	ArrayExpress

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Publication

17383611 | J:121493

First Author:	Böhm J
Year:	2007
Journal:	Biochem Biophys Res Commun
Title:	Synergistic cooperation of Sall4 and Cyclin D1 in transcriptional repression.
Volume:	356
Issue:	3
Pages:	773-9

•

Publication

18498088 | J:136359

First Author:	Sirbu IO
Year:	2008
Journal:	Dev Dyn
Title:	Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway.
Volume:	237
Issue:	6
Pages:	1627-35

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Publication

30787297 | J:275405

First Author:	Muraoka N
Year:	2019
Journal:	Nat Commun
Title:	Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming.
Volume:	10
Issue:	1
Pages:	674

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Publication

14709543 | J:87373

First Author:	Meilhac SM
Year:	2004
Journal:	J Cell Biol
Title:	Oriented clonal cell growth in the developing mouse myocardium underlies cardiac morphogenesis.
Volume:	164
Issue:	1
Pages:	97-109

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Publication

31116981 | J:288490

First Author:	Fernandez-Perez A
Year:	2019
Journal:	Cell Rep
Title:	Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming.
Volume:	27
Issue:	8
Pages:	2354-2369.e7

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Publication

9207801 | J:43886

First Author:	Bamshad M
Year:	1997
Journal:	Nat Genet
Title:	Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.
Volume:	16
Issue:	3
Pages:	311-5

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Publication

15548583 | J:94456

First Author:	Yu Q
Year:	2004
Journal:	Development
Title:	ENU induced mutations causing congenital cardiovascular anomalies.
Volume:	131
Issue:	24
Pages:	6211-23

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Publication

17184764 | J:118797

First Author:	Halilagic A
Year:	2007
Journal:	Dev Biol
Title:	Retinoids control anterior and dorsal properties in the developing forebrain.
Volume:	303
Issue:	1
Pages:	362-75

•

Publication

17413044 | J:137753

First Author:	Baurand A
Year:	2007
Journal:	Circ Res
Title:	Beta-catenin downregulation is required for adaptive cardiac remodeling.
Volume:	100
Issue:	9
Pages:	1353-62

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Publication

19073933 | J:142659

First Author:	Zelarayán LC
Year:	2008
Journal:	Proc Natl Acad Sci U S A
Title:	Beta-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.
Volume:	105
Issue:	50
Pages:	19762-7

•

Publication

25344074 | J:244244

First Author:	Nam YJ
Year:	2014
Journal:	Development
Title:	Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors.
Volume:	141
Issue:	22
Pages:	4267-78

•

Publication

24963028 | J:246466

First Author:	van Weerd JH
Year:	2014
Journal:	Circ Res
Title:	A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system.
Volume:	115
Issue:	4
Pages:	432-41

•

Publication

19854269 | J:156737

First Author:	Zhao L
Year:	2010
Journal:	Mech Dev
Title:	Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain.
Volume:	127
Issue:	1-2
Pages:	62-72

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Publication

24920580 | J:213570

First Author:	Muraoka N
Year:	2014
Journal:	EMBO J
Title:	MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.
Volume:	33
Issue:	14
Pages:	1565-81

•

Publication

26073556 | J:250500

First Author:	Hara M
Year:	2015
Journal:	Sci Rep
Title:	Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias.
Volume:	5

Pages:	11204

•

Publication

16332960 | J:118816

First Author:	Murakami M
Year:	2005
Journal:	Proc Natl Acad Sci U S A
Title:	A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome.
Volume:	102
Issue:	50
Pages:	18034-9

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Publication

12845333 | J:113930

First Author:	Garg V
Year:	2003
Journal:	Nature
Title:	GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5.
Volume:	424
Issue:	6947
Pages:	443-7

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Publication

19011045 | J:146335

First Author:	Li X
Year:	2009
Journal:	Am J Physiol Heart Circ Physiol
Title:	Na+/H+ exchanger isoform 1 facilitates cardiomyocyte embryonic stem cell differentiation.
Volume:	296
Issue:	1
Pages:	H159-70

•

Publication

9888994 | J:52301

First Author:	Yi CH
Year:	1999
Journal:	Genomics
Title:	Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.
Volume:	55
Issue:	1
Pages:	10-20

•

Publication

24147056 | J:209102

First Author:	Yu Z
Year:	2013
Journal:	PLoS One
Title:	Islet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expression.
Volume:	8
Issue:	10
Pages:	e77690

•

Publication

27569213 | J:236858

First Author:	Kim J
Year:	2016
Journal:	Cancer Res
Title:	Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways.
Volume:	76
Issue:	21
Pages:	6424-6435

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Publication

27834668 | J:262514

First Author:	Mohamed TM
Year:	2017
Journal:	Circulation
Title:	Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming.
Volume:	135
Issue:	10
Pages:	978-995

•

Publication

30587117 | J:269137

First Author:	Hori Y
Year:	2018
Journal:	BMC Genomics
Title:	Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs.
Volume:	19
Issue:	1
Pages:	967

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Publication

37669370 | J:345804

First Author:	Watanabe Y
Year:	2023
Journal:	Proc Natl Acad Sci U S A
Title:	Hey2 enhancer activity defines unipotent progenitors for left ventricular cardiomyocytes in juxta-cardiac field of early mouse embryo.
Volume:	120
Issue:	37
Pages:	e2307658120

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Publication

11161575 | J:67365

First Author:	Kisanuki YY
Year:	2001
Journal:	Dev Biol
Title:	Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.
Volume:	230
Issue:	2
Pages:	230-42

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Publication

23457456 | J:199401

First Author:	Chiplunkar AR
Year:	2013
Journal:	PLoS One
Title:	Krüppel-like factor 2 is required for normal mouse cardiac development.
Volume:	8
Issue:	2
Pages:	e54891

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Publication

22438573 | J:184018

First Author:	Itou J
Year:	2012
Journal:	Development
Title:	Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos.
Volume:	139
Issue:	9
Pages:	1620-9

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Publication

28674041 | J:267302

First Author:	Qiao Y
Year:	2017
Journal:	Circ Res
Title:	Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice.
Volume:	121
Issue:	5
Pages:	549-563

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Publication

11591645 | J:72157

First Author:	Margulies EH
Year:	2001
Journal:	Genome Res
Title:	A comparative molecular analysis of developing mouse forelimbs and hindlimbs using serial analysis of gene expression (SAGE).
Volume:	11
Issue:	10
Pages:	1686-98

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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