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Search results 301 to 391 out of 391 for Hic1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617719
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is in mesenchyme between and dorsal to the spinal ganglia where the dorsal roots enter the spinal cord and outlines the vertebral arches and ribs.
Specimen Label: 6f
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6356044
Age: embryonic day 12.5
Note: Expression is in mesenchyme between and dorsal to the spinal ganglia where the dorsal roots enter the spinal cord and in continuous bands at the levels of epaxial and hypaxial somite derivatives, and outlines the vertebral arches and ribs.
Specimen Label: 6h
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617719
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is medial and lateral surrounding the epaxial and hypaxial demomyotome derivatives, in mesenchyme surrounding peripheral nerves, and outlines the vertebral arches and ribs.
Specimen Label: 7b
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6356044
Age: embryonic day 12.5
Note: Expression is in epaxial and hypaxial mesenchyme associated with muscles and in mesenchyme surrounding epaxial and hypaxial peripheral nerves and is absent surrounding the proximal branches of the nerves.
Specimen Label: 7h
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Probe: MGI:7569161
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668816
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7569168
Age: embryonic day 10.0
Specimen Label: 2O
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3508341
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3508341
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:6290
Specimen Label: GUDMAP:6290
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:12747
Specimen Label: GUDMAP:12747
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:12748
Specimen Label: GUDMAP:12748
Detected: false
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2875323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:13342
Note: Expression is widespread in urethral mesenchyme.
Specimen Label: GUDMAP:13342
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is in cranio-facial mesenchyme near the joint anlage of the jaw.
Specimen Label: 6b
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6356044
Age: embryonic day 10.5
Note: Expression is in cranio-facial mesenchyme near the joint anlage of the jaw and in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye.
Specimen Label: 6a
Detected: true
Specimen Num: 1
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is in cranio-facial mesenchyme near the joint anlage of the jaw, around the cranial nerves, and in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye.
Specimen Label: 8a
Detected: true
Specimen Num: 19
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•
GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is around the cranial nerves.
Specimen Label: 8c
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Note: Expression is in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye and around the cranial nerves.
Specimen Label: 8d
Detected: true
Specimen Num: 21
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•
GXD Expression
GXD Expression
 
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6356044
Age: embryonic day 14.5
Note: Expression is around the cranial nerves.
Specimen Label: 8e
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6188988
Age: embryonic day 14.5
Image: 4a
Specimen Label: 4a
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6188988
Age: embryonic day 14.5
Image: 4b
Specimen Label: 4b
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6188932
Assay Type: RNA in situ
Annotation Date: 2018-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6188934
Age: embryonic day 14.5
Image: 4d
Specimen Label: 4d
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:6188932
Assay Type: RNA in situ
Annotation Date: 2018-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6188934
Age: embryonic day 13.5
Image: 4c
Specimen Label: 4c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6188989
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187621
Pattern: Single cells
Stage: TS21
Assay Id: MGI:6188991
Age: embryonic day 13.5
Image: 4f
Specimen Label: 4f
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
 
Probe: MGI:6188989
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187622
Pattern: Single cells
Stage: TS22
Assay Id: MGI:6188991
Age: embryonic day 14.5
Image: 4g
Specimen Label: 4g
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:6188989
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187622
Pattern: Single cells
Stage: TS22
Assay Id: MGI:6188991
Age: embryonic day 14.5
Image: 4h
Specimen Label: 4h
Detected: true
Specimen Num: 17
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6188989
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187626
Pattern: Single cells
Stage: TS26
Assay Id: MGI:6188991
Age: embryonic day 18.5
Image: 4j
Specimen Label: 4j
Detected: true
Specimen Num: 19
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6188988
Age: embryonic day 14.5
Image: 3f
Specimen Label: 3f
Detected: true
Specimen Num: 6
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6188988
Age: embryonic day 13.5
Image: 3e
Specimen Label: 3e
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6188988
Age: embryonic day 14.5
Image: 3g
Specimen Label: 3g
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:6290
Specimen Label: GUDMAP:6290
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507291
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540211
Age: embryonic day 15.5
Image: GUDMAP:12748
Specimen Label: GUDMAP:12748
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:218700
Assay Type: RNA in situ
Annotation Date: 2019-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6356044
Age: embryonic day 11.5
Specimen Label: 6b
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6188988
Age: embryonic day 11.5
Image: 3b
Specimen Label: 3b
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6188988
Age: embryonic day 15.5
Image: 3h
Specimen Label: 3h
Detected: true
Specimen Num: 8
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Publication
23459939 | J:203752
First Author: Yu DH
Year: 2013
Journal: Mol Cell Biol
Title: Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation.
Volume: 33
Issue: 9
Pages: 1845-58
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Publication
11527402 | J:71516
First Author: Chen CM
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Cloning, structure, and expression of the mouse Ovca1 gene.
Volume: 286
Issue: 5
Pages: 1019-26
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Publication
12905154 | J:85444
First Author: Yingling J
Year: 2003
Journal: Am J Hum Genet
Title: Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse.
Volume: 73
Issue: 3
Pages: 475-88
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Publication
11455436 | J:69868
First Author: Spörle R
Year: 2001
Journal: Dev Genes Evol
Title: Epaxial-adaxial-hypaxial regionalisation of the vertebrate somite: evidence for a somitic organiser and a mirror-image duplication.
Volume: 211
Issue: 4
Pages: 198-217
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Publication
24748541 | J:225226
First Author: Dykes IM
Year: 2014
Journal: Circ Res
Title: HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.
Volume: 115
Issue: 1
Pages: 23-31
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Publication
33482080 | J:300927
   
First Author: Han X
Year: 2021
Journal: Elife
Title: Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis.
Volume: 10
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Publication
36542062 | J:332217
   
First Author: Feng J
Year: 2022
Journal: Elife
Title: TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.
Volume: 11
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Publication
16844427 | J:116022
First Author: Coveney D
Year: 2007
Journal: Gene Expr Patterns
Title: A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.
Volume: 7
Issue: 1-2
Pages: 82-92
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Publication
34351428 | J:308922
 
First Author: Medeiros de Araújo JA
Year: 2021
Journal: Development
Title: ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.
Volume: 148
Issue: 16
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE226352 | Characterization of E13.5 forelimb gene expression after Hic1 knockout
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
18974104 | J:140643
First Author: Briggs KJ
Year: 2008
Journal: Cancer Res
Title: Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.
Volume: 68
Issue: 21
Pages: 8654-6
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Publication
12052894 | J:182410
First Author: Deltour S
Year: 2002
Journal: Mol Cell Biol
Title: The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.
Volume: 22
Issue: 13
Pages: 4890-901
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Publication
16762039 | J:180471
First Author: Stankovic-Valentin N
Year: 2006
Journal: FEBS J
Title: A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.
Volume: 273
Issue: 13
Pages: 2879-90
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Interaction Experiment
Deltour S (2002)
Description: The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.
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Interaction Experiment
Valenta T (2006)
Description: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.
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Publication
17283066 | -
First Author: Stankovic-Valentin N
Year: 2007
Journal: Mol Cell Biol
Title: An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.
Volume: 27
Issue: 7
Pages: 2661-75
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Allele
Hic1<tm2.1(cre/ERT2)Tmun> | MGI:6740447
Name: hypermethylated in cancer 1; targeted mutation 2.1, T Michael Underhill
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:6761385 | B6(Cg)-Hic1<tm2.1(cre/ERT2)Tmun>/J
Attribute String: mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Hic1/Hic1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hic1/Hic1<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Allele
Hic1<tm1.1Tmun> | MGI:6740446
Name: hypermethylated in cancer 1; targeted mutation 1.1, T Michael Underhill
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Strain
MGI:6761383 | STOCK Hic1<tm1.1Tmun>/J
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hic1/Hic1<+>
Background: involves: 129S6/SvEvTac * 129S2/SvPas * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hic1/Hic1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129 * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hic1/Hic1<+> Tg(Prrx1-cre)1Cjt/?
Background: involves: 129 * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Publication
28538185 | J:330778
First Author: Hassan HM
Year: 2017
Journal: Cell Rep
Title: Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.
Volume: 19
Issue: 8
Pages: 1685-1697
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Publication
29470501 | J:258742
First Author: Freschi A
Year: 2018
Journal: PLoS Genet
Title: Tissue-specific and mosaic imprinting defects underlie opposite congenital growth disorders in mice.
Volume: 14
Issue: 2
Pages: e1007243
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Publication
27621468 | J:238342
First Author: Hur SK
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Humanized H19/Igf2 locus reveals diverged imprinting mechanism between mouse and human and reflects Silver-Russell syndrome phenotypes.
Volume: 113
Issue: 39
Pages: 10938-43
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Publication
34132339 | J:308687
First Author: Freschi A
Year: 2021
Journal: Hum Mol Genet
Title: The number of the CTCF binding sites of the H19/IGF2:IG-DMR correlates with DNA methylation and expression imprinting in a humanized mouse model.
Volume: 30
Issue: 16
Pages: 1509-1520
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Publication
26619800 | J:255673
First Author: Fang M
Year: 2016
Journal: Biochim Biophys Acta
Title: HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.
Volume: 1859
Issue: 2
Pages: 294-305
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Publication
33258474 | J:300833
First Author: Hirakawa K
Year: 2021
Journal: Hum Mol Genet
Title: Transient establishment of imprinted DNA methylation of transgenic human IC1 sequence in mouse during the preimplantation period.
Volume: 29
Issue: 22
Pages: 3646-3661
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Publication
35853880 | J:326615
First Author: Wu T
Year: 2022
Journal: Cell Death Dis
Title: Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression.
Volume: 13
Issue: 7
Pages: 624
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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