Type |
Details |
Score |
Publication |
First Author: |
Chyuan IT |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
TRAIL-Mediated Suppression of T Cell Receptor Signaling Inhibits T Cell Activation and Inflammation in Experimental Autoimmune Encephalomyelitis. |
Volume: |
9 |
|
Pages: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Monteleone I |
Year: |
2016 |
Journal: |
J Crohns Colitis |
Title: |
Smad7 Knockdown Restores Aryl Hydrocarbon Receptor-mediated Protective Signals in the Gut. |
Volume: |
10 |
Issue: |
6 |
Pages: |
670-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fugmann SD |
Year: |
2002 |
Journal: |
Nature |
Title: |
DNA repair: breaking the seal. |
Volume: |
416 |
Issue: |
6882 |
Pages: |
691-4 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The variable portion of the genes encoding immunoglobulins and T cell receptors are assembled from component V, D, and J DNA segments by a site-specific recombination reaction termed V(D)J recombination. V(D)J recombination is targeted to specific sites on the chromosome by recombination signal sequences (RSSs) that flank antigen receptor gene segments. The RSS consists of a conserved heptamer (consensus, 5'-CACAGTG-3') and nonamer (consensus, 5'-ACAAAAACC-3') separated by a spacer of either 12 or 23 bp. Efficient recombination occurs between a 12-RSS and a 23-RSS, a restriction known as the 12/23 rule.V(D)J recombination can be divided into two phases, DNA cleavage and DNA joining. DNA cleavage requires two lymphocyte-specific factors, theproducts of the recombination activating genes, RAG1 and RAG2, which together recognise the RSSs and create double strand breaks at the RSS-coding segment junctions []. RAG-mediated DNA cleavage occurs in a synaptic complex termed the paired complex, which is constituted from two distinct RSS-RAG complexes, a 12-SC and a 23-SC (where SC stands for signal complex). The DNA cleavage reaction involves two distinct enzymatic steps, initial nicking that creates a 3'-OH between a coding segment and its RSS, followed by hairpin formation in which the newly created 3'-OH attacks a phosphodiester bond on the opposite DNA strand. This generates ablunt, 5' phosphorylated signal end containing all of the RSS elements, and a covalently sealed hairpin coding end. The second phase of V(D)J recombination, in which broken DNA fragments are processed and joined, is less well characterised. Signal ends are typically joinedprecisely to form a signal joint, whereas joining of the coding ends requires the hairpin structure to be opened and typically involves nucleotide addition and deletionbefore formation of the coding joint. The factors involved in these processes include ubiquitously expressed proteins involved in the repair of DNA double strandbreaks by nonhomologous end joining, terminal deoxynucleotidyl transferase, and Artemis protein.In addition to their critical roles in RSS recognition and DNA cleavage, the RAG proteins may perform two distinct types of functions in thepostcleavage phase of V(D)J. A structural function has been inferredfrom the finding that, after DNA cleavage in vitro, the DNA ends remain associated with the RAG proteins in a "four end"complex known as the cleaved signalcomplex. After release of the coding ends in vitro, and after coding joint formation in vivo, the RAG proteins remain in astable signal end complex (SEC) containing the two signal ends. These postcleavage complexes may serveas essential scaffolds for the second phase of the reaction, with the RAG proteins acting to organise the DNA processing and joining events. The second type of RAG protein-mediated postcleavage activity is the catalysis of phosphodiester bond hydrolysis and strand transfer reactions. The RAG proteins are capable of opening hairpin coding ends in vitro. The RAG proteinsalso show 3' flap endonuclease activity that may contribute to coding end processing/joining and can utilise the3' OH group on the signal ends to attack hairpin coding ends (forming hybrid or open/shut joints) or virtually any DNA duplex (forming a transposition product). |
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Strain |
Attribute String: |
congenic, targeted mutation |
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•
•
•
•
•
|
Strain |
Attribute String: |
congenic, endonuclease-mediated mutation, mutant strain, targeted mutation |
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•
•
•
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
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Strain |
Attribute String: |
congenic, mutant strain, spontaneous mutation, targeted mutation |
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•
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Strain |
Attribute String: |
congenic, mutant strain, spontaneous mutation, targeted mutation |
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•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, targeted mutation, mutant strain, congenic |
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•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
•
•
|
Publication |
First Author: |
Korn LL |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Regulatory T cells occupy an isolated niche in the intestine that is antigen independent. |
Volume: |
9 |
Issue: |
5 |
Pages: |
1567-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verheijen M |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life. |
Volume: |
33 |
Issue: |
7 |
Pages: |
108376 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, transgenic, mutant strain, congenic |
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•
•
•
•
|
Publication |
First Author: |
Schwarz BA |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Selective thymus settling regulated by cytokine and chemokine receptors. |
Volume: |
178 |
Issue: |
4 |
Pages: |
2008-17 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, targeted mutation, transgenic |
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•
•
•
•
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Strain |
Attribute String: |
targeted mutation, transgenic, congenic, radiation induced mutation |
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•
•
•
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Strain |
Attribute String: |
congenic, targeted mutation, transgenic |
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•
•
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•
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, spontaneous mutation |
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•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
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•
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•
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Strain |
Attribute String: |
congenic, targeted mutation |
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•
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•
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Strain |
Attribute String: |
targeted mutation, transgenic, mutant strain, congenic |
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•
|
Publication |
First Author: |
Romagnoli P |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
The thymic niche does not limit development of the naturally diverse population of mouse regulatory T lymphocytes. |
Volume: |
189 |
Issue: |
8 |
Pages: |
3831-7 |
|
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•
•
•
•
|
Publication |
First Author: |
Dong J |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus. |
Volume: |
8 |
Issue: |
2 |
Pages: |
e56378 |
|
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•
•
•
•
|
Publication |
First Author: |
Rubtsov YP |
Year: |
2010 |
Journal: |
Science |
Title: |
Stability of the regulatory T cell lineage in vivo. |
Volume: |
329 |
Issue: |
5999 |
Pages: |
1667-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Chami E |
Year: |
2016 |
Journal: |
Aging Cell |
Title: |
Interleukin-21 administration to aged mice rejuvenates their peripheral T-cell pool by triggering de novo thymopoiesis. |
Volume: |
15 |
Issue: |
2 |
Pages: |
349-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baranek T |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. |
Volume: |
32 |
Issue: |
10 |
Pages: |
108116 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1<+> Tg(LPV-TAg1135)11Tvd/? |
Background: |
involves: 129/Sv * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(LPV-TAg1135)11Tvd/? |
Background: |
involves: 129/Sv * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Foxp3/? Rag1/Rag1 Tg(TcraTcrb)425Cbn/? |
Background: |
Not Specified |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Igh-J/Igh-J Igk-J/Igk-J Rag1/Rag1 Tg(DO11.10)10Dlo/? |
Background: |
involves: 129S/Sv * BALB/c * C3H * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
H2-Ab1/H2-Ab1 Rag1/Rag1 Tg(HLA-DQA1,HLA-DQB1)73Myl/? |
Background: |
NOD.Cg-Rag1 H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)73Myl |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag2/Rag1/Rag2 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag2/Rag1/Rag2 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Trp53/Trp53 Xrcc5/Xrcc5 |
Background: |
involves: 129S7/SvEvBrd * C57BL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tyrp1/Tyrp1 Tg(Tcra,Tcrb)9Rest/? |
Background: |
involves: 101/Rl * 129S7/SvEvBrd * C3H/Rl * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(Tcra,Tcrb)HRCAll/? |
Background: |
B6.Cg-Rag1 Tg(Tcra,Tcrb)HRCAll |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Man2a1/Man2a1 Rag1/Rag1 |
Background: |
B6.129-Rag1 Man2a1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itk/Itk Rag1/Rag1 Tg(Tcra5CC7,Tcrb5CC7)IWep/? |
Background: |
involves: 129 * C57BL/10 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ctla4/Ctla4 Rag1/Rag1 Tg(TcrAND)53Hed/? |
Background: |
involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ctla4/Ctla4 Rag1/Rag1 Tg(TcraTcrb)8Rest/? |
Background: |
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Mpz/Mpz<+> Rag1/Rag1 |
Background: |
B6.129S7-Mpz Rag1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ndfip1/Ndfip1 Rag1/Rag1 Tg(TcraTcrb)425Cbn/? |
Background: |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * BALB/c * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdpn/Pdpn Rag1/Rag1 Tg(Pdgfrb-cre)9Rha/? |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Col1a1/Col1a1<+> Rag1/Rag1 Tg(KRT5-rtTA)T2D6Sgkd/? |
Background: |
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Palmer VL |
Year: |
2018 |
Journal: |
Cell Immunol |
Title: |
IL10 restrains autoreactive B cells in transgenic mice expressing inactive RAG1. |
Volume: |
331 |
|
Pages: |
110-120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boberg E |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia. |
Volume: |
11 |
|
Pages: |
1058 |
|
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
148
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells. |
Volume: |
14 |
Issue: |
5 |
Pages: |
1041-1048 |
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•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
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Strain |
Attribute String: |
congenic, mutant strain, spontaneous mutation, targeted mutation, transgenic |
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•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant strain, congenic, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, spontaneous mutation, mutant strain, congenic |
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•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, spontaneous mutation, congenic |
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•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, spontaneous mutation, congenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2021 |
Journal: |
Immunity |
Title: |
Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges. |
Volume: |
54 |
Issue: |
12 |
Pages: |
2784-2794.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guy-Grand D |
Year: |
2003 |
Journal: |
J Exp Med |
Title: |
Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. |
Volume: |
197 |
Issue: |
3 |
Pages: |
333-41 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
de Pooter RF |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Lymphomyeloid-Primed Progenitor Cell Fates Are Controlled by the Transcription Factor Tal1. |
Volume: |
202 |
Issue: |
10 |
Pages: |
2837-2842 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hale JS |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision. |
Volume: |
186 |
Issue: |
2 |
Pages: |
799-806 |
|
•
•
•
•
•
|
Publication |
First Author: |
White AJ |
Year: |
2017 |
Journal: |
J Exp Med |
Title: |
A type 2 cytokine axis for thymus emigration. |
Volume: |
214 |
Issue: |
8 |
Pages: |
2205-2216 |
|
•
•
•
•
•
|
Publication |
First Author: |
Egawa T |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene. |
Volume: |
108 |
Issue: |
36 |
Pages: |
14873-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu Z |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment. |
Volume: |
21 |
Issue: |
1 |
Pages: |
168-180 |
|
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•
•
•
•
|
Strain |
Attribute String: |
mutant strain, congenic, targeted mutation, transgenic |
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•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, congenic, targeted mutation, transgenic, spontaneous mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth. |
Volume: |
10 |
Issue: |
1 |
Pages: |
5498 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhaumik S |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants. |
Volume: |
190 |
Issue: |
6 |
Pages: |
2603-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCarthy NI |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development. |
Volume: |
195 |
Issue: |
6 |
Pages: |
2675-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2018 |
Journal: |
Eur J Immunol |
Title: |
Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus. |
Volume: |
48 |
Issue: |
5 |
Pages: |
844-854 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peligero-Cruz C |
Year: |
2020 |
Journal: |
Elife |
Title: |
IL18 signaling promotes homing of mature Tregs into the thymus. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Chougnet CA |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
A major role for Bim in regulatory T cell homeostasis. |
Volume: |
186 |
Issue: |
1 |
Pages: |
156-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jimeno R |
Year: |
2019 |
Journal: |
Elife |
Title: |
Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nobrega C |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
T cells home to the thymus and control infection. |
Volume: |
190 |
Issue: |
4 |
Pages: |
1646-58 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/? |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1<+> Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/? |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
H2-Ab1/H2-Ab1 Rag1/Rag1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell |
Background: |
NOD.Cg-Rag1 H2-Ab1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Slc46a2/Slc46a2<+> Tg(TcraB12,TcrbB12)1Rest/? |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ins2/Ins2<+> Prf1/Prf1 Rag1/Rag1 |
Background: |
NOD.Cg-Rag1 Ins2 Prf1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Ins2/Ins2 Prf1/Prf1 Rag1/Rag1 |
Background: |
NOD.Cg-Rag1 Ins2 Prf1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Foxo1/Foxo1 Rag1/Rag1 Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/? |
Background: |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Foxo1/Foxo1 Rag1/Rag1 Tg(CD2-Il7r)1Asin/? Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/? |
Background: |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Nlrp3/Nlrp3<+> Rag1/Rag1 Lyz2/Lyz2<+> |
Background: |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Gt(ROSA)26Sor/? Il5/Il5<+> Rag1/Rag1 |
Background: |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)hiKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/? |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)loKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/? |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Cmtm7/Cmtm7<+> Rag1/Rag1 |
Background: |
chimera involves: C57BL/6 * C57BL/6N |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Ctps1/Ctps1 Tg(Cd4-cre)1Cwi/? Foxp3/? Rag1/Rag1<+> |
Background: |
mixed |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Rag1/Rag1 Tg(Foxp3-EGFP/cre)1cJbs/? |
Background: |
NOD.Cg-Rag1 Tg(Foxp3-EGFP/cre)1cJbs/J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
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Fragment?: |
false |
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