Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1001 to 1027 out of 1027 for Robo1

<< First < Previous | Next > Last >>

0.038s

Type

Details

Score

Allele

Robo1<em1Smoc> | MGI:7292096

Name:	roundabout guidance receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

•

GXD Expression

Probe:	MGI:5752616
Assay Type:	Immunohistochemistry
Annotation Date:	2016-03-22
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3266520
Pattern:	Regionally restricted
Stage:	TS20
Assay Id:	MGI:5752744
Age:	embryonic day 12.5

Note:	Expression appeared to be complementary to that of Robo3 within the subpallium, while overlapping with Robo1 in the lateral ganglionic eminence.
Specimen Label:	S1E
Detected:	true
Specimen Num:	3

•

GXD Expression

Probe:	MGI:5752616
Assay Type:	Immunohistochemistry
Annotation Date:	2016-03-22
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3747020
Pattern:	Regionally restricted
Stage:	TS20
Assay Id:	MGI:5752744
Age:	embryonic day 12.5

Note:	Expression appeared to be complementary to that of Robo3 within the subpallium, while overlapping with Robo1 in the lateral ganglionic eminence.
Specimen Label:	S1E
Detected:	true
Specimen Num:	3

•

GXD Expression

Probe:	MGI:5752618
Assay Type:	Immunohistochemistry
Annotation Date:	2016-03-22
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3747020
Pattern:	Regionally restricted
Stage:	TS20
Assay Id:	MGI:5752742
Age:	embryonic day 12.5

Note:	Robo1 and Robo3 showed similar patterns of expression both within the lateral and medial ganglionic eminences, and overlapped in regions where Robo1 protein was most robustly localized.
Specimen Label:	S1F
Detected:	true
Specimen Num:	14

•

GXD Expression

Probe:	MGI:5752618
Assay Type:	Immunohistochemistry
Annotation Date:	2016-03-22
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3747120
Pattern:	Regionally restricted
Stage:	TS20
Assay Id:	MGI:5752742
Age:	embryonic day 12.5

Note:	Robo1 and Robo3 showed similar patterns of expression both within the lateral and medial ganglionic eminences, and overlapped in regions where Robo1 protein was most robustly localized.
Specimen Label:	S1F
Detected:	true
Specimen Num:	14

•

GXD Expression

Probe:	MGI:2153065
Assay Type:	Immunohistochemistry
Annotation Date:	2016-03-22
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1754421
Pattern:	Not Specified
Stage:	TS21
Assay Id:	MGI:5752757
Age:	embryonic day 13.5

Note:	Expressed in the cortical interneurons. There was a decrease in the total number of labeled cells relative to an animal which was heterozygote for both Robo1 and Robo2 receptors and fully deficient for the Robo3 receptor.
Specimen Label:	not shown
Detected:	true
Specimen Num:	10

•

Protein Domain

IPR037451 | srGAP1_F-BAR

Type:

Domain

Description:

The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].This entry represents the F-BAR domain of srGAP1. srGAP1, also called Rho GTPase-Activating Protein 13 (ARHGAP13), is a Cdc42- and RhoA-specific GAP and is expressed later in the development of CNS (central nervous system) tissues. It is an important downstream signaling molecule of Robo1 [, ].

•

HT Experiment

GSE132730 | Design logic of hypothalamus development mapped by single-cell RNA-seq


Experiment Type:	RNA-Seq
Study Type:	Baseline
Source:	GEO

•

Publication

20438712 | J:162506

First Author:	Yang XM
Year:	2010
Journal:	Biochem Biophys Res Commun
Title:	Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
Volume:	396
Issue:	2
Pages:	571-7

•

Publication

30726731 | J:280112

First Author:	Dun XP
Year:	2019
Journal:	Cell Rep
Title:	Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge.
Volume:	26
Issue:	6
Pages:	1458-1472.e4

•

Publication

19137586 | J:146175

First Author:	Bacon C
Year:	2009
Journal:	J Comp Neurol
Title:	Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.
Volume:	513
Issue:	2
Pages:	224-36

•

Publication

25947198 | J:250817

First Author:	Castillo-Paterna M
Year:	2015
Journal:	EMBO Rep
Title:	DCC functions as an accelerator of thalamocortical axonal growth downstream of spontaneous thalamic activity.
Volume:	16
Issue:	7
Pages:	851-62

•

Publication

25975775 | J:229438

First Author:	Andrews WD
Year:	2016
Journal:	J Comp Neurol
Title:	Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.
Volume:	524
Issue:	3
Pages:	518-34

•

Publication

28507510 | J:269356

First Author:	Sano N
Year:	2017
Journal:	Front Cell Neurosci
Title:	Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1.
Volume:	11

Pages:	123

•

Publication

32999457 | J:297392

First Author:	Tavora B
Year:	2020
Journal:	Nature
Title:	Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.
Volume:	586
Issue:	7828
Pages:	299-304

•

Publication

26244297 | J:230944

First Author:	Li S
Year:	2015
Journal:	Invest Ophthalmol Vis Sci
Title:	Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies.
Volume:	56
Issue:	9
Pages:	5210-7

•

Publication

19909249 | J:174760

First Author:	Verissimo AR
Year:	2009
Journal:	Biochem Soc Trans
Title:	Functionally defining the endothelial transcriptome, from Robo4 to ECSCR.
Volume:	37
Issue:	Pt 6
Pages:	1214-7

•

Publication

24065825 | J:202310

First Author:	Yang YH
Year:	2013
Journal:	Proc Natl Acad Sci U S A
Title:	Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.
Volume:	110
Issue:	41
Pages:	16480-5

•

Publication

27725190 | J:250989

First Author:	Sharifpanah F
Year:	2016
Journal:	Biochim Biophys Acta
Title:	Mechanical strain stimulates vasculogenesis and expression of angiogenesis guidance molecules of embryonic stem cells through elevation of intracellular calcium, reactive oxygen species and nitric oxide generation.
Volume:	1863
Issue:	12
Pages:	3096-3105

•

Publication

31084928 | J:290895

First Author:	Park SJ
Year:	2019
Journal:	Biochem Biophys Res Commun
Title:	SLIT2 inhibits osteoclastogenesis and bone resorption by suppression of Cdc42 activity.
Volume:	514
Issue:	3
Pages:	868-874

•

Publication

31972158 | J:299725

First Author:	Wang X
Year:	2020
Journal:	Am J Pathol
Title:	miR-218 Expressed in Endothelial Progenitor Cells Contributes to the Development and Repair of the Kidney Microvasculature.
Volume:	190
Issue:	3
Pages:	642-659

•

Publication

32760720 | J:337269

First Author:	Wang L
Year:	2020
Journal:	Front Cell Dev Biol
Title:	SLIT2 Overexpression in Periodontitis Intensifies Inflammation and Alveolar Bone Loss, Possibly via the Activation of MAPK Pathway.
Volume:	8

Pages:	593

•

Publication

23505444 | -

First Author:	Ma Y
Year:	2013
Journal:	PLoS One
Title:	The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.
Volume:	8
Issue:	3
Pages:	e57865

•

Publication

20810653 | -

First Author:	Guo S
Year:	2010
Journal:	J Biol Chem
Title:	srGAP2 arginine methylation regulates cell migration and cell spreading through promoting dimerization.
Volume:	285
Issue:	45
Pages:	35133-41

•

Publication

19549836 | -

First Author:	Wang Q
Year:	2009
Journal:	Proc Natl Acad Sci U S A
Title:	Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
Volume:	106
Issue:	31
Pages:	12700-5

•

Protein

Q91Z69

Organism:	Mus musculus/domesticus
Length:	1062
Fragment?:	false

•

Protein

D3YZW1

Organism:	Mus musculus/domesticus
Length:	1085
Fragment?:	false

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do;jsessionid=81030AF7538EAE16DECA0159C8C550DC?searchTerm=Robo1&searchBag=&searchOffset=1000

MouseMine

Search our database by keyword

Examples

Search results 1001 to 1027 out of 1027 for Robo1

Categories

Hits by Pathway

Hits by Strain

Hits by Category