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Search results 801 to 878 out of 878 for Csf1

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Type Details Score
Publication
28759039 | J:251583
First Author: Gallagher EJ
Year: 2017
Journal: Oncogene
Title: Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia.
Volume: 36
Issue: 46
Pages: 6462-6471
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Publication
10441168 | J:56653
First Author: George J
Year: 1999
Journal: J Autoimmun
Title: The involvement of beta2-glycoprotein I (beta2-GPI) in human and murine atherosclerosis.
Volume: 13
Issue: 1
Pages: 57-60
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Publication
11592107 | J:71794
First Author: Calara F
Year: 2001
Journal: J Pathol
Title: Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice.
Volume: 195
Issue: 2
Pages: 257-63
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Publication
19416717 | J:148485
First Author: Thorp E
Year: 2009
Journal: Cell Metab
Title: Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.
Volume: 9
Issue: 5
Pages: 474-81
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Publication
8656070 | J:29950
First Author: Tangirala RK
Year: 1995
Journal: J Lipid Res
Title: Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.
Volume: 36
Issue: 11
Pages: 2320-8
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Publication
23283348 | J:193915
First Author: Carlo AS
Year: 2013
Journal: J Neurosci
Title: The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.
Volume: 33
Issue: 1
Pages: 358-70
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Publication
25705917 | J:241338
First Author: Yin Y
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway.
Volume: 35
Issue: 4
Pages: 804-16
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Strain
MGI:6402048 | NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl> Tg(CMV-IL3,CSF2,KITLG)1Eav Tg(CSF1)3Sz/J
Attribute String: mutant strain, spontaneous mutation, targeted mutation, transgenic, congenic
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Publication
22729249 | J:187643
First Author: Wang Y
Year: 2012
Journal: Nat Immunol
Title: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia.
Volume: 13
Issue: 8
Pages: 753-60
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Publication
31242418 | J:284942
First Author: Zhou LJ
Year: 2019
Journal: Cell Rep
Title: Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain.
Volume: 27
Issue: 13
Pages: 3844-3859.e6
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Publication
29422500 | J:257961
First Author: Soncin I
Year: 2018
Journal: Nat Commun
Title: The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.
Volume: 9
Issue: 1
Pages: 582
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Publication
36034743 | J:337190
First Author: Grune J
Year: 2022
Journal: Nat Cardiovasc Res
Title: Neutrophils incite and macrophages avert electrical storm after myocardial infarction.
Volume: 1
Issue: 7
Pages: 649-664
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Publication
36928411 | J:338559
First Author: Vanneste D
Year: 2023
Journal: Nat Immunol
Title: MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation.
Volume: 24
Issue: 5
Pages: 827-840
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Publication
37742194 | J:341989
First Author: Weilinger NL
Year: 2023
Journal: Cell Rep
Title: Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts.
Volume: 42
Issue: 10
Pages: 113128
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Publication
37216116 | J:335888
First Author: Strickland AB
Year: 2023
Journal: iScience
Title: Alternatively activated lung alveolar and interstitial macrophages promote fungal growth.
Volume: 26
Issue: 5
Pages: 106717
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Publication
24145216 | J:314263
 
First Author: Pridans C
Year: 2013
Journal: Sci Rep
Title: CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function.
Volume: 3
Pages: 3013
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Publication
34714329 | J:316326
 
First Author: Zhang N
Year: 2021
Journal: J Exp Med
Title: LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth.
Volume: 218
Issue: 12
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Publication
36951731 | J:340791
 
First Author: Zuo C
Year: 2023
Journal: J Exp Med
Title: Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy.
Volume: 220
Issue: 6
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Publication
38092736 | J:343555
First Author: Babaeijandaghi F
Year: 2023
Journal: Nat Commun
Title: DPPIV(+) fibro-adipogenic progenitors form the niche of adult skeletal muscle self-renewing resident macrophages.
Volume: 14
Issue: 1
Pages: 8273
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Publication
7683918 | -
First Author: Bourette RP
Year: 1993
Journal: Blood
Title: Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential.
Volume: 81
Issue: 10
Pages: 2511-20
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Publication
6582485 | -
First Author: Hampe A
Year: 1984
Journal: Proc Natl Acad Sci U S A
Title: Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
Volume: 81
Issue: 1
Pages: 85-9
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Publication
14709771 | -
First Author: Sapi E
Year: 2004
Journal: Exp Biol Med (Maywood)
Title: The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update.
Volume: 229
Issue: 1
Pages: 1-11
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Publication
22197934 | -
First Author: Rademakers R
Year: 2011
Journal: Nat Genet
Title: Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.
Volume: 44
Issue: 2
Pages: 200-5
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Publication
2849512 | -
First Author: Woolford J
Year: 1988
Journal: Cell
Title: Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype.
Volume: 55
Issue: 6
Pages: 965-77
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Publication
1834054 | -
 
First Author: Tamura T
Year: 1991
Journal: Behring Inst Mitt
Title: Transforming mechanism of the feline sarcoma virus encoded v-fms oncogene product.
Issue: 89
Pages: 93-9
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Publication
2843495 | -
 
First Author: Rettenmier CW
Year: 1986
Journal: Princess Takamatsu Symp
Title: Requirements for transformation by the fms oncogene product (CSF-1 receptor).
Volume: 17
Pages: 211-8
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Protein Domain
IPR030658 | CSF-1_receptor
Type: Family
Description: This entry represents a macrophage colony-stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR) or CD115 (Cluster of Differentiation 115). CSF1R is a tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes []. CSF-1 and CSF-1R play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis []. Mutations in the CSF1R gene cause hereditary diffuse leukoencephalopathy with spheroids, which is an autosomal-dominant central nervous system white-matter disease with variable clinical presentations, including personality and behavioral changes, dementia, depression, parkinsonism, seizures and other phenotypes [].This entry also includes the tyrosine-protein kinase transforming protein v-fms from Feline sarcoma virus. CSF1R (the c-fms product) is its cellular counterpart. It differs in some amino acid substitutions and the replacement of 50 C-terminal amino acids by 11 unrelated residues in v-fms [, , ]. v-fms can bind CSF-1 and has constitutive tyrosine-specific protein kinase activity, providing growth stimulatory signals in the absence of ligand [].
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Publication
17442114 | -
First Author: Kunin V
Year: 2007
Journal: Genome Biol
Title: Evolutionary conservation of sequence and secondary structures in CRISPR repeats.
Volume: 8
Issue: 4
Pages: R61
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Publication
17379808 | -
First Author: Barrangou R
Year: 2007
Journal: Science
Title: CRISPR provides acquired resistance against viruses in prokaryotes.
Volume: 315
Issue: 5819
Pages: 1709-12
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Publication
16545108 | -
 
First Author: Makarova KS
Year: 2006
Journal: Biol Direct
Title: A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action.
Volume: 1
Pages: 7
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Publication
21699496 | -
First Author: Howard JA
Year: 2011
Journal: Biochem J
Title: Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein.
Volume: 439
Issue: 1
Pages: 85-95
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Publication
24459147 | -
First Author: Brendel J
Year: 2014
Journal: J Biol Chem
Title: A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii.
Volume: 289
Issue: 10
Pages: 7164-77
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Publication
25474352 | J:222183
First Author: Ramsey SA
Year: 2014
Journal: PLoS Genet
Title: Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway.
Volume: 10
Issue: 12
Pages: e1004828
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Publication
10195942 | J:55980
First Author: Plump AS
Year: 1999
Journal: Arterioscler Thromb Vasc Biol
Title: Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.
Volume: 19
Issue: 4
Pages: 1105-10
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Publication
8550828 | J:111394
First Author: Masucci-Magoulas L
Year: 1996
Journal: J Clin Invest
Title: Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels.
Volume: 97
Issue: 1
Pages: 154-61
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Publication
15372102 | J:92843
First Author: Kobayashi T
Year: 2004
Journal: J Clin Invest
Title: Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice.
Volume: 114
Issue: 6
Pages: 784-94
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Publication
24662052 | J:215359
First Author: Garcia AJ
Year: 2014
Journal: Mol Cell Biol
Title: Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression.
Volume: 34
Issue: 11
Pages: 2017-28
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Publication
38069208 | J:343562
 
First Author: Larsen MC
Year: 2023
Journal: Int J Mol Sci
Title: AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors.
Volume: 24
Issue: 23
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Publication
29252214 | J:258339
First Author: Janova H
Year: 2018
Journal: J Clin Invest
Title: Microglia ablation alleviates myelin-associated catatonic signs in mice.
Volume: 128
Issue: 2
Pages: 734-745
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Publication
36883865 | J:335755
First Author: Amano S
Year: 2023
Journal: J Immunol
Title: Commensal Bacteria and the Lung Environment Are Responsible for Th2-Mediated Memory Yielding Natural IgE in MyD88-Deficient Mice.
Volume: 210
Issue: 7
Pages: 959-972
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Publication
27601030 | J:247030
First Author: Qing X
Year: 2016
Journal: Eur J Immunol
Title: iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Volume: 46
Issue: 12
Pages: 2737-2748
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Publication
27428900 | J:240122
First Author: Theurl I
Year: 2016
Journal: Nat Med
Title: On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.
Volume: 22
Issue: 8
Pages: 945-51
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Publication
30336142 | J:266634
 
First Author: Zhang X
Year: 2018
Journal: J Mol Cell Cardiol
Title: Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Volume: 125
Pages: 6-17
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Publication
26261265 | J:227135
First Author: Qian BZ
Year: 2015
Journal: J Exp Med
Title: FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.
Volume: 212
Issue: 9
Pages: 1433-48
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Publication
33841415 | J:308249
 
First Author: Cheng B
Year: 2021
Journal: Front Immunol
Title: Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival.
Volume: 12
Pages: 633796
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Publication
33620118 | J:316260
First Author: Marzan DE
Year: 2021
Journal: Glia
Title: Activated microglia drive demyelination via CSF1R signaling.
Volume: 69
Issue: 6
Pages: 1583-1604
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Publication
24769444 | J:212553
First Author: Qin L
Year: 2014
Journal: Cancer Res
Title: NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis.
Volume: 74
Issue: 13
Pages: 3477-88
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Publication
22039576 | J:185635
First Author: DeNardo DG
Year: 2011
Journal: Cancer Discov
Title: Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy.
Volume: 1
Issue: 1
Pages: 54-67
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Publication
29196442 | J:258269
 
First Author: Muthukrishnan SD
Year: 2018
Journal: Dis Model Mech
Title: Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney.
Volume: 11
Issue: 1
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Publication
35062962 | J:320959
First Author: Zhou K
Year: 2022
Journal: J Neuroinflammation
Title: An overlooked subset of Cx3cr1wt/wt microglia in the Cx3cr1CreER-Eyfp/wt mouse has a repopulation advantage over Cx3cr1CreER-Eyfp/wt microglia following microglial depletion.
Volume: 19
Issue: 1
Pages: 20
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Publication
31595043 | J:310419
First Author: Aikawa S
Year: 2020
Journal: Cell Death Differ
Title: Uterine deficiency of high-mobility group box-1 (HMGB1) protein causes implantation defects and adverse pregnancy outcomes.
Volume: 27
Issue: 5
Pages: 1489-1504
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Publication
35333324 | J:324722
 
First Author: Stables J
Year: 2022
Journal: Development
Title: A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling.
Volume: 149
Issue: 8
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Publication
36147476 | J:328896
First Author: Liu F
Year: 2022
Journal: Int J Biol Sci
Title: Csf1r mediates enhancement of intestinal tumorigenesis caused by inactivation of Mir34a.
Volume: 18
Issue: 14
Pages: 5415-5437
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Publication
25241894 | J:222507
First Author: Mathsyaraja H
Year: 2015
Journal: Oncogene
Title: CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Volume: 34
Issue: 28
Pages: 3651-61
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Publication
22919031 | J:192947
First Author: He H
Year: 2012
Journal: Blood
Title: Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Volume: 120
Issue: 15
Pages: 3152-62
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Publication
37445982 | J:337955
 
First Author: Toejing P
Year: 2023
Journal: Int J Mol Sci
Title: Accelerated Bone Loss in Transgenic Mice Expressing Constitutively Active TGF-β Receptor Type I.
Volume: 24
Issue: 13
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Publication
27956588 | J:237486
First Author: Barrott JJ
Year: 2016
Journal: J Exp Med
Title: Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation.
Volume: 213
Issue: 13
Pages: 2989-3005
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Publication
27677742 | J:237846
First Author: Galletti G
Year: 2016
Journal: Leukemia
Title: B cells and macrophages pursue a common path toward the development and progression of chronic lymphocytic leukemia.
Volume: 30
Issue: 12
Pages: 2293-2301
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Publication
29440354 | J:258848
First Author: Hawley CA
Year: 2018
Journal: J Immunol
Title: Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.
Volume: 200
Issue: 6
Pages: 2209-2223
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Publication
23314290 | J:318131
First Author: Akcora D
Year: 2013
Journal: Stem Cell Res
Title: The CSF-1 receptor fashions the intestinal stem cell niche.
Volume: 10
Issue: 2
Pages: 203-12
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Publication
33607650 | J:303673
First Author: Zhu M
Year: 2021
Journal: PLoS One
Title: Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen.
Volume: 16
Issue: 2
Pages: e0247199
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Publication
30971820 | J:282859
First Author: Jacome-Galarza CE
Year: 2019
Journal: Nature
Title: Developmental origin, functional maintenance and genetic rescue of osteoclasts.
Volume: 568
Issue: 7753
Pages: 541-545
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Publication
34721382 | J:312416
 
First Author: Bhattacharjee O
Year: 2021
Journal: Front Immunol
Title: Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin.
Volume: 12
Pages: 718005
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Publication
24892425 | J:218512
First Author: Forget MA
Year: 2014
Journal: PLoS One
Title: Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.
Volume: 9
Issue: 6
Pages: e98623
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Publication
28751473 | J:252713
First Author: Summers KM
Year: 2017
Journal: J Leukoc Biol
Title: Identification of the macrophage-specific promoter signature in FANTOM5 mouse embryo developmental time course data.
Volume: 102
Issue: 4
Pages: 1081-1092
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Publication
25088194 | J:259073
First Author: Patsialou A
Year: 2015
Journal: Oncogene
Title: Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells.
Volume: 34
Issue: 21
Pages: 2721-31
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Publication
36909235 | J:334254
 
First Author: Bautista CA
Year: 2023
Journal: Front Physiol
Title: CD206+ tendon resident macrophages and their potential crosstalk with fibroblasts and the ECM during tendon growth and maturation.
Volume: 14
Pages: 1122348
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Publication
30647151 | J:273194
First Author: Anderson SR
Year: 2019
Journal: J Neurosci
Title: Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.
Volume: 39
Issue: 11
Pages: 2025-2040
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Publication
36037587 | J:328345
 
First Author: Wendt S
Year: 2022
Journal: Redox Biol
Title: Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress.
Volume: 56
Pages: 102448
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Protein
P09581
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q3U1X4
Organism: Mus musculus/domesticus
Length: 945  
Fragment?: true
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Protein
Q0P635
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q3U1Y3
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q3U4N8
Organism: Mus musculus/domesticus
Length: 922  
Fragment?: true
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Protein
Q3UKC6
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q3U210
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q6NXV8
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q3U3W0
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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