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Search results 1 to 100 out of 550 for Irf6

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
3664 | IRF6
Type: gene
Organism: human
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Gene
457701 | IRF6
Type: gene
Organism: chimpanzee
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Gene
614253 | IRF6
Type: gene
Organism: cattle
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Gene
419863 | IRF6
Type: gene
Organism: chicken
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Gene
393570 | irf6
Type: gene
Organism: zebrafish
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Gene
712958 | IRF6
Type: gene
Organism: macaque, rhesus
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Gene
594908 | irf6
Type: gene
Organism: frog, western clawed
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Gene
364081 | Irf6
Type: gene
Organism: rat
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Gene
480015 | IRF6
Type: gene
Organism: dog, domestic
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Protein
Q9QZL7
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: true
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Protein Coding Gene
MGI:1859211 | Irf6
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781881
Age: embryonic day 17.5
Specimen Label: Irf6 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781881
Age: embryonic day 17.5
Specimen Label: Irf6 mutant
Detected: true
Specimen Num: 2
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Publication
28643456 | J:244349
First Author: Kousa YA
Year: 2017
Journal: Dev Dyn
Title: IRF6 expression in basal epithelium partially rescues Irf6 knockout mice.
Volume: 246
Issue: 9
Pages: 670-681
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Publication
29913133 | J:309667
First Author: Kousa YA
Year: 2018
Journal: J Invest Dermatol
Title: IRF6 and AP2A Interaction Regulates Epidermal Development.
Volume: 138
Issue: 12
Pages: 2578-2588
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Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
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Publication
27927890 | J:289168
First Author: Tamasas B
Year: 2017
Journal: J Dent Res
Title: Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model.
Volume: 96
Issue: 3
Pages: 315-322
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Publication
17041603 | J:116077
First Author: Richardson RJ
Year: 2006
Journal: Nat Genet
Title: Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.
Volume: 38
Issue: 11
Pages: 1329-34
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Publication
28732181 | J:255609
First Author: Kousa YA
Year: 2017
Journal: J Dent Res
Title: IRF6 and SPRY4 Signaling Interact in Periderm Development.
Volume: 96
Issue: 11
Pages: 1306-1313
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Publication
28769044 | J:267941
First Author: Fakhouri WD
Year: 2017
Journal: Sci Rep
Title: Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development.
Volume: 7
Issue: 1
Pages: 7129
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Publication
- | J:94918
     
First Author: Schutte B
Year: 2005
Journal: MGI Direct Data Submission
Title: Mice that lack Irf6 exhibit skin, limb and craniofacial abnormalities
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Publication
28645193 | J:246329
First Author: Li C
Year: 2017
Journal: Endocrinology
Title: IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages.
Volume: 158
Issue: 9
Pages: 2837-2847
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Publication
28526834 | J:273515
First Author: Huang R
Year: 2017
Journal: Sci Rep
Title: The Transcription Factor IRF6 Co-Represses PPARγ-Mediated Cytoprotection in Ischemic Cerebrovascular Endothelial Cells.
Volume: 7
Issue: 1
Pages: 2150
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Publication
24442519 | J:209153
First Author: Fakhouri WD
Year: 2014
Journal: Hum Mol Genet
Title: An etiologic regulatory mutation in IRF6 with loss- and gain-of-function effects.
Volume: 23
Issue: 10
Pages: 2711-20
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Publication
18836445 | J:181021
First Author: Rahimov F
Year: 2008
Journal: Nat Genet
Title: Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip.
Volume: 40
Issue: 11
Pages: 1341-7
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Publication
23451037 | J:199408
First Author: Goudy S
Year: 2013
Journal: PLoS One
Title: Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue.
Volume: 8
Issue: 2
Pages: e56270
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Publication
26240017 | J:250738
 
First Author: Ke CY
Year: 2015
Journal: Sci Rep
Title: IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion.
Volume: 5
Pages: 12791
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Publication
22113860 | J:333537
First Author: Fakhouri WD
Year: 2012
Journal: Dev Dyn
Title: MCS9.7 enhancer activity is highly, but not completely, associated with expression of Irf6 and p63.
Volume: 241
Issue: 2
Pages: 340-9
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Publication
27369589 | J:275989
First Author: Chu EY
Year: 2016
Journal: J Dent Res
Title: Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model.
Volume: 95
Issue: 11
Pages: 1265-73
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Publication
31387937 | J:282087
 
First Author: Ke CY
Year: 2019
Journal: Sci Signal
Title: IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion.
Volume: 12
Issue: 593
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Publication
23029012 | J:192000
First Author: Letra A
Year: 2012
Journal: PLoS One
Title: Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate.
Volume: 7
Issue: 9
Pages: e45441
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Publication
21909072 | J:180027
First Author: Restivo G
Year: 2011
Journal: EMBO J
Title: IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes.
Volume: 30
Issue: 22
Pages: 4571-85
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Publication
23406900 | J:194043
First Author: Iwata J
Year: 2013
Journal: Development
Title: Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice.
Volume: 140
Issue: 6
Pages: 1220-30
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Publication
20424327 | J:161459
First Author: Thomason HA
Year: 2010
Journal: J Clin Invest
Title: Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice.
Volume: 120
Issue: 5
Pages: 1561-9
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Publication
19439425 | J:150009
First Author: Richardson RJ
Year: 2009
Journal: Hum Mol Genet
Title: Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence.
Volume: 18
Issue: 14
Pages: 2632-42
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Publication
20424325 | J:161645
First Author: Moretti F
Year: 2010
Journal: J Clin Invest
Title: A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias.
Volume: 120
Issue: 5
Pages: 1570-7
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GXD Expression
GXD Expression
     
Probe: MGI:6781811
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781885
Age: embryonic day 17.5
Specimen Label: Irf6 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6781811
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781885
Age: embryonic day 17.5
Specimen Label: Irf6 mutant
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6781812
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781884
Age: embryonic day 17.5
Specimen Label: Irf6 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6781812
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:6781884
Age: embryonic day 17.5
Specimen Label: Irf6 mutant
Detected: true
Specimen Num: 2
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Publication
18212048 | J:153307
First Author: Bailey CM
Year: 2008
Journal: Mol Cell Biol
Title: Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner.
Volume: 28
Issue: 7
Pages: 2235-43
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Publication
19036739 | J:153386
First Author: Little HJ
Year: 2009
Journal: Hum Mol Genet
Title: Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6.
Volume: 18
Issue: 3
Pages: 535-45
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Publication
28481036 | J:242906
 
First Author: Smith AL
Year: 2017
Journal: Genesis
Title: Generation and characterization of a conditional allele of Interferon Regulatory Factor 6.
Volume: 55
Issue: 7
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Publication
24357509 | J:225262
First Author: Aerts A
Year: 2014
Journal: Am J Med Genet A
Title: Haploinsufficiency of interferon regulatory factor 6 alters brain morphology in the mouse.
Volume: 164A
Issue: 3
Pages: 655-60
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Publication
24777480 | J:214669
First Author: Biggs LC
Year: 2014
Journal: J Cell Sci
Title: Interferon regulatory factor 6 regulates keratinocyte migration.
Volume: 127
Issue: Pt 13
Pages: 2840-8
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Publication
20196077 | J:160190
First Author: Stottmann RW
Year: 2010
Journal: Genesis
Title: Identification of a Van der Woude syndrome mutation in the cleft palate 1 mutant mouse.
Volume: 48
Issue: 5
Pages: 303-8
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Publication
21918538 | J:180634
First Author: Biggs LC
Year: 2012
Journal: J Invest Dermatol
Title: Interferon regulatory factor 6 is necessary, but not sufficient, for keratinocyte differentiation.
Volume: 132
Issue: 1
Pages: 50-8
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Publication
31724286 | J:286595
First Author: Rhea L
Year: 2020
Journal: Dev Dyn
Title: Interferon regulatory factor 6 is required for proper wound healing in vivo.
Volume: 249
Issue: 4
Pages: 509-522
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Publication
27035130 | J:249150
First Author: Joly S
Year: 2016
Journal: PLoS One
Title: Interferon Regulatory Factor 6 Has a Protective Role in the Host Response to Endotoxic Shock.
Volume: 11
Issue: 4
Pages: e0152385
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Publication
23008150 | J:202648
First Author: Leslie EJ
Year: 2012
Journal: Birth Defects Res A Clin Mol Teratol
Title: Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22.
Volume: 94
Issue: 11
Pages: 934-42
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Publication
16245336 | J:108225
First Author: Knight AS
Year: 2006
Journal: Dev Dyn
Title: Developmental expression analysis of the mouse and chick orthologues of IRF6: the gene mutated in Van der Woude syndrome.
Volume: 235
Issue: 5
Pages: 1441-7
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Publication
17041601 | J:115343
First Author: Ingraham CR
Year: 2006
Journal: Nat Genet
Title: Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6).
Volume: 38
Issue: 11
Pages: 1335-40
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Publication
33234718 | J:301551
 
First Author: Carroll SH
Year: 2020
Journal: Development
Title: An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates.
Volume: 147
Issue: 24
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HT Experiment
GSE102020 | The role of IRF6 in salivary gland development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
21982646 | J:178316
First Author: Ferretti E
Year: 2011
Journal: Dev Cell
Title: A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.
Volume: 21
Issue: 4
Pages: 627-41
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Publication
24360809 | J:226218
First Author: Peyrard-Janvid M
Year: 2014
Journal: Am J Hum Genet
Title: Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development.
Volume: 94
Issue: 1
Pages: 23-32
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Publication
31943082 | J:286649
First Author: Hall EG
Year: 2020
Journal: Hum Mol Genet
Title: SPECC1L regulates palate development downstream of IRF6.
Volume: 29
Issue: 5
Pages: 845-858
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Publication
30689861 | J:277917
First Author: Kousa YA
Year: 2019
Journal: Hum Mol Genet
Title: The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.
Volume: 28
Issue: 10
Pages: 1726-1737
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Publication
16780827 | J:112634
First Author: Xu X
Year: 2006
Journal: Dev Biol
Title: Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion.
Volume: 297
Issue: 1
Pages: 238-48
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Publication
25387952 | J:321073
First Author: Mollo MR
Year: 2015
Journal: Exp Dermatol
Title: p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis.
Volume: 24
Issue: 2
Pages: 114-9
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Publication
21574244 | J:174238
First Author: Rorick NK
Year: 2011
Journal: Am J Med Genet A
Title: Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Volume: 155A
Issue: 6
Pages: 1314-21
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Publication
31578523 | J:283325
First Author: Oberbeck N
Year: 2019
Journal: Nature
Title: The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Volume: 574
Issue: 7777
Pages: 249-253
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Publication
30684382 | J:273627
First Author: Thompson J
Year: 2019
Journal: Dev Dyn
Title: A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.
Volume: 248
Issue: 3
Pages: 221-232
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Publication
27302476 | J:234343
First Author: Kawasaki M
Year: 2016
Journal: Dev Dyn
Title: Regional regulation of Filiform tongue papillae development by Ikkα/Irf6.
Volume: 245
Issue: 9
Pages: 937-46
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Protein Coding Gene
MGP_CAROLIEiJ_G0015065 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016719 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1859211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016874 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028297 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015865 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6781886
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6781886
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6470013
Assay Type: RT-PCR
Annotation Date: 2020-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674825
Stage: TS25
Assay Id: MGI:6470037
Age: embryonic day 17.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6470013
Assay Type: RT-PCR
Annotation Date: 2020-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674825
Stage: TS25
Assay Id: MGI:6470037
Age: embryonic day 17.5
Specimen Label: Irf6neo/
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815817
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816621
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3815817
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816621
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6781886
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3815817
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816621
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6781886
Age: postnatal adult
Specimen Label: Sk.Mus
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6781886
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6781886
Age: embryonic day 7.0
Specimen Label: 7 dpc
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6781886
Age: embryonic day 11.0
Specimen Label: 11 dpc
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6781886
Age: embryonic day 15.0
Specimen Label: 15 dpc
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6781886
Age: embryonic day 17.0
Specimen Label: 17 dpc
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6781921
Age: embryonic day 7.0
Specimen Label: 7 DPC
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6781921
Age: embryonic day 11.0
Specimen Label: 11 DPC
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6781801
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6781921
Age: embryonic day 15.0
Specimen Label: 15 DPC
Detected: true
Specimen Num: 4
•
•
•
•
•




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