Cyclic nucleotide-gated cation channel beta-3 (CNGB3, also known as CNG6) is a beta subunit of the cyclic nucleotide-gated (CNG) channel. CNG channels control the influx of Ca2+ and Na+ in response to signal-induced changes of cGMP or cAMP levels. They play a key role in olfactory and visual transduction []. Mutations in the CNGB3 gene have been linked to achromatopsia (rod monochromacy, total colour blindness) [].