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Search results 701 to 800 out of 983 for Braf

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Type Details Score
Publication
25351955 | J:218275
First Author: Ferrari de Andrade L
Year: 2014
Journal: Cancer Res
Title: Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma.
Volume: 74
Issue: 24
Pages: 7298-308
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Publication
22256804 | J:181162
First Author: Su F
Year: 2012
Journal: N Engl J Med
Title: RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Volume: 366
Issue: 3
Pages: 207-15
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Publication
33206716 | J:297542
First Author: Younes ST
Year: 2020
Journal: PLoS One
Title: In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma.
Volume: 15
Issue: 11
Pages: e0242521
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Strain
MGI:6354563 | C57BL/6J-Braf<tm1(flox-V600E)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
24163374 | J:208914
First Author: Faber AC
Year: 2014
Journal: Cancer Discov
Title: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Volume: 4
Issue: 1
Pages: 42-52
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Publication
9799843 | J:50580
First Author: Wojnowski L
Year: 1998
Journal: Mamm Genome
Title: Reduced activity of BRAF protein kinase in hop and hop(hpy) mouse mutants.
Volume: 9
Issue: 11
Pages: 905-6
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Publication
28827320 | J:250257
First Author: Duggan MC
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
Volume: 114
Issue: 36
Pages: 9629-9634
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Publication
17510423 | J:121738
First Author: Ji H
Year: 2007
Journal: Cancer Res
Title: Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Volume: 67
Issue: 10
Pages: 4933-9
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Allele
Braf<em1Smoc> | MGI:7288519
Name: Braf transforming gene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
26248136 | J:232891
First Author: Zhang ZX
Year: 2015
Journal: Biochem Biophys Res Commun
Title: BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1.
Volume: 465
Issue: 2
Pages: 225-31
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Strain
MGI:6770599 | C57BL/6-Braf<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
18974108 | -
First Author: Jones DT
Year: 2008
Journal: Cancer Res
Title: Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas.
Volume: 68
Issue: 21
Pages: 8673-7
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Publication
28910386 | J:249827
First Author: Buffet C
Year: 2017
Journal: PLoS One
Title: DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers.
Volume: 12
Issue: 9
Pages: e0184861
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Allele
Braf<tm1Mmcm> | MGI:3711771
Name: Braf transforming gene; targeted mutation 1, Martin McMahon
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1.1Brum> | MGI:5912238
Name: Braf transforming gene; targeted mutation 1.1, Tilman Brummer
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Braf<tm2Mmcm> | MGI:7448917
Name: Braf transforming gene; targeted mutation 2, Martin McMahon
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, No functional change
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Allele
Braf<tm1.2Brum> | MGI:5912240
 
Name: Braf transforming gene; targeted mutation 1.2, Tilman Brummer
Allele Type: Targeted
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Allele
Braf<+> | MGI:1857578
 
Name: Braf transforming gene; wild type
Allele Type: Not Specified
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Allele
Braf<tm1Cpri> | MGI:3612533
Name: Braf transforming gene; targeted mutation 1, Catrin Pritchard
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, No functional change
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Publication
19363522 | -
First Author: Jones DT
Year: 2009
Journal: Oncogene
Title: Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
Volume: 28
Issue: 20
Pages: 2119-23
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DO Term
DOID:0060585 | Noonan syndrome 7
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DO Term
DOID:0111460 | cardiofaciocutaneous syndrome 1
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Strain
MGI:6474868 | C57BL/6J-Braf<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7491963 | STOCK Braf<tm2Mmcm>/J
Attribute String: mutant stock, targeted mutation
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Allele
Braf<Gt(RRO367)Byg> | MGI:4329116
 
Name: Braf transforming gene; gene trap RRO367, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(RRS254)Byg> | MGI:4330273
 
Name: Braf transforming gene; gene trap RRS254, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(XE282)Byg> | MGI:4124775
 
Name: Braf transforming gene; gene trap XE282, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(XE617)Byg> | MGI:4125983
 
Name: Braf transforming gene; gene trap XE617, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(XN124)Byg> | MGI:4129692
 
Name: Braf transforming gene; gene trap XN124, BayGenomics
Allele Type: Gene trapped
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Strain
MGI:5317166 | B6.129P2(Cg)-Braf<tm1Mmcm>/J
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:6792070 | STOCK Braf<tm1Mmcm>/Cvrk
Attribute String: mutant stock, targeted mutation
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DO Term
DOID:0080550 | Noonan syndrome with multiple lentigines 3
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Publication
16753739 | -
First Author: Lee JH
Year: 2006
Journal: Pathology
Title: BRAF mutation and AKAP9 expression in sporadic papillary thyroid carcinomas.
Volume: 38
Issue: 3
Pages: 201-4
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Allele
Braf<tm1Bbd> | MGI:4946645
Name: Braf transforming gene; targeted mutation 1, Mariano Barbacid
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Hypomorph
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Allele
Braf<tm2.2Urr> | MGI:5512689
Name: Braf transforming gene; targeted mutation 2.2, Urr R Rapp
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<tm1Wds> | MGI:3711006
Name: Braf transforming gene; targeted mutation 1, William D Snider
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<Gt(EUCE00111f02)Hmgu> | MGI:4382681
 
Name: Braf transforming gene; gene trap EUCE00111f02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<Gt(F045D02)Wrst> | MGI:4123655
 
Name: Braf transforming gene; gene trap F045D02, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Braf<tm1.1Tumg> | MGI:7488140
 
Name: Braf transforming gene; targeted mutation 1.1, Yoko Aoki
Allele Type: Targeted
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Allele
Braf<Gt(OST364120)Lex> | MGI:4295037
 
Name: Braf transforming gene; gene trap OST364120, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<tm1e(EUCOMM)Wtsi> | MGI:4820369
Name: Braf transforming gene; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Braf<tm1Tumg> | MGI:5902220
Name: Braf transforming gene; targeted mutation 1, Yoko Aoki
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Braf<Gt(AN0584)Wtsi> | MGI:3864100
 
Name: Braf transforming gene; gene trap AN0584, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<tm1.1Sva> | MGI:3622462
Name: Braf transforming gene; targeted mutation 1.1, Alcino Silva
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<Gt(EUCE0154c11)Hmgu> | MGI:4396439
 
Name: Braf transforming gene; gene trap EUCE0154c11, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<tm2Cpri> | MGI:5440045
Name: Braf transforming gene; targeted mutation 2, Catrin Pritchard
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<em1Gpt> | MGI:7295988
Name: Braf transforming gene; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Braf<em2Cya> | MGI:7582621
Name: Braf transforming gene; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Braf<Gt(AT0126)Wtsi> | MGI:4346783
 
Name: Braf transforming gene; gene trap AT0126, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<tm1a(EUCOMM)Wtsi> | MGI:4820236
Name: Braf transforming gene; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Braf<tm1(ARAF)Urr> | MGI:3664469
 
Name: Braf transforming gene; targeted mutation 1, Ulf R Rapp
Allele Type: Targeted
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Allele
Braf<tm2.1Eyc> | MGI:4888305
Name: Braf transforming gene; targeted mutation 2.1, Alain Eychene
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Braf<em1Cya> | MGI:7582620
Name: Braf transforming gene; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Braf<Gt(OST309428)Lex> | MGI:4274472
 
Name: Braf transforming gene; gene trap OST309428, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(EUCE00115e08)Hmgu> | MGI:4395430
 
Name: Braf transforming gene; gene trap EUCE00115e08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<Gt(CH0627)Wtsi> | MGI:3872006
 
Name: Braf transforming gene; gene trap CH0627, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<tm1.1Wds> | MGI:3711007
Name: Braf transforming gene; targeted mutation 1.1, William D Snider
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<Gt(AY0605)Wtsi> | MGI:3857502
 
Name: Braf transforming gene; gene trap AY0605, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(OST40239)Lex> | MGI:4156812
 
Name: Braf transforming gene; gene trap OST40239, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<tm1Rima> | MGI:4458346
Name: Braf transforming gene; targeted mutation 1, Richard Marais
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1Sva> | MGI:3620008
Name: Braf transforming gene; targeted mutation 1, Alcino J Silva
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<Gt(OST379833)Lex> | MGI:4300482
 
Name: Braf transforming gene; gene trap OST379833, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<tm1Tuv> | MGI:5318063
Name: Braf transforming gene; targeted mutation 1, David A Tuveson
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<Gt(OST60560)Lex> | MGI:4167460
 
Name: Braf transforming gene; gene trap OST60560, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<tm2Urr> | MGI:5512687
Name: Braf transforming gene; targeted mutation 2, Urr R Rapp
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1.1Brd> | MGI:5527388
Name: Braf transforming gene; targeted mutation 1.1, Allan Bradley
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Braf<Gt(AA0135)Wtsi> | MGI:4345318
 
Name: Braf transforming gene; gene trap AA0135, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<tm1Zim> | MGI:1857579
Name: Braf transforming gene; targeted mutation 1, Andreas Zimmer
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<Gt(OST436107)Lex> | MGI:4316537
 
Name: Braf transforming gene; gene trap OST436107, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<tm2.1Urr> | MGI:5512688
Name: Braf transforming gene; targeted mutation 2.1, Urr R Rapp
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<em6Gpt> | MGI:7295989
Name: Braf transforming gene; endonuclease-mediated mutation 6, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Braf<Gt(BA0436)Wtsi> | MGI:3864349
 
Name: Braf transforming gene; gene trap BA0436, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<tm1.1Eyc> | MGI:4888303
Name: Braf transforming gene; targeted mutation 1.1, Alain Eychene
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Braf-rs1<+> | MGI:2430095
   
Name: Braf transforming gene, related sequence 1; wild type
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Publication
23441035 | J:196873
First Author: Ortiz O
Year: 2013
Journal: Genesis
Title: Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in Braf(V637)ER(T2) mice.
Volume: 51
Issue: 6
Pages: 448-55
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Genotype
Genotype
Symbol: Braf/? Tg(TPO-cre)1Shk/?
Background: involves: 129P2/OlaHsd * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
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Publication
32719131 | J:293934
First Author: Niitsu Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with KRAS and BRAF mutations.
Volume: 117
Issue: 32
Pages: 19435-19445
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Genotype
Genotype
Symbol: Braf/Braf<+> Tg(Tg-cre/ERT2)#Mmcm/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+> Tg(TPO-cre/ERT2)1139Tyj/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Tg(TPO-cre)1Shk/?
Background: involves: 129P2/OlaHsd * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Tg(Itgax-cre)1-1Reiz/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Strain
MGI:4947063 | B6.129-Braf<tm1Bbd>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5499508 | STOCK Braf<tm1Bbd>/Cnbc
Attribute String: targeted mutation, mutant stock
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Strain
MGI:6147230 | STOCK Braf<tm1.1Tumg>/TumgRbrc
Attribute String: targeted mutation, mutant stock
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Strain
MGI:6147229 | B6.Cg-Braf<tm1Tumg>/Rbrc
Attribute String: mutant strain, targeted mutation, congenic
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Strain
MGI:6147303 | C.Cg-Braf<tm1Tumg>/TumgRbrc
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:6147302 | 129.Cg-Braf<tm1Tumg>
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:7587984 | C57BL/6J-Braf<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7590796 | C57BL/6J-Braf<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:3699356 | 129-Braf<tm1Sva>/J
Attribute String: mutant strain, targeted mutation, coisogenic
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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