Pre-rRNA-processing protein Esf1 is required for the biogenesis of 18S rRNA in Saccharomyces cerevisiae. It has a role in early pre-rRNA processing because it associates with U3 and U14 snoRNAs but not the SSU processome []. Homologues are found in other fungi, animals and plants.
This entry represents a domain found in ESF1 (Embryo surrounding factor 1), a protein found in Arabidopsis thaliana and other brassicaceae. Maternally contributed central cell ESF1 peptides play an important role in suspensor formation and pro-embryo development. The biological activity of ESF1 depends on structural topology, which is stabilized by disulfide bonds [].
