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Search results 2601 to 2700 out of 3066 for Lepr

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Type Details Score
Publication
33545051 | J:303733
First Author: Liu K
Year: 2021
Journal: Cell Metab
Title: Metabolic stress drives sympathetic neuropathy within the liver.
Volume: 33
Issue: 3
Pages: 666-675.e4
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29158088 | J:270556
First Author: Yamamoto K
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Interplay of adipocyte and hepatocyte: Leptin upregulates hepcidin.
Volume: 495
Issue: 1
Pages: 1548-1554
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Publication
25003192 | J:213849
First Author: Lu Y
Year: 2014
Journal: J Clin Invest
Title: Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARĪ±.
Volume: 124
Issue: 8
Pages: 3501-13
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Publication
31729980 | J:292453
First Author: Wang L
Year: 2019
Journal: Lipids Health Dis
Title: FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c.
Volume: 18
Issue: 1
Pages: 197
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Publication
8603777 | J:32265
First Author: Schwartz MW
Year: 1996
Journal: Diabetes
Title: Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.
Volume: 45
Issue: 4
Pages: 531-5
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Publication
25980347 | J:226133
First Author: Ottaway N
Year: 2015
Journal: Cell Metab
Title: Diet-induced obese mice retain endogenous leptin action.
Volume: 21
Issue: 6
Pages: 877-82
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Publication
19955656 | J:156776
First Author: Wueest S
Year: 2010
Journal: J Clin Invest
Title: Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.
Volume: 120
Issue: 1
Pages: 191-202
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Publication
21441927 | J:176266
First Author: Jordan SD
Year: 2011
Journal: Nat Cell Biol
Title: Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.
Volume: 13
Issue: 4
Pages: 434-46
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Publication
19628573 | J:157328
First Author: Villanueva EC
Year: 2009
Journal: Endocrinology
Title: Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status.
Volume: 150
Issue: 10
Pages: 4541-51
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Publication
18451994 | J:137683
First Author: Koch L
Year: 2008
Journal: J Clin Invest
Title: Central insulin action regulates peripheral glucose and fat metabolism in mice.
Volume: 118
Issue: 6
Pages: 2132-47
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Publication
30785802 | J:292059
First Author: Wang M
Year: 2019
Journal: FASEB J
Title: High glucose-induced ubiquitination of G6PD leads to the injury of podocytes.
Volume: 33
Issue: 5
Pages: 6296-6310
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Publication
24823376 | J:213582
First Author: Ono N
Year: 2014
Journal: Dev Cell
Title: Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage.
Volume: 29
Issue: 3
Pages: 330-9
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Publication
15820311 | J:97535
First Author: Yaguchi H
Year: 2005
Journal: Genomics
Title: Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL.
Volume: 85
Issue: 5
Pages: 591-9
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Publication
21521693 | J:174820
First Author: Flach RJ
Year: 2011
Journal: J Biol Chem
Title: Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27.
Volume: 286
Issue: 25
Pages: 22195-202
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Publication
23776077 | J:202289
First Author: Pinho S
Year: 2013
Journal: J Exp Med
Title: PDGFRĪ± and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.
Volume: 210
Issue: 7
Pages: 1351-67
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Publication
28508891 | J:250322
 
First Author: Roelofs AJ
Year: 2017
Journal: Nat Commun
Title: Joint morphogenetic cells in the adult mammalian synovium.
Volume: 8
Pages: 15040
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Publication
26441236 | J:232746
First Author: Pedersen KB
Year: 2015
Journal: Endocrinology
Title: Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice.
Volume: 156
Issue: 12
Pages: 4411-25
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Publication
22560222 | J:184780
First Author: Sadagurski M
Year: 2012
Journal: Cell Metab
Title: IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action.
Volume: 15
Issue: 5
Pages: 703-12
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Publication
19745193 | J:177975
First Author: Shore SA
Year: 2009
Journal: J Appl Physiol (1985)
Title: Pulmonary responses to subacute ozone exposure in obese vs. lean mice.
Volume: 107
Issue: 5
Pages: 1445-52
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27518562 | J:236082
First Author: Garcƭa-CƔceres C
Year: 2016
Journal: Cell
Title: Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
Volume: 166
Issue: 4
Pages: 867-880
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Publication
12651605 | J:82491
First Author: Wendt TM
Year: 2003
Journal: Am J Pathol
Title: RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.
Volume: 162
Issue: 4
Pages: 1123-37
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Publication
21940783 | J:189473
First Author: Howard AC
Year: 2011
Journal: Diabetes
Title: A novel cellular defect in diabetes: membrane repair failure.
Volume: 60
Issue: 11
Pages: 3034-43
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Publication
32158758 | J:292548
 
First Author: Burr SD
Year: 2020
Journal: Front Cell Dev Biol
Title: The Impact of Diabetic Conditions and AGE/RAGE Signaling on Cardiac Fibroblast Migration.
Volume: 8
Pages: 112
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9568684 | J:46631
First Author: Baskin DG
Year: 1998
Journal: Diabetes
Title: Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting.
Volume: 47
Issue: 4
Pages: 538-43
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Publication
34042586 | J:325529
   
First Author: Siemian JN
Year: 2021
Journal: Elife
Title: An excitatory lateral hypothalamic circuit orchestrating pain behaviors in mice.
Volume: 10
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24760864 | J:210610
First Author: Martin C
Year: 2014
Journal: J Neurosci
Title: Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone.
Volume: 34
Issue: 17
Pages: 6047-56
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26441241 | J:232827
First Author: SaĆ©z-LĆ³pez C
Year: 2015
Journal: Endocrinology
Title: SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development.
Volume: 156
Issue: 12
Pages: 4571-81
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Publication
30996080 | J:273800
 
First Author: Peng S
Year: 2019
Journal: Sci Transl Med
Title: Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Volume: 11
Issue: 488
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Publication
18971923 | J:162711
First Author: Ijaz A
Year: 2009
Journal: Kidney Int
Title: Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes.
Volume: 75
Issue: 4
Pages: 381-8
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Publication
27412556 | J:240830
 
First Author: Jang H
Year: 2016
Journal: Nat Commun
Title: SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding.
Volume: 7
Pages: 12180
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Publication
27064284 | J:234938
First Author: Stratigopoulos G
Year: 2016
Journal: J Clin Invest
Title: Hypomorphism of Fto and Rpgrip1l causes obesity in mice.
Volume: 126
Issue: 5
Pages: 1897-910
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Publication
25264246 | J:215526
First Author: Kim-Muller JY
Year: 2014
Journal: Cell Metab
Title: Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice.
Volume: 20
Issue: 4
Pages: 593-602
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Publication
21098489 | J:168491
First Author: Wei X
Year: 2011
Journal: J Biol Chem
Title: De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
Volume: 286
Issue: 4
Pages: 2933-45
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Publication
31738412 | J:313801
First Author: Samidurai A
Year: 2020
Journal: Cardiovasc Res
Title: STAT3-miR-17/20 signalling axis plays a critical role in attenuating myocardial infarction following rapamycin treatment in diabetic mice.
Volume: 116
Issue: 13
Pages: 2103-2115
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Publication
33456576 | J:331219
First Author: Sheng J
Year: 2021
Journal: Theranostics
Title: Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.
Volume: 11
Issue: 6
Pages: 2845-2859
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Publication
30002389 | J:268171
First Author: Ono H
Year: 2018
Journal: Sci Rep
Title: Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy.
Volume: 8
Issue: 1
Pages: 10548
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Publication
29222368 | J:258617
First Author: Sun SF
Year: 2018
Journal: Diabetes
Title: Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b.
Volume: 67
Issue: 4
Pages: 731-744
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Publication
31150422 | J:276464
First Author: Sakurai A
Year: 2019
Journal: PLoS One
Title: Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy.
Volume: 14
Issue: 5
Pages: e0216788
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Publication
31624141 | J:287848
First Author: Tan SM
Year: 2020
Journal: Diabetes
Title: Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.
Volume: 69
Issue: 1
Pages: 83-98
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Publication
30293775 | J:272050
First Author: King BC
Year: 2019
Journal: Cell Metab
Title: Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents Ī² Cell Death via ATG16L1 Interaction and Autophagy Regulation.
Volume: 29
Issue: 1
Pages: 202-210.e6
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Publication
17595213 | J:125421
First Author: Iwakura H
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Effects of ghrelin administration on decreased growth hormone status in obese animals.
Volume: 293
Issue: 3
Pages: E819-25
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Publication
25249008 | J:324511
First Author: Mohamed R
Year: 2014
Journal: J Mol Med (Berl)
Title: Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice.
Volume: 92
Issue: 12
Pages: 1245-56
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Publication
20130530 | J:184276
First Author: Nicholas SB
Year: 2010
Journal: Kidney Int
Title: Critical role for osteopontin in diabetic nephropathy.
Volume: 77
Issue: 7
Pages: 588-600
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Publication
24003152 | J:201158
First Author: Hu Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Pathogenic role of diabetes-induced PPAR-Ī± down-regulation in microvascular dysfunction.
Volume: 110
Issue: 38
Pages: 15401-6
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Publication
3553324 | J:32752
First Author: Leiter EH
Year: 1987
Journal: J Immunol
Title: Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Volume: 138
Issue: 10
Pages: 3224-9
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Publication
37783236 | J:343603
 
First Author: Nagy N
Year: 2023
Journal: Matrix Biol
Title: Inhibition of hyaluronan synthesis prevents Ī²-cell loss in obesity-associated type 2 diabetes.
Volume: 123
Pages: 34-47
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Publication
20813969 | J:165434
First Author: Schatteman GC
Year: 2010
Journal: Am J Pathol
Title: Lin- cells mediate tissue repair by regulating MCP-1/CCL-2.
Volume: 177
Issue: 4
Pages: 2002-10
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Publication
36030260 | J:327972
First Author: Al-Dabet MM
Year: 2022
Journal: Nat Commun
Title: Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
Volume: 13
Issue: 1
Pages: 5062
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Publication
21270276 | J:169783
First Author: Figler RA
Year: 2011
Journal: Diabetes
Title: Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.
Volume: 60
Issue: 2
Pages: 669-79
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Publication
21586559 | J:174883
First Author: Peier AM
Year: 2011
Journal: Endocrinology
Title: Effects of peripherally administered neuromedin U on energy and glucose homeostasis.
Volume: 152
Issue: 7
Pages: 2644-54
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Publication
37433344 | J:341052
 
First Author: Hu T
Year: 2023
Journal: Metabolism
Title: PRDM16 exerts critical role in myocardial metabolism and energetics in type 2 diabetes induced cardiomyopathy.
Volume: 146
Pages: 155658
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Publication
37224018 | J:337914
First Author: Jin S
Year: 2023
Journal: Cell Rep
Title: Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis.
Volume: 42
Issue: 6
Pages: 112550
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Publication
25098764 | J:224579
 
First Author: Chuang HC
Year: 2014
Journal: Nat Commun
Title: HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance.
Volume: 5
Pages: 4602
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Publication
16043866 | J:103714
First Author: Barile GR
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: The RAGE axis in early diabetic retinopathy.
Volume: 46
Issue: 8
Pages: 2916-24
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Publication
27932386 | J:247019
First Author: Liu B
Year: 2017
Journal: Diabetes
Title: Aberrant Expression of FBXO2 Disrupts Glucose Homeostasis Through Ubiquitin-Mediated Degradation of Insulin Receptor in Obese Mice.
Volume: 66
Issue: 3
Pages: 689-698
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Publication
22326951 | J:184484
First Author: Battiprolu PK
Year: 2012
Journal: J Clin Invest
Title: Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.
Volume: 122
Issue: 3
Pages: 1109-18
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Publication
30449684 | J:272008
First Author: Neinast MD
Year: 2019
Journal: Cell Metab
Title: Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids.
Volume: 29
Issue: 2
Pages: 417-429.e4
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Publication
24037094 | J:202020
First Author: Wei K
Year: 2013
Journal: Nat Med
Title: A liver Hif-2Ī±-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
Volume: 19
Issue: 10
Pages: 1331-1337
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Publication
22147007 | J:181743
First Author: Zhang K
Year: 2012
Journal: Endocrinology
Title: Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice.
Volume: 153
Issue: 2
Pages: 631-46
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Publication
32005828 | J:285483
First Author: Pradas-Juni M
Year: 2020
Journal: Nat Commun
Title: A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Volume: 11
Issue: 1
Pages: 644
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Publication
29610518 | J:261936
First Author: Meakin PJ
Year: 2018
Journal: Nat Commun
Title: The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
Volume: 9
Issue: 1
Pages: 1306
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23028378 | J:190447
First Author: Oh KJ
Year: 2012
Journal: PLoS Genet
Title: TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver.
Volume: 8
Issue: 9
Pages: e1002986
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Publication
17827403 | J:132424
First Author: Koh EH
Year: 2007
Journal: Diabetes
Title: Essential role of mitochondrial function in adiponectin synthesis in adipocytes.
Volume: 56
Issue: 12
Pages: 2973-81
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Publication
29717156 | J:262756
First Author: Umino H
Year: 2018
Journal: Sci Rep
Title: High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection.
Volume: 8
Issue: 1
Pages: 6791
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Publication
28576832 | J:244054
First Author: Cao J
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice.
Volume: 313
Issue: 2
Pages: H368-H380
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Publication
18065517 | J:132456
First Author: Han KL
Year: 2008
Journal: Diabetes
Title: Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
Volume: 57
Issue: 3
Pages: 737-45
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22037186 | J:181575
First Author: Velmurugan GV
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels.
Volume: 302
Issue: 1
Pages: H124-34
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Publication
30974318 | J:291683
 
First Author: Kim DH
Year: 2019
Journal: Redox Biol
Title: FoxO6-mediated IL-1Ī² induces hepatic insulin resistance and age-related inflammation via the TF/PAR2 pathway in aging and diabetic mice.
Volume: 24
Pages: 101184
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Publication
24486509 | J:210088
First Author: Kassan M
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice.
Volume: 306
Issue: 7
Pages: H972-80
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Publication
30397232 | J:269799
First Author: Oba S
Year: 2018
Journal: Sci Rep
Title: Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells.
Volume: 8
Issue: 1
Pages: 16338
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Publication
32708887 | J:304114
 
First Author: Park SY
Year: 2020
Journal: Molecules
Title: Silk Fibroin Promotes the Regeneration of Pancreatic Ī²-Cells in the C57BL/KsJ-Leprdb/db Mouse.
Volume: 25
Issue: 14
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Publication
22904306 | J:189913
First Author: Shibata S
Year: 2012
Journal: J Immunol
Title: Adiponectin regulates cutaneous wound healing by promoting keratinocyte proliferation and migration via the ERK signaling pathway.
Volume: 189
Issue: 6
Pages: 3231-41
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Publication
22086159 | J:181806
First Author: Ka SM
Year: 2012
Journal: Diabetologia
Title: Kidney-targeting Smad7 gene transfer inhibits renal TGF-Ī²/MAD homologue (SMAD) and nuclear factor ĪŗB (NF-ĪŗB) signalling pathways, and improves diabetic nephropathy in mice.
Volume: 55
Issue: 2
Pages: 509-19
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20601111 | J:165456
First Author: Akasaka Y
Year: 2010
Journal: Biochim Biophys Acta
Title: Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor.
Volume: 1801
Issue: 10
Pages: 1115-22
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Publication
25046864 | J:218484
First Author: Gao P
Year: 2014
Journal: Biochim Biophys Acta
Title: Nrf2 ameliorates diabetic nephropathy progression by transcriptional repression of TGFĪ²1 through interactions with c-Jun and SP1.
Volume: 1839
Issue: 11
Pages: 1110-20
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Publication
21081500 | J:268787
First Author: Im SS
Year: 2011
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor {alpha} is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expression in fasting and db/db Mice.
Volume: 286
Issue: 2
Pages: 1157-64
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Publication
34913989 | J:322738
First Author: Yang S
Year: 2022
Journal: Diabetologia
Title: MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway.
Volume: 65
Issue: 3
Pages: 563-581
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Publication
30135249 | J:266281
 
First Author: Mazor R
Year: 2018
Journal: Sci Transl Med
Title: Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice.
Volume: 10
Issue: 455
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Publication
27188441 | J:259060
First Author: Xiao F
Year: 2016
Journal: Sci Signal
Title: BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism.
Volume: 9
Issue: 428
Pages: ra50
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23836031 | J:202248
First Author: O'Neill CM
Year: 2013
Journal: Endocrinology
Title: Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.
Volume: 154
Issue: 9
Pages: 3077-88
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Publication
26647385 | J:246081
First Author: Soares MA
Year: 2016
Journal: Diabetes
Title: Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.
Volume: 65
Issue: 3
Pages: 633-46
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Publication
21558549 | J:182059
First Author: Harrod JS
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Altered contribution of RhoA/Rho kinase signaling in contractile activity of myometrium in leptin receptor-deficient mice.
Volume: 301
Issue: 2
Pages: E362-9
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Publication
23504315 | J:198384
First Author: Chen J
Year: 2013
Journal: J Biol Chem
Title: LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice.
Volume: 288
Issue: 17
Pages: 12395-405
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Publication
24361011 | J:210553
First Author: Rasmussen BA
Year: 2014
Journal: Cell Metab
Title: Jejunal leptin-PI3K signaling lowers glucose production.
Volume: 19
Issue: 1
Pages: 155-61
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Publication
20814014 | J:182099
First Author: Zhang H
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
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