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Search results 101 to 122 out of 122 for Tnrc6b

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Type Details Score
Protein
Q05CE3
Organism: Mus musculus/domesticus
Length: 1017  
Fragment?: true
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Protein Domain
IPR034927 | TNRC6C_RRM
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of trinucleotide repeat-containing gene 6C protein (TNRC6C).Mammals have three GW182 paralogues, TNRC6A, TNRC6B and TNRC6C. They interact directly with Argonaute (Ago) proteins and function downstream as effectors mediating mRNA repression. They repress mRNAs by recruiting the CCR4-NOT complex to the mRNA. They contain the N-terminal effector domain (NED), the middle Q-rich region, and the C-terminal effector domain (CED) containing the poly(A) binding protein (PABP)-interacting motif 2 (PAM2) and the RNA-recognition motif (RRM) [].
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Protein Domain
IPR033499 | TNRC6C
Type: Family
Description: Mammals have three GW182 paralogues, TNRC6A, TNRC6B and TNRC6C. They interact directly with Argonaute (Ago) proteins and function downstream as effectors mediating mRNA repression. They repress mRNAs by recruiting the CCR4-NOT complex to the mRNA. They contain the N-terminal effector domain (NED), the middle Q-rich region, and the C-terminal effector domain (CED) containing the poly(A) binding protein (PABP)-interacting motif 2 (PAM2) and the RNA-recognition motif (RRM) [].This entry represents TNRC6C from vertebrates. Similar to TNRC6A/B, TNRC6C is essential for efficient miRNA repression [].
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Protein Domain
IPR033501 | TNRC6A
Type: Family
Description: Mammals have three GW182 paralogues, TNRC6A, TNRC6B and TNRC6C. They interact directly with Argonaute (Ago) proteins and function downstream as effectors mediating mRNA repression. They repress mRNAs by recruiting the CCR4-NOT complex to the mRNA. They contain the N-terminal effector domain (NED), the middle Q-rich region, and the C-terminal effector domain (CED) containing the poly(A) binding protein (PABP)-interacting motif 2 (PAM2) and the RNA-recognition motif (RRM) [].This entry represents TNRC6A from vertebrates. Similar to TNRC6B/C, TNRC6A is essential for efficient miRNA repression [].
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Protein
Q8BNF0
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: true
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Protein Domain
IPR034924 | TNRC6A_RRM
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of the GW182 autoantigen, also termed trinucleotide repeat-containing gene 6A protein (TNRC6A).Mammals have three GW182 paralogues, TNRC6A, TNRC6B and TNRC6C. They interact directly with Argonaute (Ago) proteins and function downstream as effectors mediating mRNA repression. They repress mRNAs by recruiting the CCR4-NOT complex to the mRNA. They contain the N-terminal effector domain (NED), the middle Q-rich region, and the C-terminal effector domain (CED) containing the poly(A) binding protein (PABP)-interacting motif 2 (PAM2) and the RNA-recognition motif (RRM) [].
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Publication
24142921 | J:218363
First Author: Wolf L
Year: 2013
Journal: G3 (Bethesda)
Title: Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.
Volume: 3
Issue: 12
Pages: 2239-55
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Protein
Q3UHK8
Organism: Mus musculus/domesticus
Length: 1896  
Fragment?: false
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Protein
A0A0U1RQ65
Organism: Mus musculus/domesticus
Length: 1398  
Fragment?: true
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Protein
Q8BWM2
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: true
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Protein
Q3UQ45
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: true
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Protein
Q99JR3
Organism: Mus musculus/domesticus
Length: 661  
Fragment?: true
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Protein
Q3UUG8
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: true
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Protein
Q8BXM6
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
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Protein
Q3UHC0
Organism: Mus musculus/domesticus
Length: 1690  
Fragment?: false
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Protein
B7ZC94
Organism: Mus musculus/domesticus
Length: 1732  
Fragment?: true
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Protein
B1ATC3
Organism: Mus musculus/domesticus
Length: 1900  
Fragment?: false
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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