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Search results 1 to 100 out of 171 for Ifih1

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Category: Publication
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Type Details Score
Publication
24995871 | J:230149
First Author: Oda H
Year: 2014
Journal: Am J Hum Genet
Title: Aicardi-Goutières syndrome is caused by IFIH1 mutations.
Volume: 95
Issue: 1
Pages: 121-5
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Publication
25591872 | J:246937
First Author: Lincez PJ
Year: 2015
Journal: Diabetes
Title: Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes.
Volume: 64
Issue: 6
Pages: 2184-93
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Publication
22205024 | J:180757
First Author: Crampton SP
Year: 2012
Journal: J Immunol
Title: Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity.
Volume: 188
Issue: 3
Pages: 1451-9
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Publication
28553952 | J:257959
First Author: Gorman JA
Year: 2017
Journal: Nat Immunol
Title: The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Volume: 18
Issue: 7
Pages: 744-752
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Publication
28851763 | J:249050
First Author: Dou Y
Year: 2017
Journal: EMBO J
Title: The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation.
Volume: 36
Issue: 18
Pages: 2742-2757
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Publication
36512407 | J:339647
 
First Author: Blum SI
Year: 2023
Journal: JCI Insight
Title: MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance.
Volume: 8
Issue: 2
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Publication
35168003 | J:324284
 
First Author: Ohto T
Year: 2022
Journal: J Autoimmun
Title: Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis.
Volume: 127
Pages: 102794
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Publication
31366715 | J:278687
First Author: Soda N
Year: 2019
Journal: J Immunol
Title: Singleton-Merten Syndrome-like Skeletal Abnormalities in Mice with Constitutively Activated MDA5.
Volume: 203
Issue: 5
Pages: 1356-1368
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Publication
16625202 | J:137522
First Author: Kato H
Year: 2006
Journal: Nature
Title: Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Volume: 441
Issue: 7089
Pages: 101-5
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Publication
31956894 | J:292357
First Author: Bajad P
Year: 2020
Journal: Nucleic Acids Res
Title: An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.
Volume: 48
Issue: 6
Pages: 3286-3303
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Publication
33165593 | J:300370
     
First Author: Onizawa H
Year: 2020
Journal: Int Immunol
Title: Aicardi-Goutières syndrome-like encephalitis in mutant mice with constitutively active MDA5.
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Publication
28874170 | J:317546
First Author: Heraud-Farlow JE
Year: 2017
Journal: Genome Biol
Title: Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.
Volume: 18
Issue: 1
Pages: 166
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Publication
12015121 | J:76465
First Author: Kovacsovics M
Year: 2002
Journal: Curr Biol
Title: Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation.
Volume: 12
Issue: 10
Pages: 838-43
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Publication
21217758 | J:168254
First Author: Züst R
Year: 2011
Journal: Nat Immunol
Title: Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.
Volume: 12
Issue: 2
Pages: 137-43
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Publication
22090123 | J:179386
First Author: Jin YH
Year: 2012
Journal: J Virol
Title: Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease.
Volume: 86
Issue: 3
Pages: 1531-43
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Publication
20107606 | J:162177
First Author: Gitlin L
Year: 2010
Journal: PLoS Pathog
Title: Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo.
Volume: 6
Issue: 1
Pages: e1000734
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Publication
26423942 | J:227926
First Author: Zalinger ZB
Year: 2015
Journal: J Virol
Title: MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.
Volume: 89
Issue: 24
Pages: 12330-40
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Publication
18941247 | J:140714
First Author: Tamassia N
Year: 2008
Journal: J Immunol
Title: Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils.
Volume: 181
Issue: 9
Pages: 6563-73
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Publication
33767151 | J:340261
First Author: Brown MC
Year: 2021
Journal: Nat Commun
Title: Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling.
Volume: 12
Issue: 1
Pages: 1858
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Publication
36122455 | J:329992
 
First Author: Lee S
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Attenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model.
Volume: 629
Pages: 171-175
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Publication
23328395 | J:193402
First Author: Motz C
Year: 2013
Journal: Science
Title: Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Volume: 339
Issue: 6120
Pages: 690-3
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Publication
19036857 | J:147226
First Author: De Miranda J
Year: 2009
Journal: FASEB J
Title: Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5.
Volume: 23
Issue: 4
Pages: 1064-71
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Publication
23090998 | J:191237
First Author: Berke IC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: MDA5 assembles into a polar helical filament on dsRNA.
Volume: 109
Issue: 45
Pages: 18437-41
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Publication
24474800 | J:206642
First Author: Wu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality.
Volume: 111
Issue: 4
Pages: E511-20
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Publication
34482560 | J:335378
First Author: Zhang X
Year: 2022
Journal: Hepatology
Title: Melanoma differentiation-Associated gene 5 protects against NASH in mice.
Volume: 75
Issue: 4
Pages: 924-938
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Publication
- | J:77433
   
First Author: Kang DC
Year: 2002
Journal: GenBank Submission
Title: Mus musculus strain C57BL/6J melanoma differentiation associated gene 5-like protein mRNA, complete cds
Pages: AF374384
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Publication
- | J:74829
   
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, simialr to RIKEN cDNA 9130009C22 gene, clone IMAGE: 3990931, mRNA, partial cds
Pages: BC019605
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Publication
21187438 | J:168914
First Author: Broquet AH
Year: 2011
Journal: J Immunol
Title: RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.
Volume: 186
Issue: 3
Pages: 1618-26
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Publication
28031478 | J:240099
First Author: Lang X
Year: 2017
Journal: J Exp Med
Title: TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
Volume: 214
Issue: 2
Pages: 459-473
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Publication
28848065 | J:254366
First Author: Kasumba DM
Year: 2017
Journal: J Immunol
Title: A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses.
Volume: 199
Issue: 7
Pages: 2460-2474
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Publication
28250012 | J:241587
First Author: Hu MM
Year: 2017
Journal: J Exp Med
Title: Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5.
Volume: 214
Issue: 4
Pages: 973-989
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Publication
23966390 | J:310254
First Author: Lazear HM
Year: 2013
Journal: J Virol
Title: Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.
Volume: 87
Issue: 21
Pages: 11401-15
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Publication
25451939 | J:218760
First Author: Kitai Y
Year: 2015
Journal: J Biol Chem
Title: Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
Volume: 290
Issue: 2
Pages: 1269-80
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Publication
22314235 | J:182522
First Author: Berke IC
Year: 2012
Journal: EMBO J
Title: MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA.
Volume: 31
Issue: 7
Pages: 1714-26
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Publication
30361393 | J:269483
 
First Author: Nakahama T
Year: 2018
Journal: EMBO Rep
Title: ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity.
Volume: 19
Issue: 12
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Publication
29723194 | J:262046
First Author: Harris ML
Year: 2018
Journal: PLoS Biol
Title: A direct link between MITF, innate immunity, and hair graying.
Volume: 16
Issue: 5
Pages: e2003648
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Publication
38128529 | J:344303
First Author: Knebel UE
Year: 2024
Journal: Cell Metab
Title: Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes.
Volume: 36
Issue: 1
Pages: 48-61.e6
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Publication
34969816 | J:320956
 
First Author: Guo X
Year: 2022
Journal: Life Sci Alliance
Title: ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway.
Volume: 5
Issue: 3
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Publication
36975179 | J:338600
First Author: Liang Z
Year: 2023
Journal: EMBO Rep
Title: The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.
Volume: 24
Issue: 5
Pages: e55835
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Publication
32396862 | J:328612
First Author: Guallar D
Year: 2020
Journal: Cell Stem Cell
Title: ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Volume: 27
Issue: 2
Pages: 300-314.e11
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Publication
32251420 | J:292942
First Author: Zhong X
Year: 2020
Journal: PLoS Pathog
Title: ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response.
Volume: 16
Issue: 4
Pages: e1008457
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Publication
23926323 | J:205789
First Author: Lu HL
Year: 2013
Journal: J Immunol
Title: Melanoma differentiation-associated gene 5 senses hepatitis B virus and activates innate immune signaling to suppress virus replication.
Volume: 191
Issue: 6
Pages: 3264-76
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Publication
18591409 | J:137451
First Author: Kato H
Year: 2008
Journal: J Exp Med
Title: Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5.
Volume: 205
Issue: 7
Pages: 1601-10
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Publication
26275108 | J:226177
First Author: Liddicoat BJ
Year: 2015
Journal: Science
Title: RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
Volume: 349
Issue: 6252
Pages: 1115-20
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Publication
34772697 | J:317182
     
First Author: Inoue M
Year: 2021
Journal: J Immunol
Title: An Aicardi-Goutières Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice.
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Publication
34525338 | J:323650
First Author: Nakahama T
Year: 2021
Journal: Immunity
Title: Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy.
Volume: 54
Issue: 9
Pages: 1976-1988.e7
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Publication
20164430 | J:160108
First Author: Wang Y
Year: 2010
Journal: J Immunol
Title: Cutting edge: polyinosinic:polycytidylic acid boosts the generation of memory CD8 T cells through melanoma differentiation-associated protein 5 expressed in stromal cells.
Volume: 184
Issue: 6
Pages: 2751-5
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Publication
18636103 | J:162720
First Author: McCartney SA
Year: 2008
Journal: PLoS Pathog
Title: MDA-5 recognition of a murine norovirus.
Volume: 4
Issue: 7
Pages: e1000108
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Publication
21637773 | J:176090
First Author: Wang Q
Year: 2011
Journal: PLoS Pathog
Title: MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.
Volume: 7
Issue: 5
Pages: e1002070
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Publication
21242525 | J:169151
First Author: Jelinek I
Year: 2011
Journal: J Immunol
Title: TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection.
Volume: 186
Issue: 4
Pages: 2422-9
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Publication
23499489 | J:195116
First Author: Wies E
Year: 2013
Journal: Immunity
Title: Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.
Volume: 38
Issue: 3
Pages: 437-49
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Publication
28484023 | J:242293
First Author: Deng X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages.
Volume: 114
Issue: 21
Pages: E4251-E4260
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Publication
31067281 | J:275459
First Author: Veazey JM
Year: 2019
Journal: PLoS One
Title: Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.
Volume: 14
Issue: 5
Pages: e0216056
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Publication
19850889 | J:154665
First Author: Flür K
Year: 2009
Journal: Am J Pathol
Title: Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5: Implications for viral infection-associated glomerulonephritis.
Volume: 175
Issue: 5
Pages: 2014-22
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Publication
25119032 | J:217083
First Author: Goubau D
Year: 2014
Journal: Nature
Title: Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates.
Volume: 514
Issue: 7522
Pages: 372-375
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Publication
25012502 | J:230138
First Author: Duewell P
Year: 2014
Journal: Cell Death Differ
Title: RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells.
Volume: 21
Issue: 12
Pages: 1825-37
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Publication
17942531 | J:183219
First Author: Loo YM
Year: 2008
Journal: J Virol
Title: Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.
Volume: 82
Issue: 1
Pages: 335-45
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Publication
20080593 | J:156867
First Author: Satoh T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.
Volume: 107
Issue: 4
Pages: 1512-7
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Publication
29117565 | J:255265
First Author: Zhao C
Year: 2017
Journal: Cell Rep
Title: The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I.
Volume: 21
Issue: 6
Pages: 1613-1623
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Publication
33087405 | J:300722
First Author: Wang X
Year: 2020
Journal: J Immunol
Title: MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.
Volume: 205
Issue: 11
Pages: 3058-3070
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Publication
24530055 | J:209917
First Author: Funabiki M
Year: 2014
Journal: Immunity
Title: Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
Volume: 40
Issue: 2
Pages: 199-212
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Publication
37797622 | J:342174
First Author: Hu SB
Year: 2023
Journal: Mol Cell
Title: ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.
Volume: 83
Issue: 21
Pages: 3869-3884.e7
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Publication
19966212 | J:159428
First Author: Anz D
Year: 2010
Journal: J Immunol
Title: Immunostimulatory RNA blocks suppression by regulatory T cells.
Volume: 184
Issue: 2
Pages: 939-46
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Publication
19414755 | J:148244
First Author: Anz D
Year: 2009
Journal: J Immunol
Title: Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.
Volume: 182
Issue: 10
Pages: 6044-50
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Publication
34253898 | J:337400
First Author: Clapes T
Year: 2021
Journal: Nat Cell Biol
Title: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Volume: 23
Issue: 7
Pages: 704-717
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Publication
23966395 | J:310263
First Author: Errett JS
Year: 2013
Journal: J Virol
Title: The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection.
Volume: 87
Issue: 21
Pages: 11416-25
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Publication
20943997 | J:165633
First Author: Gibbert K
Year: 2010
Journal: J Immunol
Title: Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.
Volume: 185
Issue: 10
Pages: 6179-89
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Publication
16714379 | J:110201
First Author: Gitlin L
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus.
Volume: 103
Issue: 22
Pages: 8459-64
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Publication
30811246 | J:277806
First Author: Shaheen ZR
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA.
Volume: 316
Issue: 5
Pages: R525-R534
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Publication
25758257 | J:230911
First Author: Kozaki T
Year: 2015
Journal: Int Immunol
Title: Role of zinc-finger anti-viral protein in host defense against Sindbis virus.
Volume: 27
Issue: 7
Pages: 357-64
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19805092 | J:153697
First Author: Choi MK
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.
Volume: 106
Issue: 42
Pages: 17870-5
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Publication
31409781 | J:279390
First Author: Stone AEL
Year: 2019
Journal: Nat Commun
Title: RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection.
Volume: 10
Issue: 1
Pages: 3649
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Publication
32169840 | J:287487
First Author: Vongpipatana T
Year: 2020
Journal: J Immunol
Title: ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways.
Volume: 204
Issue: 8
Pages: 2156-2168
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Publication
26739051 | J:318622
First Author: Birdwell LD
Year: 2016
Journal: J Virol
Title: Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon.
Volume: 90
Issue: 6
Pages: 3160-72
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Publication
19995959 | J:155673
First Author: McCartney S
Year: 2009
Journal: J Exp Med
Title: Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells.
Volume: 206
Issue: 13
Pages: 2967-76
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Publication
24478444 | J:213001
First Author: Menachery VD
Year: 2014
Journal: J Virol
Title: Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.
Volume: 88
Issue: 8
Pages: 4251-64
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Publication
20360684 | J:159293
First Author: Chattopadhyay S
Year: 2010
Journal: EMBO J
Title: Viral apoptosis is induced by IRF-3-mediated activation of Bax.
Volume: 29
Issue: 10
Pages: 1762-73
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Publication
24270516 | J:209086
First Author: Chiang HS
Year: 2014
Journal: Nat Immunol
Title: GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses.
Volume: 15
Issue: 1
Pages: 63-71
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16116171 | J:113241
First Author: Yoneyama M
Year: 2005
Journal: J Immunol
Title: Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.
Volume: 175
Issue: 5
Pages: 2851-8
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Publication
31941663 | J:288804
First Author: Costa Cruz PH
Year: 2020
Journal: RNA
Title: A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing.
Volume: 26
Issue: 4
Pages: 454-469
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Publication
29492454 | J:260537
First Author: Linehan MM
Year: 2018
Journal: Sci Adv
Title: A minimal RNA ligand for potent RIG-I activation in living mice.
Volume: 4
Issue: 2
Pages: e1701854
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Publication
20592086 | J:307848
First Author: Zhou S
Year: 2010
Journal: J Virol
Title: Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
Volume: 84
Issue: 18
Pages: 9452-62
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Publication
20360967 | J:162953
First Author: DeWitte-Orr SJ
Year: 2010
Journal: PLoS Pathog
Title: An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses.
Volume: 6
Issue: 3
Pages: e1000829
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Publication
26939124 | J:245822
First Author: Pham AM
Year: 2016
Journal: PLoS Pathog
Title: PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.
Volume: 12
Issue: 3
Pages: e1005489
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