SRC kinase signalling inhibitor 1 (also known as SNAP-25-interacting protein, SNIP) acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signalling, leading to impaired cell spreading and migration [, ]. It regulates dendritic spine morphology []. It is involved in calcium-dependent exocytosis and may play a role in neurotransmitter release or synapse maintenance [, ].
