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Search results 501 to 555 out of 555 for Igf1r

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Publication

31267557 | J:285987

First Author:	Yang F
Year:	2019
Journal:	EMBO J
Title:	GSTZ1-1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone.
Volume:	38
Issue:	15
Pages:	e101964

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Publication

35647546 | J:327222

First Author:	Turvey SJ
Year:	2022
Journal:	RSC Med Chem
Title:	Recent developments in the structural characterisation of the IR and IGF1R: implications for the design of IR-IGF1R hybrid receptor modulators.
Volume:	13
Issue:	4
Pages:	360-374

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Publication

22373578 | J:182694

First Author:	Okamoto K
Year:	2012
Journal:	EMBO J
Title:	miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver.
Volume:	31
Issue:	7
Pages:	1752-63

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Publication

24636986 | J:209596

First Author:	Llobet-Navas D
Year:	2014
Journal:	Genes Dev
Title:	The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.
Volume:	28
Issue:	7
Pages:	765-82

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Publication

31991123 | J:293831

First Author:	Hu S
Year:	2020
Journal:	Brain Res
Title:	Knock down of lncRNA H19 promotes axon sprouting and functional recovery after cerebral ischemic stroke.
Volume:	1732

Pages:	146681

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Publication

26025657 | J:311070

First Author:	Simon CM
Year:	2015
Journal:	Acta Neuropathol
Title:	Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy.
Volume:	130
Issue:	3
Pages:	373-87

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Publication

35784559 | J:326453

First Author:	Bulatowicz JJ
Year:	2022
Journal:	Front Endocrinol (Lausanne)
Title:	Activation Versus Inhibition of IGF1R: A Dual Role in Breast Tumorigenesis.
Volume:	13

Pages:	911079

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Publication

36824269 | J:333759

First Author:	Yu Y
Year:	2023
Journal:	iScience
Title:	PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6.
Volume:	26
Issue:	2
Pages:	106070

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Publication

12138094 | -

First Author:	Pandini G
Year:	2002
Journal:	J Biol Chem
Title:	Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
Volume:	277
Issue:	42
Pages:	39684-95

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Publication

16831875 | -

First Author:	Slaaby R
Year:	2006
Journal:	J Biol Chem
Title:	Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.
Volume:	281
Issue:	36
Pages:	25869-74

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Publication

8276809 | -

First Author:	Van Horn DJ
Year:	1994
Journal:	J Biol Chem
Title:	Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.
Volume:	269
Issue:	1
Pages:	29-32

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Publication

10232609 | J:54539

First Author:	Kaplan PJ
Year:	1999
Journal:	Cancer Res
Title:	The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
Volume:	59
Issue:	9
Pages:	2203-9

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Publication

16027059 | J:102544

First Author:	Hishiya A
Year:	2005
Journal:	Bone
Title:	Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.
Volume:	37
Issue:	4
Pages:	497-503

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Publication

30419192 | J:269792

First Author:	Scully T
Year:	2019
Journal:	Exp Cell Res
Title:	Contrasting effects of IGF binding protein-3 expression in mammary tumor cells and the tumor microenvironment.
Volume:	374
Issue:	1
Pages:	38-45

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Publication

19500727 | J:151425

First Author:	Keisala T
Year:	2009
Journal:	J Steroid Biochem Mol Biol
Title:	Premature aging in vitamin D receptor mutant mice.
Volume:	115
Issue:	3-5
Pages:	91-7

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Publication

27927611 | J:239958

First Author:	Kawano F
Year:	2017
Journal:	Am J Physiol Cell Physiol
Title:	Prenatal myonuclei play a crucial role in skeletal muscle hypertrophy in rodents.
Volume:	312
Issue:	3
Pages:	C233-C243

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Publication

15194422 | J:92474

First Author:	Armand AS
Year:	2004
Journal:	Exp Cell Res
Title:	IGF-II is up-regulated and myofibres are hypertrophied in regenerating soleus of mice lacking FGF6.
Volume:	297
Issue:	1
Pages:	27-38

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Publication

25658474 | J:229048

First Author:	Sargent KM
Year:	2015
Journal:	PLoS One
Title:	Loss of vascular endothelial growth factor A (VEGFA) isoforms in granulosa cells using pDmrt-1-Cre or Amhr2-Cre reduces fertility by arresting follicular development and by reducing litter size in female mice.
Volume:	10
Issue:	2
Pages:	e0116332

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Publication

33577435 | J:305039

First Author:	Weeks KL
Year:	2021
Journal:	Am J Physiol Heart Circ Physiol
Title:	FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K.
Volume:	320
Issue:	4
Pages:	H1470-H1485

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Publication

27803039 | J:260786

First Author:	Zangi L
Year:	2017
Journal:	Circulation
Title:	Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury.
Volume:	135
Issue:	1
Pages:	59-72

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Publication

30981207 | J:290289

First Author:	Anisimov VN
Year:	2019
Journal:	Aging (Albany NY)
Title:	In mice transgenic for IGF1 under keratin-14 promoter, lifespan is decreased and the rates of aging and thymus involution are accelerated.
Volume:	11
Issue:	7
Pages:	2098-2110

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Publication

34527673 | J:310890

First Author:	Cao C
Year:	2021
Journal:	Front Cell Dev Biol
Title:	Lack of miR-379/miR-544 Cluster Resists High-Fat Diet-Induced Obesity and Prevents Hepatic Triglyceride Accumulation in Mice.
Volume:	9

Pages:	720900

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Publication

23454899 | J:200122

First Author:	Molina-Arcas M
Year:	2013
Journal:	Cancer Discov
Title:	Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer.
Volume:	3
Issue:	5
Pages:	548-63

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Publication

29099871 | J:252628

First Author:	Pope C
Year:	2017
Journal:	PLoS One
Title:	The role of H19, a long non-coding RNA, in mouse liver postnatal maturation.
Volume:	12
Issue:	11
Pages:	e0187557

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Publication

26324892 | J:226920

First Author:	Lovat F
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	miR-15b/16-2 deletion promotes B-cell malignancies.
Volume:	112
Issue:	37
Pages:	11636-41

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Publication

11777937 | J:73555

First Author:	Jiang Z
Year:	2002
Journal:	J Cell Biol
Title:	Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma.
Volume:	156
Issue:	1
Pages:	185-98

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Publication

9166590 | J:41150

First Author:	Jones CT
Year:	1997
Journal:	Mamm Genome
Title:	Gene homologs on human chromosome 15q21-q26 and a chicken microchromosome identify a new conserved segment.
Volume:	8
Issue:	6
Pages:	436-40

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Publication

20971705 | J:182914

First Author:	Beauvais DM
Year:	2010
Journal:	J Cell Sci
Title:	Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation.
Volume:	123
Issue:	Pt 21
Pages:	3796-807

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Publication

24801305 | J:222758

First Author:	Cuffe JS
Year:	2014
Journal:	J Physiol
Title:	Mid- to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex-specific manner.
Volume:	592
Issue:	14
Pages:	3127-41

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Publication

25609710 | J:223842

First Author:	Kang YJ
Year:	2015
Journal:	J Cell Sci
Title:	MiR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R.
Volume:	128
Issue:	4
Pages:	804-14

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Publication

26200114 | J:238617

First Author:	Gan J
Year:	2015
Journal:	PLoS One
Title:	Integrative Analysis of the Developing Postnatal Mouse Heart Transcriptome.
Volume:	10
Issue:	7
Pages:	e0133288

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Publication

28945762 | J:249834

First Author:	Solomon-Zemler R
Year:	2017
Journal:	PLoS One
Title:	Nuclear insulin-like growth factor-1 receptor (IGF1R) displays proliferative and regulatory activities in non-malignant cells.
Volume:	12
Issue:	9
Pages:	e0185164

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Publication

30509997 | J:268948

First Author:	Andersson KME
Year:	2018
Journal:	Proc Natl Acad Sci U S A
Title:	Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis.
Volume:	115
Issue:	51
Pages:	E12063-E12072

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Publication

34220714 | J:309898

First Author:	Achlaug L
Year:	2021
Journal:	Front Endocrinol (Lausanne)
Title:	ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease.
Volume:	12

Pages:	688104

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Publication

33749878 | J:339818

First Author:	Sekulovski N
Year:	2021
Journal:	FASEB J
Title:	Insulin signaling is an essential regulator of endometrial proliferation and implantation in mice.
Volume:	35
Issue:	4
Pages:	e21440

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Publication

27765041 | J:316548

First Author:	Farabaugh SM
Year:	2016
Journal:	Cell Commun Signal
Title:	Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer.
Volume:	14
Issue:	1
Pages:	25

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Publication

22625652 | J:318935

First Author:	Hu Q
Year:	2012
Journal:	ASN Neuro
Title:	Signalling through the type 1 insulin-like growth factor receptor (IGF1R) interacts with canonical Wnt signalling to promote neural proliferation in developing brain.
Volume:	4
Issue:	5

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Publication

23919516 | J:317850

First Author:	Watson KL
Year:	2013
Journal:	BMC Cancer
Title:	Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.
Volume:	13

Pages:	375

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Publication

23743496 | J:305867

First Author:	Katoh M
Year:	2013
Journal:	Exp Mol Med
Title:	Functional proteomics, human genetics and cancer biology of GIPC family members.
Volume:	45

Pages:	e26

•

Publication

31754018 | J:284199

First Author:	Wood CL
Year:	2020
Journal:	Dis Model Mech
Title:	A comparison of the bone and growth phenotype of mdx, mdx:Cmah^-/- and mdx:Utrn ^+/- murine models with the C57BL/10 wild-type mouse.
Volume:	13
Issue:	2

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Publication

22120709 | J:186116

First Author:	Church DN
Year:	2012
Journal:	Oncogene
Title:	Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse.
Volume:	31
Issue:	31
Pages:	3635-46

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Publication

31442251 | J:284312

First Author:	Gustafson JA
Year:	2019
Journal:	PLoS One
Title:	Calvarial osteoblast gene expression in patients with craniosynostosis leads to novel polygenic mouse model.
Volume:	14
Issue:	8
Pages:	e0221402

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Publication

32581853 | J:311465

First Author:	Yan W
Year:	2020
Journal:	Front Physiol
Title:	Deficiency of the Immunoproteasome LMP10 Subunit Attenuates Angiotensin II-Induced Cardiac Hypertrophic Remodeling via Autophagic Degradation of gp130 and IGF1R.
Volume:	11

Pages:	625

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Publication

23863936 | J:318976

First Author:	Venkatraman A
Year:	2013
Journal:	Nature
Title:	Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.
Volume:	500
Issue:	7462
Pages:	345-9

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Publication

37152930 | J:345990

First Author:	Zhang Q
Year:	2023
Journal:	Front Endocrinol (Lausanne)
Title:	Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia.
Volume:	14

Pages:	1030453

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Publication

36549436 | J:336795

First Author:	Wang Y
Year:	2023
Journal:	Metabolism
Title:	Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway.
Volume:	140

Pages:	155380

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Publication

25069779 | J:210803

First Author:	Hollern DP
Year:	2014
Journal:	Breast Cancer Res
Title:	A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer.
Volume:	16
Issue:	3
Pages:	R59

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Publication

19275641 | -

First Author:	Sharma PS
Year:	2009
Journal:	Curr Pharm Des
Title:	Receptor tyrosine kinase inhibitors as potent weapons in war against cancers.
Volume:	15
Issue:	7
Pages:	758-76

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Publication

16700535 | -

First Author:	Li E
Year:	2006
Journal:	Biochemistry
Title:	Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.
Volume:	45
Issue:	20
Pages:	6241-51

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Publication

15845350 | -

First Author:	Roskoski R Jr
Year:	2005
Journal:	Biochem Biophys Res Commun
Title:	Src kinase regulation by phosphorylation and dephosphorylation.
Volume:	331
Issue:	1
Pages:	1-14

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Publication

3291115 | J:31015

First Author:	Hanks SK
Year:	1988
Journal:	Science
Title:	The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Volume:	241
Issue:	4861
Pages:	42-52

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Publication

12368087 | -

First Author:	Manning G
Year:	2002
Journal:	Trends Biochem Sci
Title:	Evolution of protein kinase signaling from yeast to man.
Volume:	27
Issue:	10
Pages:	514-20

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Publication

12471243 | -

First Author:	Manning G
Year:	2002
Journal:	Science
Title:	The protein kinase complement of the human genome.
Volume:	298
Issue:	5600
Pages:	1912-34

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Publication

15078142 | -

First Author:	Stout TJ
Year:	2004
Journal:	Curr Pharm Des
Title:	High-throughput structural biology in drug discovery: protein kinases.
Volume:	10
Issue:	10
Pages:	1069-82

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Publication

15320712 | -

First Author:	Li B
Year:	2004
Journal:	Comb Chem High Throughput Screen
Title:	Creating chemical diversity to target protein kinases.
Volume:	7
Issue:	5
Pages:	453-72

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