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Search results 101 to 193 out of 193 for Brd3

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0.026s
Type Details Score
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:11815
Specimen Label: GUDMAP:11815
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6944
Specimen Label: GUDMAP:6944
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754021
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3507582
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Single cells
Stage: TS27
Assay Id: MGI:3507582
Age: postnatal newborn
Image: 2
Note: Expression was detected in some cells.
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6944
Specimen Label: GUDMAP:6944
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3507582
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3507582
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3507582
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6944
Specimen Label: GUDMAP:6944
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:11815
Specimen Label: GUDMAP:11815
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3507582
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Single cells
Stage: TS27
Assay Id: MGI:3507582
Age: postnatal newborn
Image: 2
Note: Expression was detected in some cells.
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6944
Specimen Label: GUDMAP:6944
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2875323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:11815
Note: Moderate expression in signaling center
Specimen Label: GUDMAP:11815
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3586327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5288718
Age: postnatal day 1
Specimen Label: Table 1 - P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5288718
Age: postnatal day 30
Specimen Label: Table 1 - P30
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5288718
Age: postnatal day 30
Image: 3A9
Specimen Label: 3A9
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5288718
Age: postnatal day 30
Image: 3A10
Specimen Label: 3A10
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5288718
Age: postnatal day 30
Image: 2B2
Specimen Label: 2B2
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5288718
Age: postnatal day 30
Image: S1C
Specimen Label: S1C
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2860123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:11815
Specimen Label: GUDMAP:11815
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539153
Age: embryonic day 15.5
Image: GUDMAP:5349
Specimen Label: GUDMAP:5349
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000704
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5541264
Age: embryonic day 15.5
Image: GUDMAP:6943
Specimen Label: GUDMAP:6943
Detected: false
Specimen Num: 1
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to RIKEN cDNA 2410084F24 gene, clone IMAGE:2650994, mRNA
Pages: BC004832
Protein
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: true
Publication
First Author: Bandukwala HS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors.
Volume: 109
Issue: 36
Pages: 14532-7
Publication
First Author: Zhang J
Year: 2013
Journal: J Biol Chem
Title: A newly identified microRNA, mmu-miR-7578, functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo.
Volume: 288
Issue: 6
Pages: 4310-20
Publication
First Author: Prokopuk L
Year: 2022
Journal: Reproduction
Title: An essential role for Polycomb Repressive Complex 2 in the mouse ovary.
Volume: 163
Issue: 3
Pages: 167-182
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Lamonica JM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes.
Volume: 108
Issue: 22
Pages: E159-68
Publication
First Author: Chen IP
Year: 2022
Journal: Cell Rep
Title: Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.
Volume: 40
Issue: 3
Pages: 111088
Protein Domain
Type: Family
Description: The gene encoding Nuclear Testis (NUT) protein is found fused to BRD3 or BRD4 genes in some aggressive types of carcinoma due to chromosomal translocations [, ]. Proteins of the BRD family contain two bromodomains that bind transcriptionally active chromatin through associations with acetylated histones H3 and H4 [, ]. Such proteins are crucial for the regulation of cell cycle progression. On the other hand, little is known about NUT protein function. NUT has a Nuclear Export Sequence (NES) as well as a Nuclear Localization Signal (NLS), both located towards the C-terminal end of the protein [, ]. A fused NUT-GFP protein has shown either cytoplasmic or nuclear localisation, suggesting that it is subject to nuclear/cytoplasmic shuttling. Consistent with this possibility, treatment with leptomycin B, an inhibitor of CRM1-dependent nuclear export, has been shown to result in re-distribution of NUT-GFP to the nucleus [, ].
Protein Domain
Type: Domain
Description: This domain is found in the N-terminal region of Nuclear Testis (NUT) proteins. The NUT gene is found fused to BRD3 or BRD4 genes in some aggressive types of carcinoma, due to chromosomal translocations [, ]. The BRD family proteins contain two bromodomains that bind transcriptionally active chromatin through associations with acetylated histones H3 and H4 [, ]. BRD proteins are crucial for the regulation of cell cycle progression. The function of NUT proteins is not clear. NUT proteins contain the Nuclear Export Sequence (NES) and the Nuclear Localisation Signal (NLS), both located towards the C-terminal end of the protein [, ]. NUT-GFP protein showed either cytoplasmic or nuclear localisation, suggesting that it is subject to nuclear/cytoplasmic shuttling. Consistent with this possibility, treatment with leptomycin B an inhibitor of CRM1-dependent nuclear export resulted in re-distribution of NUT-GFP to the nucleus [, ]. Inspection of NUT revealed a C-terminal sequence similar to known nuclear export NUT protein carries some natively unstructured sequence.
Protein
Organism: Mus musculus/domesticus
Length: 1126  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
Publication
First Author: Fornerod M
Year: 1997
Journal: Cell
Title: CRM1 is an export receptor for leucine-rich nuclear export signals.
Volume: 90
Issue: 6
Pages: 1051-60
Publication
First Author: French CA
Year: 2003
Journal: Cancer Res
Title: BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma.
Volume: 63
Issue: 2
Pages: 304-7
Publication
First Author: French CA
Year: 2008
Journal: Oncogene
Title: BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.
Volume: 27
Issue: 15
Pages: 2237-42
Publication
First Author: Ossareh-Nazari B
Year: 1997
Journal: Science
Title: Evidence for a role of CRM1 in signal-mediated nuclear protein export.
Volume: 278
Issue: 5335
Pages: 141-4
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7