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Search results 101 to 121 out of 121 for Rbm6

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0.017s
Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif 1 (RRM1) of RBM6 (also known as lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3), which has been predicted to be a nuclear factor based on its nuclear localization signal [, , ]. RBM6 shows high sequence similarity to RNA-binding protein 5 (RBM5). Both RBM6 and RBM5 specifically bind poly(G) RNA. They contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has two additional unique domains: the decamer repeat occurring more than 20 times, and the POZ (poxvirus and zinc finger) domain. The POZ domain may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers [, , ].
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of RBM6 (also known as lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3), which has been predicted to be a nuclear factor based on its nuclear localization signal [, , ]. RBM6 shows high sequence similarity to RNA-binding protein 5 (RBM5). Both RBM6 and RBM5 specifically bind poly(G) RNA. They contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has two additional unique domains: the decamer repeat occurring more than 20 times, and the POZ (poxvirus and zinc finger) domain. The POZ domain may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers [, , ].
Publication
First Author: Güre AO
Year: 1998
Journal: Cancer Res
Title: Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3.
Volume: 58
Issue: 5
Pages: 1034-41
Publication
First Author: Sutherland LC
Year: 2005
Journal: J Cell Biochem
Title: RNA binding motif (RBM) proteins: a novel family of apoptosis modulators?
Volume: 94
Issue: 1
Pages: 5-24
Protein Domain
Type: Domain
Description: RNA-binding protein 6 (RBM6) contains two RNA-binding motifs and shares protein sequence similarity with RBM5 []. RBM6 is targeted to the splicing speckles and nascent transcripts []. It may act mainly as a splicing activator []. The elevated expression of RBM6 has been linked to certain tumours []. A RBM6-CSF1R fusion has been found in acute megakaryoblastic leukemia [].RBM6 contains two RNA recognition motifs (RRMs), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has an additional unique domain, the POZ (poxvirus andzinc finger) domain, which may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers. This entry represents the OCRE domain.The OCRE (OCtamer REpeat) domain contains five repeats of an 8-residue motif, which were shown to form β-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed [].
Publication
First Author: Mackereth CD
Year: 2012
Journal: Curr Opin Struct Biol
Title: Dynamics in multi-domain protein recognition of RNA.
Volume: 22
Issue: 3
Pages: 287-96
Publication
First Author: Muto Y
Year: 2012
Journal: Wiley Interdiscip Rev RNA
Title: Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems.
Volume: 3
Issue: 2
Pages: 229-46
Publication  
First Author: McDaid AF
Year: 2017
Journal: Nat Commun
Title: Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
Volume: 8
Pages: 15842
Publication
First Author: Callebaut I
Year: 2005
Journal: Bioinformatics
Title: OCRE: a novel domain made of imperfect, aromatic-rich octamer repeats.
Volume: 21
Issue: 6
Pages: 699-702