|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 180 out of 180 for Shroom1

<< First    < Previous  |  Next >    Last >>
0.023s
Type Details Score
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1624622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Note: Expression was weak in the digestive system.
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1721422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Scattered
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Scattered
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Scattered
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Scattered
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Image: MH457; Specimen C1184
Specimen Label: MH457; Specimen C1184
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724383
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5421043
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH457; Specimen C1184
Detected: false
Specimen Num: 1
Publication
First Author: Mohan S
Year: 2012
Journal: Mol Biol Cell
Title: Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction.
Volume: 23
Issue: 11
Pages: 2131-42
Protein
Organism: Mus musculus/domesticus
Length: 823  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 715  
Fragment?: false
Publication
First Author: Etournay R
Year: 2007
Journal: J Cell Sci
Title: Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.
Volume: 120
Issue: Pt 16
Pages: 2838-50
Publication  
First Author: Ahuja N
Year: 2022
Journal: Dev Biol
Title: Endothelial Cyp26b1 restrains murine heart valve growth during development.
Volume: 486
Pages: 81-95
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Protein
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
Protein Domain
Type: Family
Description: The Shroom family is a small group of related proteins that are defined by sequence similarity and in most cases by some link to the actin cytoskeleton. The Shroom (Shrm) protein family is found only in animals. Proteins of this family are predicted to be utilised in multiple morphogenic and developmental processes across animal phyla to regulate cells shape or intracellular architecture in an actin and myosin-dependent manner []. The Shrm family consists of:Shrm1 (formerly Apx), first found in Xenopus []. Human Shroom1 links a membrane bound protein to the actin cytoskeleton [].Shrm2 (formerly Apxl), a protein involved in the morphogenesis, maintenance, and/or function of vascular endothelial cells. Shrm3 (formerly Shroom), a protein necessary for neural tube closure in vertebrate development as deficiency in Shrm results in spina bifida. Shrm3 is also conserved in some invertebrates, as orthologues can be found in sea urchins. Shrm4, a regulator of cyto-skeletal architecture that may play an important role in vertebrate development. It is implicated in X-linked mental retardation in humans.
Protein
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
Protein Domain
Type: Domain
Description: This entry represents the ASD2 motif of the Shroom proteins. The Shroom family is a small group of related proteins that are defined by sequence similarity and in most cases by some link to the actin cytoskeleton. The Shroom (Shrm) protein family is found only in animals. Proteins of this family are predicted to be utilised in multiple morphogenic and developmental processes across animal phyla to regulate cells shape or intracellular architecture in an actin and myosin-dependent manner []. The Shrm family consists of:Shrm1 (formerly Apx), first found in Xenopus []. Human Shroom1 links a membrane bound protein to the actin cytoskeleton [].Shrm2 (formerly Apxl), a protein involved in the morphogenesis, maintenance, and/or function of vascular endothelial cells. Shrm3 (formerly Shroom), a protein necessary for neural tube closure in vertebrate development as deficiency in Shrm results in spina bifida. Shrm3 is also conserved in some invertebrates, as orthologues can be found in sea urchins. Shrm4, a regulator of cyto-skeletal architecture that may play an important role in vertebrate development. It is implicated in X-linked mental retardation in humans. This protein family is based on the conservation of a specific arrangement of an N-terminal PDZ domain, a centrally positioned sequence motif termed ASD1 (Apx/Shrm Domain 1) and a C-terminal motif termed ASD2 [, , ]. Shrm2 and Shrm3 contain all three domains, while Shrm4 contains the PDZ and ASD2 domains, but lacks a discernible ASD1 element. To date, the ASD1 and ASD2 elements have only been found in Shrm-related proteins and do not appear in combination with other conserved domains. ASD1 is required for targeting actin, while ASD2 is capable of eliciting an actomyosin based constriction event [, ]. ASD2 is the most highly conserved sequence element shared by Shrm1, Shrm2, Shrm3, and Shrm4. It possesses a well conserved series of leucine residues that exhibit spacing consistent with that of a leucine zipper motif [].
Protein Domain
Type: Domain
Description: This entry represents the ASD1 (Apx/Shrm Domain 1) motif of the Shroom proteins. The Shroom family is a small group of related proteins that are defined by sequence similarity and in most cases by some link to the actin cytoskeleton. The Shroom (Shrm) protein family is found only in animals. Proteins of this family are predicted to be utilised in multiple morphogenic and developmental processes across animal phyla to regulate cells shape or intracellular architecture in an actin and myosin-dependent manner []. The Shrm family consists of:Shrm1 (formerly Apx), first found in Xenopus []. Human Shroom1 links a membrane bound protein to the actin cytoskeleton [].Shrm2 (formerly Apxl), a protein involved in the morphogenesis, maintenance, and/or function of vascular endothelial cells. Shrm3 (formerly Shroom), a protein necessary for neural tube closure in vertebrate development as deficiency in Shrm results in spina bifida. Shrm3 is also conserved in some invertebrates, as orthologues can be found in sea urchins. Shrm4, a regulator of cyto-skeletal architecture that may play an important role in vertebrate development. It is implicated in X-linked mental retardation in humans. This protein family is based on the conservation of a specific arrangement of an N-terminal PDZ domain, a centrally positioned sequence motif termed ASD1 (Apx/Shrm Domain 1) and a C-terminal motif termed ASD2 [, , ]. Shrm2 and Shrm3 contain all three domains, while Shrm4 contains the PDZ and ASD2 domains, but lacks a discernible ASD1 element. To date, the ASD1 and ASD2 elements have only been found in Shrm-related proteins and do not appear in combination with other conserved domains. ASD1 is required for targeting actin, while ASD2 is capable of eliciting an actomyosin based constriction event [, ]. ASD2 is the most highly conserved sequence element shared by Shrm1, Shrm2, Shrm3, and Shrm4. It possesses a well conserved series of leucine residues that exhibit spacing consistent with that of a leucine zipper motif [].
Publication
First Author: Yoder M
Year: 2007
Journal: Cell Motil Cytoskeleton
Title: Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization.
Volume: 64
Issue: 1
Pages: 49-63
Protein
Organism: Mus musculus/domesticus
Length: 1805  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1899  
Fragment?: false
Publication
First Author: Dye DE
Year: 2009
Journal: Cell Mol Life Sci
Title: hShroom1 links a membrane bound protein to the actin cytoskeleton.
Volume: 66
Issue: 4
Pages: 681-96
Protein
Organism: Mus musculus/domesticus
Length: 1481  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1986  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1980  
Fragment?: false
Publication
First Author: Hildebrand JD
Year: 1999
Journal: Cell
Title: Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice.
Volume: 99
Issue: 5
Pages: 485-97
Protein
Organism: Mus musculus/domesticus
Length: 1475  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1849  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1849  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
Publication
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112