Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3690856 |
Assay Type: |
RT-PCR |
Annotation Date: |
2006-12-18 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3691188 |
Age: |
postnatal week 2 |
|
|
Specimen Label: |
Ovary |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1706828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692441 |
Age: |
postnatal adult |
Image: |
JAX_1305960 |
|
Specimen Label: |
JAX_1305960 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3690859 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-12-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:3690904 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
4H |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_13 |
|
Specimen Label: |
euxassay_002482_13 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_14 |
|
Specimen Label: |
euxassay_002482_14 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_15 |
|
Specimen Label: |
euxassay_002482_15 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_16 |
|
Specimen Label: |
euxassay_002482_16 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_17 |
|
Specimen Label: |
euxassay_002482_17 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824828 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002482_18 |
|
Specimen Label: |
euxassay_002482_18 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3690859 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-12-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684620 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:3690904 |
Age: |
embryonic day 12.0 |
|
Note: |
Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes. |
Specimen Label: |
4B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3690859 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-12-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
Pattern: |
Non-Uniform |
Stage: |
TS21 |
Assay Id: |
MGI:3690904 |
Age: |
embryonic day 13.0 |
|
Note: |
Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes. |
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3690859 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-12-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684623 |
Pattern: |
Non-Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:3690904 |
Age: |
embryonic day 15.0 |
|
Note: |
Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes. |
Specimen Label: |
4F |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3690865 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2006-12-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:3690912 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in the liver with particularly high signals in megakaryocytes. |
Specimen Label: |
5E, 5E' |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692441 |
Age: |
postnatal adult |
Image: |
JAX_1305961 |
|
Specimen Label: |
JAX_1305961 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7576142 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7576142 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1803007 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3518622 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7576142 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692441 |
Age: |
postnatal adult |
Image: |
JAX_1305959 |
|
Specimen Label: |
JAX_1305959 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
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Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Allele |
Name: |
fermitin family member 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Allele |
Name: |
fermitin family member 3; targeted mutation 1, Reinhard Fassler |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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•
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Allele |
Name: |
RAS, guanyl releasing protein 2; targeted mutation 1, Ann M Graybiel |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Genotype |
Symbol: |
Rasgrp2/Rasgrp2 |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
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•
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Genotype |
Symbol: |
Fermt3/Fermt3 |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
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DO Term |
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•
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Allele |
Name: |
fermitin family member 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
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Allele |
Name: |
integrin beta 2; targeted mutation 1.1, TaconicArtemis |
Allele Type: |
Targeted |
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Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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Publication |
First Author: |
Meakin PJ |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation. |
Volume: |
10 |
Issue: |
9 |
Pages: |
e0138872 |
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•
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Publication |
First Author: |
Savinko TS |
Year: |
2015 |
Journal: |
J Invest Dermatol |
Title: |
Functional Beta2-Integrins Restrict Skin Inflammation In Vivo. |
Volume: |
135 |
Issue: |
9 |
Pages: |
2249-2257 |
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Genotype |
Symbol: |
Itgb2/Itgb2 |
Background: |
involves: C57BL/6NTac |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
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Publication |
First Author: |
Weinstein EJ |
Year: |
2003 |
Journal: |
Biochim Biophys Acta |
Title: |
URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas. |
Volume: |
1637 |
Issue: |
3 |
Pages: |
207-16 |
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Publication |
First Author: |
Liu J |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. |
Volume: |
286 |
Issue: |
50 |
Pages: |
43334-42 |
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•
•
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Publication |
First Author: |
Rozario T |
Year: |
2014 |
Journal: |
Mech Dev |
Title: |
Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis. |
Volume: |
133 |
|
Pages: |
203-17 |
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•
•
•
•
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Publication |
First Author: |
Canning CA |
Year: |
2011 |
Journal: |
Dev Dyn |
Title: |
Developmental expression of the fermitin/kindlin gene family in Xenopus laevis embryos. |
Volume: |
240 |
Issue: |
8 |
Pages: |
1958-63 |
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•
•
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•
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Publication |
First Author: |
Ye F |
Year: |
2014 |
Journal: |
Front Med |
Title: |
Talin and kindlin: the one-two punch in integrin activation. |
Volume: |
8 |
Issue: |
1 |
Pages: |
6-16 |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
266
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
93
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
72
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
258
|
Fragment?: |
true |
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•
•
•
•
|