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Search results 101 to 200 out of 222 for Upf2

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Type Details Score
HT Experiment
E-MTAB-7064 | Microarray profiling of UPF2-deficient mouse GV oocytes
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Sample
UPF2 cKO 1
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal adult
Stage: 28
Structure . Name: primary spermatocyte
Notes: pachytene/diplotene stage
Curation Status: Curated
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HT Sample
UPF2 cKO 2
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal adult
Stage: 28
Structure . Name: primary spermatocyte
Notes: pachytene/diplotene stage
Curation Status: Curated
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HT Sample
UPF2 cKO 3
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal adult
Stage: 28
Structure . Name: primary spermatocyte
Notes: pachytene/diplotene stage
Curation Status: Curated
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HT Sample
UPF2 cKO 1
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 3-5
Stage: 28
Structure . Name: primary oocyte
Notes: germinal vesicle stage
Curation Status: Curated
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HT Sample
UPF2 cKO 2
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 3-5
Stage: 28
Structure . Name: primary oocyte
Notes: germinal vesicle stage
Curation Status: Curated
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HT Sample
UPF2 cKO 3
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 3-5
Stage: 28
Structure . Name: primary oocyte
Notes: germinal vesicle stage
Curation Status: Curated
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HT Experiment
E-MEXP-2248 | Transcription profiling of fetal livers of UPF2 null mice
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
A2AT37
Organism: Mus musculus/domesticus
Length: 1269  
Fragment?: false
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HT Experiment
GSE191039 | RNA sequencing of blastocyst-stage mouse embryos in the presence or absence of RNA decay activator UPF2
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
15004547 | -
First Author: Kadlec J
Year: 2004
Journal: Nat Struct Mol Biol
Title: The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3.
Volume: 11
Issue: 4
Pages: 330-7
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Publication
18066079 | -
First Author: Chamieh H
Year: 2008
Journal: Nat Struct Mol Biol
Title: NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
Volume: 15
Issue: 1
Pages: 85-93
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Allele
Upf2<+> | MGI:2449308
   
Name: UPF2 regulator of nonsense transcripts homolog (yeast); wild type
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Publication
11113196 | -
First Author: Serin G
Year: 2001
Journal: Mol Cell Biol
Title: Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4).
Volume: 21
Issue: 1
Pages: 209-23
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Allele
Upf2<Gt(OST23276)Lex> | MGI:4145807
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST23276, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<tm1e(EUCOMM)Hmgu> | MGI:4458668
Name: UPF2 regulator of nonsense transcripts homolog (yeast); targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Upf2<Gt(OST112106)Lex> | MGI:4188358
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST112106, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST123052)Lex> | MGI:4193712
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST123052, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST216958)Lex> | MGI:4236804
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST216958, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(XF042)Byg> | MGI:4127997
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap XF042, BayGenomics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST117307)Lex> | MGI:4190766
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST117307, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST100587)Lex> | MGI:4183449
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST100587, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST56720)Lex> | MGI:4165004
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST56720, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(EUCE0089d11)Hmgu> | MGI:4385247
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap EUCE0089d11, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST116634)Lex> | MGI:4190511
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST116634, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST308453)Lex> | MGI:4274053
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST308453, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST458991)Lex> | MGI:4324564
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST458991, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST1729)Lex> | MGI:4132107
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST1729, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<tm1Btp> | MGI:3790198
Name: UPF2 regulator of nonsense transcripts homolog (yeast); targeted mutation 1, Bo Torben Porse
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Upf2<Gt(OST219025)Lex> | MGI:4237788
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST219025, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(EUCJ0022h09)Hmgu> | MGI:4869633
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap EUCJ0022h09, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST169414)Lex> | MGI:4212976
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST169414, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(A20000)Wrst> | MGI:4335443
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap A20000, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<em2Cya> | MGI:7587429
Name: UPF2 regulator of nonsense transcripts homolog (yeast); endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Upf2<Gt(P062E01)Wrst> | MGI:3865703
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap P062E01, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(CSE040)Byg> | MGI:3875852
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap CSE040, BayGenomics
Allele Type: Gene trapped
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Allele
Upf2<Gt(D129D01)Wrst> | MGI:3891524
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap D129D01, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST279983)Lex> | MGI:4262072
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST279983, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<tm1a(EUCOMM)Hmgu> | MGI:4457521
Name: UPF2 regulator of nonsense transcripts homolog (yeast); targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Upf2<Gt(E077D10)Wrst> | MGI:3895257
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap E077D10, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST206279)Lex> | MGI:4231762
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST206279, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(E129D01)Wrst> | MGI:3896505
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap E129D01, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST303558)Lex> | MGI:4272552
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST303558, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(EUCJ0144c09)Hmgu> | MGI:4875126
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap EUCJ0144c09, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Upf2<Gt(CSE032)Byg> | MGI:3875857
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap CSE032, BayGenomics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST291658)Lex> | MGI:4267505
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST291658, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST374191)Lex> | MGI:4298359
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST374191, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(E085B04)Wrst> | MGI:3895507
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap E085B04, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST55804)Lex> | MGI:4164385
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST55804, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST199282)Lex> | MGI:4228225
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST199282, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST396993)Lex> | MGI:4305111
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST396993, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST275663)Lex> | MGI:4260054
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST275663, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(E144B02)Wrst> | MGI:3915695
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap E144B02, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST67267)Lex> | MGI:4171750
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST67267, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST208792)Lex> | MGI:4233013
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST208792, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(M123A12)Wrst> | MGI:3859675
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap M123A12, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(P068C10)Wrst> | MGI:3866066
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap P068C10, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST67670)Lex> | MGI:4172037
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST67670, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST276960)Lex> | MGI:4260675
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST276960, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST220857)Lex> | MGI:4238755
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST220857, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST230828)Lex> | MGI:4242357
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST230828, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST111408)Lex> | MGI:4188028
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST111408, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(OST201236)Lex> | MGI:4229299
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST201236, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<tm1.1Btp> | MGI:3790199
Name: UPF2 regulator of nonsense transcripts homolog (yeast); targeted mutation 1.1, Bo Torben Porse
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Upf2<Gt(OST279012)Lex> | MGI:4261576
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap OST279012, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Upf2<Gt(IST14664F12)Tigm> | MGI:5249613
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST14664F12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Upf2<Gt(IST14592H5)Tigm> | MGI:5244562
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST14592H5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Upf2<Gt(271A6)Cmhd> | MGI:4960348
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap 271A6, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Upf2<Gt(IST14740B11)Tigm> | MGI:5258094
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST14740B11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Upf2<Gt(IST13373A7)Tigm> | MGI:5163999
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST13373A7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:7589620 | C57BL/6J-Upf2<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Upf2<Gt(IST13930C8)Tigm> | MGI:5193995
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST13930C8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Upf2<Gt(IST14707B5)Tigm> | MGI:5256770
 
Name: UPF2 regulator of nonsense transcripts homolog (yeast); gene trap IST14707B5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Upf2/Upf2
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Lyz2/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Lck-cre)548Jxm/? Upf2/Upf2
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Atoh1-cre)1Bfri/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Alb1-cre)7Gsc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Stra8-icre)1Reb/?
Background: involves: 129P2/OlaHsd * C57BL/6N * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Zp3-cre)93Knw/?
Background: involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR039762 | Nmd2/UPF2
Type: Family
Description: This entry includes Nmd2 from yeasts and UPF2 from animals. They are involved in the nonsense-mediated mRNA decay (NMD) pathway [, ]. In the human UPF complex (composed of UPF1/2/3), UPF2 and UPF3b cooperatively stimulate both ATPase and RNA helicase activities of UPF1 [].
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Publication
21419344 | -
First Author: Chakrabarti S
Year: 2011
Journal: Mol Cell
Title: Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2.
Volume: 41
Issue: 6
Pages: 693-703
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Publication
19556969 | -
First Author: Clerici M
Year: 2009
Journal: EMBO J
Title: Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2.
Volume: 28
Issue: 15
Pages: 2293-306
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Protein Domain
IPR040812 | UPF1_1B_dom
Type: Domain
Description: UPF1 (or regulator of nonsense transcripts 1 homologue) is an essential RNA helicase that detects mRNAs containing premature stop codons and triggers their degradation. Together with UPF2 and UPF3, forms a surveillance complex, in which UPF2 acts as a bridge between UPF1 and UPF3. UPF2 and UPF3 are nonenzymatic components of the complex that stimulate the activity of UPF1 []. UPF1 has a N-terminal cysteine/histidine-rich zinc-binding domain (CH/ZBD), a regulatory 1B domain, followed by a helicase core that belongs to superfamily 1 (SF1).This is 1B domain of UPF1 which has a regulatory role. It suffers conformational changes from an inhibitory state to a transition-state complex that modulate RNA binding [, ].
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Genotype
Genotype
Symbol: Upf2/Upf2 En1/En1<+>
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
16931876 | -
First Author: Kadlec J
Year: 2006
Journal: RNA
Title: Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1.
Volume: 12
Issue: 10
Pages: 1817-24
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Protein Domain
IPR018999 | UPF1_CH/ZBD
Type: Domain
Description: UPF1 (or regulator of nonsense transcripts 1 homologue) is an essential RNA helicase that detects mRNAs containing premature stop codons and triggers their degradation. Together with UPF2 and UPF3, forms a surveillance complex, in which UPF2 acts as a bridge between UPF1 and UPF3. UPF2 and UPF3 are nonenzymatic components of the complex that stimulate the activity of UPF1 []. UPF1 has a N-terminal cysteine/histidine-rich zinc-binding domain (CH/ZBD), a regulatory 1B domain, followed by a helicase core that belongs to superfamily 1 (SF1).This is the N-terminal CH/ZBD which contains 3 zinc binding motifs that interacts with UPF2 and it also has a cis-inhibitory effect on the ATPase activity. After binding to UPF2, the CH/ZBD suffers a large conformational change that causes the catalytic helicase domain to bind RNA less extensively and triggering its helicase activity [, ].
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Protein
F6Q8N5
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Publication
11368911 | -
First Author: Aronoff R
Year: 2001
Journal: Gene
Title: Molecular identification of smg-4, required for mRNA surveillance in C. elegans.
Volume: 268
Issue: 1-2
Pages: 153-64
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Publication
12718880 | -
First Author: Gehring NH
Year: 2003
Journal: Mol Cell
Title: Y14 and hUpf3b form an NMD-activating complex.
Volume: 11
Issue: 4
Pages: 939-49
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Publication
15048104 | -
First Author: Lykke-Andersen J
Year: 2004
Journal: Nat Struct Mol Biol
Title: Making structural sense of nonsense-mediated decay.
Volume: 11
Issue: 4
Pages: 305-6
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Protein Domain
IPR005120 | UPF3_dom
Type: Domain
Description: Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism by which eukaryotic cells detect and degrade transcripts containing premature termination codons. Three 'up-frameshift' proteins, UPF1, UPF2 and UPF3, are essential for this process in organisms ranging from yeast, human to plants []. Exon junction complexes (EJCs) are deposited ~24 nucleotides upstream of exon-exon junctions after splicing. Translation causes displacement of the EJCs, however, premature translation termination upstream of one or more EJCs triggers the recruitment of UPF1, UPF2 and UPF3 and activates the NMD pathway [, ]. This entry contains UPF3. The crystal structure of the complex between human UPF2 and UPF3b, which are, respectively, a MIF4G (middle portion of eIF4G) domain and an RNP domain (ribonucleoprotein-type RNA-binding domain) has been determined to 1.95A. The protein-protein interface is mediated by highly conserved charged residues in UPF2 and UPF3b and involves the β-sheet surface of the UPF3b ribonucleoprotein (RNP) domain, which is generally used by these domains to bind nucleic acids. In UPF3b the RNP domain does not bind RNA, whereas the UPF2 construct and the complex do. It is clear that some RNP domains have evolved for specific protein-protein interactions rather than as nucleic acid binding modules [].
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Genotype
Genotype
Symbol: Upf2/Upf2 Tg(Stra8-icre)1Reb/?
Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Upf2/Upf2 Plekha5/Plekha5<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
9032286 | -
First Author: He F
Year: 1997
Journal: Mol Cell Biol
Title: Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway.
Volume: 17
Issue: 3
Pages: 1580-94
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Publication
11532962 | J:320148
First Author: Le Hir H
Year: 2001
Journal: EMBO J
Title: The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
Volume: 20
Issue: 17
Pages: 4987-97
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