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Search results 1 to 100 out of 328 for Atr

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Category: Publication
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Type Details Score
Publication
10691732 | J:60768
First Author: Brown EJ
Year: 2000
Journal: Genes Dev
Title: ATR disruption leads to chromosomal fragmentation and early embryonic lethality.
Volume: 14
Issue: 4
Pages: 397-402
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Publication
12629044 | J:83042
First Author: Brown EJ
Year: 2003
Journal: Genes Dev
Title: Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance.
Volume: 17
Issue: 5
Pages: 615-28
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Publication
10801416 | J:61732
First Author: de Klein A
Year: 2000
Journal: Curr Biol
Title: Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Volume: 10
Issue: 8
Pages: 479-82
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Publication
8843195 | J:35913
First Author: Keegan KS
Year: 1996
Journal: Genes Dev
Title: The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.
Volume: 10
Issue: 19
Pages: 2423-37
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Publication
11721054 | J:314777
First Author: Cortez D
Year: 2001
Journal: Science
Title: ATR and ATRIP: partners in checkpoint signaling.
Volume: 294
Issue: 5547
Pages: 1713-6
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Publication
19782648 | J:153964
First Author: O'Driscoll M
Year: 2009
Journal: DNA Repair (Amst)
Title: Mouse models for ATR deficiency.
Volume: 8
Issue: 11
Pages: 1333-7
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Publication
20801936 | J:164024
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
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Publication
23039116 | J:192634
First Author: Kogo H
Year: 2012
Journal: Genes Cells
Title: HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.
Volume: 17
Issue: 11
Pages: 897-912
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Publication
30559436 | J:269157
First Author: Menolfi D
Year: 2018
Journal: Nat Commun
Title: Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.
Volume: 9
Issue: 1
Pages: 5351
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Publication
34210973 | J:326999
First Author: Kirtay M
Year: 2021
Journal: Nat Commun
Title: ATR regulates neuronal activity by modulating presynaptic firing.
Volume: 12
Issue: 1
Pages: 4067
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Publication
29977027 | J:267878
First Author: Pacheco S
Year: 2018
Journal: Nat Commun
Title: ATR is required to complete meiotic recombination in mice.
Volume: 9
Issue: 1
Pages: 2622
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Publication
31489491 | J:307570
First Author: Pacheco S
Year: 2019
Journal: Chromosoma
Title: ATR function is indispensable to allow proper mammalian follicle development.
Volume: 128
Issue: 3
Pages: 489-500
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Publication
23824539 | J:199454
First Author: Royo H
Year: 2013
Journal: Genes Dev
Title: ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing.
Volume: 27
Issue: 13
Pages: 1484-94
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Publication
22266795 | J:181920
First Author: Lee Y
Year: 2012
Journal: EMBO J
Title: ATR maintains select progenitors during nervous system development.
Volume: 31
Issue: 5
Pages: 1177-89
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Publication
10382071 | J:55411
First Author: Moens PB
Year: 1999
Journal: Chromosoma
Title: The association of ATR protein with mouse meiotic chromosome cores.
Volume: 108
Issue: 2
Pages: 95-102
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Publication
22078264 | J:316805
First Author: Zhou Z
Year: 2012
Journal: DNA Repair (Amst)
Title: Differential function of NBS1 and ATR in neurogenesis.
Volume: 11
Issue: 2
Pages: 210-21
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Publication
29976923 | J:266323
First Author: Widger A
Year: 2018
Journal: Nat Commun
Title: ATR is a multifunctional regulator of male mouse meiosis.
Volume: 9
Issue: 1
Pages: 2621
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Publication
28123024 | J:239152
First Author: Enriquez-Rios V
Year: 2017
Journal: J Neurosci
Title: DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Volume: 37
Issue: 4
Pages: 893-905
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Publication
24675793 | J:214145
First Author: Brown AD
Year: 2014
Journal: PLoS One
Title: ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair.
Volume: 9
Issue: 3
Pages: e91222
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Publication
19504344 | J:150723
First Author: Ragland RL
Year: 2009
Journal: Mamm Genome
Title: Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response.
Volume: 20
Issue: 6
Pages: 375-85
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Publication
26209650 | J:239795
First Author: Fedoriw AM
Year: 2015
Journal: Development
Title: Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.
Volume: 142
Issue: 17
Pages: 2972-80
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Publication
25838540 | J:221585
First Author: Lopez-Contreras AJ
Year: 2015
Journal: Genes Dev
Title: Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.
Volume: 29
Issue: 7
Pages: 690-5
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Publication
21826105 | J:184053
First Author: Yu Z
Year: 2012
Journal: Cell Res
Title: The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Volume: 22
Issue: 2
Pages: 305-20
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Publication
32973141 | J:300215
First Author: Kidiyoor GR
Year: 2020
Journal: Nat Commun
Title: ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration.
Volume: 11
Issue: 1
Pages: 4828
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Publication
18245444 | J:131573
First Author: Toledo LI
Year: 2008
Journal: Genes Dev
Title: ATR signaling can drive cells into senescence in the absence of DNA breaks.
Volume: 22
Issue: 3
Pages: 297-302
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Publication
20818375 | J:164430
First Author: Liu H
Year: 2010
Journal: Nature
Title: Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Volume: 467
Issue: 7313
Pages: 343-6
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Publication
20212315 | J:157978
First Author: McNees CJ
Year: 2010
Journal: J Cell Biol
Title: ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Volume: 188
Issue: 5
Pages: 639-52
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Publication
28273450 | J:251063
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
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Publication
14718568 | J:90049
First Author: Perera D
Year: 2004
Journal: Mol Biol Cell
Title: TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.
Volume: 15
Issue: 4
Pages: 1568-79
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Publication
23297361 | J:280203
First Author: Valdés-Sánchez L
Year: 2013
Journal: Hum Mol Genet
Title: ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.
Volume: 22
Issue: 8
Pages: 1507-15
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Publication
16213462 | J:102731
First Author: Ouyang Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.
Volume: 337
Issue: 3
Pages: 875-80
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Publication
27067599 | J:249000
First Author: Ruiz S
Year: 2016
Journal: Mol Cell
Title: A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Volume: 62
Issue: 2
Pages: 307-13
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Publication
19718024 | J:155013
First Author: Ruzankina Y
Year: 2009
Journal: Nat Genet
Title: Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Volume: 41
Issue: 10
Pages: 1144-9
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Publication
15282542 | J:92291
First Author: Fang Y
Year: 2004
Journal: EMBO J
Title: ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
Volume: 23
Issue: 15
Pages: 3164-74
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Publication
29279380 | J:258375
First Author: Cheng A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.
Volume: 115
Issue: 2
Pages: E292-E301
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Publication
31589169 | J:280953
First Author: Kishi S
Year: 2019
Journal: J Clin Invest
Title: Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses.
Volume: 129
Issue: 11
Pages: 4797-4816
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Publication
18691676 | J:142971
First Author: Kedar PS
Year: 2008
Journal: DNA Repair (Amst)
Title: Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.
Volume: 7
Issue: 11
Pages: 1787-98
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18160412 | J:172160
First Author: Entezam A
Year: 2008
Journal: Nucleic Acids Res
Title: ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.
Volume: 36
Issue: 3
Pages: 1050-6
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18371340 | J:123200
First Author: Ruzankina Y
Year: 2007
Journal: Cell Stem Cell
Title: Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.
Volume: 1
Issue: 1
Pages: 113-26
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Publication
17687332 | J:125120
First Author: Denchi EL
Year: 2007
Journal: Nature
Title: Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Volume: 448
Issue: 7157
Pages: 1068-71
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Publication
18606783 | J:139870
First Author: Hitomi M
Year: 2008
Journal: Mol Cell Biol
Title: Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression.
Volume: 28
Issue: 17
Pages: 5478-93
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Publication
27803059 | J:237522
First Author: Lang PY
Year: 2016
Journal: Development
Title: ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
Volume: 143
Issue: 21
Pages: 4038-4052
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Publication
21098704 | J:166996
First Author: Gilad O
Year: 2010
Journal: Cancer Res
Title: Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.
Volume: 70
Issue: 23
Pages: 9693-702
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Publication
18344416 | J:136629
First Author: Kulkarni A
Year: 2008
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.
Volume: 294
Issue: 5
Pages: L998-L1006
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Publication
19710035 | J:173019
First Author: Entezam A
Year: 2009
Journal: Nucleic Acids Res
Title: ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice.
Volume: 37
Issue: 19
Pages: 6371-7
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Publication
33110058 | J:299031
First Author: Matos-Rodrigues GE
Year: 2020
Journal: Cell Death Dis
Title: ATRIP protects progenitor cells against DNA damage in vivo.
Volume: 11
Issue: 10
Pages: 923
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Publication
32994318 | J:297493
 
First Author: Matos-Rodrigues GE
Year: 2020
Journal: Dis Model Mech
Title: Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome.
Volume: 13
Issue: 10
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Publication
28036033 | J:320282
 
First Author: Feng W
Year: 2016
Journal: Genes (Basel)
Title: Mec1/ATR, the Program Manager of Nucleic Acids Inc.
Volume: 8
Issue: 1
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Publication
29125140 | J:296112
First Author: Zhao B
Year: 2018
Journal: Cell Res
Title: Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.
Volume: 28
Issue: 1
Pages: 69-89
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22549958 | J:183982
First Author: Wojtasz L
Year: 2012
Journal: Genes Dev
Title: Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.
Volume: 26
Issue: 9
Pages: 958-73
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21693576 | J:183045
First Author: Refolio E
Year: 2011
Journal: J Cell Sci
Title: The Ddc2/ATRIP checkpoint protein monitors meiotic recombination intermediates.
Volume: 124
Issue: Pt 14
Pages: 2488-500
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23950734 | J:200981
First Author: Zhou ZW
Year: 2013
Journal: PLoS Genet
Title: An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.
Volume: 9
Issue: 8
Pages: e1003702
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22471438 | J:198034
First Author: Onksen JL
Year: 2012
Journal: Genes Brain Behav
Title: Running-induced anxiety is dependent on increases in hippocampal neurogenesis.
Volume: 11
Issue: 5
Pages: 529-38
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19805627 | J:153811
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
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26778124 | J:233038
First Author: Kibe T
Year: 2016
Journal: Mol Cell
Title: TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.
Volume: 61
Issue: 2
Pages: 236-46
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Publication
34158506 | J:343910
First Author: Li F
Year: 2021
Journal: Nat Commun
Title: The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation.
Volume: 12
Issue: 1
Pages: 3845
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22370720 | J:182697
First Author: López-Contreras AJ
Year: 2012
Journal: J Exp Med
Title: An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
Volume: 209
Issue: 3
Pages: 455-61
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19596237 | J:157331
First Author: Sfeir A
Year: 2009
Journal: Cell
Title: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Volume: 138
Issue: 1
Pages: 90-103
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22099311 | J:178606
First Author: Takai KK
Year: 2011
Journal: Mol Cell
Title: Telomere protection by TPP1/POT1 requires tethering to TIN2.
Volume: 44
Issue: 4
Pages: 647-59
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15589157 | J:95016
First Author: Turner JM
Year: 2004
Journal: Curr Biol
Title: BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.
Volume: 14
Issue: 23
Pages: 2135-42
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24142876 | J:202921
First Author: Ragland RL
Year: 2013
Journal: Genes Dev
Title: RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.
Volume: 27
Issue: 20
Pages: 2259-73
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21593482 | J:176702
First Author: Mu XF
Year: 2011
Journal: Biol Reprod
Title: DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.
Volume: 85
Issue: 3
Pages: 524-35
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15983387 | J:99862
First Author: Ishii H
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Volume: 102
Issue: 27
Pages: 9655-60
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19620979 | J:151542
First Author: Murga M
Year: 2009
Journal: Nat Genet
Title: A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging.
Volume: 41
Issue: 8
Pages: 891-8
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15998665 | J:100203
First Author: Bellani MA
Year: 2005
Journal: J Cell Sci
Title: SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.
Volume: 118
Issue: Pt 15
Pages: 3233-45
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22133876 | J:184414
First Author: Schoppy DW
Year: 2012
Journal: J Clin Invest
Title: Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.
Volume: 122
Issue: 1
Pages: 241-52
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Publication
21844338 | J:175235
First Author: Kawasumi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.
Volume: 108
Issue: 33
Pages: 13716-21
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24899707 | J:211631
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
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28620865 | J:309383
First Author: Kim J
Year: 2017
Journal: Histochem Cell Biol
Title: Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.
Volume: 148
Issue: 5
Pages: 489-501
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21478856 | J:173089
First Author: Daniel K
Year: 2011
Journal: Nat Cell Biol
Title: Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1.
Volume: 13
Issue: 5
Pages: 599-610
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18048416 | J:172169
First Author: El-Shemerly M
Year: 2008
Journal: Nucleic Acids Res
Title: ATR-dependent pathways control hEXO1 stability in response to stalled forks.
Volume: 36
Issue: 2
Pages: 511-9
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28851706 | J:263657
First Author: Lane SIR
Year: 2017
Journal: Development
Title: DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.
Volume: 144
Issue: 19
Pages: 3475-3486
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15680327 | J:96923
First Author: Park BJ
Year: 2005
Journal: Cell
Title: The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR.
Volume: 120
Issue: 2
Pages: 209-21
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18936156 | J:144553
First Author: He H
Year: 2009
Journal: Mol Cell Biol
Title: Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
Volume: 29
Issue: 1
Pages: 229-40
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23166357 | J:194086
First Author: Jung H
Year: 2012
Journal: J Exp Med
Title: RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry.
Volume: 209
Issue: 13
Pages: 2409-22
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29378830 | J:261621
 
First Author: Her J
Year: 2018
Journal: Mol Cell Biol
Title: 53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress.
Volume: 38
Issue: 8
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18089799 | J:130855
First Author: Armata HL
Year: 2007
Journal: Cancer Res
Title: The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression.
Volume: 67
Issue: 24
Pages: 11696-703
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26586427 | J:228143
First Author: Lee SS
Year: 2015
Journal: Cell Rep
Title: ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.
Volume: 13
Issue: 8
Pages: 1623-32
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15604234 | J:94951
First Author: Polci R
Year: 2004
Journal: Cancer Res
Title: NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response.
Volume: 64
Issue: 24
Pages: 8800-3
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Publication
31839538 | J:284005
First Author: Dokshin GA
Year: 2020
Journal: Dev Cell
Title: GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.
Volume: 52
Issue: 1
Pages: 53-68.e6
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30393076 | J:272558
First Author: Hirota T
Year: 2018
Journal: Dev Cell
Title: SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.
Volume: 47
Issue: 5
Pages: 645-659.e6
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Publication
27806302 | J:240893
First Author: Doksani Y
Year: 2016
Journal: Cell Rep
Title: Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining.
Volume: 17
Issue: 6
Pages: 1646-1656
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12937170 | J:86382
First Author: Yuan L
Year: 2003
Journal: J Biol Chem
Title: DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase.
Volume: 278
Issue: 44
Pages: 42812-20
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Publication
19531582 | J:153169
First Author: Kouznetsova A
Year: 2009
Journal: J Cell Sci
Title: BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.
Volume: 122
Issue: Pt 14
Pages: 2446-52
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26658019 | J:242195
First Author: Juan HC
Year: 2016
Journal: Cell Death Differ
Title: Cdk12 is essential for embryonic development and the maintenance of genomic stability.
Volume: 23
Issue: 6
Pages: 1038-48
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Publication
21522133 | J:173189
First Author: Ugalde AP
Year: 2011
Journal: EMBO J
Title: Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.
Volume: 30
Issue: 11
Pages: 2219-32
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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