Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2801 to 2848 out of 2848 for Pitx2

<< First < Previous | Next > Last >>

0.026s

Type

Details

Score

Allele

Hprt1<tm72(Ple158-lacZ)Ems> | MGI:4834888

Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 72, Elizabeth M Simpson
Allele Type:	Targeted

•

Genotype

Symbol:	Hand2/Hand2 Tg(Pitx2-cre)1Ych/?
Background:	involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Gsk3b/Gsk3b Tg(Pitx2-cre)1Ych/?
Background:	involves: 129S4/SvJaeSor * C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Rr52/Rr52
Background:	FVB-Rr52
Zygosity:	hm
Has Mutant Allele:	true

•

Allele

Pax6<tm2Pgr> | MGI:1934348

Name:	paired box 6; targeted mutation 2, Peter Gruss
Allele Type:	Targeted
Attribute String:	Conditional ready, No functional change

•

Genotype

Symbol:	Pax6<1Jrt>/Pax6<+>
Background:	C3.B6-Pax6<1Jrt>
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Pax6<3Neu>/Pax6<+>
Background:	either: (involves: 102 * C3H) or (involves: C3H)
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Pax6<4Neu>/Pax6<+>
Background:	either: (involves: 102 * C3H) or (involves: C3H)
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Pax6<7Neu>/Pax6<+>
Background:	involves: 102 * C3H
Zygosity:	ht
Has Mutant Allele:	true

•

DO Term

DOID:0060673 | Peters anomaly

•

Strain

MGI:4835717 | B6.129P2(Cg)-Hprt1<tm72(Ple158-lacZ)Ems>/Mmjax

Attribute String:

targeted mutation, mutant strain, congenic

•

Genotype

Symbol:	Hprt1/?
Background:	B6.129P2(Cg)-Hprt1/Mmjax
Zygosity:	ot
Has Mutant Allele:	true

•

Genotype

Symbol:	Pax6/Pax6<+> Tg(Pax6-cre,GFP)1Pgr/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

22939636 | -

First Author:	Kheradmand Kia S
Year:	2012
Journal:	Am J Hum Genet
Title:	RTTN mutations link primary cilia function to organization of the human cerebral cortex.
Volume:	91
Issue:	3
Pages:	533-40

•

Publication

32543652 | -

First Author:	Panda P
Year:	2020
Journal:	J Cell Biol
Title:	Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis.
Volume:	219
Issue:	8

•

Protein Domain

IPR030791 | Rotatin

Type:

Family

Description:

Rotatin (RTTN) is a centriolar protein that appears to be required for cilia function []. Mouse RTTN is required for embryonic axial rotation, and left-right specification. It is essential for the correct expression of the key left-right specification genes nodal, lefty and Pitx2 []. The Drosophila homologue of rotatin, Anastral spindle 3 (Ana3), is needed for structural integrity of centrioles and basal bodies []and participates in the later stages of centriole assembly through the interaction with Rcd4 leading to the centriole to centrosome conversion []. Rotatin colocalizes with the basal bodies at the primary cilium, and has a role in cilia structure and function []. Mutations in RTTN have been identified in individuals with polymicrogyria, a malformation of the developing cerebral cortex [].

•

HT Experiment

GSE22558 | Effects of a high-fat maternal diet and embryonic Cited2 genotype on gene expression and development in mouse


Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	GEO

•

Gene

1545 | CYP1B1

Type:	gene
Organism:	human

•

Publication

19948479 | -

First Author:	Stevens NR
Year:	2009
Journal:	J Cell Biol
Title:	Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies.
Volume:	187
Issue:	3
Pages:	355-63

•

Publication

11471154 | J:70219

First Author:	Hamada H
Year:	2001
Journal:	Am J Med Genet
Title:	Role of asymmetric signals in left-right patterning in the mouse.
Volume:	101
Issue:	4
Pages:	324-7

•

HT Experiment

E-GEOD-31583 | Lung of ECAT15-2/Dppa2 deficient embryo at E18.5

Series Id:	GSE31583
Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pitx2-cre/ERT2)#Jfm/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity:	cn
Has Mutant Allele:	true

•

Protein Coding Gene

MGI:97490 | Pax6

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Publication

26351675 | J:226902

First Author:	Hachisuga M
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	Hyperglycemia impairs left-right axis formation and thereby disturbs heart morphogenesis in mouse embryos.
Volume:	112
Issue:	38
Pages:	E5300-7

•

Publication

19341725 | J:149232

First Author:	Xiong W
Year:	2009
Journal:	Dev Biol
Title:	Hand2 is required in the epithelium for palatogenesis in mice.
Volume:	330
Issue:	1
Pages:	131-41

•

Publication

34245725 | J:310646

First Author:	Kahr PC
Year:	2021
Journal:	Dev Biol
Title:	A novel transgenic Cre allele to label mouse cardiac conduction system.
Volume:	478

Pages:	163-172

•

Protein

Q8R4Y8

Organism:	Mus musculus/domesticus
Length:	2226
Fragment?:	false

•

Publication

22233545 | J:182770

First Author:	Bisgrove BW
Year:	2012
Journal:	Dev Biol
Title:	RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow.
Volume:	363
Issue:	1
Pages:	166-78

•

Publication

25556186 | J:220601

First Author:	Gao S
Year:	2015
Journal:	Hum Mol Genet
Title:	TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: implications for 22q11.2 deletion syndrome.
Volume:	24
Issue:	8
Pages:	2330-48

•

Publication

28880281 | J:337259

First Author:	Ocaña OH
Year:	2017
Journal:	Nature
Title:	A right-handed signalling pathway drives heart looping in vertebrates.
Volume:	549
Issue:	7670
Pages:	86-90

•

Publication

17404238 | J:143020

First Author:	Rulifson IC
Year:	2007
Journal:	Proc Natl Acad Sci U S A
Title:	Wnt signaling regulates pancreatic beta cell proliferation.
Volume:	104
Issue:	15
Pages:	6247-52

•

Publication

31138678 | J:277773

First Author:	Figeac N
Year:	2019
Journal:	J Cell Sci
Title:	VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.
Volume:	132
Issue:	13

•

Publication

37703038 | J:340534

First Author:	Johnson LL
Year:	2023
Journal:	Invest Ophthalmol Vis Sci
Title:	Nystagmus Associated With the Absence of MYOD Expression Across the Lifespan in Extraocular and Limb Muscles.
Volume:	64
Issue:	12
Pages:	24

•

Publication

17848564 | J:126948

First Author:	Coulon V
Year:	2007
Journal:	J Biol Chem
Title:	A muscle-specific promoter directs Pitx3 gene expression in skeletal muscle cells.
Volume:	282
Issue:	45
Pages:	33192-200

•

Publication

22290435 | J:183690

First Author:	Curtis CD
Year:	2012
Journal:	Mol Cell Biol
Title:	The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling.
Volume:	32
Issue:	7
Pages:	1312-20

•

Publication

21504905 | J:173652

First Author:	Venugopalan SR
Year:	2011
Journal:	J Biol Chem
Title:	Hierarchical interactions of homeodomain and forkhead transcription factors in regulating odontogenic gene expression.
Volume:	286
Issue:	24
Pages:	21372-83

•

Publication

15556871 | J:219101

First Author:	Ernst P
Year:	2004
Journal:	Curr Biol
Title:	An Mll-dependent Hox program drives hematopoietic progenitor expansion.
Volume:	14
Issue:	22
Pages:	2063-9

•

Publication

18955041 | J:144078

First Author:	See AW
Year:	2009
Journal:	Dev Biol
Title:	The temporal requirement for vitamin A in the developing eye: mechanism of action in optic fissure closure and new roles for the vitamin in regulating cell proliferation and adhesion in the embryonic retina.
Volume:	325
Issue:	1
Pages:	94-105

•

Publication

22701669 | J:187837

First Author:	Jumlongras D
Year:	2012
Journal:	PLoS One
Title:	An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud.
Volume:	7
Issue:	6
Pages:	e38568

•

Publication

20981831 | J:166721

First Author:	He F
Year:	2010
Journal:	Dev Dyn
Title:	Gsk3β is required in the epithelium for palatal elevation in mice.
Volume:	239
Issue:	12
Pages:	3235-46

•

Publication

10469600 | J:57048

First Author:	Schneider A
Year:	1999
Journal:	Curr Biol
Title:	The homeobox gene NKX3.2 is a target of left-right signalling and is expressed on opposite sides in chick and mouse embryos.
Volume:	9
Issue:	16
Pages:	911-4

•

Publication

10512182 | J:60110

First Author:	Tsang TE
Year:	1999
Journal:	Cell Mol Biol (Noisy-le-grand)
Title:	Experimental analysis of the emergence of left-right asymmetry of the body axis in early postimplantation mouse embryos.
Volume:	45
Issue:	5
Pages:	493-503

•

Publication

22039477 | J:178084

First Author:	Kahr PC
Year:	2011
Journal:	PLoS One
Title:	Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue.
Volume:	6
Issue:	10
Pages:	e26389

•

Publication

26516282 | J:226610

First Author:	Bourane S
Year:	2015
Journal:	Science
Title:	Gate control of mechanical itch by a subpopulation of spinal cord interneurons.
Volume:	350
Issue:	6260
Pages:	550-4

•

Publication

18950699 | J:144244

First Author:	Yang GS
Year:	2009
Journal:	Genomics
Title:	Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.
Volume:	93
Issue:	3
Pages:	196-204

•

Publication

- | J:145689

First Author:	The Pleiades Promoter Project
Year:	2009
Journal:	MGI Direct Data Submission
Title:	Generation of reporter and cre-expressing targeted transgenic mice in the Hprt1 gene using human MiniPromoters that drive region- and cell-specific gene expression in the mouse brain

•

Publication

20807748 | J:164356

First Author:	Portales-Casamar E
Year:	2010
Journal:	Proc Natl Acad Sci U S A
Title:	A regulatory toolbox of MiniPromoters to drive selective expression in the brain.
Volume:	107
Issue:	38
Pages:	16589-94

•

Publication

- | J:100256

First Author:	The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year:	2005
Journal:	Database Download
Title:	MGI download of GENSAT transgene data

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do;jsessionid=89EDD2D94753DE83E39358662B1316BA?searchTerm=Pitx2&searchBag=&searchOffset=2800

MouseMine

Search our database by keyword

Examples

Search results 2801 to 2848 out of 2848 for Pitx2

Categories

Hits by Strain

Hits by Category