|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 936 for Parp1

0.05s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
First Author: Orsburn B
Year: 2010
Journal: Mol Cell Biol
Title: Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Volume: 30
Issue: 10
Pages: 2341-52
Publication  
First Author: Nelson MM
Year: 2021
Journal: Front Cell Dev Biol
Title: Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion.
Volume: 9
Pages: 693595
Publication
First Author: Kleppa L
Year: 2012
Journal: Nucleic Acids Res
Title: Kinetics of endogenous mouse FEN1 in base excision repair.
Volume: 40
Issue: 18
Pages: 9044-59
Publication
First Author: Lee SG
Year: 2020
Journal: EMBO Rep
Title: Ewing sarcoma protein promotes dissociation of poly(ADP-ribose) polymerase 1 from chromatin.
Volume: 21
Issue: 11
Pages: e48676
Publication
First Author: Zhang Y
Year: 2016
Journal: Am J Pathol
Title: Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury.
Volume: 186
Issue: 12
Pages: 3117-3130
Publication
First Author: Rybanska-Spaeder I
Year: 2014
Journal: PLoS One
Title: 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
Volume: 9
Issue: 9
Pages: e108731
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sallmann FR
Year: 2000
Journal: J Biol Chem
Title: Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.
Volume: 275
Issue: 20
Pages: 15504-11
Publication
First Author: Auer B
Year: 1995
Journal: Biochimie
Title: On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse.
Volume: 77
Issue: 6
Pages: 444-9
Publication
First Author: de Murcia G
Year: 1994
Journal: Trends Biochem Sci
Title: Poly(ADP-ribose) polymerase: a molecular nick-sensor.
Volume: 19
Issue: 4
Pages: 172-6
Publication
First Author: Masutani M
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes.
Volume: 96
Issue: 5
Pages: 2301-4
Publication
First Author: Shall S
Year: 2000
Journal: Mutat Res
Title: Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?
Volume: 460
Issue: 1
Pages: 1-15
Publication  
First Author: Fujihara H
Year: 2019
Journal: Cells
Title: Spontaneous Development of Dental Dysplasia in Aged Parp-1 Knockout Mice.
Volume: 8
Issue: 10
Publication
First Author: Nozaki T
Year: 2003
Journal: Cancer Sci
Title: Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane.
Volume: 94
Issue: 6
Pages: 497-500
Publication
First Author: Ogawa K
Year: 2006
Journal: Cancer Lett
Title: Parp-1 deficiency does not enhance liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline in mice.
Volume: 236
Issue: 1
Pages: 32-8
Publication
First Author: Masutani M
Year: 2000
Journal: Mutat Res
Title: The response of Parp knockout mice against DNA damaging agents.
Volume: 462
Issue: 2-3
Pages: 159-66
Publication
First Author: Gunji A
Year: 2006
Journal: Cancer Lett
Title: Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts.
Volume: 241
Issue: 1
Pages: 87-92
Publication
First Author: Shibata A
Year: 2009
Journal: Mutat Res
Title: Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age.
Volume: 664
Issue: 1-2
Pages: 20-7
Publication
First Author: Tsutsumi M
Year: 2001
Journal: Carcinogenesis
Title: Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity.
Volume: 22
Issue: 1
Pages: 1-3
Publication
First Author: Shibata A
Year: 2005
Journal: Oncogene
Title: Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent.
Volume: 24
Issue: 8
Pages: 1328-37
Publication
First Author: Osada T
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Poly(ADP-ribosylation) regulates chromatin organization through histone H3 modification and DNA methylation of the first cell cycle of mouse embryos.
Volume: 434
Issue: 1
Pages: 15-21
Publication
First Author: Nozaki T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Syncytiotrophoblastic giant cells in teratocarcinoma-like tumors derived from Parp-disrupted mouse embryonic stem cells.
Volume: 96
Issue: 23
Pages: 13345-50
Publication
First Author: Pétrilli V
Year: 2004
Journal: J Clin Invest
Title: Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice.
Volume: 114
Issue: 8
Pages: 1072-81
Publication
First Author: de Murcia JM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.
Volume: 94
Issue: 14
Pages: 7303-7
Publication
First Author: Dantzer F
Year: 1998
Journal: Nucleic Acids Res
Title: Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication.
Volume: 26
Issue: 8
Pages: 1891-8
Publication
First Author: Ambrose HE
Year: 2009
Journal: Immunology
Title: Poly(ADP-ribose) polymerase-1 (Parp-1)-deficient mice demonstrate abnormal antibody responses.
Volume: 127
Issue: 2
Pages: 178-86
Publication
First Author: Corral J
Year: 2005
Journal: Am J Pathol
Title: Role of lipopolysaccharide and cecal ligation and puncture on blood coagulation and inflammation in sensitive and resistant mice models.
Volume: 166
Issue: 4
Pages: 1089-98
Publication
First Author: Shi X
Year: 2007
Journal: Hear Res
Title: Expression of adhesion molecular proteins in the cochlear lateral wall of normal and PARP-1 mutant mice.
Volume: 224
Issue: 1-2
Pages: 1-14
Publication
First Author: Samper E
Year: 2001
Journal: J Cell Biol
Title: Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability.
Volume: 154
Issue: 1
Pages: 49-60
Publication
First Author: Trucco C
Year: 1999
Journal: Mol Cell Biochem
Title: A dual approach in the study of poly (ADP-ribose) polymerase: in vitro random mutagenesis and generation of deficient mice.
Volume: 193
Issue: 1-2
Pages: 53-60
Publication
First Author: Bai P
Year: 2011
Journal: Cell Metab
Title: PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.
Volume: 13
Issue: 4
Pages: 461-468
Publication
First Author: Nasta F
Year: 2010
Journal: J Immunol
Title: Increased Foxp3+ regulatory T cells in poly(ADP-Ribose) polymerase-1 deficiency.
Volume: 184
Issue: 7
Pages: 3470-7
Publication
First Author: Kanai M
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Haploinsufficiency of poly(ADP-ribose) polymerase-1-mediated poly(ADP-ribosyl)ation for centrosome duplication.
Volume: 359
Issue: 3
Pages: 426-30
Publication
First Author: Yélamos J
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Genetic and pharmacological inhibition of poly(ADP-ribose) polymerase-1 interferes in the chlamydial life cycle.
Volume: 324
Issue: 2
Pages: 840-8
Publication
First Author: Hempel C
Year: 2011
Journal: Am J Pathol
Title: CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.
Volume: 179
Issue: 4
Pages: 1939-50
Publication
First Author: Gonzalez C
Year: 2002
Journal: Diabetes
Title: Unexpected sensitivity of nonobese diabetic mice with a disrupted poly(ADP-Ribose) polymerase-1 gene to streptozotocin-induced and spontaneous diabetes.
Volume: 51
Issue: 5
Pages: 1470-6
Publication
First Author: Le Rhun Y
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase.
Volume: 245
Issue: 1
Pages: 1-10
Publication
First Author: Canitrot Y
Year: 1998
Journal: Nucleic Acids Res
Title: Decreased expression of topoisomerase IIbeta in poly(ADP-ribose) polymerase-deficient cells.
Volume: 26
Issue: 22
Pages: 5134-8
Publication
First Author: Oliver FJ
Year: 1998
Journal: J Biol Chem
Title: Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant.
Volume: 273
Issue: 50
Pages: 33533-9
Publication
First Author: Pu H
Year: 2014
Journal: Carcinogenesis
Title: PARP-1 regulates epithelial-mesenchymal transition (EMT) in prostate tumorigenesis.
Volume: 35
Issue: 11
Pages: 2592-601
Publication
First Author: Oumouna M
Year: 2006
Journal: J Immunol
Title: Poly(ADP-ribose) polymerase-1 inhibition prevents eosinophil recruitment by modulating Th2 cytokines in a murine model of allergic airway inflammation: a potential specific effect on IL-5.
Volume: 177
Issue: 9
Pages: 6489-96
Publication
First Author: Hu B
Year: 2013
Journal: Am J Pathol
Title: Regulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1.
Volume: 182
Issue: 1
Pages: 71-83
Publication
First Author: Zingarelli B
Year: 1999
Journal: Gastroenterology
Title: Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis.
Volume: 116
Issue: 2
Pages: 335-45
Publication
First Author: Boulares AH
Year: 2003
Journal: Am J Respir Cell Mol Biol
Title: Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma.
Volume: 28
Issue: 3
Pages: 322-9
Publication
First Author: Zingarelli B
Year: 1998
Journal: Circ Res
Title: Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury.
Volume: 83
Issue: 1
Pages: 85-94
Publication
First Author: Pillai JB
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Increased expression of poly(ADP-ribose) polymerase-1 contributes to caspase-independent myocyte cell death during heart failure.
Volume: 288
Issue: 2
Pages: H486-96
Publication
First Author: Ha HC
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia.
Volume: 99
Issue: 5
Pages: 3270-5
Publication
First Author: Obrosova IG
Year: 2008
Journal: Free Radic Biol Med
Title: PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy.
Volume: 44
Issue: 6
Pages: 972-81
Publication
First Author: Plane JM
Year: 2012
Journal: J Neurosci Res
Title: PARP-1 deletion promotes subventricular zone neural stem cells toward a glial fate.
Volume: 90
Issue: 8
Pages: 1489-506
Publication
First Author: Wang ZQ
Year: 1997
Journal: Genes Dev
Title: PARP is important for genomic stability but dispensable in apoptosis.
Volume: 11
Issue: 18
Pages: 2347-58
Publication
First Author: d'Adda di Fagagna F
Year: 1999
Journal: Nat Genet
Title: Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.
Volume: 23
Issue: 1
Pages: 76-80
Publication
First Author: Tentori L
Year: 2008
Journal: Eur J Cancer
Title: Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.
Volume: 44
Issue: 9
Pages: 1302-14
Publication
First Author: Khandoga A
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Poly(ADP-ribose) polymerase triggers the microvascular mechanisms of hepatic ischemia-reperfusion injury.
Volume: 283
Issue: 3
Pages: G553-60
Publication
First Author: Zerfaoui M
Year: 2009
Journal: J Leukoc Biol
Title: Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy Antigen Receptor for Chemokines.
Volume: 86
Issue: 6
Pages: 1385-92
Publication
First Author: Vagnerova K
Year: 2010
Journal: Neuroscience
Title: Poly (ADP-ribose) polymerase-1 initiated neuronal cell death pathway--do androgens matter?
Volume: 166
Issue: 2
Pages: 476-81
Publication
First Author: Nucci C
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Apoptosis in the dorsal lateral geniculate nucleus after monocular deprivation involves glutamate signaling, NO production, and PARP activation.
Volume: 278
Issue: 2
Pages: 360-7
Publication
First Author: Chiu LY
Year: 2021
Journal: FASEB J
Title: PARP-1 involves in UVB-induced inflammatory response in keratinocytes and skin injury via regulation of ROS-dependent EGFR transactivation and p38 signaling.
Volume: 35
Issue: 3
Pages: e21393
Publication
First Author: Kauppinen TM
Year: 2013
Journal: Biochim Biophys Acta
Title: Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
Volume: 1833
Issue: 8
Pages: 1985-91
Publication
First Author: Selvaraj V
Year: 2009
Journal: J Biol Chem
Title: PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis.
Volume: 284
Issue: 38
Pages: 26070-84
Publication
First Author: Shevalye H
Year: 2010
Journal: Biochim Biophys Acta
Title: Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease.
Volume: 1802
Issue: 11
Pages: 1020-7
Publication
First Author: Yang Z
Year: 2000
Journal: Shock
Title: Effect of genetic disruption of poly (ADP-ribose) synthetase on delayed production of inflammatory mediators and delayed necrosis during myocardial ischemia-reperfusion injury.
Volume: 13
Issue: 1
Pages: 60-6
Publication
First Author: Zhou HZ
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Poly(ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts.
Volume: 291
Issue: 2
Pages: H714-23
Publication
First Author: Mukhopadhyay P
Year: 2011
Journal: Free Radic Biol Med
Title: Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.
Volume: 51
Issue: 9
Pages: 1774-88
Publication  
First Author: Kam TI
Year: 2018
Journal: Science
Title: Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease.
Volume: 362
Issue: 6414
Publication
First Author: Zheng J
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Poly(ADP-ribose) polymerase-1 gene ablation protects mice from ischemic renal injury.
Volume: 288
Issue: 2
Pages: F387-98
Publication
First Author: Liaudet L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase.
Volume: 97
Issue: 18
Pages: 10203-8
Publication
First Author: Shieh WM
Year: 1998
Journal: J Biol Chem
Title: Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers.
Volume: 273
Issue: 46
Pages: 30069-72
Publication
First Author: Simbulan-Rosenthal CM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.
Volume: 96
Issue: 23
Pages: 13191-6
Publication
First Author: Pillai JB
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.
Volume: 291
Issue: 4
Pages: H1545-53
Publication
First Author: Jog NR
Year: 2009
Journal: J Immunol
Title: Poly(ADP-ribose) polymerase-1 regulates the progression of autoimmune nephritis in males by inducing necrotic cell death and modulating inflammation.
Volume: 182
Issue: 11
Pages: 7297-306
Publication
First Author: Eliasson MJ
Year: 1997
Journal: Nat Med
Title: Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
Volume: 3
Issue: 10
Pages: 1089-95
Publication
First Author: Andreone T
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Cytokine-mediated β-cell damage in PARP-1-deficient islets.
Volume: 303
Issue: 2
Pages: E172-9
Publication
First Author: Kühnle S
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Prevention of endotoxin-induced lethality, but not of liver apoptosis in poly(ADP-ribose) polymerase-deficient mice.
Volume: 263
Issue: 2
Pages: 433-8
Publication
First Author: Phulwani NK
Year: 2008
Journal: J Neurochem
Title: Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation.
Volume: 106
Issue: 2
Pages: 578-90
Publication
First Author: Kameoka M
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Poly(ADP-ribose)polymerase-1 is required for integration of the human immunodeficiency virus type 1 genome near centromeric alphoid DNA in human and murine cells.
Volume: 334
Issue: 2
Pages: 412-7
Publication
First Author: Cover C
Year: 2005
Journal: Toxicol Sci
Title: Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
Volume: 84
Issue: 1
Pages: 201-8
Publication
First Author: Lv S
Year: 2020
Journal: Int J Biol Sci
Title: 25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
Volume: 16
Issue: 2
Pages: 298-308
Publication
First Author: Pieper AA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.
Volume: 97
Issue: 4
Pages: 1845-50
Publication
First Author: Obrosova IG
Year: 2004
Journal: Diabetes
Title: Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.
Volume: 53
Issue: 3
Pages: 711-20
Publication
First Author: Zingarelli B
Year: 2004
Journal: Immunology
Title: Activator protein-1 signalling pathway and apoptosis are modulated by poly(ADP-ribose) polymerase-1 in experimental colitis.
Volume: 113
Issue: 4
Pages: 509-17
Publication
First Author: Erener S
Year: 2012
Journal: FASEB J
Title: ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation.
Volume: 26
Issue: 6
Pages: 2631-8
Publication
First Author: Pacher P
Year: 2002
Journal: J Pharmacol Exp Ther
Title: Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure.
Volume: 300
Issue: 3
Pages: 862-7