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Search results 1 to 100 out of 1167 for Ppara

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0.036s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression      
Probe: MGI:5634754
Assay Type: RT-PCR
Annotation Date: 2015-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5634753
Age: embryonic day 0.5
Specimen Label: Ppara
Detected: true
Specimen Num: 1
Publication
First Author: Aibara D
Year: 2022
Journal: iScience
Title: Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation.
Volume: 25
Issue: 5
Pages: 104196
Publication
First Author: Drosatos K
Year: 2016
Journal: Circ Res
Title: Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function.
Volume: 118
Issue: 2
Pages: 241-53
Publication
First Author: De Souza AT
Year: 2006
Journal: Nucleic Acids Res
Title: Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice.
Volume: 34
Issue: 16
Pages: 4486-94
Publication
First Author: Liu ZQ
Year: 2018
Journal: Autophagy
Title: Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo.
Volume: 14
Issue: 6
Pages: 1011-1027
Publication  
First Author: Kim D
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Keratin 79 is a PPARA target that is highly expressed by liver damage.
Volume: 650
Pages: 132-136
Publication
First Author: Brocker CN
Year: 2020
Journal: Nat Commun
Title: Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting.
Volume: 11
Issue: 1
Pages: 5847
Publication
First Author: Brocker CN
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells.
Volume: 312
Issue: 3
Pages: G283-G299
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191130
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ppara
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191130
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ppara
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191130
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ppara
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191130
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ppara
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191130
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ppara
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191130
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ppara
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6181050
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191130
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ppara
Detected: false
Specimen Num: 6
ncRNA Gene
Type: lncRNA_gene
Organism: mouse, laboratory
Publication
First Author: Bernal-Mizrachi C
Year: 2007
Journal: Cell Metab
Title: An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.
Volume: 5
Issue: 2
Pages: 91-102
Publication
First Author: Pan X
Year: 2018
Journal: J Lipid Res
Title: Oleoylethanolamide differentially regulates glycerolipid synthesis and lipoprotein secretion in intestine and liver.
Volume: 59
Issue: 12
Pages: 2349-2359
Publication
First Author: Djouadi F
Year: 1999
Journal: Prostaglandins Leukot Essent Fatty Acids
Title: The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism.
Volume: 60
Issue: 5-6
Pages: 339-43
Publication  
First Author: Li G
Year: 2018
Journal: Mol Metab
Title: Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha.
Volume: 7
Pages: 80-89
Publication
First Author: Saez E
Year: 2003
Journal: Nat Med
Title: Genetic deficiency in Pparg does not alter development of experimental prostate cancer.
Volume: 9
Issue: 10
Pages: 1265-6
Publication
First Author: Bernal-Mizrachi C
Year: 2003
Journal: Nat Med
Title: Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice.
Volume: 9
Issue: 8
Pages: 1069-75
Publication  
First Author: Szalowska E
Year: 2014
Journal: BMC Genomics
Title: Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.
Volume: 15
Pages: 1106
Publication
First Author: Tanaka N
Year: 2008
Journal: J Clin Invest
Title: PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice.
Volume: 118
Issue: 2
Pages: 683-94
Publication
First Author: Tam VC
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection.
Volume: 117
Issue: 27
Pages: 15789-15798
Publication  
First Author: Sáez-Orellana F
Year: 2021
Journal: JCI Insight
Title: Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.
Volume: 6
Issue: 16
Publication
First Author: Banke NH
Year: 2010
Journal: Circ Res
Title: Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.
Volume: 107
Issue: 2
Pages: 233-41
Publication
First Author: Lu Y
Year: 2014
Journal: J Clin Invest
Title: Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.
Volume: 124
Issue: 8
Pages: 3501-13
Publication
First Author: Harris IS
Year: 2004
Journal: Diabetes
Title: G-protein signaling participates in the development of diabetic cardiomyopathy.
Volume: 53
Issue: 12
Pages: 3082-90
Publication      
First Author: Paumelle R
Year: 2019
Journal: J Hepatol
Title: Hepatic PPARα is critical in the metabolic adaptation to sepsis.
Publication
First Author: Landowski M
Year: 2023
Journal: Commun Biol
Title: Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Volume: 6
Issue: 1
Pages: 8
Publication
First Author: Brocker CN
Year: 2018
Journal: J Lipid Res
Title: Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice.
Volume: 59
Issue: 11
Pages: 2140-2152
Publication
First Author: Gearing KL
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Structure of the mouse peroxisome proliferator activated receptor alpha gene.
Volume: 199
Issue: 1
Pages: 255-63
Publication
First Author: Horiguchi Y
Year: 2008
Journal: Biochem Biophys Res Commun
Title: 17beta-Hydroxysteroid dehydrogenase type 13 is a liver-specific lipid droplet-associated protein.
Volume: 370
Issue: 2
Pages: 235-8
Publication
First Author: Fu J
Year: 2003
Journal: Nature
Title: Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha.
Volume: 425
Issue: 6953
Pages: 90-3
Publication
First Author: Feng L
Year: 2017
Journal: J Lipid Res
Title: Identification and characterization of a novel PPARα-regulated and 7α-hydroxyl bile acid-preferring cytosolic sulfotransferase mL-STL (Sult2a8).
Volume: 58
Issue: 6
Pages: 1114-1131
Publication
First Author: Li S
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.
Volume: 305
Issue: 5
Pages: F618-27
Publication
First Author: Standage SW
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: PPARα augments heart function and cardiac fatty acid oxidation in early experimental polymicrobial sepsis.
Volume: 312
Issue: 2
Pages: H239-H249
Publication
First Author: Motojima K
Year: 1997
Journal: Biochem Biophys Res Commun
Title: PPAR alpha mediates peroxisome proliferator-induced transcriptional repression of nonperoxisomal gene expression in mouse.
Volume: 230
Issue: 1
Pages: 155-8
Publication
First Author: Benameur T
Year: 2010
Journal: PLoS One
Title: PPARalpha is essential for microparticle-induced differentiation of mouse bone marrow-derived endothelial progenitor cells and angiogenesis.
Volume: 5
Issue: 8
Pages: e12392
Publication
First Author: Hasmall S
Year: 2002
Journal: Toxicol Sci
Title: Downregulation of lactoferrin by PPARalpha ligands: role in perturbation of hepatocyte proliferation and apoptosis.
Volume: 68
Issue: 2
Pages: 304-13
Publication
First Author: Cheng R
Year: 2016
Journal: Diabetes
Title: Interaction of PPARα With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis.
Volume: 65
Issue: 12
Pages: 3730-3743
Publication
First Author: Lewitt MS
Year: 2002
Journal: Int J Obes Relat Metab Disord
Title: Gender difference in the leptin response to feeding in peroxisome-proliferator-activated receptor-alpha knockout mice.
Volume: 26
Issue: 10
Pages: 1296-300
Publication
First Author: Ding L
Year: 2014
Journal: Am J Pathol
Title: Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.
Volume: 184
Issue: 10
Pages: 2709-20
Publication
First Author: Kono K
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: PPAR{alpha} attenuates the proinflammatory response in activated mesangial cells.
Volume: 296
Issue: 2
Pages: F328-36
Publication
First Author: Neschen S
Year: 2007
Journal: Diabetes
Title: n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.
Volume: 56
Issue: 4
Pages: 1034-41
Publication
First Author: Li F
Year: 2012
Journal: J Lipid Res
Title: Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis.
Volume: 53
Issue: 8
Pages: 1625-35
Publication
First Author: Kaipainen A
Year: 2007
Journal: PLoS One
Title: PPARalpha deficiency in inflammatory cells suppresses tumor growth.
Volume: 2
Issue: 2
Pages: e260
Publication
First Author: Cole MA
Year: 2016
Journal: FASEB J
Title: On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.
Volume: 30
Issue: 8
Pages: 2684-97
Publication
First Author: Zhang MA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way.
Volume: 109
Issue: 24
Pages: 9505-10
Publication
First Author: Chang H
Year: 2019
Journal: Exp Cell Res
Title: PPARα suppresses Th17 cell differentiation through IL-6/STAT3/RORγt pathway in experimental autoimmune myocarditis.
Volume: 375
Issue: 1
Pages: 22-30
Publication
First Author: Panigrahy D
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.
Volume: 105
Issue: 3
Pages: 985-90
Publication
First Author: Al Kholaifi A
Year: 2008
Journal: Toxicol Sci
Title: Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARalpha.
Volume: 104
Issue: 1
Pages: 74-85
Publication
First Author: Saito H
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Regulatory mechanism governing the diurnal rhythm of intestinal H+/peptide cotransporter 1 (PEPT1).
Volume: 295
Issue: 2
Pages: G395-402
Publication
First Author: Le May C
Year: 2000
Journal: FEBS Lett
Title: Reduced hepatic fatty acid oxidation in fasting PPARalpha null mice is due to impaired mitochondrial hydroxymethylglutaryl-CoA synthase gene expression.
Volume: 475
Issue: 3
Pages: 163-6
Publication
First Author: Xu J
Year: 2002
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production.
Volume: 277
Issue: 52
Pages: 50237-44
Publication
First Author: Aoyama T
Year: 1998
Journal: J Biol Chem
Title: Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha).
Volume: 273
Issue: 10
Pages: 5678-84
Publication  
First Author: Freitas-Lima LC
Year: 2020
Journal: Int J Mol Sci
Title: PPAR-α Deletion Attenuates Cisplatin Nephrotoxicity by Modulating Renal Organic Transporters MATE-1 and OCT-2.
Volume: 21
Issue: 19
Publication
First Author: Ip E
Year: 2003
Journal: Hepatology
Title: Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.
Volume: 38
Issue: 1
Pages: 123-32
Publication
First Author: Kersten S
Year: 2001
Journal: FASEB J
Title: The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism.
Volume: 15
Issue: 11
Pages: 1971-8
Publication
First Author: Lee Y
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue.
Volume: 99
Issue: 18
Pages: 11848-53
Publication
First Author: Locci A
Year: 2019
Journal: Biol Psychiatry
Title: Stimulation of Peroxisome Proliferator-Activated Receptor-α by N-Palmitoylethanolamine Engages Allopregnanolone Biosynthesis to Modulate Emotional Behavior.
Volume: 85
Issue: 12
Pages: 1036-1045
Publication
First Author: Jones DC
Year: 2003
Journal: J Immunol
Title: Peroxisome proliferator-activated receptor alpha negatively regulates T-bet transcription through suppression of p38 mitogen-activated protein kinase activation.
Volume: 171
Issue: 1
Pages: 196-203
Publication
First Author: Harada Y
Year: 2016
Journal: Arch Toxicol
Title: PPARα-dependent cholesterol/testosterone disruption in Leydig cells mediates 2,4-dichlorophenoxyacetic acid-induced testicular toxicity in mice.
Volume: 90
Issue: 12
Pages: 3061-3071
Publication
First Author: Chung KW
Year: 2018
Journal: J Am Soc Nephrol
Title: Impairment of PPARα and the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging.
Volume: 29
Issue: 4
Pages: 1223-1237
Publication
First Author: Anderson SP
Year: 2002
Journal: Hepatology
Title: Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice.
Volume: 36
Issue: 3
Pages: 544-54
Publication
First Author: Cotter DG
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.
Volume: 307
Issue: 2
Pages: E176-85
Publication
First Author: Yessoufou A
Year: 2006
Journal: Endocrinology
Title: Peroxisome proliferator-activated receptor alpha deficiency increases the risk of maternal abortion and neonatal mortality in murine pregnancy with or without diabetes mellitus: Modulation of T cell differentiation.
Volume: 147
Issue: 9
Pages: 4410-8
Publication
First Author: Kersten S
Year: 1999
Journal: J Clin Invest
Title: Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting.
Volume: 103
Issue: 11
Pages: 1489-98
Publication
First Author: Li G
Year: 2017
Journal: Cell Metab
Title: Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.
Volume: 26
Issue: 4
Pages: 672-685.e4
Publication
First Author: Villard PH
Year: 2007
Journal: Biochem Biophys Res Commun
Title: PPARalpha transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects.
Volume: 364
Issue: 4
Pages: 896-901
Publication
First Author: Panagia M
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia.
Volume: 288
Issue: 6
Pages: H2677-83
Publication
First Author: Abbott BD
Year: 2007
Journal: Toxicol Sci
Title: Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.
Volume: 98
Issue: 2
Pages: 571-81
Publication
First Author: Ijssennagger N
Year: 2012
Journal: PLoS One
Title: Dietary heme-mediated PPARα activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon.
Volume: 7
Issue: 8
Pages: e43260
Publication
First Author: Dallongeville J
Year: 2001
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor alpha is not rate-limiting for the lipoprotein-lowering action of fish oil.
Volume: 276
Issue: 7
Pages: 4634-9
Publication
First Author: Lindén D
Year: 2001
Journal: J Lipid Res
Title: PPARalpha deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins.
Volume: 42
Issue: 11
Pages: 1831-40
Publication
First Author: Mazzon E
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of peroxisome proliferator-activated receptor-alpha in ileum tight junction alteration in mouse model of restraint stress.
Volume: 297
Issue: 3
Pages: G488-505
Publication
First Author: Loichot C
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Deletion of peroxisome proliferator-activated receptor-alpha induces an alteration of cardiac functions.
Volume: 291
Issue: 1
Pages: H161-6
Publication
First Author: Walker CG
Year: 2007
Journal: J Endocrinol
Title: Peroxisome proliferator-activated receptor alpha deficiency modifies glucose handling by isolated mouse adipocytes.
Volume: 193
Issue: 1
Pages: 39-43
Publication
First Author: Ljungberg A
Year: 2007
Journal: Growth Horm IGF Res
Title: Importance of PPAR alpha for the effects of growth hormone on hepatic lipid and lipoprotein metabolism.
Volume: 17
Issue: 2
Pages: 154-64
Publication  
First Author: Rosen MB
Year: 2017
Journal: Toxicology
Title: PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.
Volume: 387
Pages: 95-107
Publication
First Author: Ruiz-Medina J
Year: 2012
Journal: Psychopharmacology (Berl)
Title: Alteration of neuropathic and visceral pain in female C57BL/6J mice lacking the PPAR-α gene.
Volume: 222
Issue: 3
Pages: 477-88
Publication  
First Author: Kondo Y
Year: 2020
Journal: Physiol Behav
Title: Sleep profile during fasting in PPAR-alpha knockout mice.
Volume: 214
Pages: 112760
Publication
First Author: Ringseis R
Year: 2013
Journal: Biochim Biophys Acta
Title: Treatment with pharmacological PPARα agonists stimulates the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents.
Volume: 1830
Issue: 1
Pages: 2105-17
Publication  
First Author: Gibbons GF
Year: 2002
Journal: Adv Enzyme Regul
Title: The functional efficiency of lipogenic and cholesterogenic gene expression in normal mice and in mice lacking the peroxisomal proliferator-activated receptor-alpha (PPAR-alpha).
Volume: 42
Pages: 227-47
Publication
First Author: Peters JM
Year: 2001
Journal: Biochim Biophys Acta
Title: Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice.
Volume: 1533
Issue: 3
Pages: 233-42
Publication
First Author: Howroyd P
Year: 2004
Journal: Toxicol Pathol
Title: Decreased longevity and enhancement of age-dependent lesions in mice lacking the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).
Volume: 32
Issue: 5
Pages: 591-9
Publication
First Author: Ziouzenkova O
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase.
Volume: 100
Issue: 5
Pages: 2730-5
Publication
First Author: Chen C
Year: 2000
Journal: Toxicol Sci
Title: Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure.
Volume: 57
Issue: 2
Pages: 338-44
Publication
First Author: Di Paola R
Year: 2012
Journal: J Leukoc Biol
Title: Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice.
Volume: 91
Issue: 6
Pages: 911-20
Publication
First Author: Kamijo Y
Year: 2007
Journal: J Am Soc Nephrol
Title: PPARalpha protects proximal tubular cells from acute fatty acid toxicity.
Volume: 18
Issue: 12
Pages: 3089-100