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Search results 201 to 216 out of 216 for Ppp1ca

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0.018s

Type

Details

Score

Protein

Q9D8C8

Organism:	Mus musculus/domesticus
Length:	260
Fragment?:	false

•

Protein

F6XYC5

Organism:	Mus musculus/domesticus
Length:	144
Fragment?:	true

•

Publication

29335436 | J:257713

First Author:	Chen M
Year:	2018
Journal:	Nat Commun
Title:	Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.
Volume:	9
Issue:	1
Pages:	159

•

Protein Domain

IPR037981 | PPP1CC

Type:

Family

Description:

Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [, , ]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].This entry includes the catalytic subunit gamma (PPP1CC) from mammals, Dis2 from fission yeasts and Glc7 from budding yeasts. Glc7 is also a component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB [].

•

Publication

21598252 | J:175264

First Author:	Molina-Pinelo S
Year:	2011
Journal:	J Pathol
Title:	Down-regulation of spinophilin in lung tumours contributes to tumourigenesis.
Volume:	225
Issue:	1
Pages:	73-82

•

Publication

26334248 | J:229419

First Author:	Liu R
Year:	2015
Journal:	J Mol Cell Cardiol
Title:	Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.
Volume:	87

Pages:	204-13

•

Publication

25001178 | J:213851

First Author:	Banzhaf-Strathmann J
Year:	2014
Journal:	EMBO J
Title:	MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.
Volume:	33
Issue:	15
Pages:	1667-80

•

Publication

30948508 | J:280519

First Author:	Addison WN
Year:	2019
Journal:	J Biol Chem
Title:	Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.
Volume:	294
Issue:	20
Pages:	8184-8196

•

Publication

19389623 | -

First Author:	Hendrickx A
Year:	2009
Journal:	Chem Biol
Title:	Docking motif-guided mapping of the interactome of protein phosphatase-1.
Volume:	16
Issue:	4
Pages:	365-71

•

Protein

P63087

Organism:	Mus musculus/domesticus
Length:	323
Fragment?:	false

•

Protein

Q3U7K1

Organism:	Mus musculus/domesticus
Length:	323
Fragment?:	false

•

Protein

A0A0G2JFF1

Organism:	Mus musculus/domesticus
Length:	292
Fragment?:	true

•

Protein

A0A0G2JGC1

Organism:	Mus musculus/domesticus
Length:	273
Fragment?:	false

•

Protein

Q6ZWM8

Organism:	Mus musculus/domesticus
Length:	323
Fragment?:	false

•

Publication

12819204 | -

First Author:	Nedea E
Year:	2003
Journal:	J Biol Chem
Title:	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.
Volume:	278
Issue:	35
Pages:	33000-10

•

Publication

- | J:100256

First Author:	The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year:	2005
Journal:	Database Download
Title:	MGI download of GENSAT transgene data

•

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