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Search results 101 to 192 out of 192 for Fmo5

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0.048s
Type Details Score
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1781522
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759722
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672722
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274122
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1624622
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Note: Expression was not detected in the digestive system.
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428666
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422689
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EB3440; Specimen B707
Detected: false
Specimen Num: 1
Publication
First Author: Veeravalli S
Year: 2020
Journal: Drug Metab Dispos
Title: Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.
Volume: 48
Issue: 5
Pages: 378-385
Publication
First Author: Yu Z
Year: 2009
Journal: EMBO J
Title: The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation.
Volume: 28
Issue: 13
Pages: 1890-903
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Overby LH
Year: 1995
Journal: Arch Biochem Biophys
Title: Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog.
Volume: 317
Issue: 1
Pages: 275-84
Protein Domain
Type: Family
Description: Flavin-containing monooxygenases (FMOs) constitute a family of xenobiotic-metabolising enzymes []. Using an NADPH cofactor and FAD prosthetic group,these microsomal proteins catalyse the oxygenation of nucleophilic nitrogen,sulphur, phosphorous and selenium atoms in a range of structurally diversecompounds. Five mammalian forms of FMO are now known and have been designatedFMO1-FMO5 [, , , , ].The deduced amino acid sequence of human FM05 includes the putative FAD- (GxGxxG) and NADP+pyrophosphate-binding (GxGxxA) sites characteristic of mammalian FMOs [], a 'FATGY' motif that has also been observed in a rangeof siderphore biosynthetic enzymes [], and a C-terminal hydrophobic segmentthat is believed to anchor the monooxygenase to the microsomal membrane [].Human and guinea pig FMO5, like other FMOs, are encoded by multipletranscripts. FMO5 has been identified in livers of adult humans, rabbitsand guinea pigs, and foetal livers of humans []. Neither the human nor guinea pig enzyme effectively catalyse the metabolism of methimazole, ageneral FMO substrate; however, both are active with n-octylamine []. Theresponses to detergent, ions and elevated temperature are all similar to those observed in rabbit FMO5, suggesting that these properties are species-independent and that this form of FMO is not readily classified as a drug-metabolising enzyme [].
Publication
First Author: Falls JG
Year: 1997
Journal: Arch Biochem Biophys
Title: Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids.
Volume: 342
Issue: 2
Pages: 212-23
Protein
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
Publication
First Author: Ozols J
Year: 1990
Journal: J Biol Chem
Title: Covalent structure of liver microsomal flavin-containing monooxygenase form 1.
Volume: 265
Issue: 18
Pages: 10289-99
Publication
First Author: Stehr M
Year: 1998
Journal: Trends Biochem Sci
Title: A hydrophobic sequence motif common to N-hydroxylating enzymes.
Volume: 23
Issue: 2
Pages: 56-7
Publication
First Author: Lawton MP
Year: 1994
Journal: Arch Biochem Biophys
Title: A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.
Volume: 308
Issue: 1
Pages: 254-7
Publication  
First Author: Dolphin CT
Year: 1992
Journal: Biochem J
Title: Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.
Volume: 287 ( Pt 1)
Pages: 261-7
Publication
First Author: Lawton MP
Year: 1990
Journal: J Biol Chem
Title: The flavin-containing monooxygenase enzymes expressed in rabbit liver and lung are products of related but distinctly different genes.
Volume: 265
Issue: 10
Pages: 5855-61
Publication
First Author: Dolphin C
Year: 1991
Journal: J Biol Chem
Title: Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1).
Volume: 266
Issue: 19
Pages: 12379-85
Publication
First Author: Atta-Asafo-Adjei E
Year: 1993
Journal: J Biol Chem
Title: Cloning, sequencing, distribution, and expression in Escherichia coli of flavin-containing monooxygenase 1C1. Evidence for a third gene subfamily in rabbits.
Volume: 268
Issue: 13
Pages: 9681-9
Publication
First Author: Lomri N
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.
Volume: 89
Issue: 5
Pages: 1685-9