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Search results 301 to 368 out of 368 for Brpf1

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0.022s
Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
GXD Expression    
Probe: MGI:6719603
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447095
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446967
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447096
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446968
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447097
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446969
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447098
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446970
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447099
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446971
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447100
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446972
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447101
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446973
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447102
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446974
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447105
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446975
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447107
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446976
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447108
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7446977
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447109
Age: embryonic day 8.75
Image: 9
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447021
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447111
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447022
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447112
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447023
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447113
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447024
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447114
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447025
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447115
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447027
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447116
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447028
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447117
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447030
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447118
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447031
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447119
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447032
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447120
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447033
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447121
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447034
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447122
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447035
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447123
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447036
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447124
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447037
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447125
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447038
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447127
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447039
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447128
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447040
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447129
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447041
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447130
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447042
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7447131
Age: embryonic day 8.75
Specimen Label: Brpf1 delta/delta
Detected: true
Specimen Num: 2
Publication
First Author: Laue K
Year: 2008
Journal: Development
Title: The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity.
Volume: 135
Issue: 11
Pages: 1935-46
Publication
First Author: Klein BJ
Year: 2016
Journal: Nucleic Acids Res
Title: Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Volume: 44
Issue: 1
Pages: 472-84
HT Experiment
Series Id: E-GEOD-83483
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Barcikowski S
Year: 1984
Journal: Pol Tyg Lek
Title: [Heterotopic autotransplantation of the spleen-splenosis].
Volume: 39
Issue: 24
Pages: 841-3
Publication
First Author: Thompson KA
Year: 1994
Journal: Biochem Biophys Res Commun
Title: BR140, a novel zinc-finger protein with homology to the TAF250 subunit of TFIID.
Volume: 198
Issue: 3
Pages: 1143-52
Protein Domain
Type: Domain
Description: The PWWP domain is found in the BR140 family, which includes peregrine (also known as protein BR140 or Brpf1) and BR140-like proteins 1 and 2 (Bromodomain and PHD finger-containing proteins 2 and 3). BR140 is the only family to contain the PWWP domain at the C terminus, with PHD and bromo domains in the N-terminal region. Brpf1 is part of the MOZ/MORF complex which has a histone H3 acetyltransferase activity [, ]. The PWWP domain of Brpf1 has been shown to bind H3K36me3 [].The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins seem to be nuclear, often DNA-binding proteins, that function as transcription factors regulating a variety of developmental processes [].
Protein Domain
Type: Domain
Description: This entry represents the ePHD finger of Peregrin (also known as BRPF1), which is a multi-domain protein that binds histones, mediates monocytic leukemic zinc-finger protein (MOZ) -dependent histone acetylation, and is required for Hox gene expression and segmental identity []. It is a close partner of the MOZ histone acetyltransferase (HAT) complex and a novel Trithorax group (TrxG) member with a central role during development [, ]. BRPF1 is primarily a nuclear protein that has a broad tissue distribution and is abundant in testes and spermatogonia. It contains a plant homeodomain (PHD) zinc finger followed by a non-canonical ePHD finger, a bromodomain and a proline-tryptophan-tryptophan-proline (PWWP) domain. This PHD finger binds to methylated lysine 4 of histone H3 (H3K4me), the bromodomain interacts with acetylated lysines on N-terminal tails of histones and other proteins, and the PWWP domain shows histone-binding and chromatin association properties. BRPF1 may be involved in chromatin remodeling. The extended plant homeodomain (ePHD) zinc finger is characterized as Cys2HisCys5HisCys2His [, ].
Protein Domain
Type: Domain
Description: This entry represents the PHD finger of BRPF1. BRPF1, also termed peregrin, or protein Br140, is a multi-domain protein that binds histones, mediates monocytic leukemic zinc-finger protein (MOZ) -dependent histone acetylation, and is required for Hox gene expression and segmental identity []. It is a close partner of the MOZ histone acetyltransferase (HAT) complex and a novel Trithorax group (TrxG) member with a central role during development [, ]. BRPF1 is primarily a nuclear protein that has a broad tissue distribution and is abundant in testes and spermatogonia []. It contains a plant homeodomain (PHD) zinc finger followed by a non-canonical ePHD finger, a bromodomain and a proline-tryptophan-tryptophan-proline (PWWP) domain. PHD and ePHD fingers both bind to lysine 4 of histone H3 (K4H3), bromodomains interact with acetylated lysines on N-terminal tails of histones and other proteins, and PWWP domains show histone-binding and chromatin association properties. BRPF1 may be involved in chromatin remodeling [, ].
Publication
First Author: Hibiya K
Year: 2009
Journal: Dev Biol
Title: Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons.
Volume: 329
Issue: 2
Pages: 176-90
Protein Domain
Type: Domain
Description: This entry represents the ePHD finger of BRPF3. BRF3 is a homologue of BRPF1 and BRPF2. The extended plant homeodomain (ePHD) zinc finger is characterized as Cys2HisCys5HisCys2His. BRPF3 is a scaffold protein that forms a novel monocytic leukemic zinc finger protein (MOZ)/MOZ-related factor (MORF) H3 histone acetyltransferase (HAT) complex with other regulatory subunits []. BRPF3 contains a plant homeodomain (PHD) finger followed by this non-canonical ePHD finger, a bromodomain, and a proline-tryptophan-tryptophan-proline (PWWP) domain [].
Publication
First Author: Wu H
Year: 2011
Journal: PLoS One
Title: Structural and histone binding ability characterizations of human PWWP domains.
Volume: 6
Issue: 6
Pages: e18919
Publication
First Author: Vezzoli A
Year: 2010
Journal: Nat Struct Mol Biol
Title: Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1.
Volume: 17
Issue: 5
Pages: 617-9
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 376  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: true
Publication
First Author: Mishima Y
Year: 2011
Journal: Blood
Title: The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.
Volume: 118
Issue: 9
Pages: 2443-53
Publication
First Author: Ishikura S
Year: 2016
Journal: Biochim Biophys Acta
Title: Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.
Volume: 1859
Issue: 11
Pages: 1398-1410
Publication
First Author: Ullah M
Year: 2008
Journal: Mol Cell Biol
Title: Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.
Volume: 28
Issue: 22
Pages: 6828-43
Publication
First Author: Stec I
Year: 2000
Journal: FEBS Lett
Title: The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?
Volume: 473
Issue: 1
Pages: 1-5
Protein
Organism: Mus musculus/domesticus
Length: 1212  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1252  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1219  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1118  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1246  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 807  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 870  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1058  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 792  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7