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Search results 101 to 111 out of 111 for Trim68

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0.02s

Type

Details

Score

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

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UniProt Feature

Begin:	1
Description:	E3 ubiquitin-protein ligase TRIM68
Type:	chain
End:	485

•

Protein

A0A1B0GSL9

Organism:	Mus musculus/domesticus
Length:	327
Fragment?:	false

•

Protein

G3X9I6

Organism:	Mus musculus/domesticus
Length:	485
Fragment?:	false

•

Publication

18451177 | -

First Author:	Miyajima N
Year:	2008
Journal:	Cancer Res
Title:	TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells.
Volume:	68
Issue:	9
Pages:	3486-94

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Publication

24999993 | -

First Author:	Wynne C
Year:	2014
Journal:	PLoS One
Title:	TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.
Volume:	9
Issue:	7
Pages:	e101503

•

Publication

11560955 | -

First Author:	Billaut-Mulot O
Year:	2001
Journal:	J Clin Invest
Title:	SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus.
Volume:	108
Issue:	6
Pages:	861-9

•

Publication

19212346 | -

First Author:	Baek Sørensen R
Year:	2009
Journal:	J Invest Dermatol
Title:	Melanoma inhibitor of apoptosis protein (ML-IAP) specific cytotoxic T lymphocytes cross-react with an epitope from the auto-antigen SS56.
Volume:	129
Issue:	8
Pages:	1992-9

•

Protein Domain

IPR042656 | TRIM68_RING-HC

Type:

Domain

Description:

TRIM68 is an E3 ubiquitin-protein ligase that negatively regulates Toll-like receptor (TLR)- and RIG-I-like receptor (RLR)-driven type I interferon production by degrading TRK fused gene (TFG), a novel driver of IFN-beta downstream of anti-viral detection systems []. It also functions as a cofactor for androgen receptor-mediated transcription through regulating ligand-dependent transcription of androgen receptor in prostate cancer cells []. Moreover, TRIM68 is a cellular target of autoantibody responses in Sjogren"s syndrome (SS), as well as systemic lupus erythematosus (SLE). It is also an auto-antigen for T cells in SS and SLE [, ]. TRIM68 belongs the C-IV subclass of TRIM (tripartite motif) family of proteins that are defined by their N-terminal RBCC (RING, Bbox, and coiled coil) domains, including three consecutive zinc-binding domains, a C3HC4-type RING-HC finger, a B-box, and two coiled coil domains, as well as a B30.2/SPRY (SplA and ryanodine receptor) domain positioned C-terminal to the RBCC domain. This entry represents the C3HC4-type RING-HC finger found in TRIM68.

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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