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Search results 101 to 152 out of 152 for Astn1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4462464
Assay Type: RNA in situ
Annotation Date: 2010-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462477
Age: postnatal day 6
Image: 2K
Specimen Label: 2K
Detected: true
Specimen Num: 1
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Publication
15520881 | J:93967
First Author: Cheung CC
Year: 2004
Journal: Mamm Genome
Title: Quantitative trait loci for steady-state platelet count in mice.
Volume: 15
Issue: 10
Pages: 784-97
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Publication
10444330 | J:54765
First Author: Bergstrom DE
Year: 1999
Journal: Genomics
Title: Genetic and physical mapping of the dreher locus on mouse chromosome 1.
Volume: 59
Issue: 3
Pages: 291-9
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Publication
27452274 | J:258293
 
First Author: Divya TS
Year: 2016
Journal: Sci Rep
Title: Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development.
Volume: 6
Pages: 30337
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Publication
20151419 | J:162273
First Author: Faux C
Year: 2010
Journal: J Comp Neurol
Title: Differential gene expression in migrating cortical interneurons during mouse forebrain development.
Volume: 518
Issue: 8
Pages: 1232-48
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Publication
30250269 | J:279065
First Author: Liu W
Year: 2018
Journal: Cell Death Dis
Title: MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development.
Volume: 9
Issue: 10
Pages: 999
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Publication
21800304 | J:187345
First Author: Piper M
Year: 2011
Journal: J Comp Neurol
Title: Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum.
Volume: 519
Issue: 17
Pages: 3532-48
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Publication
12465718 | J:86755
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
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Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR026995 | Astrotactin
Type: Family
Description: Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Protein Domain
IPR045575 | ASTN_1_2_N
Type: Domain
Description: This entry represents the N-terminal domain of ASTN1/2. This domain includes the transmembrane and cytosolic regions [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Protein
A0A0A6YWD1
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
A0A0A6YWJ9
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein Domain
IPR045574 | ASTN1_2_EGF_Fn
Type: Domain
Description: This domain localises to the middle of the C-terminal region of ASTN1 and 2, which comprises a EGF- like domain (EGF4) and a fibronectin type III (Fn(III)) domain []. These subdomains are located between the MACPF and annexin-like domains. The structure of Fn(III) from ASTN2 revealed an unexpected feature which has two additional beta strands folded across the core. The junction between EGF-4 and Fn(III) domains in ASTN2 (but not in ASTN1) is thought to be an inositol triphosphate binding site [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Publication
27249642 | -
 
First Author: Ni T
Year: 2016
Journal: Open Biol
Title: Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Volume: 6
Issue: 5
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Protein
A0A0A6YXJ4
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Protein
Q3TPU9
Organism: Mus musculus/domesticus
Length: 840  
Fragment?: false
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Publication
30242134 | J:266179
First Author: Behesti H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.
Volume: 115
Issue: 41
Pages: E9717-E9726
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Protein
A0A0A6YVT7
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
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Protein
Q61137
Organism: Mus musculus/domesticus
Length: 1302  
Fragment?: false
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Protein
Q80Z10
Organism: Mus musculus/domesticus
Length: 1352  
Fragment?: false
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Protein
Q9QY74
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: false
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Protein
Q3UHD7
Organism: Mus musculus/domesticus
Length: 1294  
Fragment?: false
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Protein
A0A0A6YWE6
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
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Protein
Q8BRX1
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: false
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Publication
27042284 | J:231288
 
First Author: Berkowicz SR
Year: 2016
Journal: Mol Autism
Title: Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
Volume: 7
Pages: 22
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Publication
31169361 | J:292826
First Author: Hirose H
Year: 2019
Journal: Chembiochem
Title: A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.
Volume: 20
Issue: 16
Pages: 2089-2100
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Publication
28100779 | J:241080
First Author: Chang H
Year: 2017
Journal: J Biol Chem
Title: Intramembrane Proteolysis of Astrotactins.
Volume: 292
Issue: 8
Pages: 3506-3516
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Publication
35729251 | J:326584
First Author: Delpero M
Year: 2022
Journal: Sci Rep
Title: QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease.
Volume: 12
Issue: 1
Pages: 10471
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