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Search results 201 to 300 out of 1952 for Ins2

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Type Details Score
Publication
22015457 | J:180271
First Author: Zou MH
Year: 2011
Journal: Am J Pathol
Title: Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.
Volume: 179
Issue: 6
Pages: 2835-44
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Publication
23820623 | J:203191
First Author: Mitchell T
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells.
Volume: 305
Issue: 5
Pages: E585-99
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Publication
36172176 | J:329248
 
First Author: Zerbini G
Year: 2022
Journal: Front Pharmacol
Title: Topical nerve growth factor prevents neurodegenerative and vascular stages of diabetic retinopathy.
Volume: 13
Pages: 1015522
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Publication
21840999 | J:176719
First Author: Dennis MD
Year: 2011
Journal: J Biol Chem
Title: Hyperglycemia-induced O-GlcNAcylation and truncation of 4E-BP1 protein in liver of a mouse model of type 1 diabetes.
Volume: 286
Issue: 39
Pages: 34286-97
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Publication
23404117 | J:214916
First Author: Murray AR
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: MicroRNA-200b downregulates oxidation resistance 1 (Oxr1) expression in the retina of type 1 diabetes model.
Volume: 54
Issue: 3
Pages: 1689-97
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Publication
19470681 | J:309661
First Author: Fujita H
Year: 2009
Journal: J Am Soc Nephrol
Title: Reduction of renal superoxide dismutase in progressive diabetic nephropathy.
Volume: 20
Issue: 6
Pages: 1303-13
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19880509 | J:158307
First Author: Hodish I
Year: 2010
Journal: J Biol Chem
Title: Misfolded proinsulin affects bystander proinsulin in neonatal diabetes.
Volume: 285
Issue: 1
Pages: 685-94
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Publication
30480744 | J:267368
First Author: You ZP
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Bioinformatics Analysis of Weighted Genes in Diabetic Retinopathy.
Volume: 59
Issue: 13
Pages: 5558-5563
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Publication
16118394 | J:104083
First Author: Gurley SB
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Impact of genetic background on nephropathy in diabetic mice.
Volume: 290
Issue: 1
Pages: F214-22
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Publication
12540615 | J:107156
First Author: Izumi T
Year: 2003
Journal: Diabetes
Title: Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse.
Volume: 52
Issue: 2
Pages: 409-16
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Publication
31914588 | J:292458
First Author: Bhedi CD
Year: 2020
Journal: FASEB J
Title: Glycolysis regulated transglutaminase 2 activation in cardiopulmonary fibrogenic remodeling.
Volume: 34
Issue: 1
Pages: 930-944
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Publication
26597883 | J:228139
First Author: Venegas-Pino DE
Year: 2016
Journal: Am J Pathol
Title: Sex-Specific Differences in an ApoE(-/-):Ins2(+/Akita) Mouse Model of Accelerated Atherosclerosis.
Volume: 186
Issue: 1
Pages: 67-77
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Publication
23734074 | J:203213
 
First Author: Gurel Z
Year: 2013
Journal: Mol Vis
Title: Retinal O-linked N-acetylglucosamine protein modifications: implications for postnatal retinal vascularization and the pathogenesis of diabetic retinopathy.
Volume: 19
Pages: 1047-59
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Publication
23661372 | J:215435
First Author: Wang Y
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway.
Volume: 54
Issue: 5
Pages: 3806-14
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Publication
25207540 | J:213912
First Author: Soto I
Year: 2014
Journal: PLoS One
Title: DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.
Volume: 9
Issue: 9
Pages: e107291
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Publication
22653270 | J:186435
First Author: Liu GC
Year: 2012
Journal: Diabetologia
Title: Deletion of p47phox attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse.
Volume: 55
Issue: 9
Pages: 2522-32
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31311313 | J:294197
First Author: Liu S
Year: 2019
Journal: FASEB J
Title: Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells.
Volume: 33
Issue: 10
Pages: 11338-11348
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Publication
22610174 | J:189027
First Author: LaRocca TJ
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway.
Volume: 303
Issue: 3
Pages: H353-67
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Publication
29875100 | J:264039
First Author: Vastani N
Year: 2018
Journal: Diabetes
Title: Impaired Nociception in the Diabetic Ins2+/Akita Mouse.
Volume: 67
Issue: 8
Pages: 1650-1662
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Publication
24247978 | J:217958
First Author: Chen H
Year: 2014
Journal: J Physiol
Title: Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse.
Volume: 592
Issue: 3
Pages: 505-21
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Publication
32817622 | J:297077
First Author: Eyster CA
Year: 2020
Journal: PLoS One
Title: Diabetes induced decreases in PKA signaling in cardiomyocytes: The role of insulin.
Volume: 15
Issue: 8
Pages: e0231806
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Publication
29211719 | J:254386
First Author: Hu J
Year: 2017
Journal: Nature
Title: Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
Volume: 552
Issue: 7684
Pages: 248-252
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29231167 | J:254988
   
First Author: Nakano H
Year: 2017
Journal: Elife
Title: Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis.
Volume: 6
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27802520 | J:257138
First Author: Blair NP
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2Akita Diabetic Mice.
Volume: 57
Issue: 14
Pages: 5903-5909
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36001973 | J:328274
First Author: Yang B
Year: 2022
Journal: Cell Rep
Title: Macrophages and neutrophils are necessary for ER stress-induced β cell loss.
Volume: 40
Issue: 8
Pages: 111255
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Publication
15033933 | J:118471
First Author: Zuber C
Year: 2004
Journal: FASEB J
Title: Misfolded proinsulin accumulates in expanded pre-Golgi intermediates and endoplasmic reticulum subdomains in pancreatic beta cells of Akita mice.
Volume: 18
Issue: 7
Pages: 917-9
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Publication
25536533 | J:230273
 
First Author: Gupta I
Year: 2015
Journal: Exp Eye Res
Title: In vivo ZW800-microbead imaging of retinal and choroidal vascular leakage in mice.
Volume: 134
Pages: 155-8
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Publication
30463601 | J:281931
First Author: Elshaer SL
Year: 2018
Journal: Stem Cell Res Ther
Title: Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse.
Volume: 9
Issue: 1
Pages: 322
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Publication
22842467 | J:188036
First Author: Chavali V
Year: 2012
Journal: Biochem Biophys Res Commun
Title: MicroRNA-133a regulates DNA methylation in diabetic cardiomyocytes.
Volume: 425
Issue: 3
Pages: 668-72
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30773020 | J:292481
First Author: Kidokoro K
Year: 2019
Journal: Circulation
Title: Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging.
Volume: 140
Issue: 4
Pages: 303-315
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Publication
36522378 | J:332149
First Author: Juin SK
Year: 2022
Journal: Sci Rep
Title: Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes.
Volume: 12
Issue: 1
Pages: 21707
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Publication
27855634 | J:239407
First Author: Rubin A
Year: 2016
Journal: BMC Genomics
Title: Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq.
Volume: 17
Issue: 1
Pages: 936
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Publication
9039503 | J:40695
First Author: Sasaki H
Year: 1996
Journal: DNA Res
Title: Nucleotide sequence of a 28-kb mouse genomic region comprising the imprinted Igf2 gene.
Volume: 3
Issue: 5
Pages: 331-5
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25912440 | J:316658
First Author: Abdellatif AM
Year: 2015
Journal: Exp Anim
Title: Role of large MAF transcription factors in the mouse endocrine pancreas.
Volume: 64
Issue: 3
Pages: 305-12
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Publication
35113157 | J:324240
First Author: Liu D
Year: 2022
Journal: Diabetes
Title: YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells.
Volume: 71
Issue: 5
Pages: 961-977
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Publication
34462258 | J:324187
First Author: Alam M
Year: 2021
Journal: Diabetes
Title: Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.
Volume: 70
Issue: 11
Pages: 2580-2594
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9144203 | J:40377
First Author: Duvillié B
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Phenotypic alterations in insulin-deficient mutant mice.
Volume: 94
Issue: 10
Pages: 5137-40
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11272179 | J:77595
 
First Author: Leroux L
Year: 2001
Journal: Diabetes
Title: Compensatory responses in mice carrying a null mutation for Ins1 or Ins2.
Volume: 50 Suppl 1
Pages: S150-3
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9384608 | J:45387
First Author: Greally JM
Year: 1998
Journal: Hum Mol Genet
Title: The mouse H19 locus mediates a transition between imprinted and non-imprinted DNA replication patterns.
Volume: 7
Issue: 1
Pages: 91-5
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17855560 | J:125160
First Author: Støy J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Insulin gene mutations as a cause of permanent neonatal diabetes.
Volume: 104
Issue: 38
Pages: 15040-4
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20308425 | J:158805
First Author: Zito E
Year: 2010
Journal: J Cell Biol
Title: ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis.
Volume: 188
Issue: 6
Pages: 821-32
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Publication
23410753 | J:200802
First Author: Kobayashi H
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Ablation of Rnf213 retards progression of diabetes in the Akita mouse.
Volume: 432
Issue: 3
Pages: 519-25
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20724579 | J:169338
First Author: Pendse AA
Year: 2010
Journal: Diabetes
Title: Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction.
Volume: 59
Issue: 11
Pages: 2890-7
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18439911 | J:136249
First Author: Hirosawa M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Ablation of estrogen receptor alpha (ERalpha) prevents upregulation of POMC by leptin and insulin.
Volume: 371
Issue: 2
Pages: 320-3
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30665571 | J:294145
First Author: Wang L
Year: 2019
Journal: Kidney Int
Title: Knockout of TRPC6 promotes insulin resistance and exacerbates glomerular injury in Akita mice.
Volume: 95
Issue: 2
Pages: 321-332
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Publication
33090974 | J:331044
 
First Author: Cai Z
Year: 2021
Journal: J Clin Invest
Title: Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid.
Volume: 131
Issue: 1
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30425286 | J:268145
First Author: Saddala MS
Year: 2018
Journal: Sci Rep
Title: Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina.
Volume: 8
Issue: 1
Pages: 16728
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Publication
25187372 | J:230203
First Author: Huang H
Year: 2015
Journal: Diabetes
Title: Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1α-VEGF pathway inhibition.
Volume: 64
Issue: 1
Pages: 200-12
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Publication
22896043 | J:189948
First Author: Basu R
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Loss of TIMP3 selectively exacerbates diabetic nephropathy.
Volume: 303
Issue: 9
Pages: F1341-52
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Publication
31806622 | J:285320
First Author: Garcia-Vaz E
Year: 2020
Journal: Diabetes
Title: Inhibition of NFAT Signaling Restores Microvascular Endothelial Function in Diabetic Mice.
Volume: 69
Issue: 3
Pages: 424-435
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Publication
33485967 | J:302165
   
First Author: Klyuyeva AV
Year: 2021
Journal: J Biol Chem
Title: Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes.
Pages: 100323
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Publication
30207172 | J:283969
First Author: Vashistha H
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent.
Volume: 315
Issue: 6
Pages: F1833-F1842
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18559662 | J:141775
First Author: Pfister F
Year: 2008
Journal: Diabetes
Title: Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy.
Volume: 57
Issue: 9
Pages: 2495-502
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Publication
31492508 | J:297189
First Author: Zhang D
Year: 2019
Journal: Kidney Int
Title: The caveolin-1 regulated protein follistatin protects against diabetic kidney disease.
Volume: 96
Issue: 5
Pages: 1134-1149
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Publication
24677271 | J:249668
First Author: Bjørklund MM
Year: 2014
Journal: Circ Res
Title: Induction of atherosclerosis in mice and hamsters without germline genetic engineering.
Volume: 114
Issue: 11
Pages: 1684-9
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Publication
21606463 | J:174983
First Author: Zhou C
Year: 2011
Journal: J Lipid Res
Title: Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease.
Volume: 52
Issue: 8
Pages: 1483-93
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11854325 | J:74700
First Author: Oyadomari S
Year: 2002
Journal: J Clin Invest
Title: Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes.
Volume: 109
Issue: 4
Pages: 525-32
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26552047 | J:228069
First Author: Nagasu H
Year: 2016
Journal: Lab Invest
Title: Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice.
Volume: 96
Issue: 1
Pages: 25-36
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27581061 | J:254079
 
First Author: Coleman SK
Year: 2016
Journal: Sci Rep
Title: Myostatin inhibition therapy for insulin-deficient type 1 diabetes.
Volume: 6
Pages: 32495
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Publication
31069235 | J:289563
 
First Author: Kambis TN
Year: 2019
Journal: Front Cardiovasc Med
Title: Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.
Volume: 6
Pages: 45
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Publication
21555558 | J:171899
First Author: Fox R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Volume: 108
Issue: 21
Pages: 8779-84
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Publication
30646747 | J:281960
First Author: Wu S
Year: 2019
Journal: Circulation
Title: Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo.
Volume: 139
Issue: 16
Pages: 1913-1936
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Publication
29074590 | J:269248
First Author: Paquin-Veillette J
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of AT2 Receptor Prevents SHP-1-Induced VEGF Inhibition and Improves Blood Flow Reperfusion in Diabetic Ischemic Hindlimb.
Volume: 37
Issue: 12
Pages: 2291-2300
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Publication
31726870 | J:293617
First Author: Robillard S
Year: 2020
Journal: Diab Vasc Dis Res
Title: Ablation of angiotensin type 2 receptor prevents endothelial nitric oxide synthase glutathionylation and nitration in ischaemic abductor muscle of diabetic mice.
Volume: 17
Issue: 1
Pages: 1479164119883978
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Publication
23649519 | J:208962
First Author: Abudukadier A
Year: 2013
Journal: Diabetes
Title: Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice.
Volume: 62
Issue: 9
Pages: 3033-43
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Publication
31380462 | J:286353
 
First Author: Verma A
Year: 2019
Journal: Mol Ther Methods Clin Dev
Title: Expression of Human ACE2 in Lactobacillus and Beneficial Effects in Diabetic Retinopathy in Mice.
Volume: 14
Pages: 161-170
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Publication
33713581 | J:325388
First Author: Wetzel MD
Year: 2021
Journal: Physiol Rep
Title: Homoarginine ameliorates diabetic nephropathy independent of nitric oxide synthase-3.
Volume: 9
Issue: 5
Pages: e14766
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Publication
21245338 | J:169115
First Author: Wang CH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy.
Volume: 108
Issue: 5
Pages: 2070-5
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Publication
30168649 | J:267337
First Author: Huy H
Year: 2018
Journal: Aging Cell
Title: TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress.
Volume: 17
Issue: 6
Pages: e12836
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Publication
24743240 | J:215198
First Author: Kikawa K
Year: 2014
Journal: PLoS One
Title: Beneficial effect of insulin treatment on islet transplantation outcomes in Akita mice.
Volume: 9
Issue: 4
Pages: e95451
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Publication
22883233 | J:187377
First Author: Lerner AG
Year: 2012
Journal: Cell Metab
Title: IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Volume: 16
Issue: 2
Pages: 250-64
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Publication
21429093 | J:185702
First Author: Jaholkowski P
Year: 2011
Journal: Genes Brain Behav
Title: Increased ethanol intake and preference in cyclin D2 knockout mice.
Volume: 10
Issue: 5
Pages: 551-6
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31091127 | J:281029
First Author: Song P
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration.
Volume: 317
Issue: 1
Pages: F207-F217
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21139688 | J:168105
 
First Author: Kern TS
Year: 2010
Journal: Mol Vis
Title: Validation of structural and functional lesions of diabetic retinopathy in mice.
Volume: 16
Pages: 2121-31
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24966386 | J:212541
First Author: Rudchenko A
Year: 2014
Journal: J Neurosci
Title: Synapses on sympathetic neurons and parasympathetic neurons differ in their vulnerability to diabetes.
Volume: 34
Issue: 26
Pages: 8865-74
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30488085 | J:276214
First Author: Yoshitake S
Year: 2019
Journal: Diabetologia
Title: Anti-fumarase antibody promotes the dropout of photoreceptor inner and outer segments in diabetic macular oedema.
Volume: 62
Issue: 3
Pages: 504-516
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Publication
30065034 | J:265164
First Author: Gurley SB
Year: 2018
Journal: Diabetes
Title: Inflammation and Immunity Pathways Regulate Genetic Susceptibility to Diabetic Nephropathy.
Volume: 67
Issue: 10
Pages: 2096-2106
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15731364 | J:99270
First Author: Lu YC
Year: 2005
Journal: Endocrinology
Title: Release of transgenic human insulin from gastric g cells: a novel approach for the amelioration of diabetes.
Volume: 146
Issue: 6
Pages: 2610-9
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Publication
25652452 | J:224012
First Author: Natarajan M
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Inhibitor-κB kinase attenuates Hsp90-dependent endothelial nitric oxide synthase function in vascular endothelial cells.
Volume: 308
Issue: 8
Pages: C673-83
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Publication
20501666 | J:161074
First Author: Wende AR
Year: 2010
Journal: Endocrinology
Title: Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice.
Volume: 151
Issue: 8
Pages: 3536-42
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20479236 | J:161075
First Author: Kakoki M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
Volume: 107
Issue: 22
Pages: 10190-5
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22297234 | J:181355
First Author: Grupillo M
Year: 2012
Journal: Cell Immunol
Title: Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells.
Volume: 273
Issue: 2
Pages: 115-23
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Publication
35940125 | J:328246
 
First Author: Rousseau M
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Reduction of DUSP4 contributes to podocytes oxidative stress, insulin resistance and diabetic nephropathy.
Volume: 624
Pages: 127-133
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Publication
33831261 | J:325387
First Author: Leanza G
Year: 2021
Journal: J Bone Miner Res
Title: Gain-of-Function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes.
Volume: 36
Issue: 7
Pages: 1403-1415
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Publication
21677281 | J:186814
First Author: Hodish I
Year: 2011
Journal: Diabetes
Title: In vivo misfolding of proinsulin below the threshold of frank diabetes.
Volume: 60
Issue: 8
Pages: 2092-101
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Publication
21926276 | J:189484
First Author: Morris SM Jr
Year: 2011
Journal: Diabetes
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