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Search results 1 to 100 out of 1342 for Pdx1

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Type Details Score
Publication
26657766 | J:229014
First Author: Marty-Santos L
Year: 2016
Journal: Development
Title: Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.
Volume: 143
Issue: 1
Pages: 101-12
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Publication
21852533 | J:174673
First Author: Yang YP
Year: 2011
Journal: Genes Dev
Title: Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.
Volume: 25
Issue: 16
Pages: 1680-5
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Publication
28017717 | J:241963
First Author: Yamamoto Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Preserving expression of Pdx1 improves β-cell failure in diabetic mice.
Volume: 483
Issue: 1
Pages: 418-424
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Publication
28087712 | J:238701
First Author: Roy N
Year: 2016
Journal: Genes Dev
Title: PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Volume: 30
Issue: 24
Pages: 2669-2683
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Publication
26887806 | J:250031
 
First Author: Kodama S
Year: 2016
Journal: Sci Rep
Title: Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice.
Volume: 6
Pages: 21211
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Publication
12145169 | J:78086
First Author: Lee CS
Year: 2002
Journal: Diabetes
Title: Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.
Volume: 51
Issue: 8
Pages: 2546-51
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Publication
11994408 | J:76408
First Author: Kushner JA
Year: 2002
Journal: J Clin Invest
Title: Pdx1 restores beta cell function in Irs2 knockout mice.
Volume: 109
Issue: 9
Pages: 1193-201
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Publication
28580283 | J:301635
First Author: Bastidas-Ponce A
Year: 2017
Journal: Mol Metab
Title: Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells.
Volume: 6
Issue: 6
Pages: 524-534
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Publication
20558340 | J:161931
First Author: Galbo T
Year: 2010
Journal: Eur J Histochem
Title: Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels.
Volume: 54
Issue: 2
Pages: e19
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Publication
19855005 | J:154661
First Author: Sachdeva MM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.
Volume: 106
Issue: 45
Pages: 19090-5
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Publication
29351489 | J:262148
First Author: Kropp PA
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability.
Volume: 314
Issue: 4
Pages: E308-E321
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Publication
19656489 | J:151308
First Author: Gauthier BR
Year: 2009
Journal: Cell Metab
Title: PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
Volume: 10
Issue: 2
Pages: 110-8
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Publication
17403901 | J:122333
First Author: Wiebe PO
Year: 2007
Journal: Mol Cell Biol
Title: Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.
Volume: 27
Issue: 11
Pages: 4093-104
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Publication
24658302 | J:229796
First Author: Ren D
Year: 2014
Journal: Diabetes
Title: Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
Volume: 63
Issue: 8
Pages: 2744-50
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Publication
24506867 | J:210652
First Author: Gao T
Year: 2014
Journal: Cell Metab
Title: Pdx1 maintains β cell identity and function by repressing an α cell program.
Volume: 19
Issue: 2
Pages: 259-71
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Publication
27292642 | J:238301
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
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Publication
16126192 | J:103522
First Author: Hale MA
Year: 2005
Journal: Dev Biol
Title: The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas.
Volume: 286
Issue: 1
Pages: 225-37
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Publication
17158802 | J:118281
First Author: Johnson JD
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome.
Volume: 103
Issue: 51
Pages: 19575-80
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Publication
24029239 | J:204080
First Author: Nishimura W
Year: 2013
Journal: Endocrinology
Title: Quantitative assessment of Pdx1 promoter activity in vivo using a secreted luciferase reporter system.
Volume: 154
Issue: 11
Pages: 4388-95
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Publication
22135308 | J:183312
First Author: Chen C
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice.
Volume: 302
Issue: 4
Pages: G407-19
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Publication
12488434 | J:80826
First Author: Kitamura T
Year: 2002
Journal: J Clin Invest
Title: The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.
Volume: 110
Issue: 12
Pages: 1839-47
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Publication
25801033 | J:316508
First Author: McKenna B
Year: 2015
Journal: Cell Rep
Title: Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells.
Volume: 10
Issue: 12
Pages: 2032-42
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Publication
15677506 | J:105152
First Author: Li Y
Year: 2005
Journal: Diabetes
Title: beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.
Volume: 54
Issue: 2
Pages: 482-91
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Publication
19654319 | J:155712
First Author: Fujimoto K
Year: 2009
Journal: J Biol Chem
Title: Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation.
Volume: 284
Issue: 40
Pages: 27664-73
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26085571 | J:247099
First Author: Soleimanpour SA
Year: 2015
Journal: Diabetes
Title: Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells.
Volume: 64
Issue: 10
Pages: 3475-84
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Publication
29723041 | J:272409
First Author: Ikeguchi E
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Transcriptional factor Pdx1 is involved in age-related GIP hypersecretion in mice.
Volume: 315
Issue: 2
Pages: G272-G282
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12869553 | J:128796
First Author: Suzuki R
Year: 2003
Journal: J Biol Chem
Title: Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.
Volume: 278
Issue: 44
Pages: 43691-8
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Publication
25040025 | J:215612
First Author: Fernández-Pérez A
Year: 2014
Journal: Biochem J
Title: Pdx1 and USF transcription factors co-ordinately regulate Alx3 gene expression in pancreatic β-cells.
Volume: 463
Issue: 2
Pages: 287-96
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Publication
17056599 | J:117676
First Author: Deramaudt TB
Year: 2006
Journal: J Biol Chem
Title: The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter.
Volume: 281
Issue: 50
Pages: 38385-95
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Publication
25251389 | J:218424
First Author: Templin AT
Year: 2014
Journal: Mol Endocrinol
Title: Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response.
Volume: 28
Issue: 11
Pages: 1820-30
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Publication
23775765 | J:208954
First Author: Guo L
Year: 2013
Journal: Diabetes
Title: PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.
Volume: 62
Issue: 10
Pages: 3459-68
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22771330 | J:186237
First Author: Chen C
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Intestinal Pdx1 mediates nutrient metabolism gene networks and maternal expression is essential for perinatal growth in mice.
Volume: 424
Issue: 3
Pages: 549-53
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Publication
31240701 | J:280914
First Author: Horiguchi M
Year: 2019
Journal: FEBS Lett
Title: Senescence caused by inactivation of the homeodomain transcription factor Pdx1 in adult pancreatic acinar cells in mice.
Volume: 593
Issue: 16
Pages: 2226-2234
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20811152 | J:165268
First Author: Claiborn KC
Year: 2010
Journal: J Clin Invest
Title: Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice.
Volume: 120
Issue: 10
Pages: 3713-21
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Publication
21042537 | J:166709
First Author: Mazur PK
Year: 2010
Journal: PLoS One
Title: Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
Volume: 5
Issue: 10
Pages: e13578
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Publication
19141476 | J:143476
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
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19487809 | J:152582
First Author: Oliver-Krasinski JM
Year: 2009
Journal: J Clin Invest
Title: The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.
Volume: 119
Issue: 7
Pages: 1888-98
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27993987 | J:238418
First Author: Yang YP
Year: 2017
Journal: Development
Title: The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Volume: 144
Issue: 2
Pages: 248-257
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29910119 | J:264987
     
First Author: Malenczyk K
Year: 2018
Journal: Mol Metab
Title: Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification.
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Publication
27406855 | J:253778
 
First Author: Guo C
Year: 2016
Journal: Sci Rep
Title: Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model.
Volume: 6
Pages: 29396
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25713082 | J:338772
First Author: Maganti AV
Year: 2015
Journal: J Biol Chem
Title: Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.
Volume: 290
Issue: 15
Pages: 9812-22
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16148004 | J:102900
First Author: Iguchi H
Year: 2005
Journal: J Biol Chem
Title: SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Volume: 280
Issue: 45
Pages: 37669-80
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26440894 | J:273053
First Author: Shih HP
Year: 2015
Journal: Cell Rep
Title: A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells.
Volume: 13
Issue: 2
Pages: 326-36
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Publication
16123346 | J:101742
First Author: Holland AM
Year: 2005
Journal: Diabetes
Title: Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas.
Volume: 54
Issue: 9
Pages: 2586-95
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Publication
16794995 | J:110137
First Author: Holland AM
Year: 2006
Journal: Genesis
Title: A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.
Volume: 44
Issue: 6
Pages: 304-7
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16418487 | J:104617
First Author: Fujitani Y
Year: 2006
Journal: Genes Dev
Title: Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
Volume: 20
Issue: 2
Pages: 253-66
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28705881 | J:245178
First Author: Spaeth JM
Year: 2017
Journal: Diabetes
Title: Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
Volume: 66
Issue: 11
Pages: 2830-2839
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16962573 | J:119565
First Author: Boyer DF
Year: 2006
Journal: Dev Biol
Title: Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.
Volume: 298
Issue: 2
Pages: 616-31
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19808654 | J:155907
First Author: Chen C
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells.
Volume: 297
Issue: 6
Pages: G1126-37
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18347078 | J:137140
First Author: Hald J
Year: 2008
Journal: J Histochem Cytochem
Title: Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development.
Volume: 56
Issue: 6
Pages: 587-95
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11784003 | J:72023
First Author: Gannon M
Year: 2001
Journal: Dev Biol
Title: Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.
Volume: 238
Issue: 1
Pages: 185-201
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31682591 | J:295434
First Author: Trojanowski BM
Year: 2020
Journal: J Endocrinol
Title: Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.
Volume: 244
Issue: 2
Pages: 323-337
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11973276 | J:76095
First Author: Gu G
Year: 2002
Journal: Development
Title: Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Volume: 129
Issue: 10
Pages: 2447-57
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32165492 | J:291485
 
First Author: Baumann D
Year: 2020
Journal: Development
Title: Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.
Volume: 147
Issue: 7
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34735515 | J:312867
First Author: Walcheck MT
Year: 2021
Journal: PLoS One
Title: Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice.
Volume: 16
Issue: 11
Pages: e0259245
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36623733 | J:337682
First Author: Wong A
Year: 2023
Journal: J Biol Chem
Title: Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion.
Volume: 299
Issue: 2
Pages: 102878
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9637677 | J:48516
First Author: Ahlgren U
Year: 1998
Journal: Genes Dev
Title: beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes.
Volume: 12
Issue: 12
Pages: 1763-8
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28922976 | J:257633
First Author: Jiang FX
Year: 2017
Journal: Stem Cells Dev
Title: Transient Impairment of Islet Architectural Development in Pancreas-Specific Bmpr1a-Deleted Prenatal Mice Involves Reduced Expression of E-Cadherin.
Volume: 26
Issue: 23
Pages: 1706-1714
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20802254 | J:169727
First Author: Wicksteed B
Year: 2010
Journal: Diabetes
Title: Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Volume: 59
Issue: 12
Pages: 3090-8
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19619492 | J:151981
First Author: Spence JR
Year: 2009
Journal: Dev Cell
Title: Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.
Volume: 17
Issue: 1
Pages: 62-74
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16611688 | J:108521
First Author: Heiser PW
Year: 2006
Journal: Development
Title: Stabilization of beta-catenin impacts pancreas growth.
Volume: 133
Issue: 10
Pages: 2023-32
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27137932 | J:340178
First Author: Sun J
Year: 2016
Journal: J Biol Chem
Title: Pancreatic β-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak.
Volume: 291
Issue: 26
Pages: 13529-34
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32547704 | J:311561
First Author: Asai A
Year: 2020
Journal: Oncotarget
Title: Hereditary pancreatitis model by blastocyst complementation in mouse.
Volume: 11
Issue: 22
Pages: 2061-2073
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19805515 | J:154990
First Author: Kang HS
Year: 2009
Journal: Mol Cell Biol
Title: Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.
Volume: 29
Issue: 24
Pages: 6366-79
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20950489 | J:203897
 
First Author: Honig G
Year: 2010
Journal: J Biomed Sci
Title: Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line.
Volume: 17
Pages: 82
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19651901 | J:153774
First Author: Ueda T
Year: 2009
Journal: Mol Cell Biol
Title: The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretion.
Volume: 29
Issue: 19
Pages: 5264-76
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19208834 | J:146440
First Author: Shen HC
Year: 2009
Journal: Cancer Res
Title: Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
Volume: 69
Issue: 5
Pages: 1858-66
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15888377 | J:99302
First Author: Rosanas-Urgell A
Year: 2005
Journal: Mol Cell Endocrinol
Title: Pdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic islets.
Volume: 237
Issue: 1-2
Pages: 59-66
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30026551 | J:266241
First Author: La HM
Year: 2018
Journal: Nat Commun
Title: Identification of dynamic undifferentiated cell states within the male germline.
Volume: 9
Issue: 1
Pages: 2819
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23093780 | J:194010
First Author: Iglesias J
Year: 2012
Journal: J Clin Invest
Title: PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Volume: 122
Issue: 11
Pages: 4105-17
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26516699 | J:316707
First Author: Rachagani S
Year: 2015
Journal: Oncotarget
Title: Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered KrasG12D;Pdx1-Cre mouse (KC) model.
Volume: 6
Issue: 37
Pages: 40295-309
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34302028 | J:308632
First Author: Liot S
Year: 2021
Journal: Sci Rep
Title: Development of thymic tumor in [LSL:KrasG12D; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis.
Volume: 11
Issue: 1
Pages: 15075
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21913313 | J:187872
First Author: Potter LA
Year: 2012
Journal: Genesis
Title: A recombinase-mediated cassette exchange-derived cyan fluorescent protein reporter allele for Pdx1.
Volume: 50
Issue: 4
Pages: 384-92
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12221286 | J:79206
First Author: Holland AM
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Experimental control of pancreatic development and maintenance.
Volume: 99
Issue: 19
Pages: 12236-41
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10579983 | J:59869
First Author: Song SY
Year: 1999
Journal: Gastroenterology
Title: Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha.
Volume: 117
Issue: 6
Pages: 1416-26
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15585742 | J:114151
First Author: Micallef SJ
Year: 2005
Journal: Diabetes
Title: Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells.
Volume: 54
Issue: 2
Pages: 301-5
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12697734 | J:82969
First Author: Johnson JD
Year: 2003
Journal: J Clin Invest
Title: Increased islet apoptosis in Pdx1+/- mice.
Volume: 111
Issue: 8
Pages: 1147-60
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14704343 | J:210927
First Author: Liberzon A
Year: 2004
Journal: Nucleic Acids Res
Title: Role of intrinsic DNA binding specificity in defining target genes of the mammalian transcription factor PDX1.
Volume: 32
Issue: 1
Pages: 54-64
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34462257 | J:331771
First Author: Mohan R
Year: 2021
Journal: Diabetes
Title: OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1.
Volume: 70
Issue: 11
Pages: 2608-2625
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18718916 | J:143390
First Author: Gupta D
Year: 2008
Journal: J Biol Chem
Title: In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter.
Volume: 283
Issue: 47
Pages: 32462-70
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20978346 | J:166916
First Author: Fujimoto K
Year: 2010
Journal: J Clin Invest
Title: Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes.
Volume: 120
Issue: 11
Pages: 4031-9
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21540283 | J:174900
First Author: Khoo C
Year: 2011
Journal: Endocrinology
Title: Endoplasmic reticulum oxidoreductin-1-like β (ERO1lβ) regulates susceptibility to endoplasmic reticulum stress and is induced by insulin flux in β-cells.
Volume: 152
Issue: 7
Pages: 2599-608
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30333365 | J:295664
First Author: Kohara K
Year: 2019
Journal: Endocr J
Title: Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
Volume: 66
Issue: 1
Pages: 43-50
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Publication
23946427 | J:200985
First Author: Cai EP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.
Volume: 110
Issue: 36
Pages: 14723-8
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Publication
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