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Search results 2501 to 2600 out of 2901 for Pdx1

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Type Details Score
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdx1/Pdx1<+>
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafa/Mafa Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafa/Mafa Mafb/Mafb Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmpr1a/Bmpr1a Tg(Pdx1-cre)1Herr/?
Background: B6.Cg-Bmpr1a Tg(Pdx1-cre)1Herr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk3/Stk3 Stk4/Stk4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk3/Stk3<+> Stk4/Stk4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sirt1/Sirt1 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm6a/Kdm6a Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6J * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-flpo)#Koli/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Onecut1/Onecut1<+> Pdx1/Pdx1<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lats1/Lats1 Lats2/Lats2 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6Brd * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pdx1-cre)6Tuv/? Tle3/Tle3 Tle4/Tle4
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm6b/Kdm6b Neurog3/Neurog3<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
18421434 | J:137920
First Author: Mehrabian M
Year: 2008
Journal: Diabetologia
Title: Identification of ALOX5 as a gene regulating adiposity and pancreatic function.
Volume: 51
Issue: 6
Pages: 978-88
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Publication
26546129 | J:230840
First Author: Jurczyk A
Year: 2016
Journal: FASEB J
Title: Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.
Volume: 30
Issue: 2
Pages: 983-93
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Publication
23251699 | J:195661
First Author: van der Meulen T
Year: 2012
Journal: PLoS One
Title: Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells.
Volume: 7
Issue: 12
Pages: e52181
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Publication
28377501 | J:243672
First Author: Mitchell RK
Year: 2017
Journal: J Biol Chem
Title: The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.
Volume: 292
Issue: 21
Pages: 8892-8906
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Publication
28642969 | J:252014
First Author: Ida S
Year: 2017
Journal: Diabetologia
Title: Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.
Volume: 60
Issue: 9
Pages: 1761-1769
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Publication
23531612 | J:198216
First Author: Crivello M
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors.
Volume: 304
Issue: 10
Pages: E1064-76
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Publication
24989997 | J:218130
First Author: Chen YC
Year: 2014
Journal: Diabetologia
Title: Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes.
Volume: 57
Issue: 10
Pages: 2066-75
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Publication
22374815 | J:188469
First Author: Johnson CL
Year: 2012
Journal: J Pathol
Title: Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1.
Volume: 228
Issue: 3
Pages: 351-65
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Publication
12493745 | J:82924
First Author: Terauchi Y
Year: 2003
Journal: J Biol Chem
Title: Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.
Volume: 278
Issue: 16
Pages: 14284-90
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Publication
22230751 | J:182707
First Author: Miki R
Year: 2012
Journal: Mech Dev
Title: Fate maps of ventral and dorsal pancreatic progenitor cells in early somite stage mouse embryos.
Volume: 128
Issue: 11-12
Pages: 597-609
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Publication
1825611 | -
First Author: Russell GC
Year: 1991
Journal: Biochim Biophys Acta
Title: Sequence similarities within the family of dihydrolipoamide acyltransferases and discovery of a previously unidentified fungal enzyme.
Volume: 1076
Issue: 2
Pages: 225-32
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Publication
20865670 | -
First Author: Kang HS
Year: 2010
Journal: Histol Histopathol
Title: Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
Volume: 25
Issue: 11
Pages: 1481-96
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Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
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Publication
22565310 | J:188293
First Author: Hamidi T
Year: 2012
Journal: J Clin Invest
Title: Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
Volume: 122
Issue: 6
Pages: 2092-103
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Publication
24949970 | J:214528
First Author: Soleimanpour SA
Year: 2014
Journal: Cell
Title: The diabetes susceptibility gene Clec16a regulates mitophagy.
Volume: 157
Issue: 7
Pages: 1577-90
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Publication
21051638 | J:218666
First Author: Kraman M
Year: 2010
Journal: Science
Title: Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.
Volume: 330
Issue: 6005
Pages: 827-30
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Publication
20627934 | J:169626
First Author: Artner I
Year: 2010
Journal: Diabetes
Title: MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Volume: 59
Issue: 10
Pages: 2530-9
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Publication
27813676 | J:245502
First Author: Yang Y
Year: 2017
Journal: Endocrinology
Title: Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.
Volume: 158
Issue: 1
Pages: 9-20
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Publication
27049944 | J:264967
First Author: Seifert L
Year: 2016
Journal: Nature
Title: The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression.
Volume: 532
Issue: 7598
Pages: 245-9
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Publication
34294685 | J:337676
First Author: Perez-Frances M
Year: 2021
Journal: Nat Commun
Title: Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production.
Volume: 12
Issue: 1
Pages: 4458
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Publication
25043018 | J:217116
First Author: Walz S
Year: 2014
Journal: Nature
Title: Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Volume: 511
Issue: 7510
Pages: 483-7
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Publication
31187215 | J:282554
First Author: Mandelbaum AD
Year: 2019
Journal: Diabetologia
Title: miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice.
Volume: 62
Issue: 9
Pages: 1653-1666
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Publication
22611036 | J:187012
First Author: Singh M
Year: 2012
Journal: J Pathol
Title: Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Volume: 227
Issue: 4
Pages: 417-30
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Publication
22945649 | J:199980
First Author: Norris AM
Year: 2013
Journal: Oncogene
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Volume: 32
Issue: 33
Pages: 3867-76
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Publication
32591410 | J:296309
First Author: Yamauchi Y
Year: 2020
Journal: Cancer Res
Title: Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors.
Volume: 80
Issue: 17
Pages: 3620-3630
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Publication
24150605 | J:209019
First Author: Chen Z
Year: 2014
Journal: Diabetes
Title: SH2B1 in β-cells regulates glucose metabolism by promoting β-cell survival and islet expansion.
Volume: 63
Issue: 2
Pages: 585-95
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Publication
31197017 | J:278164
First Author: Elyada E
Year: 2019
Journal: Cancer Discov
Title: Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Volume: 9
Issue: 8
Pages: 1102-1123
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Publication
30303066 | J:269819
   
First Author: Ceasrine AM
Year: 2018
Journal: Elife
Title: Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature.
Volume: 7
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Publication
23949579 | J:203844
First Author: Jiao Y
Year: 2013
Journal: Diabetologia
Title: CISH has no non-redundant functions in glucose homeostasis or beta cell proliferation during pregnancy in mice.
Volume: 56
Issue: 11
Pages: 2435-45
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Publication
22784710 | J:208743
First Author: Hill R
Year: 2012
Journal: Mol Cancer Ther
Title: Cell intrinsic role of COX-2 in pancreatic cancer development.
Volume: 11
Issue: 10
Pages: 2127-37
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Publication
29533787 | J:258620
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
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Publication
34388391 | J:316758
First Author: Koikawa K
Year: 2021
Journal: Cell
Title: Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Volume: 184
Issue: 18
Pages: 4753-4771.e27
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Publication
37216093 | J:338920
First Author: Fadzeyeva E
Year: 2023
Journal: iScience
Title: Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
Volume: 26
Issue: 5
Pages: 106748
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Publication
23284900 | J:195622
First Author: Avila JL
Year: 2012
Journal: PLoS One
Title: Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 12
Pages: e52133
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Publication
20616010 | J:162410
First Author: Wong WP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis.
Volume: 107
Issue: 29
Pages: 13057-62
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Publication
26669866 | J:237653
First Author: Kaistha BP
Year: 2016
Journal: Cancer Res
Title: PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways.
Volume: 76
Issue: 1
Pages: 96-107
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Publication
19808022 | J:153660
First Author: Granot Z
Year: 2009
Journal: Cell Metab
Title: LKB1 regulates pancreatic beta cell size, polarity, and function.
Volume: 10
Issue: 4
Pages: 296-308
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Publication
23204224 | J:194376
First Author: Shakya R
Year: 2013
Journal: Cancer Res
Title: Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.
Volume: 73
Issue: 2
Pages: 885-96
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Publication
26575024 | J:280480
First Author: Mace TA
Year: 2015
Journal: Oncotarget
Title: Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Volume: 6
Issue: 42
Pages: 44509-22
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Publication
31877165 | J:283370
First Author: Park D
Year: 2019
Journal: PLoS One
Title: Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Volume: 14
Issue: 12
Pages: e0226714
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Publication
19665969 | J:153905
First Author: Collombat P
Year: 2009
Journal: Cell
Title: The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells.
Volume: 138
Issue: 3
Pages: 449-62
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Publication
23788637 | J:203472
First Author: Gupta D
Year: 2013
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor γ (PPARγ) and its target genes are downstream effectors of FoxO1 protein in islet β-cells: mechanism of β-cell compensation and failure.
Volume: 288
Issue: 35
Pages: 25440-9
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Publication
28294115 | J:244261
 
First Author: Gundry C
Year: 2017
Journal: Nat Commun
Title: Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Volume: 8
Pages: 14646
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Publication
17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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Publication
16585505 | J:108298
First Author: Bardeesy N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Volume: 103
Issue: 15
Pages: 5947-52
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Publication
19147554 | J:143713
First Author: Seeley ES
Year: 2009
Journal: Cancer Res
Title: Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia.
Volume: 69
Issue: 2
Pages: 422-30
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Publication
22140463 | J:181133
First Author: Carrière C
Year: 2011
Journal: PLoS One
Title: Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
Volume: 6
Issue: 11
Pages: e27725
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Publication
33323382 | J:303990
First Author: Kon N
Year: 2021
Journal: Cancer Res
Title: Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
Volume: 81
Issue: 4
Pages: 935-944
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Publication
26512112 | J:227471
First Author: Antonucci L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress.
Volume: 112
Issue: 45
Pages: E6166-74
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Publication
23563314 | J:201459
First Author: Li N
Year: 2013
Journal: J Clin Invest
Title: Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.
Volume: 123
Issue: 5
Pages: 2231-43
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Publication
27697926 | J:306995
First Author: Kunii M
Year: 2016
Journal: J Cell Biol
Title: Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells.
Volume: 215
Issue: 1
Pages: 121-138
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Publication
30355799 | J:266568
 
First Author: Zhou L
Year: 2018
Journal: Sci Transl Med
Title: Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
Volume: 10
Issue: 464
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Publication
31414143 | J:280275
First Author: Hutch CR
Year: 2019
Journal: Diabetologia
Title: The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice.
Volume: 62
Issue: 10
Pages: 1928-1937
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Publication
36652401 | J:335182
First Author: Arble DM
Year: 2023
Journal: Am J Physiol Endocrinol Metab
Title: The role of preproglucagon peptides in regulating β-cell morphology and responses to streptozotocin-induced diabetes.
Volume: 324
Issue: 3
Pages: E217-E225
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Publication
27216178 | J:232779
First Author: Schultz MJ
Year: 2016
Journal: Cancer Res
Title: The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Volume: 76
Issue: 13
Pages: 3978-88
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Publication
22113502 | J:198619
First Author: Qiu W
Year: 2011
Journal: Oncotarget
Title: Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Volume: 2
Issue: 11
Pages: 862-73
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Publication
19246386 | J:146777
First Author: Tian H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
Volume: 106
Issue: 11
Pages: 4254-9
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Publication
22052106 | J:320501
First Author: DiNorcia J
Year: 2012
Journal: J Gastrointest Surg
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Volume: 16
Issue: 1
Pages: 104-12; discussion 112
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Publication
18725219 | J:142261
First Author: Heiser PW
Year: 2008
Journal: Gastroenterology
Title: Stabilization of beta-catenin induces pancreas tumor formation.
Volume: 135
Issue: 4
Pages: 1288-300
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Publication
26479921 | J:228885
First Author: Alam MS
Year: 2015
Journal: Nat Med
Title: Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Volume: 21
Issue: 11
Pages: 1337-43
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Publication
23034633 | J:189073
First Author: Bénazet JD
Year: 2012
Journal: Development
Title: Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds.
Volume: 139
Issue: 22
Pages: 4250-60
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Publication
24784840 | J:212549
First Author: Park JW
Year: 2014
Journal: Mol Cancer Res
Title: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.
Volume: 12
Issue: 8
Pages: 1088-99
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Publication
33127675 | J:313903
 
First Author: Rossi Sebastiano M
Year: 2020
Journal: Sci Adv
Title: ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression.
Volume: 6
Issue: 44
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Publication
18615728 | J:138548
First Author: An W
Year: 2008
Journal: Genesis
Title: Conditional activation of a single-copy L1 transgene in mice by Cre.
Volume: 46
Issue: 7
Pages: 373-83
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Publication
35472764 | J:326794
First Author: Georgiadou E
Year: 2022
Journal: Diabetes
Title: Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Volume: 71
Issue: 7
Pages: 1472-1489
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Publication
22265420 | J:181291
First Author: Rhim AD
Year: 2012
Journal: Cell
Title: EMT and dissemination precede pancreatic tumor formation.
Volume: 148
Issue: 1-2
Pages: 349-61
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Publication
26438692 | J:226536
First Author: Gopinathan A
Year: 2015
Journal: Dis Model Mech
Title: GEMMs as preclinical models for testing pancreatic cancer therapies.
Volume: 8
Issue: 10
Pages: 1185-200
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Publication
21589862 | J:172643
First Author: Kelly-Spratt KS
Year: 2011
Journal: PLoS One
Title: Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Volume: 6
Issue: 5
Pages: e19721
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Publication
32554750 | J:296297
First Author: Zhao Y
Year: 2020
Journal: Cancer Res
Title: Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Volume: 80
Issue: 16
Pages: 3359-3371
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