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Search results 1 to 100 out of 239 for Mfn2

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Category: Publication
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Type Details Score
Publication
28348166 | J:243358
First Author: Boutant M
Year: 2017
Journal: EMBO J
Title: Mfn2 is critical for brown adipose tissue thermogenic function.
Volume: 36
Issue: 11
Pages: 1543-1558
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Publication
25416777 | J:338764
First Author: Wang W
Year: 2015
Journal: J Biol Chem
Title: MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons.
Volume: 290
Issue: 1
Pages: 168-82
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Publication
12527753 | J:81438
First Author: Chen H
Year: 2003
Journal: J Cell Biol
Title: Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Volume: 160
Issue: 2
Pages: 189-200
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Publication
32330448 | J:305615
First Author: Chen W
Year: 2020
Journal: Stem Cell Reports
Title: MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation.
Volume: 14
Issue: 5
Pages: 803-817
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Publication
31947766 | J:301137
 
First Author: Han S
Year: 2020
Journal: Cells
Title: Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death.
Volume: 9
Issue: 1
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Publication
31281507 | J:295427
First Author: Hu L
Year: 2019
Journal: Theranostics
Title: Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Volume: 9
Issue: 13
Pages: 3687-3706
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Publication
37633049 | J:341116
 
First Author: Zhang S
Year: 2023
Journal: Redox Biol
Title: LRRK2 aggravates kidney injury through promoting MFN2 degradation and abnormal mitochondrial integrity.
Volume: 66
Pages: 102860
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Publication
23921556 | J:200066
First Author: Muñoz JP
Year: 2013
Journal: EMBO J
Title: Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Volume: 32
Issue: 17
Pages: 2348-61
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Publication
26210454 | J:232518
First Author: Kim HJ
Year: 2015
Journal: Biochem Biophys Res Commun
Title: HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation.
Volume: 464
Issue: 4
Pages: 1235-40
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Publication
34948301 | J:317736
 
First Author: Miao J
Year: 2021
Journal: Int J Mol Sci
Title: MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice.
Volume: 22
Issue: 24
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Publication
17296794 | J:119702
First Author: Detmer SA
Year: 2007
Journal: J Cell Biol
Title: Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations.
Volume: 176
Issue: 4
Pages: 405-14
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Publication
22509026 | J:183915
First Author: Li J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression.
Volume: 109
Issue: 18
Pages: 6975-80
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Publication
29391029 | J:301893
First Author: Jiang S
Year: 2018
Journal: Mol Neurodegener
Title: Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.
Volume: 13
Issue: 1
Pages: 5
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Publication
28539390 | J:243572
First Author: Mahdaviani K
Year: 2017
Journal: EMBO Rep
Title: Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.
Volume: 18
Issue: 7
Pages: 1123-1138
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Publication
35493072 | J:324164
 
First Author: Wang T
Year: 2022
Journal: Front Cell Dev Biol
Title: MFN2 Deficiency Impairs Mitochondrial Functions and PPAR Pathway During Spermatogenesis and Meiosis in Mice.
Volume: 10
Pages: 862506
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Publication
27334614 | J:235066
First Author: Sebastián D
Year: 2016
Journal: EMBO J
Title: Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway.
Volume: 35
Issue: 15
Pages: 1677-93
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Publication
29981809 | J:264243
 
First Author: Lee YS
Year: 2018
Journal: Cancer Lett
Title: Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination.
Volume: 433
Pages: 156-164
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Publication
22859504 | J:188347
First Author: Pham AH
Year: 2012
Journal: Hum Mol Genet
Title: Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit.
Volume: 21
Issue: 22
Pages: 4817-26
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Publication
27228353 | J:332038
First Author: Hall AR
Year: 2016
Journal: Cell Death Dis
Title: Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.
Volume: 7
Issue: 5
Pages: e2238
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Publication
33674260 | J:305430
 
First Author: Wang X
Year: 2021
Journal: Development
Title: MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Volume: 148
Issue: 7
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Publication
35472764 | J:326794
First Author: Georgiadou E
Year: 2022
Journal: Diabetes
Title: Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Volume: 71
Issue: 7
Pages: 1472-1489
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Publication
24876927 | J:215337
 
First Author: Vadnais ML
Year: 2014
Journal: Cilia
Title: Mitochondrial fusion protein MFN2 interacts with the mitostatin-related protein MNS1 required for mouse sperm flagellar structure and function.
Volume: 3
Pages: 5
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Publication
27775718 | J:242995
First Author: Franco A
Year: 2016
Journal: Nature
Title: Correcting mitochondrial fusion by manipulating mitofusin conformations.
Volume: 540
Issue: 7631
Pages: 74-79
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Publication
33074106 | J:298900
   
First Author: Franco A
Year: 2020
Journal: Elife
Title: Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
Volume: 9
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27907123 | J:251584
First Author: Bannerman P
Year: 2016
Journal: PLoS One
Title: Mice Hemizygous for a Pathogenic Mitofusin-2 Allele Exhibit Hind Limb/Foot Gait Deficits and Phenotypic Perturbations in Nerve and Muscle.
Volume: 11
Issue: 12
Pages: e0167573
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21285398 | J:172776
First Author: Guillet V
Year: 2011
Journal: FASEB J
Title: Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.
Volume: 25
Issue: 5
Pages: 1618-27
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Publication
31204316 | J:314841
First Author: Zhang M
Year: 2019
Journal: Aging (Albany NY)
Title: Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging.
Volume: 11
Issue: 12
Pages: 3919-3938
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Publication
36125902 | J:332020
 
First Author: Wang X
Year: 2022
Journal: J Clin Invest
Title: A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle.
Volume: 132
Issue: 23
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Publication
29367651 | J:259679
First Author: Zhao J
Year: 2018
Journal: Sci Rep
Title: Embryonic Surface Ectoderm-specific Mitofusin 2 Conditional Knockout Induces Congenital Cataracts in Mice.
Volume: 8
Issue: 1
Pages: 1522
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Publication
25688136 | J:302844
First Author: Mourier A
Year: 2015
Journal: J Cell Biol
Title: Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.
Volume: 208
Issue: 4
Pages: 429-42
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Publication
37440411 | J:338353
First Author: Ghosal S
Year: 2023
Journal: Cell Rep
Title: Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function.
Volume: 42
Issue: 7
Pages: 112776
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Publication
22427360 | J:182659
First Author: Sebastián D
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Volume: 109
Issue: 14
Pages: 5523-8
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Publication
33980844 | J:339598
First Author: Kim YM
Year: 2021
Journal: Nat Commun
Title: Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling.
Volume: 12
Issue: 1
Pages: 2736
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Publication
30865877 | J:280130
First Author: Mancini G
Year: 2019
Journal: Cell Rep
Title: Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight.
Volume: 26
Issue: 11
Pages: 2849-2858.e4
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Publication
31051106 | J:337405
First Author: Hernández-Alvarez MI
Year: 2019
Journal: Cell
Title: Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.
Volume: 177
Issue: 4
Pages: 881-895.e17
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Publication
37347868 | J:337207
First Author: NaĂłn D
Year: 2023
Journal: Science
Title: Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria.
Volume: 380
Issue: 6651
Pages: eadh9351
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30017354 | J:270240
First Author: Wang L
Year: 2018
Journal: Cell Metab
Title: Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles.
Volume: 28
Issue: 3
Pages: 400-414.e8
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Publication
24074867 | J:214486
First Author: Schneeberger M
Year: 2013
Journal: Cell
Title: Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Volume: 155
Issue: 1
Pages: 172-87
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Publication
30690319 | J:307565
 
First Author: Hou X
Year: 2019
Journal: Redox Biol
Title: Mitofusin1 in oocyte is essential for female fertility.
Volume: 21
Pages: 101110
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Publication
30882371 | J:273854
 
First Author: Zhou Y
Year: 2019
Journal: J Clin Invest
Title: Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Volume: 130
Pages: 1756-1771
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Publication
27404125 | J:238670
First Author: McFie PJ
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation.
Volume: 478
Issue: 1
Pages: 392-397
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Publication
33813068 | J:316973
 
First Author: Zarei A
Year: 2021
Journal: Bone
Title: Osteolineage depletion of mitofusin2 enhances cortical bone formation in female mice.
Volume: 148
Pages: 115941
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Publication
25201884 | J:318630
First Author: Gall JM
Year: 2015
Journal: J Am Soc Nephrol
Title: Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia.
Volume: 26
Issue: 5
Pages: 1092-102
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22292091 | J:184222
First Author: Gall JM
Year: 2012
Journal: PLoS One
Title: Role of mitofusin 2 in the renal stress response.
Volume: 7
Issue: 1
Pages: e31074
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Publication
24081906 | J:206621
First Author: Chen KH
Year: 2014
Journal: FASEB J
Title: Role of mitofusin 2 (Mfn2) in controlling cellular proliferation.
Volume: 28
Issue: 1
Pages: 382-94
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20335458 | J:159219
First Author: Misko A
Year: 2010
Journal: J Neurosci
Title: Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex.
Volume: 30
Issue: 12
Pages: 4232-40
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16731843 | J:111879
First Author: Soriano FX
Year: 2006
Journal: Diabetes
Title: Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2.
Volume: 55
Issue: 6
Pages: 1783-91
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Publication
26230519 | J:238603
First Author: Kawalec M
Year: 2015
Journal: PLoS One
Title: Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells.
Volume: 10
Issue: 7
Pages: e0134162
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Publication
32788232 | J:294721
 
First Author: Zhou W
Year: 2020
Journal: J Cell Sci
Title: Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton.
Volume: 133
Issue: 17
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Publication
37910431 | J:342938
   
First Author: Franco A
Year: 2023
Journal: Elife
Title: A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Volume: 12
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15985463 | J:99799
First Author: Honda S
Year: 2005
Journal: J Cell Sci
Title: Mutational analysis of action of mitochondrial fusion factor mitofusin-2.
Volume: 118
Issue: Pt 14
Pages: 3153-61
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23941871 | J:203857
First Author: Segalés J
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells.
Volume: 305
Issue: 10
Pages: E1208-21
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Publication
23954742 | J:211375
First Author: Zhang Y
Year: 2013
Journal: Mol Cell Endocrinol
Title: MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2.
Volume: 381
Issue: 1-2
Pages: 230-40
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25870285 | J:221109
First Author: Filadi R
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling.
Volume: 112
Issue: 17
Pages: E2174-81
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Publication
24513856 | J:211366
First Author: Yue W
Year: 2014
Journal: Cell Res
Title: A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30.
Volume: 24
Issue: 4
Pages: 482-96
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32846136 | J:300219
First Author: Tur J
Year: 2020
Journal: Cell Rep
Title: Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity.
Volume: 32
Issue: 8
Pages: 108079
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27239030 | J:238101
First Author: Filadi R
Year: 2016
Journal: Cell Rep
Title: Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.
Volume: 15
Issue: 10
Pages: 2226-2238
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23727017 | J:199253
First Author: Sugiura A
Year: 2013
Journal: Mol Cell
Title: MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2.
Volume: 51
Issue: 1
Pages: 20-34
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24469638 | J:208260
First Author: Debattisti V
Year: 2014
Journal: J Cell Biol
Title: Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion.
Volume: 204
Issue: 3
Pages: 303-12
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31937559 | J:285802
First Author: Harland M
Year: 2020
Journal: J Neurosci
Title: Neuronal Mitochondria Modulation of LPS-Induced Neuroinflammation.
Volume: 40
Issue: 8
Pages: 1756-1765
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24074868 | J:205152
First Author: Dietrich MO
Year: 2013
Journal: Cell
Title: Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity.
Volume: 155
Issue: 1
Pages: 188-99
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32281181 | J:325520
First Author: Carvalho KF
Year: 2020
Journal: FASEB J
Title: Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells.
Volume: 34
Issue: 6
Pages: 7644-7660
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22511781 | J:186517
First Author: Ngoh GA
Year: 2012
Journal: J Biol Chem
Title: Loss of mitofusin 2 promotes endoplasmic reticulum stress.
Volume: 287
Issue: 24
Pages: 20321-32
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22777004 | J:212648
First Author: Chen Y
Year: 2012
Journal: Circ Res
Title: Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.
Volume: 111
Issue: 7
Pages: 863-75
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21285412 | J:185395
First Author: Koshiba T
Year: 2011
Journal: Sci Signal
Title: Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling.
Volume: 4
Issue: 158
Pages: ra7
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23620051 | J:198571
First Author: Chen Y
Year: 2013
Journal: Science
Title: PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Volume: 340
Issue: 6131
Pages: 471-5
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31358769 | J:279297
First Author: Chung KP
Year: 2019
Journal: Nat Commun
Title: Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Volume: 10
Issue: 1
Pages: 3390
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26785495 | J:229454
First Author: Gong G
Year: 2015
Journal: Science
Title: Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Volume: 350
Issue: 6265
Pages: aad2459
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35318101 | J:323885
 
First Author: Hu L
Year: 2022
Journal: Free Radic Biol Med
Title: Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1α-PPARα pathway.
Volume: 183
Pages: 75-88
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24874428 | J:247164
First Author: Song M
Year: 2014
Journal: Circ Res
Title: Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy.
Volume: 115
Issue: 3
Pages: 348-53
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33749882 | J:321379
First Author: Luo N
Year: 2021
Journal: FASEB J
Title: Reduced electron transport chain complex I protein abundance and function in Mfn2-deficient myogenic progenitors lead to oxidative stress and mitochondria swelling.
Volume: 35
Issue: 4
Pages: e21426
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Publication
27206984 | J:237149
First Author: Gautier CA
Year: 2016
Journal: Hum Mol Genet
Title: The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Volume: 25
Issue: 14
Pages: 2972-2984
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22619176 | J:188865
First Author: Zhao T
Year: 2012
Journal: J Biol Chem
Title: Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.
Volume: 287
Issue: 28
Pages: 23615-25
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29774638 | J:332293
First Author: Chun SK
Year: 2018
Journal: Aging Cell
Title: Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.
Volume: 17
Issue: 4
Pages: e12761
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19269351 | J:192155
First Author: de Brito OM
Year: 2009
Journal: Mitochondrion
Title: Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: the role of Ras.
Volume: 9
Issue: 3
Pages: 222-6
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19690333 | J:259230
First Author: Yasukawa K
Year: 2009
Journal: Sci Signal
Title: Mitofusin 2 inhibits mitochondrial antiviral signaling.
Volume: 2
Issue: 84
Pages: ra47
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30260752 | J:327267
First Author: Bell MB
Year: 2019
Journal: J Appl Physiol (1985)
Title: Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.
Volume: 126
Issue: 2
Pages: 341-353
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17693261 | J:132329
First Author: Chen H
Year: 2007
Journal: Cell
Title: Mitochondrial fusion protects against neurodegeneration in the cerebellum.
Volume: 130
Issue: 3
Pages: 548-62
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17035996 | J:113296
First Author: Karbowski M
Year: 2006
Journal: Nature
Title: Role of Bax and Bak in mitochondrial morphogenesis.
Volume: 443
Issue: 7112
Pages: 658-62
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28684211 | J:261224
 
First Author: Nivison MP
Year: 2017
Journal: Exp Neurol
Title: Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression.
Volume: 296
Pages: 49-61
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15899901 | J:281198
First Author: Chen H
Year: 2005
Journal: J Biol Chem
Title: Disruption of fusion results in mitochondrial heterogeneity and dysfunction.
Volume: 280
Issue: 28
Pages: 26185-92
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18974884 | J:143919
First Author: Liesa M
Year: 2008
Journal: PLoS One
Title: Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.
Volume: 3
Issue: 10
Pages: e3613
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Publication
26789249 | J:229092
First Author: Luchsinger LL
Year: 2016
Journal: Nature
Title: Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.
Volume: 529
Issue: 7587
Pages: 528-31
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Publication
19445933 | J:150438
First Author: Uo T
Year: 2009
Journal: Exp Neurol
Title: Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons.
Volume: 218
Issue: 2
Pages: 274-85
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Publication
31659282 | J:304532
First Author: Hong Y
Year: 2020
Journal: Cell Death Differ
Title: RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics.
Volume: 27
Issue: 5
Pages: 1633-1643
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Publication
22914740 | J:188337
First Author: Lee S
Year: 2012
Journal: Hum Mol Genet
Title: Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons.
Volume: 21
Issue: 22
Pages: 4827-35
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Publication
31064883 | J:281841
 
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