|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1201 to 1300 out of 1388 for Dab1

<< First    < Previous  |  Next >    Last >>
0.053s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein
D6RDE3
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
•
•
•
•
•
Publication
28887403 | J:248393
First Author: Santana J
Year: 2017
Journal: Biochem J
Title: The functions of Reelin in membrane trafficking and cytoskeletal dynamics: implications for neuronal migration, polarization and differentiation.
Volume: 474
Issue: 18
Pages: 3137-3165
•
•
•
•
•
Publication
29049379 | J:249311
First Author: Hass H
Year: 2017
Journal: PLoS One
Title: Mathematical model of early Reelin-induced Src family kinase-mediated signaling.
Volume: 12
Issue: 10
Pages: e0186927
•
•
•
•
•
Publication
12737822 | -
First Author: Stolt PC
Year: 2003
Journal: Structure
Title: Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes.
Volume: 11
Issue: 5
Pages: 569-79
•
•
•
•
•
Publication
7798194 | J:39401
First Author: Blaikie P
Year: 1994
Journal: J Biol Chem
Title: A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.
Volume: 269
Issue: 51
Pages: 32031-4
•
•
•
•
•
Publication
7534213 | -
First Author: Bork P
Year: 1995
Journal: Cell
Title: A phosphotyrosine interaction domain.
Volume: 80
Issue: 5
Pages: 693-4
•
•
•
•
•
Publication
7527937 | -
First Author: Kavanaugh WM
Year: 1994
Journal: Science
Title: An alternative to SH2 domains for binding tyrosine-phosphorylated proteins.
Volume: 266
Issue: 5192
Pages: 1862-5
•
•
•
•
•
Protein Domain
IPR006020 | PTB/PI_dom
Type: Domain
Description: Proteins encoding phosphotyrosine binding (PTB) domains function as adaptors or scaffolds to organise the signaling complexes involved in wide-ranging physiological processes including neural development, immunity, tissue homeostasis and cell growth. Due to structural differences, PTB domains are divided into three groups represented by phosphotyrosine-dependent IRS-like, phosphotyrosine-dependent Shc-like, and phosphotyrosine-independent Dab-like PTBs. The last two PTBs have been named as phosphotyrosine interaction domain (PID or PI domain). PID domain has an average length of about 160 amino acids [].The Shc-like PID specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins including growth factor receptors. On the other hand the Dab-like PID domain binds to non-phosphorylated tyrosine residue or even a phenylalanine at the same position []. Most of the ligands for Shc-like PID domains are RTK or cytokine, whereas phosphotyrosine independent Dab-like PID domains seems to mediate other types of signaling pathways, like endocytosis/processing or exocytosis. This domain binds both peptides and headgroups of phosphatidylinositides, utilising two distinct binding motifs to mediate spatial organisation and localisation within cells [, , , ].The 3D structure of PID domain has been solved []. It shares a folding pattern, commonly referred to as the PH-domain "superfold". The core "superfold"consists of seven antiparallel beta strands forming two orthogonal beta sheets. This beta sandwich is capped at the C terminus by an alpha helix. It contains a peptide binding pocket (formed by the beta strand 5 and C-terminal alpha helix) and a highly basic phospholipid binding "crown"(largely composed of residues from loop regions near the N terminus). Both Shcand Dab1 have two additional alpha helices, one of which is located at the Nterminus and the other between beta 1 and beta 2 strands.
•
•
•
•
•
Protein
Q8C142
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
•
•
•
•
•
Protein
Q8K2A1
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
•
•
•
•
•
Protein
Q9D3A8
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
•
•
•
•
•
Protein
O35671
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
•
•
•
•
•
Protein
P97318
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
•
•
•
•
•
Protein
P98078
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
•
•
•
•
•
Protein
Q9DCE6
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
•
•
•
•
•
Protein
Q3TRB6
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
•
•
•
•
•
Protein
Q3TRE6
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
•
•
•
•
•
Protein
Q0PNF0
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
•
•
•
•
•
Protein
D3Z7I6
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
•
•
•
•
•
Protein
E0CZ53
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
•
•
•
•
•
Protein
Q3TN55
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
•
•
•
•
•
Protein
F6VRL0
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
•
•
•
•
•
Protein
E9QL31
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
•
•
•
•
•
Protein
F8WJ71
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: false
•
•
•
•
•
Protein
Q3TMQ2
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
•
•
•
•
•
Protein
B7ZNH1
Organism: Mus musculus/domesticus
Length: 383  
Fragment?: true
•
•
•
•
•
Protein
A2AWA7
Organism: Mus musculus/domesticus
Length: 455  
Fragment?: true
•
•
•
•
•
Protein
E0CXC5
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
•
•
•
•
•
Protein
A2AWB0
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
•
•
•
•
•
Protein
Q9CUY3
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
•
•
•
•
•
Protein
E0CXT5
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
•
•
•
•
•
Protein
D3Z549
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
•
•
•
•
•
Protein
Q3TRI2
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
•
•
•
•
•
Protein
A2AM80
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
•
•
•
•
•
Protein
E0CYH9
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
•
•
•
•
•
Protein
A0A0A0MQI4
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
•
•
•
•
•
Protein
D3Z1E8
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
•
•
•
•
•
Protein
F6TQN9
Organism: Mus musculus/domesticus
Length: 634  
Fragment?: true
•
•
•
•
•
Protein
F2Z465
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
•
•
•
•
•
Protein
H7BX82
Organism: Mus musculus/domesticus
Length: 839  
Fragment?: true
•
•
•
•
•
Protein
E9PX84
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
•
•
•
•
•
Protein
A0A0R4J104
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
•
•
•
•
•
Protein
B2RRQ8
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
•
•
•
•
•
Protein
Q3UGH2
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
•
•
•
•
•
Protein
Q8K2Y9
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
•
•
•
•
•
Protein
Q9QZS3
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
•
•
•
•
•
Protein
Q3UBG2
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
•
•
•
•
•
Protein
Q8BUP8
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
•
•
•
•
•
Protein
O08919
Organism: Mus musculus/domesticus
Length: 604  
Fragment?: false
•
•
•
•
•
Protein
Q3UUV3
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
•
•
•
•
•
Protein
Q80Y77
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
•
•
•
•
•
Protein
Q9R021
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
•
•
•
•
•
Protein
Q3TXH9
Organism: Mus musculus/domesticus
Length: 768  
Fragment?: true
•
•
•
•
•
Protein
Q8R1Y7
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
•
•
•
•
•
Protein
E0CXR5
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: true
•
•
•
•
•
Protein
Q3UH86
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: false
•
•
•
•
•
Protein
Q3ZAX3
Organism: Mus musculus/domesticus
Length: 341  
Fragment?: false
•
•
•
•
•
Protein
Q3T9N0
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
•
•
•
•
•
Protein
A0A1B0GR67
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
•
•
•
•
•
Protein
A0A494B9D6
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
•
•
•
•
•
Protein
A0A1B0GT76
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
•
•
•
•
•
Protein
A0A3B2W7E6
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
•
•
•
•
•
Protein
A0A1Y7VKQ1
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
•
•
•
•
•
Protein
S4R2E3
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
•
•
•
•
•
Protein
A0A087WQC5
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
•
•
•
•
•
Protein
Q05BE7
Organism: Mus musculus/domesticus
Length: 322  
Fragment?: false
•
•
•
•
•
Protein
A0A140T8U6
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
•
•
•
•
•
Protein
P98084
Organism: Mus musculus/domesticus
Length: 750  
Fragment?: false
•
•
•
•
•
Protein
Q9QXJ1
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
•
•
•
•
•
Protein
O88888
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false
•
•
•
•
•
Protein
Q8R1C9
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
•
•
•
•
•
Protein
Q9ERE9
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
•
•
•
•
•
Protein
Q8JZW5
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
•
•
•
•
•
Protein
Q9DBR4
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RPM0
Organism: Mus musculus/domesticus
Length: 738  
Fragment?: false
•
•
•
•
•
Protein
D3Z2I8
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
•
•
•
•
•
Protein
Q3TIZ5
Organism: Mus musculus/domesticus
Length: 758  
Fragment?: false
•
•
•
•
•
Protein
A0A087WRP1
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: true
•
•
•
•
•
Protein
A0A087WPI2
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
•
•
•
•
•
Protein
D3Z5I5
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: true
•
•
•
•
•
Protein
S4R2N9
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
•
•
•
•
•
Protein
E9QPX0
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
•
•
•
•
•
Protein
D3Z7F4
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
•
•
•
•
•
Protein
Q3UFL4
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: true
•
•
•
•
•
Protein
A0A1W2P6Z9
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
•
•
•
•
•
Protein
A2AM67
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
•
•
•
•
•
Protein
Q3U674
Organism: Mus musculus/domesticus
Length: 738  
Fragment?: false
•
•
•
•
•
Protein
Q8CB26
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
•
•
•
•
•
Protein
Q3TER1
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
•
•
•
•
•
Protein
Q3UML5
Organism: Mus musculus/domesticus
Length: 621  
Fragment?: true
•
•
•
•
•
Protein
A0A0R4J2C1
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
•
•
•
•
•
Protein
E9PWH3
Organism: Mus musculus/domesticus
Length: 738  
Fragment?: false
•
•
•
•
•
Protein
A0A087WPS7
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
•
•
•
•
•
Protein
A0A087WQH0
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
•
•
•
•
•
Protein
D3YZV5
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
•
•
•
•
•
Protein
A0A087WNN4
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
•
•
•
•
•
Protein
D3YXZ9
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
•
•
•
•
•
Protein
F6QQP6
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: true
•
•
•
•
•
Protein
F6V8Y6
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
•
•
•
•
•
Protein
Q8BNM8
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom