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Search results 1 to 100 out of 290 for Rif1

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0.042s
Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 2418  
Fragment?: false
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: In Saccharomyces cerevisiae Rif1 interacts with Rif2 and Rap1 to regulate telomere length and establish telomeric silencing []. Despite the protein sequence similarity with yeast Rif1, human Rif1 does not bind to Rap1 and does not accumulate at functional telomeres. Human Rif1 is required for checkpoint mediated arrest of cell cycle progression in response to DNA damage during S-phase (the intra-S-phase checkpoint) and is regulated by ATM and 53BP1 [].
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 731  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2419  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
Publication
First Author: Silverman J
Year: 2004
Journal: Genes Dev
Title: Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.
Volume: 18
Issue: 17
Pages: 2108-19
Publication
First Author: Hardy CF
Year: 1992
Journal: Genes Dev
Title: A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.
Volume: 6
Issue: 5
Pages: 801-14
Publication
First Author: Zimmermann M
Year: 2013
Journal: Science
Title: 53BP1 regulates DSB repair using Rif1 to control 5' end resection.
Volume: 339
Issue: 6120
Pages: 700-4
Publication
First Author: Di Virgilio M
Year: 2013
Journal: Science
Title: Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Volume: 339
Issue: 6120
Pages: 711-5
Publication
First Author: Chapman JR
Year: 2013
Journal: Mol Cell
Title: RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
Volume: 49
Issue: 5
Pages: 858-71
Publication
First Author: Foti R
Year: 2016
Journal: Mol Cell
Title: Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program.
Volume: 61
Issue: 2
Pages: 260-73
Publication
First Author: Cornacchia D
Year: 2012
Journal: EMBO J
Title: Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells.
Volume: 31
Issue: 18
Pages: 3678-90
Publication
First Author: Buonomo SB
Year: 2009
Journal: J Cell Biol
Title: Mammalian Rif1 contributes to replication stress survival and homology-directed repair.
Volume: 187
Issue: 3
Pages: 385-98
Publication    
First Author: Balasubramanian S
Year: 2022
Journal: Elife
Title: Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Volume: 11
Publication
First Author: Mukherjee C
Year: 2019
Journal: Nat Commun
Title: RIF1 promotes replication fork protection and efficient restart to maintain genome stability.
Volume: 10
Issue: 1
Pages: 3287
Publication
First Author: Dan J
Year: 2014
Journal: Dev Cell
Title: Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 7-19
Publication
First Author: Xu D
Year: 2010
Journal: EMBO J
Title: Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication.
Volume: 29
Issue: 18
Pages: 3140-55
Publication
First Author: Moriyama K
Year: 2018
Journal: J Biol Chem
Title: Oligomer formation and G-quadruplex binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture.
Volume: 293
Issue: 10
Pages: 3607-3624
Publication
First Author: Escribano-Díaz C
Year: 2013
Journal: Mol Cell
Title: A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Volume: 49
Issue: 5
Pages: 872-83
Publication
First Author: Adams IR
Year: 2004
Journal: Dev Dyn
Title: Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells.
Volume: 229
Issue: 4
Pages: 733-44
Publication
First Author: Gnan S
Year: 2021
Journal: Nat Commun
Title: Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction.
Volume: 12
Issue: 1
Pages: 2910
Publication
First Author: Callen E
Year: 2013
Journal: Cell
Title: 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Volume: 153
Issue: 6
Pages: 1266-80
Publication
First Author: Mirman Z
Year: 2018
Journal: Nature
Title: 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Volume: 560
Issue: 7716
Pages: 112-116
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Thymus
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Heart
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Lung
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Spleen
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Kidney
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Ovary
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3263428
Stage: TS28
Assay Id: MGI:3618523
Age: postnatal adult
Image: 2
Specimen Label: Sk. Muscle
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Brain
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Thymus
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Heart
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Lung
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Spleen
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Kidney
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Ovary
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:3618517
Assay Type: Western blot
Annotation Date: 2006-04-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3263428
Stage: TS28
Assay Id: MGI:3618525
Age: postnatal adult
Image: 2
Specimen Label: Sk. Muscle
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1738120
Stage: TS20
Assay Id: MGI:3618526
Age: embryonic day 12.5
Image: 2
Specimen Label: Male
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3618515
Assay Type: Northern blot
Annotation Date: 2006-04-05
Strength: Present
Sex: Female
Emaps: EMAPS:1738120
Stage: TS20
Assay Id: MGI:3618526
Age: embryonic day 12.5
Image: 2
Specimen Label: Female
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816866
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816866
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816866
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816866
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816866
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816866
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816866
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3816062
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816866
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-2
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289660
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289660
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289660
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289660
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-1
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5289104
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289660
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-2
Detected: true
Specimen Num: 16