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Search results 1301 to 1394 out of 1394 for Ccn2

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Type Details Score
Publication
30305289 | J:272609
 
First Author: Nantie LB
Year: 2018
Journal: Development
Title: Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.
Volume: 145
Issue: 21
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Publication
34004146 | J:314776
First Author: Yao Z
Year: 2021
Journal: Cell
Title: A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation.
Volume: 184
Issue: 12
Pages: 3222-3241.e26
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Publication
28943241 | J:245870
First Author: Cotton JL
Year: 2017
Journal: Dev Cell
Title: YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme.
Volume: 43
Issue: 1
Pages: 35-47.e4
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Publication
36362374 | J:331266
 
First Author: Abou Nader N
Year: 2022
Journal: Int J Mol Sci
Title: Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.
Volume: 23
Issue: 21
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Publication
28118982 | J:240405
First Author: Zhao L
Year: 2017
Journal: Dev Biol
Title: SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.
Volume: 423
Issue: 1
Pages: 46-56
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Publication
19411759 | J:150452
First Author: Zhou B
Year: 2009
Journal: J Clin Invest
Title: Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.
Volume: 119
Issue: 6
Pages: 1462-76
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Publication
26378152 | J:263568
First Author: Kim GE
Year: 2015
Journal: Cardiovasc Res
Title: LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.
Volume: 108
Issue: 1
Pages: 197-208
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Publication
26952977 | J:235538
First Author: Tomann P
Year: 2016
Journal: Development
Title: Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Volume: 143
Issue: 9
Pages: 1512-22
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Publication
18927151 | J:143588
First Author: Kamiya N
Year: 2008
Journal: Development
Title: BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway.
Volume: 135
Issue: 22
Pages: 3801-11
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Publication
30504829 | J:267596
First Author: Escot S
Year: 2018
Journal: Nat Commun
Title: Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Volume: 9
Issue: 1
Pages: 5082
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Publication
34376651 | J:308983
First Author: Farmer DT
Year: 2021
Journal: Nat Commun
Title: The developing mouse coronal suture at single-cell resolution.
Volume: 12
Issue: 1
Pages: 4797
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Publication
28323616 | J:244106
   
First Author: Lin C
Year: 2017
Journal: Elife
Title: YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
Volume: 6
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Publication
23175628 | J:191071
First Author: Petzold KM
Year: 2013
Journal: Development
Title: Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas.
Volume: 140
Issue: 1
Pages: 126-35
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Publication
23620511 | J:197340
First Author: Chung C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis.
Volume: 110
Issue: 19
Pages: 7732-7
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Publication
27292642 | J:238301
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
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Publication
30037926 | J:266090
First Author: Xia W
Year: 2018
Journal: J Cell Biol
Title: Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.
Volume: 217
Issue: 10
Pages: 3464-3479
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Publication
35951005 | J:334460
First Author: Bando H
Year: 2023
Journal: Hum Mol Genet
Title: Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man.
Volume: 32
Issue: 3
Pages: 367-385
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Publication
31220272 | J:277277
First Author: Zieman AG
Year: 2019
Journal: Hum Mol Genet
Title: Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.
Volume: 28
Issue: 13
Pages: 2255-2270
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Publication
23863479 | J:199301
First Author: Lavado A
Year: 2013
Journal: Development
Title: Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.
Volume: 140
Issue: 16
Pages: 3323-34
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Publication
35247391 | J:323229
First Author: Rosendahl AH
Year: 2022
Journal: J Biol Chem
Title: Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.
Volume: 298
Issue: 4
Pages: 101787
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Publication
29438518 | J:258670
First Author: Mahany EB
Year: 2018
Journal: Endocrinology
Title: Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.
Volume: 159
Issue: 4
Pages: 1718-1733
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Publication
20637190 | J:165751
First Author: Du J
Year: 2010
Journal: Dev Biol
Title: O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.
Volume: 346
Issue: 1
Pages: 25-38
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Publication
37702066 | J:341382
First Author: Wu B
Year: 2023
Journal: J Am Heart Assoc
Title: Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
Volume: 12
Issue: 18
Pages: e029683
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Publication
30228991 | J:283457
 
First Author: Uijtdewilligen PJE
Year: 2018
Journal: Biomed Res Int
Title: Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development.
Volume: 2018
Pages: 9873471
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Publication
21491433 | J:174459
First Author: Boyle MP
Year: 2011
Journal: J Comp Neurol
Title: Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
Volume: 519
Issue: 11
Pages: 2061-89
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Publication
23375831 | J:237827
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
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Publication
22008794 | J:143778
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
29145495 | J:253069
First Author: Hori A
Year: 2017
Journal: PLoS One
Title: Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT2A and 5-HT2B receptors in chondrocytes.
Volume: 12
Issue: 11
Pages: e0188014
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Publication
37629004 | J:339678
 
First Author: Li X
Year: 2023
Journal: Int J Mol Sci
Title: Production, Exacerbating Effect, and EV-Mediated Transcription of Hepatic CCN2 in NASH: Implications for Diagnosis and Therapy of NASH Fibrosis.
Volume: 24
Issue: 16
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GXD Expression
GXD Expression
 
Probe: MGI:6281998
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532605
Age: embryonic day 12.0
Note: Differences in expression from Ccn2 beginning at E12.
Specimen Label: 1a CCN5
Detected: true
Specimen Num: 4
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Publication
19359517 | J:147966
First Author: Riser BL
Year: 2009
Journal: Am J Pathol
Title: CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease.
Volume: 174
Issue: 5
Pages: 1725-34
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GO Term
GO:0032601 | connective tissue growth factor production
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GO Term
GO:0032643 | regulation of connective tissue growth factor production
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GO Term
GO:0032683 | negative regulation of connective tissue growth factor production
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GO Term
GO:0032723 | positive regulation of connective tissue growth factor production
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Publication
11584015 | -
First Author: Chen CC
Year: 2001
Journal: J Biol Chem
Title: The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts.
Volume: 276
Issue: 50
Pages: 47329-37
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Publication
11782444 | -
First Author: Su F
Year: 2002
Journal: Genes Dev
Title: WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Volume: 16
Issue: 1
Pages: 46-57
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Publication
12695522 | -
First Author: Lin CG
Year: 2003
Journal: J Biol Chem
Title: CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family.
Volume: 278
Issue: 26
Pages: 24200-8
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Protein Domain
IPR012395 | IGFBP_CNN
Type: Family
Description: This entry represents a group of IGFBP (insulin-like growth fac-tor (IGF) binding proteins)-related proteins, which have been annotated as the CNN family [, ]. Members of the CCN family are composed of an N-terminal secretory signal peptide followed by four conserved domains with homology to insulin-like growth factor binding protein, von Willebrand factor type C repeat, thrombospondin type 1 repeat, and a C-terminal domain (CT) with heparin-binding motifs and sequence similarity to the C termini of von Willebrand factor and mucin. The CCN family includes CCN1 (CYR61) [], CCN2 (CTGF), CCN3 [], CCN4 (WISP-1) [], CCN5 (WISP-2), and CCN6 (WISP-3).
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Publication
18158569 | J:133412
First Author: Croci S
Year: 2007
Journal: Pathol Oncol Res
Title: Expression of connective tissue growth factor (CTGF/CCN2) in a mouse model of rhabdomyosarcomagenesis.
Volume: 13
Issue: 4
Pages: 336-9
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Publication
30232710 | J:297327
First Author: Ohta K
Year: 2019
Journal: J Cell Commun Signal
Title: CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi.
Volume: 13
Issue: 1
Pages: 113-118
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Publication
34010605 | J:308340
First Author: Van Gucht I
Year: 2021
Journal: Am J Hum Genet
Title: A human importin-β-related disorder: Syndromic thoracic aortic aneurysm caused by bi-allelic loss-of-function variants in IPO8.
Volume: 108
Issue: 6
Pages: 1115-1125
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Publication
38395992 | J:345925
First Author: Brylka LJ
Year: 2024
Journal: Bone Res
Title: Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.
Volume: 12
Issue: 1
Pages: 12
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Publication
25193594 | J:216375
First Author: Riser BL
Year: 2014
Journal: Am J Pathol
Title: Treatment with the matricellular protein CCN3 blocks and/or reverses fibrosis development in obesity with diabetic nephropathy.
Volume: 184
Issue: 11
Pages: 2908-21
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Publication
36596387 | J:333923
 
First Author: Paredes F
Year: 2023
Journal: Free Radic Biol Med
Title: Metabolic regulation of the proteasome under hypoxia by Poldip2 controls fibrotic signaling in vascular smooth muscle cells.
Volume: 195
Pages: 283-297
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Publication
23340735 | J:197953
First Author: Guo F
Year: 2013
Journal: J Invest Dermatol
Title: TAK1 is required for dermal wound healing and homeostasis.
Volume: 133
Issue: 6
Pages: 1646-54
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Publication
22586581 | J:208460
First Author: Fragiadaki M
Year: 2012
Journal: Diabetes
Title: Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: implications for diabetic nephropathy.
Volume: 61
Issue: 9
Pages: 2280-8
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Publication
28433542 | J:296346
First Author: Makino K
Year: 2017
Journal: J Invest Dermatol
Title: Blockade of PDGF Receptors by Crenolanib Has Therapeutic Effect in Patient Fibroblasts and in Preclinical Models of Systemic Sclerosis.
Volume: 137
Issue: 8
Pages: 1671-1681
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Publication
23648563 | J:198745
First Author: Rodrigues-Díez R
Year: 2013
Journal: Lab Invest
Title: The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response.
Volume: 93
Issue: 7
Pages: 812-24
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Publication
22976296 | J:200272
First Author: Faherty N
Year: 2012
Journal: J Cell Sci
Title: CCN2/CTGF increases expression of miR-302 microRNAs, which target the TGFβ type II receptor with implications for nephropathic cell phenotypes.
Volume: 125
Issue: Pt 23
Pages: 5621-9
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Publication
33524540 | J:343052
 
First Author: Singh R
Year: 2021
Journal: Pharmacol Res
Title: Resistin induces cardiac fibroblast-myofibroblast differentiation through JAK/STAT3 and JNK/c-Jun signaling.
Volume: 167
Pages: 105414
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Publication
12826661 | J:85278
First Author: Leu SJ
Year: 2003
Journal: J Biol Chem
Title: Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61).
Volume: 278
Issue: 36
Pages: 33801-8
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Publication
21864682 | J:178242
First Author: Fragiadaki M
Year: 2011
Journal: Matrix Biol
Title: Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo.
Volume: 30
Issue: 7-8
Pages: 396-403
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Publication
18289368 | J:135676
 
First Author: Heath E
Year: 2008
Journal: BMC Dev Biol
Title: Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene.
Volume: 8
Pages: 18
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Publication
9745429 | J:49843
First Author: Baxter RC
Year: 1998
Journal: J Clin Endocrinol Metab
Title: Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily.
Volume: 83
Issue: 9
Pages: 3213
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Protein
P29268
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q64299
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
D3Z5L9
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
O54775
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
P18406
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Protein
Q3U2X7
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
Q3UFJ5
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
Q3TX21
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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