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Search results 1301 to 1400 out of 1471 for Mitf

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Type Details Score
Allele
Mitf<Mi> | MGI:1856085
 
Name: melanogenesis associated transcription factor; microphthalmia
Allele Type: Other
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Allele
Mitf<Mi-wh> | MGI:1856088
 
Name: melanogenesis associated transcription factor; white
Allele Type: Spontaneous
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Publication
16605125 | -
 
First Author: Kitamura Y
Year: 2005
Journal: Novartis Found Symp
Title: MITF and SgIGSF: an essential transcription factor and its target adhesion molecule for development and survival of mast cells.
Volume: 271
Pages: 4-11; discussion 11-4, 95-9
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Publication
14975237 | -
First Author: Lee YN
Year: 2004
Journal: Immunity
Title: The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells.
Volume: 20
Issue: 2
Pages: 145-51
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Publication
11955610 | -
First Author: Takeda K
Year: 2002
Journal: Biochim Biophys Acta
Title: Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations.
Volume: 1574
Issue: 1
Pages: 15-23
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HT Experiment
GSE227055 | A framework to identify functional interactors that contribute to disrupted early retinal development in Vsx2 mutant mice III
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Mitf<Mi-Crc> | MGI:2662140
 
Name: melanogenesis associated transcription factor; microphthalmia MRC Clinical Research Centre
Allele Type: Spontaneous
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Allele
Mitf<mi-bw> | MGI:1856089
 
Name: melanogenesis associated transcription factor; black eyed white
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: CBA/CaCrc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: NZB/Mac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: BALB/cAnN * C3H/HeN
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: BALB/cAnN * C3H/HeN
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: C57BL * DBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C57BL * DBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: NZB/Mac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Allele
Mitf<tm1.1(cre)Mwka> | MGI:6151122
Name: melanogenesis associated transcription factor; targeted mutation 1.1, Mari Wataya-Kaneda
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Mitf<mi-tg> | MGI:1858053
 
Name: melanogenesis associated transcription factor; microphthalmia transgene insertion
Allele Type: Transgenic
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Strain
MGI:5142438 | STOCK Mitf<Rorp>/H
Attribute String: chemically induced mutation, mutant stock
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Allele
Mitf<mi-vga9> | MGI:2449916
 
Name: melanogenesis associated transcription factor; transgenic insertion 9
Allele Type: Transgenic
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Allele
Mitf<mi-ew> | MGI:1856094
 
Name: melanogenesis associated transcription factor; eyeless white
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: CBA/CaCrc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Tg(Dct-lacZ)A12Jkn/?
Background: involves: C3H * C57BL/6 * C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
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DO Term
DOID:0110950 | Waardenburg syndrome type 2A
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DO Term
DOID:0090002 | Tietz syndrome
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Strain
MGI:4357676 | B6.Cg-Mitf<mi-tg>
Attribute String: congenic, mutant strain, transgenic, insertion
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: C3H/HeNCrl * C57BL/6NCrl
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C3H/HeNCrl * C57BL/6NCrl
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: B6.Cg-Mitf
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Tfe3/Tfe3
Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S1/Sv * C57BL/6 * NAW
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C57BL/6Bn * NAW
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Tfe3/Tfe3<+>
Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C57BL/6Bn
Zygosity: hm
Has Mutant Allele: true
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Publication
9806910 | J:50513
First Author: Steingrímsson E
Year: 1998
Journal: Development
Title: The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.
Volume: 125
Issue: 23
Pages: 4607-16
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Allele
Tg(Mitf-cre)7114Gsb | MGI:3778684
Name: transgene insertion 7114, Gregory S Barsh
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Mitf<mi-enu22(398)> | MGI:6162028
Name: melanogenesis associated transcription factor; microphthalmia enu 22(398)
Allele Type: Chemically induced (ENU)
Attribute String: Null/knockout
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Allele
Tg(Mitf-cre)710-59Gsb | MGI:3778683
Name: transgene insertion 710-59, Gregory S Barsh
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
11818452 | -
First Author: Mansky KC
Year: 2002
Journal: J Leukoc Biol
Title: The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
Volume: 71
Issue: 2
Pages: 304-10
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Protein
Q3TZX0
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
A0A0J9YTW5
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
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Publication
8336698 | J:53285
First Author: Zhao GQ
Year: 1993
Journal: Mol Cell Biol
Title: TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation.
Volume: 13
Issue: 8
Pages: 4505-12
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Protein Domain
IPR024101 | TFEC
Type: Family
Description: The MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors includes MITF (microphthalmia-associated transcription factor) and related family members TFE3, TFEB and TFEC []. The transcription factors heterodimerize with each other and recognise the same DNA sequences []. They recognise and bind E-box sequences (3'-CANNTG-5').This entry represents transcription factor EC (TFEC). TFEC can act as a repressor or an activator. It acts as a transcriptional repressor on minimal promoter containing muE3 enhancer sequence []and as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter []. It binds DNA in a homo or heterodimeric form with MITF and TFE3.
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Protein
D3Z219
Organism: Mus musculus/domesticus
Length: 32  
Fragment?: true
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Publication
23159739 | -
First Author: Ofir-Birin Y
Year: 2013
Journal: Mol Cell
Title: Structural switch of lysyl-tRNA synthetase between translation and transcription.
Volume: 49
Issue: 1
Pages: 30-42
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Protein Domain
IPR031867 | MiT/TFE_N
Type: Domain
Description: This entry represents a domain found at the N terminus of the MiT/TFE family members, which include MITF (microphthalmia-associated transcription factor) and its related family members TFE3, TFEB and TFEC []. They are basic helix-loop-helix leucine zipper transcription factors found in chordata. These transcription factors heterodimerize with each other and bind to the E-box core sequence (3'-CANNTG-5') [, ].
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Protein Domain
IPR031889 | AIMP2_LysRS-bd
Type: Domain
Description: This entry represents the lysyl-tRNA synthetase (LysRS) binding domain of AIMP2 (aminoacyl tRNA synthase complex-interacting multifunctional protein 2). LysRS can serve as a transcription regulator that can be released from the cytoplasmic multi-tRNA synthetase complex (MSC) to activate the transcription factor MITF in stimulated mast cells. In quiescent cells, LysRS is held in the MSC via its interactions with AIMP2 [].
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Protein Domain
IPR021802 | MiT/TFE_C
Type: Domain
Description: This entry represents a domain found at the C terminus of the MiT/TFE family members, which include MITF (microphthalmia-associated transcription factor) and its related family members TFE3, TFEB and TFEC []. They are basic helix-loop-helix leucine zipper transcription factors found in chordata. These transcription factors heterodimerize with each other and bind to the E-box core sequence (3'-CANNTG-5') [, ].
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Strain
MGI:5702900 | C3FeJ.Cg-Tg(Mitf-cre)7114Gsb
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:6474345 | C57BL/6J-Mitf<mi-enu22(398)Is>/Mmmh
Attribute String: coisogenic, mutant strain, chemically induced mutation
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Strain
MGI:6423890 | B6.Cg-Mitf<mi-enu22(398)>/Kctt
Attribute String: congenic, mutant strain, chemically induced mutation
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Genotype
Genotype
Symbol: Mitf/Mitf Tfe3/Tfe3
Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Tg(Mitf-cre)7114Gsb
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Protein
E9PWJ9
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
D3Z782
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein
Q60982
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
D3YZM7
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
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Protein
D3Z1X9
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
E9PXZ1
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Publication
26240184 | -
First Author: Nezich CL
Year: 2015
Journal: J Cell Biol
Title: MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.
Volume: 210
Issue: 3
Pages: 435-50
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Strain
MGI:6187661 | C3FeJ.Cg-Adamts9<tm1.1Cvrk> Tg(Mitf-cre)7114Gsb
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Allele
Mitf<Tg(Tff3-Tmem207)2Tamo> | MGI:6287154
Name: melanogenesis associated transcription factor; transgene insertion 2, Takeuchi Tamotsu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Adamts9/Adamts9 Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Adamts9 Tg(Mitf-cre)7114Gsb
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rps6/Rps6<+> Tg(Mitf-cre)7114Gsb/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR024098 | TFEB
Type: Family
Description: The MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors includes MITF (microphthalmia-associated transcription factor) and related family members TFE3, TFEB and TFEC []. The transcription factors heterodimerize with each other and recognise the same DNA sequences []. They recognise and bind E-box sequences (3'-CANNTG-5').In association with TFE3, TFEB activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity []. It also plays a role in the signal transduction processes required for normal vascularisation of the placenta [].
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Publication
27261482 | J:236808
First Author: Virós A
Year: 2016
Journal: Cancer Discov
Title: So You Can Teach Old Fibroblasts New Tricks.
Volume: 6
Issue: 6
Pages: 581-3
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Publication
16936731 | J:112628
First Author: Huan C
Year: 2006
Journal: Nat Immunol
Title: Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity.
Volume: 7
Issue: 10
Pages: 1082-91
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Protein
Q8K420
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
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Protein
A2AEW2
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Strain
MGI:5702876 | C3FeJ.Cg-Gt(ROSA)26Sor<tm1(GNAQ*)Cvkr> Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:3828511 | B6.Cg-Mitf<mi-sp> Mitf<mi-vga9>/Mmmh
Attribute String: congenic, spontaneous mutation, transgenic, insertion, deletion
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf<+> Pax6/Pax6<+>
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Pax6/Pax6
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Pax6/Pax6<+>
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Protein
Q05BT8
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein Domain
IPR024100 | TFE3
Type: Family
Description: The MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors includes MITF (microphthalmia-associated transcription factor) and related family members TFE3, TFEB and TFEC []. The transcription factors heterodimerize with each other and recognise the same DNA sequences []. They recognise and bind E-box sequences (3'-CANNTG-5').This entry represents the transcription factor E3 (TFE3). In association with TFEB, TFE3 activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. It also has also a role in osteoclast development []. TFE3 specifically recognises the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer []. For efficient DNA-binding, TFE3 requires dimerisation with itself or with another MiT/TFE family member, such as TFEB or MITF.
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Strain
MGI:2683686 | C57BL/6-Mitf<mi-ew>/Mitf<mi-sp>/Mmmh
Attribute String: mutant strain, coisogenic, spontaneous mutation
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Strain
MGI:6187662 | C3FeJ.Cg-Adamts9<tm1.1Cvrk> Tg(KRT14-cre)1Amc Tg(Mitf-cre)7114Gsb
Attribute String: transgenic, targeted mutation, congenic, mutant strain
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Strain
MGI:5702880 | C3FeJ.Cg-Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk> Tg(Dct-lacZ)A12Jkn Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Mitf/Mitf
Background: involves: 129S1/Sv * C3H/He * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mitf/Mitf Tg(PAX6)77Ndha/Tg(PAX6)77Ndha
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Dct-lacZ)A12Jkn/? Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor Tg(Dct-lacZ)A12Jkn Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Adamts9/Adamts9 Tg(KRT14-cre)1Amc/? Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Adamts9 Tg(KRT14-cre)1Amc Tg(Mitf-cre)7114Gsb
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)710-59Gsb/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)7114Gsb/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
7575467 | J:29059
 
First Author: Tomita M
Year: 1995
Journal: Biochem J
Title: Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes.
Volume: 311 ( Pt 1)
Pages: 293-7
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Publication
8666281 | J:33631
First Author: Chinery R
Year: 1996
Journal: Gene
Title: The gene encoding mouse intestinal trefoil factor: structural organization, partial sequence analysis and mapping to murine chromosome 17q.
Volume: 171
Issue: 2
Pages: 249-53
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Publication
28614705 | J:277951
First Author: Mujahid N
Year: 2017
Journal: Cell Rep
Title: A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin.
Volume: 19
Issue: 11
Pages: 2177-2184
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Publication
29463842 | J:267935
First Author: Bagati A
Year: 2018
Journal: Cell Death Differ
Title: FOXQ1 controls the induced differentiation of melanocytic cells.
Volume: 25
Issue: 6
Pages: 1040-1049
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