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Search results 1 to 100 out of 264 for Pdk1

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Category: Publication
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Type Details Score
Publication
32366272 | J:305176
First Author: Wei Y
Year: 2020
Journal: Mol Brain
Title: PDK1 regulates the survival of the developing cortical interneurons.
Volume: 13
Issue: 1
Pages: 65
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Publication
31578203 | J:282101
First Author: Geue S
Year: 2019
Journal: Blood
Title: Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
Volume: 134
Issue: 21
Pages: 1847-1858
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Publication
17371830 | J:134712
First Author: Primo L
Year: 2007
Journal: J Cell Biol
Title: Essential role of PDK1 in regulating endothelial cell migration.
Volume: 176
Issue: 7
Pages: 1035-47
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Publication
33276084 | J:301062
 
First Author: Wang H
Year: 2021
Journal: Neurobiol Dis
Title: Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system.
Volume: 148
Pages: 105212
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Publication
37561545 | J:346253
First Author: Li C
Year: 2023
Journal: FASEB J
Title: Deficiency of Pdk1 drives heart failure by impairing taurine homeostasis through Slc6a6.
Volume: 37
Issue: 9
Pages: e23134
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Publication
34646383 | J:314118
First Author: Feng P
Year: 2021
Journal: Theranostics
Title: The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.
Volume: 11
Issue: 19
Pages: 9503-9518
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Publication
34789718 | J:314587
First Author: Zhang S
Year: 2021
Journal: Cell Death Dis
Title: TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway.
Volume: 12
Issue: 12
Pages: 1086
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Publication
32048762 | J:310893
First Author: Xiao D
Year: 2020
Journal: J Cell Biochem
Title: PDK1 is important lipid kinase for RANKL-induced osteoclast formation and function via the regulation of the Akt-GSK3β-NFATc1 signaling cascade.
Volume: 121
Issue: 11
Pages: 4542-4557
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Publication
16642023 | J:109010
First Author: Hashimoto N
Year: 2006
Journal: Nat Genet
Title: Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.
Volume: 38
Issue: 5
Pages: 589-93
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Publication
16517405 | J:129657
First Author: Kim JW
Year: 2006
Journal: Cell Metab
Title: HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Volume: 3
Issue: 3
Pages: 177-85
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Publication
21074460 | J:166834
First Author: Park SG
Year: 2010
Journal: Immunity
Title: T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells.
Volume: 33
Issue: 5
Pages: 791-803
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Publication
34552205 | J:331530
First Author: Kang HJ
Year: 2021
Journal: Exp Mol Med
Title: Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes.
Volume: 53
Issue: 9
Pages: 1390-1401
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Publication
31208986 | J:278386
First Author: Li C
Year: 2019
Journal: Biochem J
Title: Metabolic remodeling of cardiomyocytes identified in phosphoinositide-dependent kinase 1-deficient mice.
Volume: 476
Issue: 13
Pages: 1943-1954
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Publication
29991705 | J:268502
First Author: Zhang B
Year: 2018
Journal: Sci Rep
Title: Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation.
Volume: 8
Issue: 1
Pages: 10415
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Publication
21411764 | J:172411
First Author: Dunford EC
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation.
Volume: 300
Issue: 6
Pages: R1487-93
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Publication
27189088 | J:239927
 
First Author: Semba H
Year: 2016
Journal: Nat Commun
Title: HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Volume: 7
Pages: 11635
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Publication
30482839 | J:274759
First Author: Klyuyeva A
Year: 2019
Journal: J Biol Chem
Title: Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex.
Volume: 294
Issue: 3
Pages: 838-851
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Publication
25991547 | J:232907
First Author: Hou X
Year: 2015
Journal: J Cell Sci
Title: Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.
Volume: 128
Issue: 13
Pages: 2319-29
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Publication
28182733 | J:245919
First Author: Halvarsson C
Year: 2017
Journal: PLoS One
Title: Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function.
Volume: 12
Issue: 2
Pages: e0171714
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Publication
32393635 | J:288808
First Author: Hosooka T
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B4 axis.
Volume: 117
Issue: 21
Pages: 11674-11684
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Publication
36717164 | J:337865
First Author: Leung CLK
Year: 2023
Journal: Physiol Genomics
Title: Analysis of a genetic region affecting mouse body weight.
Volume: 55
Issue: 3
Pages: 132-146
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Publication
22195962 | J:196247
First Author: Hitosugi T
Year: 2011
Journal: Mol Cell
Title: Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism.
Volume: 44
Issue: 6
Pages: 864-77
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Publication
25437876 | J:220040
First Author: Gerriets VA
Year: 2015
Journal: J Clin Invest
Title: Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Volume: 125
Issue: 1
Pages: 194-207
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Publication
17456549 | J:124173
First Author: Bone HK
Year: 2007
Journal: J Cell Sci
Title: Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis.
Volume: 120
Issue: Pt 10
Pages: 1752-62
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Publication
15554902 | J:117521
First Author: Mora A
Year: 2005
Journal: Biochem J
Title: Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure.
Volume: 385
Issue: Pt 3
Pages: 639-48
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Publication
33773101 | J:303714
First Author: Heinemann-Yerushalmi L
Year: 2021
Journal: Dev Cell
Title: BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development.
Volume: 56
Issue: 8
Pages: 1182-1194.e6
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Publication
16166629 | J:101366
First Author: Tominaga Y
Year: 2005
Journal: Mol Cell Biol
Title: Translational deregulation in PDK-1-/- embryonic stem cells.
Volume: 25
Issue: 19
Pages: 8465-75
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Publication
33106477 | J:314146
First Author: Gao W
Year: 2020
Journal: Cell Death Dis
Title: Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.
Volume: 11
Issue: 10
Pages: 919
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Publication
32979304 | J:297236
First Author: Yang ZH
Year: 2020
Journal: Mol Cell
Title: A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Volume: 80
Issue: 2
Pages: 296-310.e6
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Publication
37301463 | J:337927
 
First Author: Kawakami H
Year: 2023
Journal: Dev Biol
Title: Sall4 restricts glycolytic metabolism in limb buds through transcriptional regulation of glycolytic enzyme genes.
Volume: 501
Pages: 28-38
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Publication
14749367 | J:87682
First Author: Remy I
Year: 2004
Journal: Mol Cell Biol
Title: Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.
Volume: 24
Issue: 4
Pages: 1493-504
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Publication
33052068 | J:304555
First Author: Zamfirescu RC
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.
Volume: 320
Issue: 1
Pages: C30-C44
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Publication
35726058 | J:335574
First Author: Dong X
Year: 2022
Journal: Nat Neurosci
Title: Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex.
Volume: 25
Issue: 7
Pages: 865-875
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Publication
28162974 | J:239679
First Author: Vila IK
Year: 2017
Journal: Cancer Cell
Title: A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.
Volume: 31
Issue: 2
Pages: 208-224
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Publication
31789590 | J:299728
   
First Author: Travisano SI
Year: 2019
Journal: Elife
Title: Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.
Volume: 8
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Publication
26633882 | J:269511
   
First Author: Roy A
Year: 2015
Journal: Elife
Title: Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.
Volume: 4
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Publication
27445154 | J:234630
First Author: Bonney S
Year: 2016
Journal: J Neurosci
Title: Diverse Functions of Retinoic Acid in Brain Vascular Development.
Volume: 36
Issue: 29
Pages: 7786-801
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Publication
34767447 | J:315981
First Author: Torregrosa-Carrión R
Year: 2021
Journal: Sci Adv
Title: Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.
Volume: 7
Issue: 46
Pages: eabj5445
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Publication
33665549 | J:306925
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
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Publication
26856890 | J:231532
First Author: Lange C
Year: 2016
Journal: EMBO J
Title: Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Volume: 35
Issue: 9
Pages: 924-41
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Publication
21270129 | J:170943
First Author: Hölscher M
Year: 2011
Journal: J Biol Chem
Title: Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury.
Volume: 286
Issue: 13
Pages: 11185-94
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Publication
31142573 | J:276713
First Author: Cargill K
Year: 2019
Journal: J Am Soc Nephrol
Title: Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.
Volume: 30
Issue: 7
Pages: 1192-1205
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Publication
20185832 | J:162597
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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Publication
27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
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Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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Publication
31202927 | J:281175
 
First Author: Yorgan TA
Year: 2019
Journal: Bone
Title: Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.
Volume: 127
Pages: 155-163
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
23444402 | J:197452
First Author: Chen X
Year: 2013
Journal: Blood
Title: PDK1 regulates platelet activation and arterial thrombosis.
Volume: 121
Issue: 18
Pages: 3718-26
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16825708 | J:116874
First Author: Sandu C
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.
Volume: 291
Issue: 5
Pages: G868-76
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Publication
24979759 | J:212161
First Author: Baracho GV
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PDK1 regulates B cell differentiation and homeostasis.
Volume: 111
Issue: 26
Pages: 9573-8
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Publication
16243031 | J:102216
First Author: Bayascas JR
Year: 2005
Journal: Curr Biol
Title: Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
Volume: 15
Issue: 20
Pages: 1839-46
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Publication
28694518 | J:270960
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
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Publication
29420689 | J:285763
First Author: Xu M
Year: 2019
Journal: Cereb Cortex
Title: PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice.
Volume: 29
Issue: 3
Pages: 1185-1198
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Publication
25781322 | J:229632
First Author: Han Z
Year: 2015
Journal: PLoS One
Title: Deletion of PDK1 causes cardiac sodium current reduction in mice.
Volume: 10
Issue: 3
Pages: e0122436
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Publication
17077298 | J:129748
First Author: Rexhepaj R
Year: 2006
Journal: FASEB J
Title: Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.
Volume: 20
Issue: 13
Pages: 2214-22
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Publication
21063107 | J:178435
First Author: Shumilina E
Year: 2010
Journal: Cell Physiol Biochem
Title: Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells.
Volume: 26
Issue: 4-5
Pages: 699-706
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Publication
19429709 | J:150014
First Author: Ito K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PDK1 coordinates survival pathways and beta-adrenergic response in the heart.
Volume: 106
Issue: 21
Pages: 8689-94
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