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Search results 401 to 499 out of 499 for Adar

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Type Details Score
Publication
23571754 | J:200651
First Author: García-López J
Year: 2013
Journal: Nucleic Acids Res
Title: Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos.
Volume: 41
Issue: 10
Pages: 5483-93
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Publication
24882218 | J:222665
First Author: Rajsbaum R
Year: 2014
Journal: Immunity
Title: Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Volume: 40
Issue: 6
Pages: 880-95
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Publication
32362246 | J:321254
First Author: Moore JB 4th
Year: 2020
Journal: Circ Res
Title: The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development.
Volume: 127
Issue: 4
Pages: 550-552
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Publication
35859177 | J:331943
First Author: Hubbard NW
Year: 2022
Journal: Nature
Title: ADAR1 mutation causes ZBP1-dependent immunopathology.
Volume: 607
Issue: 7920
Pages: 769-775
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Publication
33983932 | J:306164
First Author: Kim JI
Year: 2021
Journal: PLoS Genet
Title: RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.
Volume: 17
Issue: 5
Pages: e1009516
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Publication
23622242 | J:197985
First Author: Ota H
Year: 2013
Journal: Cell
Title: ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing.
Volume: 153
Issue: 3
Pages: 575-89
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Publication
34380029 | J:310901
First Author: de Reuver R
Year: 2021
Journal: Cell Rep
Title: ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
Volume: 36
Issue: 6
Pages: 109500
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Publication
34686350 | J:320929
First Author: Karki R
Year: 2021
Journal: Cell Rep
Title: ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Volume: 37
Issue: 3
Pages: 109858
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Publication
36458554 | J:333559
 
First Author: Rupani DN
Year: 2023
Journal: Development
Title: Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Volume: 150
Issue: 2
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Publication
31924792 | J:288683
First Author: Gacem N
Year: 2020
Journal: Nat Commun
Title: ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.
Volume: 11
Issue: 1
Pages: 198
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
21615684 | J:186609
First Author: Singh M
Year: 2011
Journal: Genes Brain Behav
Title: Altered ADAR 2 equilibrium and 5HT(2C) R editing in the prefrontal cortex of ADAR 2 transgenic mice.
Volume: 10
Issue: 6
Pages: 637-47
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Publication
31039163 | J:275381
First Author: Altaf F
Year: 2019
Journal: PLoS One
Title: Modulation of ADAR mRNA expression in patients with congenital heart defects.
Volume: 14
Issue: 4
Pages: e0200968
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Publication
2689170 | -
First Author: Kessler E
Year: 1989
Journal: Eur J Biochem
Title: Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a 55-kDa enhancer glycoprotein.
Volume: 186
Issue: 1-2
Pages: 115-21
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Pathway
R-MMU-77042 | Formation of editosomes by ADAR proteins
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Publication
24385426 | J:205586
First Author: Annayev Y
Year: 2014
Journal: J Biol Chem
Title: Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression.
Volume: 289
Issue: 8
Pages: 5013-24
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Publication
- | J:208319
     
First Author: Annayev Y
Year: 2014
Journal: MGI Direct Data Submission
Title: Gene model 129 (gm129) encodes a novel transcriptional repressor that modulates circadian gene expression
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Publication
10587515 | J:69849
First Author: Chen L
Year: 1999
Journal: J Clin Invest
Title: Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis.
Volume: 104
Issue: 11
Pages: 1517-25
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Allele
Adar<tm1Smoc> | MGI:7288130
Name: adenosine deaminase, RNA-specific; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:891999 | Adarb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q91ZS8
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
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Publication
26759233 | J:231328
First Author: Marmary Y
Year: 2016
Journal: Cancer Res
Title: Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation.
Volume: 76
Issue: 5
Pages: 1170-80
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Publication
28027584 | J:273939
First Author: Lanton T
Year: 2017
Journal: Hepatology
Title: Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis.
Volume: 65
Issue: 5
Pages: 1600-1611
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Publication
19153606 | J:145851
First Author: Shachar S
Year: 2009
Journal: EMBO J
Title: Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals.
Volume: 28
Issue: 4
Pages: 383-93
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Protein
Q99MU3
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
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Allele
Htr2c<tm1Arte> | MGI:5751109
 
Name: 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, TaconicArtemis
Allele Type: Targeted
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Publication
22383887 | J:183405
First Author: Reizel Y
Year: 2012
Journal: PLoS Genet
Title: Cell lineage analysis of the mammalian female germline.
Volume: 8
Issue: 2
Pages: e1002477
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HT Experiment
GSE92870 | Testicular adenosine to inosine RNA editing in the mouse
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
25257581 | J:228775
First Author: Bombail V
Year: 2014
Journal: Eur J Neurosci
Title: Prevention of 5-hydroxytryptamine2C receptor RNA editing and alternate splicing in C57BL/6 mice activates the hypothalamic-pituitary-adrenal axis and alters mood.
Volume: 40
Issue: 11
Pages: 3663-73
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Genotype
Genotype
Symbol: Htr2c/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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HT Experiment
E-GEOD-62917 | The RNA editing enzyme ADAR1 is a key regulatory of innate immune responses to RNA
Series Id: GSE62917
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
10836796 | -
First Author: Chen CX
Year: 2000
Journal: RNA
Title: A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.
Volume: 6
Issue: 5
Pages: 755-67
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Protein Domain
IPR044460 | ADAR3_DSRM_1
Type: Domain
Description: Adenosine-to-inosine (A-to-I) editing is a post-transcriptional modification of RNA which changes its sequence, coding potential and secondary structure. This reaction is catalysed by the adenosine deaminase acting on RNA (ADAR) proteins, ADAR1 and ADAR2 []. ADAR3 (also known as RED2 or ADARB2) prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. It is capable of binding to both dsRNA and ssRNA. Moreover, ADAR3 lacks editing activity for currently known substrate RNAs, and may have an inactive editase domain. [].ADAR3 contains two double-stranded RNA binding motifs (DSRMs) and a C-terminal RNA-specific adenosine-deaminase (editase) domain. This entry describes the first DSRM.
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HT Experiment
GSE94388 | RNA editing is the essential function of ADAR1 and, in the absence of MDA5, is dispensable for normal adult homeostasis [RNAseq (Fetal Brain)]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE94387 | RNA editing is the essential function of ADAR1 and, in the absence of MDA5, is dispensable for normal adult homeostasis [RNAseq (Adult Brain)]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
10675613 | J:60373
First Author: Maas S
Year: 2000
Journal: Gene
Title: Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1.
Volume: 243
Issue: 1-2
Pages: 59-66
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Publication
30087110 | J:266328
 
First Author: Jain M
Year: 2018
Journal: EMBO J
Title: RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure.
Volume: 37
Issue: 19
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HT Experiment
GSE220628 | The phenotype of the most common human ADAR1p150 Za domain mutation P193A in mice is incompletely penetrant
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE200854 | ADAR1 mutation causes ZBP1-dependent immunopathology
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q9JI20
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein
Q3UY54
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein
Q8BQZ3
Organism: Mus musculus/domesticus
Length: 701  
Fragment?: false
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Protein
Q6PB89
Organism: Mus musculus/domesticus
Length: 701  
Fragment?: false
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Publication
29719497 | J:264218
 
First Author: Mladenova D
Year: 2018
Journal: Front Neurosci
Title: Adar3 Is Involved in Learning and Memory in Mice.
Volume: 12
Pages: 243
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Publication
9020165 | J:73348
First Author: Liu Y
Year: 1997
Journal: J Biol Chem
Title: Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase.
Volume: 272
Issue: 7
Pages: 4419-28
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Publication
24906008 | J:213995
 
First Author: Hood JL
Year: 2014
Journal: Mol Cell Neurosci
Title: Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions.
Volume: 61
Pages: 97-109
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Publication
28082424 | J:252274
First Author: Behm M
Year: 2017
Journal: J Cell Sci
Title: Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development.
Volume: 130
Issue: 4
Pages: 745-753
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HT Experiment
E-GEOD-71042 | ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis [RNA-seq]
Series Id: GSE71042
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-58917 | RNA Sequencing Quantitative Analysis and identification of RNA editing sites of Wild Type and ADAR1 editing deficient (ADAR1E861A) murine fetal liver RNA
Series Id: GSE58917
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-61067 | ADAR2 reproducibly changes abundance and sequence of mature microRNAs in the mouse brain [gene expression]
Series Id: GSE61067
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-61066 | ADAR2 reproducibly changes abundance and sequence of mature microRNAs in the mouse brain [RNA-Seq]
Series Id: GSE61066
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
38299128 | J:345660
 
First Author: Milham LT
Year: 2023
Journal: Front Mol Neurosci
Title: Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer's disease by capillary western blotting.
Volume: 16
Pages: 1338065
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Publication
32603639 | -
First Author: Heraud-Farlow JE
Year: 2020
Journal: Open Biol
Title: What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs.
Volume: 10
Issue: 7
Pages: 200085
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