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Search results 101 to 200 out of 218 for Mfn1

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Type Details Score
Publication
27404125 | J:238670
First Author: McFie PJ
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation.
Volume: 478
Issue: 1
Pages: 392-397
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Publication
21245373 | J:170619
First Author: Papanicolaou KN
Year: 2011
Journal: Mol Cell Biol
Title: Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes.
Volume: 31
Issue: 6
Pages: 1309-28
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Publication
36050466 | J:328119
First Author: Yoshida Y
Year: 2022
Journal: Sci Rep
Title: Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Volume: 12
Issue: 1
Pages: 14883
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Publication
24686499 | J:211187
 
First Author: Khacho M
Year: 2014
Journal: Nat Commun
Title: Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.
Volume: 5
Pages: 3550
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Publication
36598990 | J:337889
First Author: Chen Z
Year: 2023
Journal: Sci Adv
Title: Lactate metabolism is essential in early-onset mitochondrial myopathy.
Volume: 9
Issue: 1
Pages: eadd3216
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Publication
23727017 | J:199253
First Author: Sugiura A
Year: 2013
Journal: Mol Cell
Title: MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2.
Volume: 51
Issue: 1
Pages: 20-34
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Publication
19690333 | J:259230
First Author: Yasukawa K
Year: 2009
Journal: Sci Signal
Title: Mitofusin 2 inhibits mitochondrial antiviral signaling.
Volume: 2
Issue: 84
Pages: ra47
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Publication
26711011 | J:228496
First Author: Zhang Y
Year: 2016
Journal: Mol Cell
Title: Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.
Volume: 61
Issue: 1
Pages: 111-24
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Publication
36473917 | J:332039
First Author: Kwek XY
Year: 2022
Journal: Sci Rep
Title: Role of cardiac mitofusins in cardiac conduction following simulated ischemia-reperfusion.
Volume: 12
Issue: 1
Pages: 21049
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Publication
29107503 | J:257082
First Author: Song M
Year: 2017
Journal: Cell Metab
Title: Abrogating Mitochondrial Dynamics in Mouse Hearts Accelerates Mitochondrial Senescence.
Volume: 26
Issue: 6
Pages: 872-883.e5
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Publication
35172139 | J:327092
First Author: Wani GA
Year: 2022
Journal: Cell Rep
Title: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.
Volume: 38
Issue: 7
Pages: 110370
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Publication
32220306 | J:287241
First Author: Gӧbel J
Year: 2020
Journal: Cell Metab
Title: Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling.
Volume: 31
Issue: 4
Pages: 791-808.e8
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Publication
30084972 | J:266880
First Author: Huang X
Year: 2018
Journal: Hum Mol Genet
Title: CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Volume: 27
Issue: 22
Pages: 3881-3900
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Publication
21160028 | J:171176
First Author: Brooks C
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.
Volume: 300
Issue: 3
Pages: C447-55
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Publication
32236517 | J:291341
 
First Author: Horn A
Year: 2020
Journal: J Cell Biol
Title: Mitochondrial fragmentation enables localized signaling required for cell repair.
Volume: 219
Issue: 5
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Publication
18974884 | J:143919
First Author: Liesa M
Year: 2008
Journal: PLoS One
Title: Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.
Volume: 3
Issue: 10
Pages: e3613
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Publication
33074106 | J:298900
   
First Author: Franco A
Year: 2020
Journal: Elife
Title: Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
Volume: 9
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Publication
19445933 | J:150438
First Author: Uo T
Year: 2009
Journal: Exp Neurol
Title: Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons.
Volume: 218
Issue: 2
Pages: 274-85
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Publication
22482729 | J:184460
First Author: Garedew A
Year: 2012
Journal: Cell Metab
Title: Mitochondrial dynamics, biogenesis, and function are coordinated with the cell cycle by APC/C CDH1.
Volume: 15
Issue: 4
Pages: 466-79
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Publication
23620051 | J:198571
First Author: Chen Y
Year: 2013
Journal: Science
Title: PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Volume: 340
Issue: 6131
Pages: 471-5
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Publication
19360003 | J:149906
First Author: Tondera D
Year: 2009
Journal: EMBO J
Title: SLP-2 is required for stress-induced mitochondrial hyperfusion.
Volume: 28
Issue: 11
Pages: 1589-600
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Publication
32315597 | J:296538
First Author: Herkenne S
Year: 2020
Journal: Cell Metab
Title: Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1.
Volume: 31
Issue: 5
Pages: 987-1003.e8
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Publication
25600785 | J:219969
First Author: Song M
Year: 2015
Journal: Cell Metab
Title: Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts.
Volume: 21
Issue: 2
Pages: 273-85
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Publication
24127597 | J:201956
First Author: Ichinohe T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection.
Volume: 110
Issue: 44
Pages: 17963-8
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Publication
31675497 | J:339075
First Author: Fan KQ
Year: 2019
Journal: Cell
Title: Stress-Induced Metabolic Disorder in Peripheral CD4(+) T Cells Leads to Anxiety-like Behavior.
Volume: 179
Issue: 4
Pages: 864-879.e19
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Publication
24091702 | J:202826
First Author: Kasahara A
Year: 2013
Journal: Science
Title: Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling.
Volume: 342
Issue: 6159
Pages: 734-7
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Publication
36125902 | J:332020
 
First Author: Wang X
Year: 2022
Journal: J Clin Invest
Title: A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle.
Volume: 132
Issue: 23
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Publication
24282027 | J:204661
First Author: Stafa K
Year: 2014
Journal: Hum Mol Genet
Title: Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.
Volume: 23
Issue: 8
Pages: 2055-77
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Publication
19168699 | J:164708
First Author: Waxman AB
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins.
Volume: 41
Issue: 4
Pages: 385-96
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Publication
38088064 | J:343469
 
First Author: Ding Y
Year: 2023
Journal: Development
Title: Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility.
Volume: 150
Issue: 23
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Publication
19578372 | J:158142
First Author: Ishihara N
Year: 2009
Journal: Nat Cell Biol
Title: Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Volume: 11
Issue: 8
Pages: 958-66
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Publication
26472072 | J:226977
First Author: Moriya M
Year: 2015
Journal: Hum Mol Genet
Title: Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.
Volume: 24
Issue: 25
Pages: 7349-60
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Publication
36167966 | J:329326
First Author: Marta C
Year: 2022
Journal: Sci Rep
Title: Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos.
Volume: 12
Issue: 1
Pages: 16152
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Publication
36754021 | J:333326
First Author: Suh J
Year: 2023
Journal: Cell Metab
Title: Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis.
Volume: 35
Issue: 2
Pages: 345-360.e7
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Publication
28413018 | J:240526
First Author: Hall EA
Year: 2017
Journal: Am J Hum Genet
Title: PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
Volume: 100
Issue: 5
Pages: 706-724
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Publication
37493331 | J:341543
First Author: Meng TG
Year: 2023
Journal: Adv Sci (Weinh)
Title: NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition.
Volume: 10
Issue: 27
Pages: e2301940
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Publication
25348719 | J:224310
First Author: Ishihara T
Year: 2015
Journal: Mol Cell Biol
Title: Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Volume: 35
Issue: 1
Pages: 211-23
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Publication
22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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Publication
27166947 | J:235368
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
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Publication
27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
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Publication
30333037 | J:267504
First Author: Kiyama T
Year: 2018
Journal: Mol Neurodegener
Title: Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.
Volume: 13
Issue: 1
Pages: 56
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Publication
35293971 | J:331835
First Author: Salazar-Petres E
Year: 2022
Journal: Biol Reprod
Title: Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice†.
Volume: 106
Issue: 6
Pages: 1292-1311
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Publication
27689697 | J:235644
First Author: Wu Y
Year: 2016
Journal: PLoS Genet
Title: Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Volume: 12
Issue: 9
Pages: e1006355
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
21873635 | J:265628
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
36936780 | J:340971
First Author: Shahin S
Year: 2023
Journal: iScience
Title: MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Volume: 26
Issue: 3
Pages: 106270
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Protein
Q811U4
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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HT Experiment
E-GEOD-74888 | Effect of deletion of liver Mitofusin 1 (Mfn1) on energy metabolism in high fat diet fed mice
Series Id: GSE74888
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Mfn1<em2Smoc> | MGI:7291057
Name: mitofusin 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Chen H (2003)
Description: Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
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Allele
Mfn1<em1Smoc> | MGI:7291056
Name: mitofusin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(Mfn1-EGFP)HP51Gsat | MGI:4847231
Name: transgene insertion HP51, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004007 | STOCK Tg(Mfn1-EGFP)HP51Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
12759376 | -
First Author: Santel A
Year: 2003
Journal: J Cell Sci
Title: Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.
Volume: 116
Issue: Pt 13
Pages: 2763-74
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Publication
12475957 | -
First Author: Legros F
Year: 2002
Journal: Mol Biol Cell
Title: Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.
Volume: 13
Issue: 12
Pages: 4343-54
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Publication
21248201 | -
First Author: Head BP
Year: 2011
Journal: Mol Biol Cell
Title: A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans.
Volume: 22
Issue: 6
Pages: 831-41
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Protein Domain
IPR027088 | Mitofusin-1
Type: Family
Description: Mitofusin-1 (MNF1) is an essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression of MNF1 induces the formation of mitochondrial networks [, , , ]. This entry includes the protein Marf from Drosophila (also known as Mitofusin) and the closely related protein fzo-1 from C. elegans, which is a transmembrane GTPase reported to be encoded by a mitochondrial fusion gene [].
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Protein
F6XRI9
Organism: Mus musculus/domesticus
Length: 319  
Fragment?: true
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Publication
28746876 | J:254859
First Author: Huang G
Year: 2017
Journal: Cell Rep
Title: WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion.
Volume: 20
Issue: 4
Pages: 923-934
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Publication
27239030 | J:238101
First Author: Filadi R
Year: 2016
Journal: Cell Rep
Title: Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.
Volume: 15
Issue: 10
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