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Search results 301 to 319 out of 319 for Sub1

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Type Details Score
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap RRO077, BayGenomics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap OST388102, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap RRO179, BayGenomics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap RRO096, BayGenomics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap RRO167, BayGenomics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap OST248268, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap PST21038, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap AL0768, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap P144A06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap EUCE00123g02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: SUB1 homolog, transcriptional regulator; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: SUB1 homolog, transcriptional regulator; gene trap E076A07, German Gene Trap Consortium
Allele Type: Gene trapped
Genotype
Symbol: Sub1/Sub1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
GO Term
Publication
First Author: Calvo O
Year: 2005
Journal: EMBO J
Title: The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription.
Volume: 24
Issue: 5
Pages: 1009-20
Protein Domain
Type: Family
Description: This entry represents a group of RNA polymerase II transcriptional coactivators, including Sub1 from budding yeasts, Tcp4 from animals and KIWI/KELP from plants.Tcp4, also known as p15, is a coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. It has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain []. The DNA-binding activity of the carboxy-terminal is disguised by the amino-terminal p15 domain. Activity is controlled by protein kinases that target the regulatory domain.Sub1 facilitates elongation by influencing enzymes that modify RNAP II (RNA polymerase II) []. It is required for NHEJ repair of DSBs in plasmid DNA, but not in chromosomal DNA [].KELP has been shown to bind to movement protein (MP) of tomato mosaic virus (ToMV) and interferes with virus cell-to-cell movement [].
Publication
First Author: Kretzschmar M
Year: 1994
Journal: Cell
Title: A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators.
Volume: 78
Issue: 3
Pages: 525-34
Publication
First Author: Sasaki N
Year: 2009
Journal: Mol Plant Pathol
Title: Over-expression of putative transcriptional coactivator KELP interferes with Tomato mosaic virus cell-to-cell movement.
Volume: 10
Issue: 2
Pages: 161-73