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Search results 101 to 200 out of 221 for Eif2ak3

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Category: Publication
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Type Details Score
Publication
21917591 | J:273445
First Author: Teske BF
Year: 2011
Journal: Mol Biol Cell
Title: The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
Volume: 22
Issue: 22
Pages: 4390-405
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Publication
22813743 | J:196023
First Author: Trinh MA
Year: 2012
Journal: Cell Rep
Title: Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.
Volume: 1
Issue: 6
Pages: 676-88
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Publication
15542627 | J:94221
First Author: Baltzis D
Year: 2004
Journal: J Virol
Title: Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR.
Volume: 78
Issue: 23
Pages: 12747-61
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Publication
21419175 | J:175009
First Author: Farmaki E
Year: 2011
Journal: Biochim Biophys Acta
Title: ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
Volume: 1813
Issue: 6
Pages: 1165-71
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Publication
28869608 | J:277868
First Author: Hong F
Year: 2017
Journal: Nat Struct Mol Biol
Title: CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Volume: 24
Issue: 10
Pages: 834-839
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Publication
17707796 | J:296095
First Author: Kondratyev M
Year: 2007
Journal: Exp Cell Res
Title: PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress.
Volume: 313
Issue: 16
Pages: 3395-407
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Publication
18052927 | J:132301
First Author: Gomez E
Year: 2008
Journal: Biochem J
Title: A decrease in cellular energy status stimulates PERK-dependent eIF2alpha phosphorylation and regulates protein synthesis in pancreatic beta-cells.
Volume: 410
Issue: 3
Pages: 485-93
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Publication
23143306 | J:193979
First Author: Hart LS
Year: 2012
Journal: J Clin Invest
Title: ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
Volume: 122
Issue: 12
Pages: 4621-34
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Publication
24746698 | J:213604
First Author: Karali E
Year: 2014
Journal: Mol Cell
Title: VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress.
Volume: 54
Issue: 4
Pages: 559-72
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Publication
27802424 | J:309341
First Author: Stone S
Year: 2016
Journal: Oncotarget
Title: Dual role of the integrated stress response in medulloblastoma tumorigenesis.
Volume: 7
Issue: 39
Pages: 64124-64135
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Publication
26039714 | J:319163
First Author: Li H
Year: 2015
Journal: Cell Cycle
Title: Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner.
Volume: 14
Issue: 12
Pages: 1893-907
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Publication
11106749 | J:99455
First Author: Harding HP
Year: 2000
Journal: Mol Cell
Title: Regulated translation initiation controls stress-induced gene expression in mammalian cells.
Volume: 6
Issue: 5
Pages: 1099-108
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Publication
12667446 | J:137331
First Author: Harding HP
Year: 2003
Journal: Mol Cell
Title: An integrated stress response regulates amino acid metabolism and resistance to oxidative stress.
Volume: 11
Issue: 3
Pages: 619-33
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Publication
31320508 | J:277602
 
First Author: Chopra S
Year: 2019
Journal: Science
Title: IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.
Volume: 365
Issue: 6450
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Publication
30842412 | J:274553
First Author: Zhu H
Year: 2019
Journal: Nat Commun
Title: Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.
Volume: 10
Issue: 1
Pages: 1084
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Publication
34240701 | J:321433
   
First Author: Liu X
Year: 2021
Journal: Elife
Title: Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β-selection.
Volume: 10
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Publication
35228694 | J:333732
First Author: Raines LN
Year: 2022
Journal: Nat Immunol
Title: PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Volume: 23
Issue: 3
Pages: 431-445
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Publication
17727724 | J:129974
 
First Author: Iida K
Year: 2007
Journal: BMC Cell Biol
Title: PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.
Volume: 8
Pages: 38
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Publication
30902831 | J:277113
First Author: Gui J
Year: 2019
Journal: Mol Cancer Res
Title: The PKR-Like Endoplasmic Reticulum Kinase Promotes the Dissemination of Myc-Induced Leukemic Cells.
Volume: 17
Issue: 7
Pages: 1450-1458
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Publication
32053121 | J:301774
 
First Author: Stone S
Year: 2020
Journal: JCI Insight
Title: The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP.
Volume: 5
Issue: 5
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Publication
23022383 | J:190947
First Author: Chitnis NS
Year: 2012
Journal: Mol Cell
Title: miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner.
Volume: 48
Issue: 3
Pages: 353-64
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Publication
29295856 | J:274094
First Author: Joe Y
Year: 2018
Journal: FASEB J
Title: FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway.
Volume: 32
Issue: 5
Pages: 2630-2643
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Publication
28304100 | J:303148
First Author: Kang X
Year: 2017
Journal: J Bone Miner Res
Title: Cartilage-Specific Autophagy Deficiency Promotes ER Stress and Impairs Chondrogenesis in PERK-ATF4-CHOP-Dependent Manner.
Volume: 32
Issue: 10
Pages: 2128-2141
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Publication
24889041 | J:218077
First Author: Devi L
Year: 2014
Journal: Neurobiol Aging
Title: PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 2272-81
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Publication
21135100 | J:169485
First Author: Saito A
Year: 2011
Journal: J Biol Chem
Title: Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.
Volume: 286
Issue: 6
Pages: 4809-18
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Publication
23000413 | J:190089
First Author: Kimball SR
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2α phosphorylation, ATF4-dependent cascade.
Volume: 427
Issue: 3
Pages: 485-9
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Publication
30880003 | J:274869
First Author: Chiritoiu M
Year: 2019
Journal: Dev Cell
Title: GRASP55 and UPR Control Interleukin-1β Aggregation and Secretion.
Volume: 49
Issue: 1
Pages: 145-155.e4
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Publication
31138784 | J:279812
First Author: Starr CR
Year: 2019
Journal: Cell Death Dis
Title: Delineating the role of eIF2α in retinal degeneration.
Volume: 10
Issue: 6
Pages: 409
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Publication
10882126 | J:62257
First Author: Harding HP
Year: 2000
Journal: Mol Cell
Title: Perk is essential for translational regulation and cell survival during the unfolded protein response.
Volume: 5
Issue: 5
Pages: 897-904
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Publication
14978030 | J:218003
First Author: Cullinan SB
Year: 2004
Journal: J Biol Chem
Title: PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress.
Volume: 279
Issue: 19
Pages: 20108-17
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Publication
22240901 | J:203180
First Author: Rojas-Rivera D
Year: 2012
Journal: Cell Death Differ
Title: TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis.
Volume: 19
Issue: 6
Pages: 1013-26
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Publication
18437163 | J:150985
First Author: Novosyadlyy R
Year: 2008
Journal: Cell Death Differ
Title: Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.
Volume: 15
Issue: 8
Pages: 1304-17
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Publication
22431749 | J:185049
First Author: Byrd AE
Year: 2012
Journal: J Cell Biol
Title: MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response.
Volume: 196
Issue: 6
Pages: 689-98
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Publication
22493067 | J:185820
First Author: Bobrovnikova-Marjon E
Year: 2012
Journal: Mol Cell Biol
Title: PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.
Volume: 32
Issue: 12
Pages: 2268-78
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Publication
25113558 | J:224338
First Author: Meares GP
Year: 2014
Journal: Mol Cell Biol
Title: PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.
Volume: 34
Issue: 20
Pages: 3911-25
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Publication
29653943 | J:263884
First Author: Kang X
Year: 2018
Journal: J Biol Chem
Title: Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK-eIF-2α-CHOP pathway in the unfolded protein response.
Volume: 293
Issue: 22
Pages: 8614-8625
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Publication
16176978 | J:107108
First Author: Hamanaka RB
Year: 2005
Journal: Mol Biol Cell
Title: PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
Volume: 16
Issue: 12
Pages: 5493-501
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Publication
20660158 | J:182847
First Author: Muaddi H
Year: 2010
Journal: Mol Biol Cell
Title: Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Volume: 21
Issue: 18
Pages: 3220-31
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Publication
21385877 | J:171119
First Author: Peña J
Year: 2011
Journal: J Biol Chem
Title: Dengue virus modulates the unfolded protein response in a time-dependent manner.
Volume: 286
Issue: 16
Pages: 14226-36
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Publication
23144714 | J:225075
First Author: Mann MJ
Year: 2012
Journal: PLoS One
Title: UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.
Volume: 7
Issue: 10
Pages: e47931
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26106220 | J:259821
First Author: Kanekura K
Year: 2015
Journal: Sci Signal
Title: IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Volume: 8
Issue: 382
Pages: ra62
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Publication
33879538 | J:307142
First Author: Sidoli M
Year: 2021
Journal: J Neurosci
Title: Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy.
Volume: 41
Issue: 20
Pages: 4536-4548
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Publication
31543404 | J:283399
First Author: Chen S
Year: 2019
Journal: Cell Metab
Title: Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.
Volume: 30
Issue: 6
Pages: 1141-1151.e5
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Publication
14729979 | J:124910
First Author: Jiang HY
Year: 2004
Journal: Mol Cell Biol
Title: Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.
Volume: 24
Issue: 3
Pages: 1365-77
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Publication
27977682 | J:238714
First Author: Pytel D
Year: 2016
Journal: PLoS Genet
Title: PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.
Volume: 12
Issue: 12
Pages: e1006518
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Publication
27698114 | J:238493
First Author: Khoutorsky A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: eIF2α phosphorylation controls thermal nociception.
Volume: 113
Issue: 42
Pages: 11949-11954
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Publication
28724791 | J:290198
 
First Author: Cai Y
Year: 2017
Journal: JCI Insight
Title: Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity.
Volume: 2
Issue: 14
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Publication
28440222 | J:253375
   
First Author: Larhammar M
Year: 2017
Journal: Elife
Title: Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.
Volume: 6
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Publication
25183803 | J:216137
First Author: McAlpine CS
Year: 2014
Journal: J Lipid Res
Title: Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation.
Volume: 55
Issue: 11
Pages: 2320-33
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16352659 | J:105342
First Author: Huang G
Year: 2006
Journal: J Cell Sci
Title: ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.
Volume: 119
Issue: Pt 1
Pages: 153-61
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Publication
23152784 | J:195351
First Author: Zhang Y
Year: 2012
Journal: PLoS One
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Volume: 7
Issue: 11
Pages: e48587
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20924113 | J:165561
First Author: Papadakis AI
Year: 2010
Journal: Cancer Res
Title: eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Volume: 70
Issue: 20
Pages: 7820-9
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21044701 | J:168632
First Author: Firtina Z
Year: 2011
Journal: Gene Expr Patterns
Title: Unfolded Protein Response (UPR) is activated during normal lens development.
Volume: 11
Issue: 1-2
Pages: 135-43
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23042294 | J:189071
First Author: Upton JP
Year: 2012
Journal: Science
Title: IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
Volume: 338
Issue: 6108
Pages: 818-22
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22773666 | J:208516
First Author: Cunha DA
Year: 2012
Journal: Diabetes
Title: Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Volume: 61
Issue: 11
Pages: 2763-75
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Publication
32758541 | J:294896
 
First Author: Aryal YP
Year: 2020
Journal: Gene Expr Patterns
Title: Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development.
Volume: 37
Pages: 119130
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32294407 | J:288457
First Author: Mohamed E
Year: 2020
Journal: Immunity
Title: The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
Volume: 52
Issue: 4
Pages: 668-682.e7
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Publication
34168130 | J:341523
First Author: Vanhoutte D
Year: 2021
Journal: Nat Commun
Title: Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy.
Volume: 12
Issue: 1
Pages: 3928
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33361822 | J:305864
First Author: Kalish BT
Year: 2021
Journal: Nat Neurosci
Title: Maternal immune activation in mice disrupts proteostasis in the fetal brain.
Volume: 24
Issue: 2
Pages: 204-213
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11747369 | J:73377
First Author: Wahlin KJ
Year: 2001
Journal: Exp Eye Res
Title: Neurotrophic signaling in normal and degenerating rodent retinas.
Volume: 73
Issue: 5
Pages: 693-701
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19911006 | J:171795
First Author: Ishigaki S
Year: 2010
Journal: Cell Death Differ
Title: AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Volume: 17
Issue: 5
Pages: 774-86
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14517290 | J:85958
First Author: Cullinan SB
Year: 2003
Journal: Mol Cell Biol
Title: Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival.
Volume: 23
Issue: 20
Pages: 7198-209
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12388085 | J:82058
First Author: Kimball SR
Year: 2003
Journal: Am J Physiol Cell Physiol
Title: Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.
Volume: 284
Issue: 2
Pages: C273-84
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Publication
34124052 | J:308694
 
First Author: Tan YY
Year: 2021
Journal: Front Cell Dev Biol
Title: PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks.
Volume: 9
Pages: 670435
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19805353 | J:153222
First Author: Iwawaki T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.
Volume: 106
Issue: 39
Pages: 16657-62
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27130031 | J:315123
 
First Author: Zhong J
Year: 2016
Journal: Free Radic Biol Med
Title: Superoxide dismutase 2 overexpression alleviates maternal diabetes-induced neural tube defects, restores mitochondrial function and suppresses cellular stress in diabetic embryopathy.
Volume: 96
Pages: 234-44
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36150390 | J:330167
First Author: Mandula JK
Year: 2022
Journal: Cancer Cell
Title: Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Volume: 40
Issue: 10
Pages: 1145-1160.e9
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22961085 | J:208480
First Author: Li X
Year: 2013
Journal: Diabetes
Title: c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy.
Volume: 62
Issue: 2
Pages: 599-608
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18297134 | J:132695
First Author: Wilding Crawford L
Year: 2008
Journal: PLoS One
Title: Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis.
Volume: 3
Issue: 2
Pages: e1611
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31436800 | J:281567
First Author: Ariyasu D
Year: 2019
Journal: Endocrinology
Title: Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.
Volume: 160
Issue: 11
Pages: 2673-2691
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29056340 | J:249176
First Author: Moretti J
Year: 2017
Journal: Cell
Title: STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.
Volume: 171
Issue: 4
Pages: 809-823.e13
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30963569 | J:291194
First Author: Aryal YP
Year: 2019
Journal: J Cell Physiol
Title: An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar.
Volume: 234
Issue: 11
Pages: 20354-20365
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19858219 | J:158314
First Author: Firtina Z
Year: 2009
Journal: J Biol Chem
Title: Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.
Volume: 284
Issue: 51
Pages: 35872-84
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33060561 | J:313943
First Author: Cao S
Year: 2020
Journal: Cell Death Dis
Title: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects.
Volume: 11
Issue: 10
Pages: 859
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30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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19633360 | J:157050
First Author: Bojanic DD
Year: 2010
Journal: J Lipid Res
Title: Differential expression and function of ABCG1 and ABCG4 during development and aging.
Volume: 51
Issue: 1
Pages: 169-81
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27416896 | J:240829
 
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
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26651292 | J:240003
First Author: Laguesse S
Year: 2015
Journal: Dev Cell
Title: A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.
Volume: 35
Issue: 5
Pages: 553-67
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27106802 | J:253948
 
First Author: Magarin M
Year: 2016
Journal: J Mol Cell Cardiol
Title: Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Volume: 97
Pages: 1-14
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30655546 | J:270211
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
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19139267 | J:146172
First Author: Wang X
Year: 2009
Journal: J Cell Biol
Title: Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
Volume: 184
Issue: 1
Pages: 143-58
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17540781 | J:123644
First Author: Roma G
Year: 2007
Journal: Genome Res
Title: A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.
Volume: 17
Issue: 7
Pages: 1051-60
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26173459 | J:226104
First Author: Wang F
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development.
Volume: 309
Issue: 5
Pages: E487-99
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Publication
36841836 | J:333724
First Author: Park EJ
Year: 2023
Journal: Nat Commun
Title: Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation.
Volume: 14
Issue: 1
Pages: 1097
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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