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Search results 201 to 300 out of 366 for Hal

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Type Details Score
Publication
26813344 | J:310294
First Author: Russell SE
Year: 2016
Journal: Mucosal Immunol
Title: IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.
Volume: 9
Issue: 5
Pages: 1193-204
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Publication
28176791 | J:296074
First Author: Kovach MA
Year: 2017
Journal: Mucosal Immunol
Title: IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and -negative bacterial pneumonia.
Volume: 10
Issue: 5
Pages: 1320-1334
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Allele
Sart3<tm1.1Hbro> | MGI:5052106
Name: squamous cell carcinoma antigen recognized by T cells 3; targeted mutation 1.1, Hal E Broxmeyer
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
26361146 | J:232872
First Author: Wang J
Year: 2015
Journal: Biochem Biophys Res Commun
Title: The NLRP3 inflammasome is dispensable for ER stress-induced pancreatic β-cell damage in Akita mice.
Volume: 466
Issue: 3
Pages: 300-5
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Strain
MGI:5308090 | B6.129-Nlrp3<tm1Hhf>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
33161415 | J:313492
First Author: Shen J
Year: 2020
Journal: Cell Death Dis
Title: Membrane nanotubes facilitate the propagation of inflammatory injury in the heart upon overactivation of the β-adrenergic receptor.
Volume: 11
Issue: 11
Pages: 958
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Publication
27912077 | J:240040
First Author: Maroni L
Year: 2017
Journal: Am J Pathol
Title: Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes.
Volume: 187
Issue: 2
Pages: 366-376
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Strain
MGI:5308355 | B6N.129-Nlrp3<tm3Hhf>
Attribute String: targeted mutation, congenic, mutant strain
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Strain
MGI:5308103 | B6N.129-Nlrp3<tm3Hhf>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
- | J:180878
     
First Author: Hoffman H
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/03/01
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Publication
38308301 | J:345659
First Author: Byun DJ
Year: 2024
Journal: Cell Commun Signal
Title: NLRP3 exacerbates EAE severity through ROS-dependent NET formation in the mouse brain.
Volume: 22
Issue: 1
Pages: 96
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Strain
MGI:5308092 | B6N.129-Nlrp3<tm2Hhf>/J
Attribute String: targeted mutation, mutant strain, congenic
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Publication
25686106 | J:227935
First Author: Youm YH
Year: 2015
Journal: Nat Med
Title: The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Volume: 21
Issue: 3
Pages: 263-9
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Genotype
Genotype
Symbol: Il36rn/Il36rn Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il1rl2/Il1rl2 Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag2/Rag2 Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129S/SvEv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il1r1/Il1r1 Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il1rap/Il1rap Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3
Background: B6N.129-Nlrp3
Zygosity: hm
Has Mutant Allele: true
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Publication
27615381 | J:237111
First Author: Jansen AH
Year: 2017
Journal: Glia
Title: Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.
Volume: 65
Issue: 1
Pages: 50-61
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Publication
33334125 | J:308290
First Author: Boguslavskyi A
Year: 2021
Journal: Circulation
Title: Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans.
Volume: 143
Issue: 11
Pages: 1123-1138
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Publication
21860022 | J:178804
First Author: Vigne S
Year: 2011
Journal: Blood
Title: IL-36R ligands are potent regulators of dendritic and T cells.
Volume: 118
Issue: 22
Pages: 5813-23
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Publication
29554104 | J:260118
First Author: Palomo J
Year: 2018
Journal: PLoS One
Title: The severity of imiquimod-induced mouse skin inflammation is independent of endogenous IL-38 expression.
Volume: 13
Issue: 3
Pages: e0194667
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Publication
37744356 | J:341191
 
First Author: Kunte SC
Year: 2023
Journal: Front Immunol
Title: No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice.
Volume: 14
Pages: 1230050
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Publication
31488830 | J:279394
First Author: Giannoudaki E
Year: 2019
Journal: Nat Commun
Title: Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction.
Volume: 10
Issue: 1
Pages: 4003
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Publication
28774595 | J:296063
First Author: Jiang Z
Year: 2017
Journal: J Invest Dermatol
Title: IL-36γ Induced by the TLR3-SLUG-VDR Axis Promotes Wound Healing via REG3A.
Volume: 137
Issue: 12
Pages: 2620-2629
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Publication
31996485 | J:283735
 
First Author: Schuster-Gaul S
Year: 2020
Journal: JCI Insight
Title: ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Volume: 5
Issue: 2
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Publication
25524927 | J:230277
First Author: Toldo S
Year: 2015
Journal: Cardiovasc Res
Title: Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart.
Volume: 105
Issue: 2
Pages: 203-12
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Publication
37256935 | J:336372
First Author: Colantuoni M
Year: 2023
Journal: Sci Transl Med
Title: Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders.
Volume: 15
Issue: 698
Pages: eade3856
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Publication
30180270 | J:325303
First Author: Inzaugarat ME
Year: 2019
Journal: Hepatology
Title: NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice.
Volume: 69
Issue: 2
Pages: 845-859
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Publication
31558756 | J:279436
First Author: Ershaid N
Year: 2019
Journal: Nat Commun
Title: NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis.
Volume: 10
Issue: 1
Pages: 4375
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Publication
36641116 | J:336303
First Author: Ioannou GN
Year: 2023
Journal: J Lipid Res
Title: Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH.
Volume: 64
Issue: 2
Pages: 100330
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Publication
25477279 | J:269822
First Author: Qu C
Year: 2015
Journal: FASEB J
Title: NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
Volume: 29
Issue: 4
Pages: 1269-79
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Publication
31439870 | J:323512
First Author: Lee HE
Year: 2019
Journal: Sci Rep
Title: Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells.
Volume: 9
Issue: 1
Pages: 12277
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Publication
36405726 | J:331408
 
First Author: Peng Y
Year: 2022
Journal: Front Immunol
Title: NLRP3+ macrophages aggravate inflammatory cystitis in diabetes.
Volume: 13
Pages: 1057746
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Publication
31118442 | J:279755
First Author: Lakhdari O
Year: 2019
Journal: Sci Rep
Title: Differential Immune Activation in Fetal Macrophage Populations.
Volume: 9
Issue: 1
Pages: 7677
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Genotype
Genotype
Symbol: Il36rn/Il36rn<+> Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il1rl2/Il1rl2<+> Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
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Allele
Hal<his> | MGI:1856300
 
Name: histidine ammonia lyase; histidinemia
Allele Type: Spontaneous
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Publication
37622117 | J:347971
 
First Author: Bourne JH
Year: 2023
Journal: Front Immunol
Title: Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice.
Volume: 14
Pages: 1226196
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Publication
22968459 | J:191418
First Author: Vigne S
Year: 2012
Journal: Blood
Title: IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
Volume: 120
Issue: 17
Pages: 3478-87
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Publication
28902427 | J:318903
First Author: Wree A
Year: 2018
Journal: Hepatology
Title: NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Volume: 67
Issue: 2
Pages: 736-749
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Publication
29339122 | J:333037
First Author: Takaishi M
Year: 2018
Journal: J Invest Dermatol
Title: Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation.
Volume: 138
Issue: 6
Pages: 1439-1442
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Publication
26377915 | J:296064
 
First Author: Bozoyan L
Year: 2015
Journal: J Neuroinflammation
Title: Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis.
Volume: 12
Pages: 173
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Publication
35870427 | J:342305
 
First Author: Ma JH
Year: 2022
Journal: EBioMedicine
Title: Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model.
Volume: 82
Pages: 104184
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Publication
26216893 | J:324561
First Author: Douglas T
Year: 2015
Journal: J Immunol
Title: The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
Volume: 195
Issue: 5
Pages: 2365-73
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Publication
25405767 | J:225299
First Author: Wali JA
Year: 2014
Journal: PLoS One
Title: Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets.
Volume: 9
Issue: 11
Pages: e113128
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Strain
MGI:6384867 | B6.Cg-Nlrp3<tm2Hhf> Vsig4<tm1Gne>
Attribute String: mutant strain, targeted mutation, congenic
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Publication
24879791 | J:256722
First Author: Kajiwara Y
Year: 2014
Journal: J Immunol
Title: A critical role for human caspase-4 in endotoxin sensitivity.
Volume: 193
Issue: 1
Pages: 335-43
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Genotype
Genotype
Symbol: Il1rap/Il1rap<+> Tg(KRT14-Il1f6)1Hblu/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Tg(Zp3-cre)3Mrt/?
Background: involves: 129/Sv * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3 Vsig4/Vsig4
Background: B6.Cg-Nlrp3 Vsig4
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5905191 | STOCK Hal<his>/H
Attribute String: mutant stock, spontaneous mutation
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Genotype
Genotype
Symbol: Hal/Hal
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
11895450 | -
First Author: Baedeker M
Year: 2002
Journal: Eur J Biochem
Title: Structures of two histidine ammonia-lyase modifications and implications for the catalytic mechanism.
Volume: 269
Issue: 6
Pages: 1790-7
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Publication
7925471 | -
First Author: Appert C
Year: 1994
Journal: Eur J Biochem
Title: Structural and catalytic properties of the four phenylalanine ammonia-lyase isoenzymes from parsley (Petroselinum crispum Nym.).
Volume: 225
Issue: 1
Pages: 491-9
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Publication
16793524 | -
First Author: Rachid S
Year: 2006
Journal: Chem Biol
Title: Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.
Volume: 13
Issue: 6
Pages: 667-81
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Publication
19222035 | -
First Author: Krug D
Year: 2009
Journal: Chembiochem
Title: Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF.
Volume: 10
Issue: 4
Pages: 741-50
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Publication
11578924 | -
First Author: Poppe L
Year: 2001
Journal: Curr Opin Chem Biol
Title: Methylidene-imidazolone: a novel electrophile for substrate activation.
Volume: 5
Issue: 5
Pages: 512-24
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Publication
12667480 | -
First Author: Alunni S
Year: 2003
Journal: Arch Biochem Biophys
Title: Mechanisms of inhibition of phenylalanine ammonia-lyase by phenol inhibitors and phenol/glycine synergistic inhibitors.
Volume: 412
Issue: 2
Pages: 170-5
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Protein Domain
IPR001106 | Aromatic_Lyase
Type: Family
Description: This family includes phenylalanine ammonia-lyase, (PAL; ), histidine ammonia-lyase, (HAL; ), and tyrosine aminomutase, () [, , ].PAL and HAL are members of the Lyase class I_like superfamily of enzymes that, catalyze similar beta-elimination reactions and are active as homotetramers. Both PAL and HAL contain a catalytic Ala-Ser-Gly triad that is post-translationally cyclised []. PAL is a key biosynthetic catalyst in phenylpropanoid assembly in plants and fungi, and is involved in the biosynthesis of a wide variety of secondary metabolites such as flavanoids, furanocoumarin phytoalexins and cell wall components. These compounds are important for normal growth and in responses to environmental stress. HAL catalyses the first step in histidine degradation, the removal of an ammonia group from histidine to produce urocanic acid. The core domain in PAL and HAL share about 30% sequence identity, with PAL containing an additional approximately 160 residues extending from the common fold []. Tyrosine 2,3-aminomutase has aminomutase activity and, to a much lesser extent, ammonia-lyase activity [].PAL is being explored as enzyme substitution therapy for Phenylketonuria (PKU), a disorder which involves an inability to metabolize phenylalanine. HAL failure in humans results in the disease histidinemia [, , , ].
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Publication
26321222 | J:225959
First Author: Wang X
Year: 2015
Journal: Cancer Cell
Title: IL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses.
Volume: 28
Issue: 3
Pages: 296-306
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Publication
30742078 | J:282489
First Author: Erlich Z
Year: 2019
Journal: Nat Immunol
Title: Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model.
Volume: 20
Issue: 4
Pages: 397-406
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Publication
30388107 | J:269307
First Author: Xiao J
Year: 2018
Journal: PLoS Biol
Title: Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.
Volume: 16
Issue: 11
Pages: e3000047
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Publication
38297162 | J:347275
First Author: Shim DW
Year: 2024
Journal: Exp Mol Med
Title: Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis.
Volume: 56
Issue: 2
Pages: 370-382
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Publication
33087566 | J:297119
First Author: Ngo VL
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.
Volume: 117
Issue: 44
Pages: 27540-27548
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Publication
36505450 | J:332198
 
First Author: Wang P
Year: 2022
Journal: Front Immunol
Title: Persistent expression of NLRP3 in spinal microglia promotes development of lumbar disc degeneration.
Volume: 13
Pages: 1064303
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Publication
22558291 | J:202147
First Author: Bonar SL
Year: 2012
Journal: PLoS One
Title: Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.
Volume: 7
Issue: 4
Pages: e35979
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Publication
29531021 | J:262083
 
First Author: Huang Y
Year: 2018
Journal: EMBO Mol Med
Title: Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Volume: 10
Issue: 4
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Lyz2/Lyz2<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Lyz2/Lyz2<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Rag1/Rag1 Lyz2/Lyz2<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3 Lyz2/Lyz2<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sart3/Sart3<+> Tg(Tek-cre)1Ywa/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Protein
E0CYB6
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: false
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Protein
E0CXD3
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: false
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Publication
23643951 | -
First Author: Zhang Y
Year: 2013
Journal: Structure
Title: Structural insights into the intrinsic self-assembly of Par-3 N-terminal domain.
Volume: 21
Issue: 6
Pages: 997-1006
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Protein Domain
IPR021922 | Par3/HAL_N
Type: Domain
Description: This domain is found in eukaryotes and is about 150 amino acids in length. It has a conserved GILD sequence motif. Some proteins containing this domain are essential for cell polarity establishment and maintenance such as Par3 (partitioning defective), and some are involved in conversion of histidine into ammonia (a crucial step for forming histamine in humans) such as Histidine ammonia lyase (HAL). This N-terminal domain is found to mediate oligomerization critical for the membrane localization of Par-3. It is also found to possess a self-association capacity via a front-to-back mode in Par-3 and HAL proteins. However, unlike the Par-3 N-terminal domain which self-assembles into a left-handed helical filament, the HAL N-terminal domain does not tend to form a helical filament but rather self-assembles into circular oligomeric particles. This has been suggested to be likely due to the absence of equivalent charged residues that are essential for the longitudinal packing of the Par-3 N-terminal domain filament [].
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Publication
30662948 | J:281762
First Author: Huang X
Year: 2019
Journal: Sci Adv
Title: VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages.
Volume: 5
Issue: 1
Pages: eaau7426
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Publication
34477811 | J:327490
 
First Author: Stackowicz J
Year: 2021
Journal: J Exp Med
Title: Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
Volume: 218
Issue: 10
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Publication
28130494 | J:247745
First Author: Rhoads JP
Year: 2017
Journal: J Immunol
Title: Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.
Volume: 198
Issue: 5
Pages: 2105-2114
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Publication
33645549 | J:332779
 
First Author: Patrick GJ
Year: 2021
Journal: J Clin Invest
Title: Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
Volume: 131
Issue: 5
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Publication
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First Author: Brydges SD
Year: 2013
Journal: J Clin Invest
Title: Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.
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22904305 | J:189914
First Author: McGeough MD
Year: 2012
Journal: J Immunol
Title: Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models.
Volume: 189
Issue: 6
Pages: 2707-11
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29146733 | J:270169
First Author: Marneros AG
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Title: Effects of chronically increased VEGF-A on the aging heart.
Volume: 32
Issue: 3
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26367131 | J:246842
First Author: Guo S
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Journal: PLoS Pathog
Title: The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis.
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Pages: e1005155
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29130929 | J:273908
First Author: McGeough MD
Year: 2017
Journal: J Clin Invest
Title: TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies.
Volume: 127
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26919428 | J:230797
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Title: NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Volume: 164
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First Author: Sanchez-Lopez E
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Journal: Cell Metab
Title: Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
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First Author: Guo J
Year: 2024
Journal: Mol Immunol
Title: MS4A6D Promotes carrageenan-induced footpad swelling in mice through enhancing macrophages-derived inflammation.
Volume: 169
Pages: 28-36
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First Author: Cui S
Year: 2020
Journal: Sci Adv
Title: CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation.
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First Author: Weiss ES
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Journal: Blood
Title: Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
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35779608 | J:337222
First Author: Shahzad K
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Title: Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease.
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Title: Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.
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Journal: Elife
Title: Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization.
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