Human PARM-1 is a mucin-like, androgen-regulated transmembrane protein present in most tissues, with high levels in the heart, kidney and placenta []. It is induced and expressed in prostate after castration []and may have a role in cell proliferation and immortalisation in prostate cancer [, ]. PARM-1 also contributes toovulation and/or luteal function by acting as a novel regulator of progesterone metabolism [].