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Search results 201 to 280 out of 280 for Ddr1

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5001580
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542134
Age: embryonic day 15.5
Image: GUDMAP:8704
Specimen Label: GUDMAP:8704
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:254906
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586142
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the outer neuroblastic layer but was higher in a subset of cells.
Specimen Label: E14
Detected: true
Specimen Num: 1
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Publication
8302582 | J:17813
First Author: Perez JL
Year: 1994
Journal: Oncogene
Title: Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain.
Volume: 9
Issue: 1
Pages: 211-9
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Publication
20860797 | J:323413
 
First Author: Girgert R
Year: 2010
Journal: Fibrogenesis Tissue Repair
Title: Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney.
Volume: 3
Pages: 19
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Publication
26800565 | J:246304
First Author: Krohn JB
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Discoidin Domain Receptor-1 Regulates Calcific Extracellular Vesicle Release in Vascular Smooth Muscle Cell Fibrocalcific Response via Transforming Growth Factor-β Signaling.
Volume: 36
Issue: 3
Pages: 525-33
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Publication
20576036 | J:171784
First Author: Sturgess JE
Year: 2010
Journal: Eur J Neurosci
Title: Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects.
Volume: 32
Issue: 1
Pages: 143-54
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Publication
33930309 | J:306524
First Author: Affo S
Year: 2021
Journal: Cancer Cell
Title: Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Volume: 39
Issue: 6
Pages: 866-882.e11
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Publication
16603319 | J:108866
First Author: Franco-Pons N
Year: 2006
Journal: Neuroscience
Title: Expression of discoidin domain receptor 1 during mouse brain development follows the progress of myelination.
Volume: 140
Issue: 2
Pages: 463-75
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Publication
1281307 | J:3319
First Author: Gilardi-Hebenstreit P
Year: 1992
Journal: Oncogene
Title: An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.
Volume: 7
Issue: 12
Pages: 2499-506
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Publication
7558021 | J:27402
First Author: Bozza M
Year: 1995
Journal: Genomics
Title: Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes.
Volume: 27
Issue: 3
Pages: 412-9
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Publication
36198802 | J:339972
First Author: Filliol A
Year: 2022
Journal: Nature
Title: Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.
Volume: 610
Issue: 7931
Pages: 356-365
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Publication
8530024 | J:25776
First Author: Steingrímsson E
Year: 1995
Journal: Genomics
Title: Murine chromosomal location of five bHLH-Zip transcription factor genes.
Volume: 28
Issue: 2
Pages: 179-83
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-46577 | Interactions between Jag1 and Ddr1 in mouse liver
Series Id: GSE46577
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Ddr1<em1Smoc> | MGI:7289300
Name: discoidin domain receptor family, member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
24768818 | -
First Author: Canning P
Year: 2014
Journal: J Mol Biol
Title: Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors.
Volume: 426
Issue: 13
Pages: 2457-70
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Publication
9659899 | J:47333
First Author: Vogel W
Year: 1997
Journal: Mol Cell
Title: The discoidin domain receptor tyrosine kinases are activated by collagen.
Volume: 1
Issue: 1
Pages: 13-23
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Publication
9659900 | -
First Author: Shrivastava A
Year: 1997
Journal: Mol Cell
Title: An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.
Volume: 1
Issue: 1
Pages: 25-34
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Publication
17665456 | -
First Author: Xu L
Year: 2007
Journal: Arthritis Rheum
Title: Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis.
Volume: 56
Issue: 8
Pages: 2663-73
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Publication
24781958 | -
First Author: Márquez J
Year: 2014
Journal: Histol Histopathol
Title: Role of discoidin domain receptor 2 in wound healing.
Volume: 29
Issue: 11
Pages: 1355-64
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Publication
22328973 | -
First Author: Hammerman PS
Year: 2011
Journal: Cancer Discov
Title: Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.
Volume: 1
Issue: 1
Pages: 78-89
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Publication
20884741 | -
First Author: Roberts ME
Year: 2011
Journal: Eur Respir J
Title: Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production.
Volume: 37
Issue: 6
Pages: 1482-93
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Publication
16234985 | -
First Author: Ram R
Year: 2006
Journal: J Neurooncol
Title: Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Volume: 76
Issue: 3
Pages: 239-48
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Protein Domain
IPR034299 | DDR1/DDR2
Type: Family
Description: The discoidin domain-containing receptor (DDR) family includes DDR1 and DDR2. DDR family members are receptor tyrosine kinases (RTKs) whose activating ligands are various collagens []. The proteins contain an extracellular discoidin domain, which binds various collagen proteins, and an intracellular tyrosine kinase domain.DDR2 may have a role in wound healing; DDR2 signalling regulates cell proliferation and extracellular matrix synthesis, which are key aspects of fibroblast contribution to tissue healing []. Increased expression of DDR2 may also be important in the pathogenesis of osteoarthritis [], and there is evidence that the receptor could be implicated in certain forms of cancer - mutations in the DDR2 kinase gene have been detected in ~ 4% of squamous cell lung cancers [].Epithelial discoidin domain-containing receptor 1 (also known as DDR1) is involved in smooth muscle cell migration and matrix metalloproteinase expression []. It is responsible for maintaining the normal structure of skin and kidney epithelia []. The receptor may play a critical role in inducing tumour cell adhesion and invasion []. Itsstructure has been solved [].
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Publication
18190796 | J:133423
First Author: Hilton HN
Year: 2008
Journal: Biochim Biophys Acta
Title: KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.
Volume: 1783
Issue: 3
Pages: 383-93
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Publication
33173221 | J:300408
First Author: Wu R
Year: 2020
Journal: Sci Rep
Title: Fate and functional roles of Prominin 1+ cells in liver injury and cancer.
Volume: 10
Issue: 1
Pages: 19412
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Publication
31362952 | J:279690
 
First Author: Xu S
Year: 2019
Journal: Biol Open
Title: Discoidin domain receptor 1 deficiency in vascular smooth muscle cells leads to mislocalisation of N-cadherin contacts.
Volume: 8
Issue: 8
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Publication
32330138 | J:288096
First Author: Han T
Year: 2020
Journal: PLoS One
Title: Periostin interaction with discoidin domain receptor-1 (DDR1) promotes cartilage degeneration.
Volume: 15
Issue: 4
Pages: e0231501
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Protein
G3UXE5
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: true
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Protein
B0V2H8
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
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Protein
D6RII6
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Protein
Q62371
Organism: Mus musculus/domesticus
Length: 854  
Fragment?: false
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Protein
Q03146
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Protein
Q544T2
Organism: Mus musculus/domesticus
Length: 874  
Fragment?: false
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Protein
Q05BN5
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: true
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Protein
O35407
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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